NEMA NU 2-2007 performance characteristics of GE Signa integrated PET/MR for different PET isotopes

BackgroundFully integrated PET/MR systems are being used frequently in clinical research and routine. National Electrical Manufacturers Association (NEMA) characterization of these systems is generally done with F-18 which is clinically the most relevant PET isotope. However, other PET isotopes, such as Ga-68 and Y-90, are gaining clinical importance as they are of specific interest for oncological applications and for follow-up of Y-90-based radionuclide therapy. These isotopes have a complex decay scheme with a variety of prompt gammas in coincidence. Ga-68 and Y-90 have higher positron energy and, because of the larger positron range, there may be interference with the magnetic field of the MR compared to F-18. Therefore, it is relevant to determine the performance of PET/MR for these clinically relevant and commercially available isotopes.MethodsNEMA NU 2-2007 performance measurements were performed for characterizing the spatial resolution, sensitivity, image quality, and the accuracy of attenuation and scatter corrections for F-18, Ga-68, and Y-90. Scatter fraction and noise equivalent count rate (NECR) tests were performed using F-18 and Ga-68. All phantom data were acquired on the GE Signa integrated PET/MR system, installed in UZ Leuven, Belgium.Results(18)F, Ga-68, and Y-90 NEMA performance tests resulted in substantially different system characteristics. In comparison with F-18, the spatial resolution is about 1mm larger in the axial direction for Ga-68 and no significative effect was found for Y-90. The impact of this lower resolution is also visible in the recovery coefficients of the smallest spheres of Ga-68 in image quality measurements, where clearly lower values are obtained. For Y-90, the low number of counts leads to a large variability in the image quality measurements. The primary factor for the sensitivity change is the scale factor related to the positron emission fraction. There is also an impact on the peak NECR, which is lower for Ga-68 than for F-18 and appears at higher activities.ConclusionsThe system performance of GE Signa integrated PET/MR was substantially different, in terms of NEMA spatial resolution, image quality, and NECR for Ga-68 and Y-90 compared to F-18. But these differences are compensated by the PET/MR scanner technologies and reconstructions methods

On Pulsar Distance Measurements and their Uncertainties

Accurate distances to pulsars can be used for a variety of studies of the Galaxy and its electron content. However, most distance measures to pulsars have been derived from the absorption (or lack thereof) of pulsar emission by Galactic HI gas, which typically implies that only upper or lower limits on the pulsar distance are available. We present a critical analysis of all measured HI distance limits to pulsars and other neutron stars, and translate these limits into actual distance estimates through a likelihood analysis that simultaneously corrects for statistical biases. We also apply this analysis to parallax measurements of pulsars in order to obtain accurate distance estimates and find that the parallax and HI distance measurements are biased in different ways, because of differences in the sampled populations. Parallax measurements typically underestimate a pulsar's distance because of the limited distance to which this technique works and the consequential strong effect of the Galactic pulsar distribution (i.e. the original Lutz-Kelker bias), in HI distance limits, however, the luminosity bias dominates the Lutz-Kelker effect, leading to overestimated distances because the bright pulsars on which this technique is applicable are more likely to be nearby given their brightness.Comment: 32 pages, 1 figure, 2 tables; Accepted for publication in the Astrophysical Journa

VLBI astrometry of PSR J2222-0137: a pulsar distance measured to 0.4% accuracy

The binary pulsar J2222-0137 is an enigmatic system containing a partially recycled millisecond pulsar and a companion of unknown nature. Whilst the low eccentricity of the system favors a white dwarf companion, an unusual double neutron star system is also a possibility, and optical observations will be able to distinguish between these possibilities. In order to allow the absolute luminosity (or upper limit) of the companion object to be properly calibrated, we undertook astrometric observations with the Very Long Baseline Array to constrain the system distance via a measurement of annual geometric parallax. With these observations, we measure the parallax of the J2222-0137 system to be 3.742 +0.013 -0.016 milliarcseconds, yielding a distance of 267.3 +1.2 -0.9 pc, and measure the transverse velocity to be 57.1 +0.3 -0.2 km/s. Fixing these parameters in the pulsar timing model made it possible to obtain a measurement of Shapiro delay and hence the system inclination, which shows that the system is nearly edge-on (sin i = 0.9985 +/- 0.0005). Furthermore, we were able to detect the orbital motion of J2222-0137 in our VLBI observations and measure the longitude of ascending node. The VLBI astrometry yields the most accurate distance obtained for a radio pulsar to date, and is furthermore the most accurate parallax for any radio source obtained at "low" radio frequencies (below ~5 GHz, where the ionosphere dominates the error budget). Using the astrometric results, we show the companion to J2222-0137 will be easily detectable in deep optical observations if it is a white dwarf. Finally, we discuss the implications of this measurement for future ultra-high-precision astrometry, in particular in support of pulsar timing arrays.Comment: 22 pages, 7 figures, accepted for publication in Ap

B835: Landfills and Municpal Solid Waste in Maine

Municipal leaders need current information about alternative disposal methods to make rational decisions on handling their town\u27s waste. To provide an overview of landfilling and other waste-handling methods used in the upper New England states, a group of university researchers from New Hampshire, Maine, and Vermont initiated a study of landfills and solid waste management practices. The study involved a comprehensive mail survey of municipalities in Maine, New Hampshire, and Vermont. This report focuses upon and discusses the results of the landfill and solid waste management survey for Maine.https://digitalcommons.library.umaine.edu/aes_bulletin/1019/thumbnail.jp

Searching for the spectral depolarisation of ASKAP one-off FRB sources

Fast Radio Bursts (FRBs) are extragalactic transients of (sub-)millisecond duration that show wide-ranging spectral, temporal, and polarimetric properties. The polarimetric analysis of FRBs can be used to probe intervening media, study the emission mechanism, and test possible progenitor models. In particular, low-frequency depolarization of FRBs can identify dense, turbulent, magnetized, ionized plasma thought to be near the FRB progenitor. An ensemble of repeating FRBs has shown low-frequency depolarization. The depolarization is quantified by the parameter σRM⁠, which correlates with proxies for both the turbulence and mean magnetic field strength of the putative plasma. However, while many non-repeating FRBs show comparable scattering (and hence inferred turbulence) to repeating FRBs, it is unclear whether their surrounding environments are comparable to those of repeating FRBs. To test this, we analyse the spectro-polarimetric properties of five one-off FRBs and one repeating FRB, detected and localized by the Australian Square Kilometer Array Pathfinder. We search for evidence of depolarization due to σRM and consider models where the depolarization is intrinsic to the source. We find no evidence (for or against) the sample showing spectral depolarization. Under the assumption that FRBs have multipath propagation-induced depolarization, the correlation between our constraint on and RM is consistent with repeating FRBs only if the values of σRM are much smaller than our upper limits. Additionally, the correlation between the constraints on σRM and τs is inconsistent with repeating FRBs. The observations provide further evidence for differences in the typical environments and sources of one-off and repeating FRBs

Universal dynamics of rogue waves in a quenched spinor Bose condensate

Universal scaling dynamics of a many-body system far from equilibrium signals the proximity of the time-evolution to a non-thermal fixed point. We find universal dynamics connected with rogue-wave like events in the mutually coupled magnetic components of a spinor gas which propagate in an effectively random potential. The frequency of these caustics is affected by the time varying spatial correlation length of the potential, giving rise to an additional exponent $\delta_\mathrm{c} \simeq 1/3$ for temporal scaling, which is different by a factor $\sim 4/3$ from the exponent $\beta_V \simeq 1/4$ characterizing the scaling of the correlation length $\ell_V \sim t^{\,\beta_V}$ with time. As a result of the caustics, real-time instanton defects appear in the Larmor phase of the spin-1 system as vortices in space and time. The temporal correlations determining the frequency of instanton events to occur scale in time as $t^{\, \delta_\mathrm{I}}$. This suggests that the universality class of a non-thermal fixed point could be characterized by different, mutually related exponents defining the coarsening evolution in time and space, respectively. Our results have a strong relevance for understanding pattern coarsening from first principles and potential implications for dynamics ranging from the early universe to geophysical dynamics and micro physics

The first resolved imaging of milliarcsecond-scale jets in Circinus X-1

We present the first resolved imaging of the milliarcsecond-scale jets in the neutron star X-ray binary Circinus X-1, made using the Australian Long Baseline Array. The angular extent of the resolved jets is ~20 milliarcseconds, corresponding to a physical scale of ~150 au at the assumed distance of 7.8 kpc. The jet position angle is relatively consistent with previous arcsecond-scale imaging with the Australia Telescope Compact Array. The radio emission is symmetric about the peak, and is unresolved along the minor axis, constraining the opening angle to be less than 20 degrees. We observe evidence for outward motion of the components between the two halves of the observation. Constraints on the proper motion of the radio-emitting components suggest that they are only mildly relativistic, although we cannot definitively rule out the presence of the unseen, ultra-relativistic (Lorentz factor >15) flow previously inferred to exist in this system.Comment: Accepted for publication in MNRAS Letters. 6 pages, 4 figure

The blazar-like radio structure of the TeV source IC310

Context. The radio galaxy IC310 in the Perseus cluster has recently been detected in the gamma-ray regime at GeV and TeV energies. The TeV emission shows time variability and an extraordinarily hard spectrum, even harder than the spectrum of the similar nearby gamma-ray emitting radio galaxy M87. Aims. High-resolution studies of the radio morphology help to constrain the geometry of the jet on sub-pc scales and to find out where the high-energy emission might come from. Methods. We analyzed May 2011 VLBA data of IC310 at a wavelength of 3.6 cm, revealing the parsec-scale radio structure of this source. We compared our findings with more information available from contemporary single-dish flux density measurements with the 100-m Effelsberg radio telescope. Results. We have detected a one-sided core-jet structure with blazar-like, beamed radio emission oriented along the same position angle as the kiloparsec scale radio structure observed in the past by connected interferometers. Doppler-boosting favoritism is consistent with an angle of theta < 38 degrees between the jet axis and the line-of-sight, i.e., very likely within the boundary dividing low-luminosity radio galaxies and BL Lac objects in unified schemes. Conclusions. The stability of the jet orientation from parsec to kiloparsec scales in IC310 argues against its classification as a headtail radio galaxy; i.e., there is no indication of an interaction with the intracluster medium that would determine the direction of the tail. IC310 seems to represent a low-luminosity FRI radio galaxy at a borderline angle to reveal its BL Lac-type central engine.Comment: 5 pages, 3 figures (1 color); A&A, accepte