Eddy current testing of ferromagnetic materials: modelling of multiple flows in a planar stratified medium

International audienceFollowing a previous work carried out at the laboratory in the case of one flaw located in a cylindrical ferromagnetic piece, the development presented herein address the case of multiple interacting flaws located inside a planar, stratified and ferromagnetic medium. Simulation results are obtained through the application of the Volume Integral Method (VIM)

CONCUR Test-Of-Time Award 2020 Announcement

This short article announces the recipients of the CONCUR Test-of-Time Award 2020

Accurate Simulation of EMAT Probes for Ultrasonic NDT Based on Experimental Measurements

During the last years, CEALIST has been developing EMATprobes dedicated to liquid sodium ultrasound applications, including telemetry, defect detection in sodium immersed welds, defect sizing, andmore recently using phased array probes, beam forming images and synthetic focusing. At the same time, simulation tools based on the numerical methods available at CEA LIST have been integrated within the CIVA software platform. This paper focuses on the experimental calibration of the simulation models for liquid sodium EMAT transducers. In particular, it tries to answer the questions regarding choices of input data for the developed models with the goal of carrying out realistic simulations. The full system measurement model, including coil impedances, gains and analog filters need to be taken into account to obtain predictive simulations. Physical measurements allow the precise determination of the needed parameters and allow verifying the different aspects of the EMAT probe behavior. The developed model is then used to propose a design that is optimized with respect to the generation of longitudinal waves in liquid sodium

A global modeling approach of the leakage phenomena in dielectrics

Thanks to its low noise level, the LSBB environment provides particular environment to carry out high quality electrical characterizations. In this paper, we propose a complete modeling approach of the experimental results from our experimental microelectronic setup. The tested device is a Metal Oxide Semiconductor (MOS) floating gate capacitor which can be found in electrostatic non volatile memories such as Flash. The main idea is to characterize and model the leakage current through the tunnel oxide. We proposed, in a previous work, a model for charge loss considering a fractional Poisson process, involving only two parameters, expressed as a Mittag-Leffler (ML) function. Here, we also propose a combo of Fowler-Nordheim (FN) and Poole-Frenkel (PF) models for leakage currents, based on tunnel effect transport through the oxide. It gives the leakage current on a medium-to-long scale of time while the ML model can possibly take into account a shorter time step. The perspective is to find a relationship between these different models, used in various fields, to propose a generic model of phenomena involving leakage in complex and porous materials at different scales of time and space

Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer

This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2010 Patani.Background: Ubiquitin modification of proteins influences cellular processes relevant to carcinogenesis. CHIP (carboxyl-terminus of Hsc70-interacting protein) is a chaperone-dependent E3 ubiquitin ligase, regulating the stability of heat shock protein 90 (HSP90) interacting proteins. CHIP is implicated in the modulation of estrogen receptor (ESR1) and Her-2/neu (ERBB2) stability. LOX (lysyl-oxidase) serves intracellular roles and catalyses the cross-linking of extracellular matrix (ECM) collagens and elastin. LOX expression is altered in human malignancies and their peri-tumoral stroma. However, paradoxical roles are reported. In this study, the level of mRNA expression of CHIP and LOX were assessed in normal and malignant breast tissue and correlated with clinico-pathological parameters. Materials and Methods: Breast cancer (BC) tissues (n = 127) and normal tissues (n = 33) underwent RNA extraction and reverse transcription; transcript levels were determined using real-time quantitative PCR and normalized against CK-19. Transcript levels were analyzed against TNM stage, nodal involvement, tumor grade and clinical outcome over a ten-year follow-up period. Results: CHIP expression decreased with increasing Nottingham Prognostic Index (NPI): NPI-1 vs. NPI-3 (12.2 vs. 0.2, P = 0.0264), NPI-2 vs. NPI-3 (3 vs. 0.2, P = 0.0275). CHIP expression decreased with increasing TNM stage: TNM-1 vs. TNM-2 (12 vs. 0, P = 0.0639), TNM-1 vs. TNM-2-4 (12 vs. 0, P = 0.0434). Lower transcript levels were associated with increasing tumor grade: grade 1 vs. grade 3 (17.7 vs. 0.3, P = 0.0266), grade 2 vs. grade 3 (5 vs. 0.3, P = 0.0454). The overall survival (OS) for tumors classified as ‘low-level expression’, was poorer than those with ‘high-level expression’ (118.1 vs. 152.3 months, P = 0.039). LOX expression decreased with increasing NPI: NPI-1 vs. NPI-2 (3 vs. 0, P = 0.0301) and TNM stage: TNM-1 = 3854639, TNM-2 = 908900, TNM-3 = 329, TNM-4 = 1.232 (P = NS). Conclusion: CHIP expression is associated with favorable prognostic parameters, including tumor grade, TNM stage and NPI. CHIP expression predicts OS. LOX expression is associated with improved NPI. In addition to their prognostic utility, mechanistic insights into tumor suppressor function may offer potential therapeutic strategies

Design, Construction and In Situ Testing of a Muon Camera for Earth Science and Civil Engineering Applications

The MUST2 (MUon Survey Tomography based on Micromegas detectors for Unreachable Sites Technology) camera is based on a thin Time Projection Chamber read by a resistive Micromegas. This innovative combination presents interesting distinctive features compared to existing muon detection technologies. It allows a wide angular acceptance of the detector with a low weight and compact volume, well adapted for confined spaces or underground operation. The current work presents the results obtained during the calibration measurements at the reference site, the Low Background Noise Laboratory (LBNL). Preliminary results from field measurement campaign carried out at the dam overlooking the village of Saint-Saturnin-les-Apt (South-East of France) are presented and discussed

CONCUR Test-of-time award 2020 announcement

This short article announces the recipients of the CONCUR Test-of-Time Award 2020

Variations de la composition isotopique du lithium dans les péridotites océaniques serpentinisées et dans le manteau : implications pour le cycle du lithium

Texte intégral accessible uniquement aux membres de l'Université de LorraineNon disponible / Not availableLa composition isotopique du lithium est un bon traceur des processus hydrothermaux dans la croûte océanique du fait de sa mobilité et de son fractionnement isotopique lors des interactions fluide-roche. Il est aussi un traceur potentiel de la subduction de la croûte océanique dans le manteau. Les études précédentes sur le comportement du lithium lors de l'hydrothermalisme ont été limitées à l'altération des basaltes. Or les péridotites serpentinisées représentent une proportion non négligeable de la croûte océanique et doivent être prises en compte dans le cycle du lithium. Les péridotites serpentinisées étudiées ont été draguées le long de la ride Sud Ouest Indienne au cours de la campagne EDUL en 1997. Leurs teneurs et leurs compositions isotopiques en lithium ont été déterminées sur roches totales par spectrométrie de masse classique et in situ sur les différents minéraux par sonde ionique. Les résultats montrent que ce processus d'altération représente un puits de lithium pour l'océan. Les valeurs isotopiques globales des serpentines exprimées en [delta] 6Li sont comprises entre -14 et -3 [pour mille] et suggèrent que le lithium qu'elles contiennent provient plutôt de la croûte océanique que de l'eau de mer. Parallèlement, nous avons également analysé par sonde ionique une série de verres basaltiques provenant de différents contextes : MORB, OIB, BABB, afin de préciser la distribution du lithium dans le manteau et son comportement lors de la subduction de la croûte altérée. Les données obtenues indiquent que la composition isotopique de la source profonde des OIB est comparable à celle des MORB, mais qu'elle présente des hétérogénéités isotopiques importantes, mettant en évidence la subduction en profondeur d'une partie du lithium incorporé dans la croûte océanique lors de son altération. Ces résultats apportent de nouvelles données concernant d'une part l'influence de la serpentinisation sur le budget du lithium dans l'eau de mer et d'autre part son recyclage dans le manteau