12 research outputs found
Integrated capacity and production planning in the pharmaceutical supply chain: framework and models
Phenomena Based Methodology for Process Synthesis Incorporating Process Intensification
Process intensification (PI) has the potential to improve
existing
as well as conceptual processes, in order to achieve a more sustainable
production. PI can be achieved at different levels, that is the unit
operations, functional, and/or phenomena level. The highest impact
is expected by looking at processes at the lowest level of aggregation
which is the phenomena level. In this paper, a phenomena based synthesis/design
methodology incorporating process intensification is presented. Using
this methodology, a systematic identification of necessary and desirable
(integrated) phenomena as well as generation and screening of phenomena
based flowsheet options are presented using a decomposition based
solution approach. The developed methodology as well as necessary
tools and supporting methods are highlighted through a case study
involving the production of isopropyl acetate