Modulation of Circumstellar Extinction in a Young Binary System with a Low-Mass Companion in a Noncoplanar Orbit

The cyclic activity model of a young star with the low-mass secondary component (q = M2/M1 <= 0.1) accreting a matter from circumbinary disk is considered. It is assumed that the orbit is circular and the disk and orbital planes are non-coplanar. Sets of hydrodynamics models of such a system have been calculated by the SPH method and then the variations of the circumstellar extinction and phase light curves were determined. The calculations showed that depending on the model parameters and orientation of the system in regards to an observer the different in shape and amplitude light curves can be observed. An important property of the considered models is also the dependence of the mass accretion rate onto the components on the phase of the orbital period. The results of the calculation can be used for analysis of the cyclic activity of UX Ori stars and young stars with the long-lasting eclipses.Comment: 14 pages, 7 figure

Реінжиніринг організаційно-технологічних процесів як чинник підвищення якості будівництва

The use of reengineering as a means of increasing the competitiveness of construction companies and increasing the efficiency of the construction process is proposed.Reengineering should not be seen as a one-time adjustment of the technological business processes of construction, but as a permanent management to improve business processes. The combination of functional flows, reducing the workflow leads to shorter construction times, lower costs for construction.Запропоновано використання реінжинірингу як засобу підвищення конкурентоспроможності будівельних компаній та підвищення ефективності процесу будівництва.Реінжиніринг повинен розглядатися не як одноразове коригування технологічних бізнес-процесів будівництва, а як постійне управління для поліпшення бізнес-процесів. Поєднання функціональних потоків, скорочення робочого процесу призводить до скорочення термінів будівництва, зниження витрат на будівництво

Christian values in spiritual and moral upbringing of students

© 2018, Ecozone, OAIMDD. All rights reserved. The issue of spiritual and moral upbringing of student-age youth is quite topical for the contemporary Science and practice. The article substantiates the necessity of spiritual and moral upbringing of the young generation on the basis of Christian values, and highlights as well as the gained experience in the implementation of the Christian values into education system of higher educational institutions. The purpose of the present study is to establish psychological patterns and mechanisms of spiritual and moral upbringing of the student‟s personality through inclusion and acceptance of Christian values. The objective of the research involves the solution of the following tasks: carrying out psychological, theoretical and methodological analysis of the problem on spiritual and moral upbringing of the personality; providing a system of psychological and pedagogical practices designed to promote spiritual and moral upbringing of the student‟s personality; and developing and testing a training program of spiritual formation of the student‟ personality. The authors have proposed the formation mechanisms of spiritual values of the student‟s personality, and developed psychological training program to form spirituality in the student‟s personality

Minimization of Fungicidal Applications Against Potato Late Blight in the North Caucasian Region: Use of the “Agrodozor” System

Late blight is considered to be the most devastating potato disease, which control requires application of fungicides able to significantly contaminate the environment and accumulate in agricultural products. Pesticide load on potato fields can be reduced via optimization of the scheme of protective treatments. Such optimization can be performed using a mathematical simulator describing the dependence of late blight-caused yield losses on the weather data and an “Agrodozor” decision support system (DSS). The performed analysis of a situation in the regions of the North Caucasus allowed us to determine three zones differing in the disease harmfulness and characterized by potential yield losses at the level of &lt;10, 10-20, and &gt;20 % and the probability of disease appearance in field during 30, 77, and 90 % of seasons, respectively. Using the “Agrodozor” DSS, we calculated the optimum dates of fungicidal treatments for these zones and showed that, comparing to the commonly used routine scheme of treatments, the use of this DSS provides a significant reduction of the number of such treatments and, therefore, the corresponding costs for their arrangement, as well as reduction of the total toxicity index of the required protective measures

Modeling the employment rate in Russia: A spatial-econometric approach

The purpose of this study is to identify factors that affect the level of employment in Russian regions. However, Russia is not a homogeneous country, and this effect may not be the same for all regions. That is why we split the regions of Russia into three groups, depending on the state of the labor market in this and neighboring regions. The HH (high-high) group comprises regions with a favorable situation in their labor markets, and which are also surrounded mostly by prosperous regions. Two groups of regions with a less favorable situation are located respectively in the south of Russia (LL1, low-low group 1) and southern Siberia and Zabaikalye (LL2, low-low group 2). We considered the twelve-year period from 2005 to 2016. As explanatory variables, we used variables for the attractiveness of the region, demographic characteristics of the region, and the degree of diversity of employees by economic activities. We tested hypotheses about differences in 1) the spatial effects and 2) the impact of the various explanatory variables for these groups of variables. To test our main hypotheses, we used spatial regression dynamic models estimated with the help of the generalized method of moments. Both main hypotheses received empirical confirmation. Spatial effects were different. The regions of the LL2 group are not affected by the situation in other local markets; regions of LL1 and HH groups are affected by the rest of Russia’s regions, and the extent of this influence decreases with the increase in geographical distance between regions. Moreover, the regions of the LL1 group compete with neighboring regions: if the situation in one of them improves, then it draws on the resources of the others. Regarding the impact of the explanatory variables, the “group effect” was revealed for the variables: share of urban population, net migration rate, shares of people below and above working age, share of people with higher education. Our results can favor the better design of national and regional policies to improve labor market performance in Russia based on the heterogeneity of the Russian regions. © Demidova O. A., Daddi P., Medvedeva E. V., Signorelli M. Text. 201

АНАЛЬГЕТИЧЕСКИЙ ПОТЕНЦИАЛ АГОНИСТОВ ПУРИНОВЫХ РЕЦЕПТОРОВ И ВИТАМИНОВ ГРУППЫ B В ЛЕЧЕНИИ ДИАБЕТИЧЕСКОЙ ПОЛИНЕЙРОПАТИИ

The efficacy and safety of purine receptor agonists in patients with chronic pain have been analysed. The data on the clinical application of purine analgesia in the management of pain syndrome are reviewed. The use of purine analgesia for the treatment of patients with chronic neuropathic pain is scientifically justified. The central mechanisms of purine receptor agonists and their analgesic activity are described in detail. It has been shown that purine receptor agonists have a strong analgesic effect and a narrow range of side effects, and they effectively relieve neuropathic pain by influencing the purinergic regulatory mechanism. The mechanisms of the analgesic effect of B vitamins (B1, B6, B12) that have their own analgesic potential are considered — which is of great importance in the pharmacotherapy of polyneuropathies. It should be noted that the prescription of B vitamins is pathogenetically justified in diabetic polyneuropathy, and a combination of B vitamins is more efficacious than a monotherapy.Проанализированы эффективность и безопасность агонистов пуриновых рецепторов у пациентов с хронической болью. Проведен обзор данных о клиническом применении пуриновой анальгезии в купировании болевого синдрома. Научно обосновано использование пуриновой анальгезии для лечения пациентов с хронической нейропатической болью. Подробно описаны центральные механизмы агонистов пуриновых рецепторов и их анальгетическая активность. Показано, что агонисты пуриновых рецепторов отличаются сильным анальгетическим действием, узким спектром побочных эффектов и, воздействуя на пуринергический регуляторный механизм, эффективно купируют нейропатическую боль. Рассмотрены механизмы анальгетического эффекта витаминов группы В (В1, В6, В12), обладающих собственным анальгетическим потенциалом, что имеет важное значение в фармакотерапии полинейропатий. Отмечается, что при диабетической полинейропатии назначение витаминов группы В патогенетически обосновано, при этом подчеркивается, что комбинация витаминов группы В более эффективна, чем монотерапия

НАПРЯМИ УДОСКОНАЛЕННЯ ДІЯЛЬНОСТІ ФОНДУ ГАРАНТУВАННЯ ВКЛАДІВ ФІЗИЧНИХ ОСІБ: ЕКОНОМІКО-ПРАВОВИЙ АСПЕКТ

The features of the activities of the Deposit Guarantee Fund within the system of guaranteeing deposits of individuals have been studied in the article. The powers of the Deposit Guarantee Fund have been analyzed. It has been determined that its executive directorate exercises powers in the sphere of providing the Fund’s activity, in respect of sources of the formation of the Fund’s assets, in the sphere of deposit repayment, in the sphere of regulatory activity, in the field of withdrawing insolvent banks from the market. It has been offered to divide the powers of the administrative council of the Deposit Guarantee Fund into functional, conciliatory and regulatory ones. The problems of forming the resource base of the Deposit Guarantee Fund have been clarified. It has been emphasized that the expansion of the sources for the formation of the Fund’s assets is directly related to the range of participants of the system of individuals’ deposits guaranteeing. In order to increase the funds of the Deposit Guarantee Fund, it has been offered to include non-bank financial institutions into the Fund’s participants. Some aspects of control over the activity of the Deposit Guarantee Fund have been studied. It has been emphasized that the Fund’s annual report needs to be improved. It has been offered to consolidate the form of the annual report of the Fund in the legislation and to define the following its sections: main indicators of the Fund’s activity in the reporting period, internal management of the Fund, legislation and regulatory activity, public information, analysis of the banking sector, regulatory activity of the Fund, financial management, withdrawal of insolvent banks from the market, protection of depositors’ interests, the Fund’s financial reports. The directions for improving the Fund’s activity have been formulated, namely revision of the Fund’s powers in terms of exercising control over troubled banks, expanding the range of subjects and objects of the deposit guaranteeing system, improving control over the Fund’s activities, introducing new mechanisms for repayment to depositors of insolvent banks, expanding the list of sources for the formation of the Fund’s assets.Исследованы особенности деятельности Фонда гарантирования вкладов физических лиц в системе гарантирования вкладов физических лиц. Проанализированы полномочия Фонда гарантирования вкладов физических лиц. Выяснены проблемы формирования ресурсной базы Фонда гарантирования вкладов физических лиц. Указано, что расширение источников формирования средств Фонда гарантирования вкладов физических лиц напрямую связано с кругом участников системы гарантирования вкладов физических лиц. Рассмотрены отдельные аспекты контроля за деятельностью Фонда гарантирования вкладов физических лиц. Сформулированы направления совершенствования деятельности Фонда гарантирования вкладов физических лиц.Досліджено особливості діяльності Фонду гарантування вкладів фізичних осіб у системі гарантування вкладів фізичних осіб. Проаналізовано повноваження Фонду гарантування вкладів фізичних осіб. Визначено, що його виконавча дирекція здійснює повноваження у сфері забезпечення діяльності Фонду, щодо джерел формування коштів Фонду, у сфері забезпечення відшкодувань за вкладами, у сфері регуляторної діяльності, у сфері виведення неплатоспроможних банків з ринку. Запропоновано повноваження адміністративної ради Фонду гарантування вкладів фізичних осіб поділити на функціональні,&nbsp;погоджувальні і&nbsp;розпорядчі. З’ясовано проблеми формування ресурсної бази Фонду гарантування вкладів фізичних осіб. Наголошено, що розширення джерел формування коштів Фонду безпосередньо пов’язано з колом учасників системи гарантування вкладів фізичних осіб. З метою збільшення коштів Фонду гарантування вкладів фізичних осіб запропоновано включити до складу учасників Фонду небанківські фінансові установи. Розглянуто окремі аспекти контролю за діяльністю Фонду гарантування вкладів фізичних осіб. Наголошено, що річний звіт Фонду потребує вдосконалення. Запропоновано закріпити форму річного звіту Фонду в законодавстві та визначити такі його розділи: основні показники діяльності Фонду у звітному періоді, внутрішнє управління Фонду, законодавство та регуляторна діяльність, інформування громадськості, аналіз банківського сектору, регулятивна діяльність Фонду, управління фінансами, виведення неплатоспроможних банків з ринку, захист інтересів вкладників, фінансова звітність Фонду. Сформульовано напрямами удосконалення діяльності Фонду, а саме: перегляд повноважень Фонду в частині здійснення контролю за проблемними банками, розширення кола суб’єктів та об’єктів системи гарантування вкладів, удосконалення контролю за діяльністю Фонду, запровадження нових механізмів здійснення виплат відшкодування вкладникам неплатоспроможних банків, розширення переліку джерел формування коштів Фонду

Comparative Analysis of Drug Interactions with Antibacterial Agents in the Treatment of Community-Acquired Pneumonia

According to the World Health Organisation, pneumonia and other lower respiratory tract infections are one of the leading causes of death all over the world. Simultaneous treatment of pneumonia with antibacterial drugs and concomitant medicines may result in adverse drug reactions (ADRs). The aim of the study was to analyse ADRs resulting from drug-drug interactions in different empiric antibiotic treatment regimens used for mild community-acquired pneumonia (CAP), taking into account the concomitant symptomatic non-antibacterial treatment and chronic disease treatment. Materials and methods: the authors analysed spontaneous reports in the VigiBase global database (starting from the date the database was created and until 15 February 2021) on ADRs resulting from interactions of medicinal products included in the Russian clinical guidelines for CAP.Results: the authors compiled a list of antibacterial drugs (amoxicillin+clavulanic acid, amoxicillin, ampicillin, azithromycin, clarithromycin, levofloxacin, moxifloxacin, cefotaxime, ceftriaxone, linezolid), as well as lists of medicinal products for symptomatic and concomitant treatment, based on the approved guidelines for management of CAP and frequent comorbid chronic diseases. They searched VigiBase for ADRs that may have resulted from drug-drug interactions involving these medicinal products. Conclusions: the analysis of adverse reactions used for mild CAP treatment demonstrated that the largest number of ADRs were associated with drug-drug interactions involving azithromycin, while the smallest number of ADRs were associated with cefotaxime and ceftriaxone. Further study of drug-drug interactions will help to prevent potential ADRs, identify rational drug combinations, and improve the existing patient management strategies

Formation of 24Mg* in the Splitting of 28Si Nuclei by 1-GeV Protons

The 28Si(p, p' gamma)24Mg reaction has been studied at the ITEP accelerator by the hadron-gamma coincidence method for a proton energy of 1 GeV. Two reaction products are detected: a 1368.6-keV gamma-ray photon accompanying the transition of the 24Mg* nucleus from the first excited state to the ground state and a proton p' whose momentum is measured in a magnetic spectrometer. The measured distribution in the energy lost by the proton in interaction is attributed to five processes: the direct knockout of a nuclear alpha cluster, the knockout of four nucleons with a total charge number of 2, the formation of the DeltaSi isobaric nucleus, the formation of the Delta isobar in the interaction of the incident proton with a nuclear nucleon, and the production of a pi meson, which is at rest in the nuclear reference frame. The last process likely corresponds to the reaction of the formation of a deeply bound pion state in the 28P nucleus. Such states were previously observed only on heavy nuclei. The cross sections for the listed processes have been estimated.Comment: 14 pages, 3 figures submitted to JETP Letter