Running Wheel Accessibility Affects the Regional Electroencephalogram during Sleep in Mice

Regional aspects of sleep homeostasis were investigated in mice provided with a running wheel for several weeks. Electroencephalogram (EEG) spectra of the primary motor (frontal) and somatosensory cortex (parietal) were recorded for three consecutive days. On a single day (day 2) the wheel was locked to prevent running. Wheel running correlated negatively with the frontal-parietal ratio of slow-wave activity (EEG power between 0.75 and 4.0 Hz) in the first 2 h after sleep onset (r = −0.60; P < 0.01). On day 2 frontal EEG power (2.25-8.0 Hz) in non-rapid eye movement sleep exceeded the level of the previous day, indicating that the diverse behaviors replacing wheel-running elicited more pronounced regional EEG differences. The frontal-parietal power ratio of the lower frequency bin (0.75-1.0 Hz) in the first 2 h of sleep after dark onset correlated positively with the duration of the preceding waking (r = 0.64; P < 0.001), whereas the power ratio in the remaining frequencies of the delta band (1.25-4.0 Hz) was unrelated to waking. The data suggest that in mice EEG power in the lower frequency, corresponding to the slow oscillations described in cats and humans, is related to local sleep homeostasi

Scientific objectives and first results from COMPTEL

The imaging Compton telescope (COMPTEL) is the first imaging telescope in space to explore the MeV gamma ray range. At present it is performing a complete sky survey. In later phases of the mission, selected celestial objects will be studied in more detail. Targets of special interest in the COMPTEL energy range are radio pulsars, X-ray binaries, novae, supernova remnants, molecular clouds, and the interstellar medium within the Milky Way, as well as the nuclei of active galaxies, supernovae, and the diffuse cosmic background radiation in extragalactic space. The first four months of operation demonstrated that COMPTEL basically performs as expected. The Crab is clearly seen at its proper position in the first images of the anticenter region of the Galaxy. The Crab pulsar lightcurve was measured with unprecedented accuracy. The quasar 3C273 was seen for the first time at MeV-energies. Several cosmic bursts within the COMPTEL field of view could be located to an accuracy of about 1 degree. On June 9, 11, and 15, 1991 COMPTEL observed gamma ray (continuum and line) emission from three solar flares. Neutrons were also detected from the June 9 flare. At the present state of analysis, COMPTEL achieves the prelaunch predictions of its sensitivity within a factor of 2. Based on the present performance of COMPTEL, the team is confident that COMPTEL will fulfill its primary mission of surveying and exploring the MeV sky

Economics of robots and automation in field crop production

This study reviewed research published after 1990 on the economics of agricultural mechatronic automation and robotics, and identified research gaps. A systematic search was conducted from the following databases: ScienceDirect, Business Source Complete, Wiley, Emerald, CAB Abstract, Greenfile, Food Science Source and AgEcon Search. This identified 4817 documents. The screening of abstracts narrowed the range to a dataset of 119 full text documents. After eligibility assessment, 18 studies were subjected to a qualitative analysis, with ten focused on automation of specific horticultural operations and eight related to autonomous agricultural equipment. All of the studies found some scenarios in which automation and robotic technologies were profitable. Most studies employed partial budgeting considering only costs and revenues directly changed by the introduction of automation or robotics and assuming everything else constant. None examined cropping system changes, or regional and national impacts on markets, trade and labour demand. The review identified a need for in-depth research on the economic implications of the technology. Most of the studies reviewed estimated economic implications assuming that technology design parameters were achieved and/or based on data from prototypes. Data are needed on the benefits and problems with using automation and robotics on farm. All of the studies reviewed were in the context of agriculture in developed countries, but many of the world’s most pressing agricultural problems are in the developing world. Economic and social research is needed to understand those developing country problems, and guide the engineers and scientists creating automation and robotic solutions

Activation in the COMPTEL double-scattering gamma-ray telescope

Abstract-The COMPTEL gamma-ray telescope has been operating in low Earth orbit for six years, since the launch of the Compton Gamma-Ray Observatory in April 1991. Comparisons of data for different orbits and epochs show evidence of activation on time scales from minutes (27Mg, q,2=9.5 min) to years C2Na, q&.58 yr). The activation is correlated with both the orbital altitude and solar cosmic-ray modulation. Because it requires coincident measurements in two different detectors, COMPTEL is most susceptible to instrumental background events in which two or more photons are produced simultaneously

An Architectural Approach to Autonomics and Self-management of Automotive Embedded Electronic Systems

International audienceEmbedded electronic systems in vehicles are of rapidly increasing commercial importance for the automotive industry. While current vehicular embedded systems are extremely limited and static, a more dynamic configurable system would greatly simplify the integration work and increase quality of vehicular systems. This brings in features like separation of concerns, customised software configuration for individual vehicles, seamless connectivity, and plug-and-play capability. Furthermore, such a system can also contribute to increased dependability and resource optimization due to its inherent ability to adjust itself dynamically to changes in software, hardware resources, and environment condition. This paper describes the architectural approach to achieving the goals of dynamically self-configuring automotive embedded electronic systems by the EU research project DySCAS. The architecture solution outlined in this paper captures the application and operational contexts, expected features, middleware services, functions and behaviours, as well as the basic mechanisms and technologies. The paper also covers the architecture conceptualization by presenting the rationale, concerning the architecture structuring, control principles, and deployment concept. In this paper, we also present the adopted architecture V&V strategy and discuss some open issues in regards to the industrial acceptance

Unruh Radiation, Holography and Boundary Cosmology

A uniformly acclerated observer in anti-deSitter space-time is known to detect thermal radiation when the acceleration exceeds a critical value. We investigate the holographic interpretation of this phenomenon. For uniformly accelerated trajectories transverse to the boundary of the AdS space, the hologram is a blob which expands along the boundary. Observers on the boundary co-moving with the hologram become observers in cosmological space-times. For supercritical accelerations one gets a Milne universe when the holographic screen is the boundary in Poincare coordinates, while for the boundary in hyperspherical coordinates one gets deSitter spacetimes. The presence or absence of thermality is then interpreted in terms of specific classes of observers in these cosmologies.Comment: LaTeX, 35 pages, 3 figures. A reference is added and typos are correcte

COMPTEL observations of the inner galaxy

This paper presents a first global study of COMPTEL observations of the inner Galaxy in the energy range 0.75–10 MeV. Preliminary findings demonstrate COMPTEL’s capabilities for mapping the observed gamma radiation and disentangling the contributions from point sources and diffuse emission

Technologies of sleep research

Sleep is investigated in many different ways, many different species and under many different circumstances. Modern sleep research is a multidisciplinary venture. Therefore, this review cannot give a complete overview of all techniques used in sleep research and sleep medicine. What it will try to do is to give an overview of widely applied techniques and exciting new developments. Electroencephalography has been the backbone of sleep research and sleep medicine since its first application in the 1930s. The electroencephalogram is still used but now combined with many different techniques monitoring body and brain temperature, changes in brain and blood chemistry, or changes in brain functioning. Animal research has been very important for progress in sleep research and sleep medicine. It provides opportunities to investigate the sleeping brain in ways not possible in healthy volunteers. Progress in genomics has brought new insights in sleep regulation, the best example being the discovery of hypocretin/orexin deficiency as the cause of narcolepsy. Gene manipulation holds great promise for the future since it is possible not only to investigate the functions of different genes under normal conditions, but also to mimic human pathology in much greater detail