17 research outputs found

    Polar UVI images to study steady magnetospheric convection events: Initial results

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94804/1/grl20687.pd

    Perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care (LAFA trial)

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    BACKGROUND: Recent developments in large bowel surgery are the introduction of laparoscopic surgery and the implementation of multimodal fast track recovery programs. Both focus on a faster recovery and shorter hospital stay. The randomized controlled multicenter LAFA-trial (LAparoscopy and/or FAst track multimodal management versus standard care) was conceived to determine whether laparoscopic surgery, fast track perioperative care or a combination of both is to be preferred over open surgery with standard care in patients having segmental colectomy for malignant disease. METHODS/DESIGN: The LAFA-trial is a double blinded, multicenter trial with a 2 × 2 balanced factorial design. Patients eligible for segmental colectomy for malignant colorectal disease i.e. right and left colectomy and anterior resection will be randomized to either open or laparoscopic colectomy, and to either standard care or the fast track program. This factorial design produces four treatment groups; open colectomy with standard care (a), open colectomy with fast track program (b), laparoscopic colectomy with standard care (c), and laparoscopic surgery with fast track program (d). Primary outcome parameter is postoperative hospital length of stay including readmission within 30 days. Secondary outcome parameters are quality of life two and four weeks after surgery, overall hospital costs, morbidity, patient satisfaction and readmission rate. Based on a mean postoperative hospital stay of 9 +/- 2.5 days a group size of 400 patients (100 each arm) can reliably detect a minimum difference of 1 day between the four arms (alfa = 0.95, beta = 0.8). With 100 patients in each arm a difference of 10% in subscales of the Short Form 36 (SF-36) questionnaire and social functioning can be detected. DISCUSSION: The LAFA-trial is a randomized controlled multicenter trial that will provide evidence on the merits of fast track perioperative care and laparoscopic colorectal surgery in patients having segmental colectomy for malignant disease

    Outcomes of elective liver surgery worldwide: a global, prospective, multicenter, cross-sectional study

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    Background: The outcomes of liver surgery worldwide remain unknown. The true population-based outcomes are likely different to those vastly reported that reflect the activity of highly specialized academic centers. The aim of this study was to measure the true worldwide practice of liver surgery and associated outcomes by recruiting from centers across the globe. The geographic distribution of liver surgery activity and complexity was also evaluated to further understand variations in outcomes. Methods: LiverGroup.org was an international, prospective, multicenter, cross-sectional study following the Global Surgery Collaborative Snapshot Research approach with a 3-month prospective, consecutive patient enrollment within January–December 2019. Each patient was followed up for 90 days postoperatively. All patients undergoing liver surgery at their respective centers were eligible for study inclusion. Basic demographics, patient and operation characteristics were collected. Morbidity was recorded according to the Clavien–Dindo Classification of Surgical Complications. Country-based and hospital-based data were collected, including the Human Development Index (HDI). (NCT03768141). Results: A total of 2159 patients were included from six continents. Surgery was performed for cancer in 1785 (83%) patients. Of all patients, 912 (42%) experienced a postoperative complication of any severity, while the major complication rate was 16% (341/2159). The overall 90-day mortality rate after liver surgery was 3.8% (82/2,159). The overall failure to rescue rate was 11% (82/ 722) ranging from 5 to 35% among the higher and lower HDI groups, respectively. Conclusions: This is the first to our knowledge global surgery study specifically designed and conducted for specialized liver surgery. The authors identified failure to rescue as a significant potentially modifiable factor for mortality after liver surgery, mostly related to lower Human Development Index countries. Members of the LiverGroup.org network could now work together to develop quality improvement collaboratives

    FTA: A Feature Tracking Empirical Model of Auroral Precipitation

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    The Feature Tracking of Aurora (FTA) model was constructed using 1.5 years of Polar Ultraviolet Imager data and is based on tracking a cumulative energy grid in 96 magnetic local time (MLT) sectors. The equatorward boundary, poleward boundary, and 19 cumulative energy bins are tracked with the energy flux and the latitudinal position. With AE increasing, the equatorward boundary moves to lower latitudes everywhere, while the poleward boundary moves poleward in the 2300–0300 MLT region and equatorward in other MLT sectors. This results in the aurora getting wider on the nightside and becoming narrower on the dayside. The peak intensity of the aurora in each MLT sector is almost linearly related to AE, with the global peak moving from pre‐midnight to post‐midnight as geomagnetic activity increases. Ratios between the Lyman‐Birge‐Hopfield‐long and ‐short models allow the average energy to be calculated. Predictions from the FTA and two other auroral models were compared to the measurements by the Defense Meteorological Satellite Program Special Sensor Ultraviolet Spectrographic Imagers (SSUSI) on March 17, 2013. Among the three models, the FTA model specified the most confined patterns with the highest energy flux, agreeing with the spatial and temporal evolution of SSUSI measurements better and predicted auroral power (AP) better during higher activity levels (SSUSI AP > 20 GW). The Fuller‐Rowell and Evans (1987) and FTA models specified very similar average energy compared with SSUSI measurements, doing slightly better by ∌1 keV than the OVATION Prime model.Key PointsThe AE‐based Feature Tracking of Aurora (FTA) model provides the energy flux and the average energy using 1.5 years of Polar Ultraviolet Imager dataThe FTA model’s grid is tied to auroral boundaries and spatial distribution: tracking a cumulative energy grid in each magnetic local time sectorFor the March 17, 2013 event, the FTA model had the most confined patterns and agreed best with Special Sensor Ultraviolet Spectrographic Imagers observations of auroral powerPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/167826/1/swe21144.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/167826/2/swe21144_am.pd
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