Pomobabble: Postmodern Newspeak and Constitutional Meaning for the Uninitiated

A parody of postmodern writing

Seabeds, Soverignty And Objective Regimes

The United States and some of its major allies have been negotiating for some time concerning the establishment of an “alternative” seabed mining regime. Before confronting this issue, however, several threshold issues will be addressed. These will include descriptions of the nodule mining venture, the proposed UNCLOS regime to govern it, and the most recent developments in the U.S. backed “alternative” or reciprocating states” regime. After addressing the “objective regime” hypothesis, a strategy for avoiding potential U.S. estoppel to deny the validity of UNCLOS’ seabed mining regulations will be explored. Finally, possible scenarios for future seabed regulations and their attendant legislative and political ramifications will be explored

Spaceball (Or, Not Everything That\u27s Left is Postmodern)

Given law-school postmodernism\u27s epistemo/ontology of juvenile antirealist agnosticism, its commitment to Gadamerian and/or Derridean notions of linguistic indeterminacy, its mono- maniacal dedication to centrifugal end-justifies-the-means Lefty politics, its abhorrence of commonly recognized conceptions of neutral principle, its concomitant disrespect for the very notion of truth, and its inextricably intertwined obsession with names and propensity for linguistic doublespeak, Professor Arrow confesses to initially wondering what it might mean to take anything uttered by a postmodernist literally, or at face value. But undaunted by that \u27paradox, Professor Arrow not only takes up Feldman\u27s challenge to critique postmodernism on its own terms (by playing a pantomime Spaceball game with Feldman), but also critiques it logically--and (gasp!) pragmatically (not \u27pragmatically\u27 . Maintaining the tonal and stylistic playfulness to which law-school pomoers profess to aspire (but in no known instance have achieved), Professor Arrow assures the reader that there will be numerous interesting (not interesting\u27) plot twists along the way. In the process, Professor Arrow also offers speculation about the way in which the postmodernists\u27 ultimate contribution to American law schools is likely to be assessed-but cautions (as is appropriate under the circumstances) that you\u27ll have to find it in a footnote

Seabeds, Soverignty And Objective Regimes

The United States and some of its major allies have been negotiating for some time concerning the establishment of an “alternative” seabed mining regime. Before confronting this issue, however, several threshold issues will be addressed. These will include descriptions of the nodule mining venture, the proposed UNCLOS regime to govern it, and the most recent developments in the U.S. backed “alternative” or reciprocating states” regime. After addressing the “objective regime” hypothesis, a strategy for avoiding potential U.S. estoppel to deny the validity of UNCLOS’ seabed mining regulations will be explored. Finally, possible scenarios for future seabed regulations and their attendant legislative and political ramifications will be explored

Book Reviews

Book Reviews INTERNATIONAL ASPECTS OF CRIMINAL LAW: ENFORCING UNITED STATES LAW IN THE WORLD COMMUNITY Edited by Richard B. Lillich Charlottesville, Virginia: Michie, 1981. Pp. ix, 245. Reviewed by Stephan L. Honorg ===================== SHIPBROKING AND CHARTERING PRACTICE By Lars Gorton, RolfIhre, and Arne Sandevarn London: Lloyd\u27s of London Press,1980. Pp. xiii, 204 (authorized adapted translation of the Swedish edition of Befraktning) ================== Time CHARTERS By Michael Wilford, Terence Coghlin, and Nicholas Healy, Jr London: Lloyd\u27s of London Press, 1978. Pp.1vii, 319, £28. Reviewed by Dennis W. Arro

Antimalarial Therapy Selection for Quinolone Resistance among Escherichia coli in the Absence of Quinolone Exposure, in Tropical South America

BACKGROUND: Bacterial resistance to antibiotics is thought to develop only in the presence of antibiotic pressure. Here we show evidence to suggest that fluoroquinolone resistance in Escherichia coli has developed in the absence of fluoroquinolone use. METHODS: Over 4 years, outreach clinic attendees in one moderately remote and five very remote villages in rural Guyana were surveyed for the presence of rectal carriage of ciprofloxacin-resistant gram-negative bacilli (GNB). Drinking water was tested for the presence of resistant GNB by culture, and the presence of antibacterial agents and chloroquine by HPLC. The development of ciprofloxacin resistance in E. coli was examined after serial exposure to chloroquine. Patient and laboratory isolates of E. coli resistant to ciprofloxacin were assessed by PCR-sequencing for quinolone-resistance-determining-region (QRDR) mutations. RESULTS: In the very remote villages, 4.8% of patients carried ciprofloxacin-resistant E. coli with QRDR mutations despite no local availability of quinolones. However, there had been extensive local use of chloroquine, with higher prevalence of resistance seen in the villages shortly after a Plasmodium vivax epidemic (p<0.01). Antibacterial agents were not found in the drinking water, but chloroquine was demonstrated to be present. Chloroquine was found to inhibit the growth of E. coli in vitro. Replica plating demonstrated that 2-step QRDR mutations could be induced in E. coli in response to chloroquine. CONCLUSIONS: In these remote communities, the heavy use of chloroquine to treat malaria likely selected for ciprofloxacin resistance in E. coli. This may be an important public health problem in malarious areas

World Antimalarial Resistance Network (WARN) II: In vitro antimalarial drug susceptibility

Intrinsic resistance of Plasmodium falciparum is clearly a major determinant of the clinical failure of antimalarial drugs. However, complex interactions between the host, the parasite and the drug obscure the ability to define parasite drug resistance in vivo. The in vitro antimalarial drug susceptibility assay determines ex-vivo growth of parasite in the presence of serial drug concentrations and, thus, eliminates host effects, such as drug metabolism and immunity. Although the sensitivity of the parasite to various antimalarials provided by such a test provides an important indicator of intrinsic parasite susceptibility, there are fundamental methodological issues that undermine comparison of in vitro susceptibility both between laboratories and within a single laboratory over time. A network of laboratories is proposed that will agree on the basic parameters of the in vitro test and associated measures of quality control. The aim of the network would be to establish baseline values of sensitivity to commonly used antimalarial agents from key regions of the world, and create a global database, linked to clinical, molecular and pharmacology databases, to support active surveillance to monitor temporal trends in parasite susceptibility. Such a network would facilitate the rapid detection of strains with novel antimalarial resistance profiles and investigate suitable alternative treatments with retained efficacy