Présence de Mesocyclops rarus Kiefer, 1981 (Crustacé, Copépode) au Sénégal

#Mesocyclops rarus$ Kiefer, 1981, copépode cyclopide d'eau douce, connu de l'est africain jusqu'au Tibesti, est trouvé pour la première fois au Sénégal. L'aire de distribution de cette espèce est ainsi considérablement étendue. (Résumé d'auteur

Metacyclops hannensis n. sp. (Crustacea, Decapoda, Cyclopoïda), un cyclopide nouveau du Sénégal

#Metacyclops shannensis n. sp. est décrit du Sénégal. Une clé pour les #Metacyclops africains est fournie, d'après la bibliographie existante. (Résumé d'auteur

Compléments à la faune des crustacés copépodes des eaux intérieures de Guyane française

De nouveaux échantillons de microfaune aquatique provenant de Guyane française élèvent le nombre d'espèces de crustacés copépodes connus des eaux intérieures de la région de 10 à 33. Parmi celles-ci, six sont nouvelles pour la science dont un calanoïde et quatre cyclopoïdes. Les Harpacticoïdes trouvés sont peu nombreux mais particulièrement intéressants du point de vue biogéographique. La plupart des espèces citées sont illustrées afin de permettre les comparaisons ultérieures. (Résumé d'auteur

On the Taxonomy of the Acanthocyclops robustus Species-Complex (Copepoda, Cyclopidae): Acanthocyclops brevispinosus and A. einslei sp. n

Приведены новые сведения по морфологии Acanthocyclops brevispinosus (Herrick, 1884). Вид, ранее ошибочно идентифицировавшийся как A. robustus (sensu Petkovski, 1975; Kiefer, 1976; Einsle, 1997 и др.), описан в качестве нового вида A. einslei Mirabdullayev & Defaye, sp. n. Приведены данные по распространению и изменчивости.New data on morphology of Acanthocyclops brevispinosus (Herrick, 1884) are provided. A. einslei Mirabdullayev & Defaye, sp. n., previously misidentified as (sensu Petkovski, 1975; Kiefer, 1976; Einsle, 1997 et al.) is described

The Crustacean Fauna (Branchiopoda, Copepoda) of Shallow Freshwater Bodies in Iceland

A survey of shallow freshwaters of Iceland was conducted in June and July 1996. The 34 stations prospected were rainpools, ditches, wetlands. The composition of their crustacean communities, investigated by qualitative net samples, is discussed in relation to water characteristics. One notostracan, Lepidurus arcticus (Pallas, 1793), 17 cladoceran species (5 Daphniidae, 10 Chydoridae, 1 Macrothricidae, 1 Polyphemidae), and 12 copepods (2 Diaptomidae, 7 Cyclopidae, 3 Canthocamptidae) were identified. Two species are reported for the first time from Iceland: the diaptomid Diaptomus (Chaetodiaptomus) rostripes Herbst, 1955 and the chydorid Alona rustica Scott, 1895. Taxonomical comments about different species are added, and their ecological pecularities are given. The species richness as well as the biogeographical features of the freshwater zooplankton of Iceland are discussed in relation to neighbouring Greenland and Northern Europe.Обследование мелких пресных водоемов Исландии проведено в июне-июле 1996 г. Материал собирался в дождевых и талых лужах, канавах, болотах. Среди 30 обнаруженных видов отмечены 1 вид щитней Lepidurus arcticus (Pallas, 1793), 17 видов ветвистоусых ракообразных (5 представителей сем. Daphnidae, 10 Chydoridae, 1 Macrothricidae, 1 Polyphemidae), 12 видов веслоногих ракобразных (2 вида сем. Diaptomidae, 7 Cyclopidae, 3 Canthocamptidae). Два вида указаны впервые для фауны Исландии: Diaptomus (Chaetodiatomus) rostripes Herbst, 1955 и Alona rustica Scott, 1895. Состав ракообразных в водоемах обсуждается в связи с экологической характеристикой последних. Для отдельных видов представлены краткие таксономические и экологические замечания. Обсуждаются видовое разнообразие и биогеографические особенности Исландии в связи с фаунистическими контактами с Гренландией и северной Европой

First inappropriate implantable cardioverter defibrillator therapy is often due to inaccurate device programming: analysis of the French OPERA registry

AIMS:Inappropriate therapy delivered by implantable cardioverter defibrillators (ICDs) remains a challenge. The OPERA registry measured the times to, and studied the determinants of, first appropriate (FAT) and inappropriate (FIT) therapies delivered by single-, dual- and triple-chamber [cardiac resynchronization therapy defibrillator (CRT-D)] ICD. METHODS AND RESULTS: We entered 636 patients (mean age = 62.0 ± 13.5 years; 88% men) in the registry, of whom 251 received single-, 238 dual-, and 147 triple-chamber ICD, for primary (30.5%) or secondary (69.5%) indications. We measured times to FAT and FIT as a function of multiple clinical characteristics, examined the effects of various algorithm components on the likelihood of FAT and FIT delivery, and searched for predictors of FAT and FIT. Over 22.8 ± 8.8 months of observation, 184 patients (28.9%) received FAT and 70 (11.0%) received FIT. Ventricular tachycardia (VT) was the trigger of 88% of FAT, and supraventricular tachycardia was the trigger of 91% of FIT. The median times to FIT (90 days; range 49-258) and FAT (171 days; 50-363) were similar. The rate of FAT was higher (P <0.001) in patients treated for secondary than primary indications, while that of FIT were similar in both groups. Out of 57 analysable FIT, 27 (47.4%) could have been prevented by fine tuning the device programming like the sustained rate duration or the VT discrimination algorithm. CONCLUSIONS: First inappropriate therapy occurred in 11% of 636 ICD recipients followed for ∼2 years. Nearly 50% of FIT could have been prevented by improving device programming

Implantable cardioverter defibrillator therapy for primary prevention of sudden cardiac death in the real world: Main findings from the French multicentre DAI-PP programme (pilot phase)

This review summarizes the main findings of the French multicentre DAI-PP pilot programme, and discusses the related clinical and research perspectives. This project included retrospectively (2002–2012 period) more than 5000 subjects with structural heart disease who received an implantable cardioverter defibrillator (ICD) for primary prevention of sudden cardiac death, and were followed for a mean period of 3 years. The pilot phase of the DAI-PP programme has provided valuable information on several practical and clinically relevant aspects of primary prevention ICD implantation in the real-world population, which are summarized in this review. This pilot has led to a prospective evaluation that started in May 2018, assessing ICD therapy in primary and secondary prevention in patients with structural and electrical heart diseases, with remote monitoring follow-up using a dedicated platform. This should further enhance our understanding of sudden cardiac death, to eventually optimize the field of preventative actions

Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection: Long-Term Results of an International Multicenter Study

Introduction: Data regarding the efficacy of catheter ablation in patients with atrial fibrillation (AF) and patients' previous history of pulmonary lobectomy/pneumonectomy are scanty. We sought to evaluate the efficacy and long-term follow-up of catheter ablation in this highly selected group of patients. Material and Methods: Twenty consecutive patients (8 females, 40%; median age 65.2 years old) with a history of pneumonectomy/lobectomy and paroxysmal or persistent AF, treated by means of pulmonary vein isolation (PVI) at ten participating centers were included. Procedural success, intra-procedural complications, and AF recurrences were considered. Results: Fifteen patients had a previous lobectomy and five patients had a complete pneumonectomy. A large proportion (65%) of PV stumps were electrically active and represented a source of firing in 20% of cases. PVI was performed by radiofrequency ablation in 13 patients (65%) and by cryoablation in the remaining 7 cases. Over a median follow up of 29.7 months, a total of 7 (33%) AF recurrences were recorded with neither a difference between patients treated with cryoablation or radiofrequency ablation or between the two genders. Conclusions: Catheter ablation by radiofrequency ablation or cryoablation in patients with pulmonary stumps is feasible and safe. Long-term outcomes are favorable, and a similar efficacy of catheter ablation has been noticed in both males and females

Device complications with addition of defibrillation to cardiac resynchronisation therapy for primary prevention

Objective: In patients indicated for cardiac resynchronisation therapy (CRT), the choice between a CRT-pacemaker (CRT-P) versus defibrillator (CRT-D) remains controversial and indications in this setting have not been well delineated. Apart from inappropriate therapies, which are inherent to the presence of a defibrillator, whether adding defibrillator to CRT in the primary prevention setting impacts risk of other acute and late device-related complications has not been well studied and may bear relevance for device selection. // Methods: Observational multicentre European cohort study of 3008 consecutive patients with ischaemic or non-ischaemic dilated cardiomyopathy and no history of sustained ventricular arrhythmias, undergoing CRT implantation with (CRT-D, n=1785) or without (CRT-P, n=1223) defibrillator. Using propensity score and competing risk analyses, we assessed the risk of significant device-related complications requiring surgical reintervention. Inappropriate shocks were not considered except those due to lead malfunction requiring lead revision. // Results: Acute complications occurred in 148 patients (4.9%), without significant difference between groups, even after considering potential confounders (OR=1.20, 95% CI 0.72 to 2.00, p=0.47). During a mean follow-up of 41.4±29 months, late complications occurred in 475 patients, giving an annual incidence rate of 26 (95% CI 9 to 43) and 15 (95% CI 6 to 24) per 1000 patient-years in CRT-D and CRT-P patients, respectively. CRT-D was independently associated with increased occurrence of late complications (HR=1.68, 95% CI 1.27 to 2.23, p=0.001). In particular, when compared with CRT-P, CRT-D was associated with an increased risk of device-related infection (HR 2.10, 95% CI 1.18 to 3.45, p=0.004). Acute complications did not predict overall late complications, but predicted device-related infection (HR 2.85, 95% CI 1.71 to 4.56, p<0.001). // Conclusions: Compared with CRT-P, CRT-D is associated with a similar risk of periprocedural complications but increased risk of long-term complications, mainly infection. This needs to be considered in the decision of implanting CRT with or without a defibrillator

Relative Roles of the Cellular and Humoral Responses in the Drosophila Host Defense against Three Gram-Positive Bacterial Infections

BACKGROUND: Two NF-kappaB signaling pathways, Toll and immune deficiency (imd), are required for survival to bacterial infections in Drosophila. In response to septic injury, these pathways mediate rapid transcriptional activation of distinct sets of effector molecules, including antimicrobial peptides, which are important components of a humoral defense response. However, it is less clear to what extent macrophage-like hemocytes contribute to host defense. METHODOLOGY/PRINCIPAL FINDINGS: In order to dissect the relative importance of humoral and cellular defenses after septic injury with three different gram-positive bacteria (Micrococcus luteus, Enterococcus faecalis, Staphylococcus aureus), we used latex bead pre-injection to ablate macrophage function in flies wildtype or mutant for various Toll and imd pathway components. We found that in all three infection models a compromised phagocytic system impaired fly survival--independently of concomitant Toll or imd pathway activation. Our data failed to confirm a role of the PGRP-SA and GNBP1 Pattern Recognition Receptors for phagocytosis of S. aureus. The Drosophila scavenger receptor Eater mediates the phagocytosis by hemocytes or S2 cells of E. faecalis and S. aureus, but not of M. luteus. In the case of M. luteus and E. faecalis, but not S. aureus, decreased survival due to defective phagocytosis could be compensated for by genetically enhancing the humoral immune response. CONCLUSIONS/SIGNIFICANCE: Our results underscore the fundamental importance of both cellular and humoral mechanisms in Drosophila immunity and shed light on the balance between these two arms of host defense depending on the invading pathogen