Short-Term Orchestral Music Training Modulates Hyperactivity and Inhibitory Control in School-Age Children: A Longitudinal Behavioural Study

Survey studies have shown that participating in music groups produces several benefits, such as discipline, cooperation and responsibility. Accordingly, recent longitudinal studies showed that orchestral music training has a positive impact on inhibitory control in school-age children. However, most of these studies examined long periods of training not always feasible for all families and institutions and focused on children’s measures ignoring the viewpoint of the teachers. Considering the crucial role of inhibitory control on hyperactivity, inattention and impulsivity, we wanted to explore if short orchestral music training would promote a reduction of these impulsive behaviors in children. This study involved 113 Italian children from 8 to 10 years of age. 55 of them attended 3 months of orchestral music training. The training included a 2-hour lesson per week at school and a final concert. The 58 children in the control group did not have any orchestral music training. All children were administered tests and questionnaires measuring inhibitory control and hyperactivity near the beginning and end of the 3-month training period. We also collected information regarding the levels of hyperactivity of the children as perceived by the teachers at both time points. Children in the music group showed a significant improvement in inhibitory control. Moreover, in the second measurement the control group showed an increase in self-reported hyperactivity that was not found in the group undergoing the music training program. This change was not noticed by the teachers, implying a discrepancy between self-reported and observed behavior at school. Our results suggest that even an intense and brief period of orchestral music training is sufficient to facilitate the development of inhibitory control by modulating the levels of self-reported hyperactivity. This research has implications for music pedagogy and education especially in children with high hyperactivity. Future investigations will test whether the findings can be extended to children diagnosed with ADHD

Evidence of Luttinger liquid behavior in one-dimensional dipolar quantum gases

The ground state and structure of a one-dimensional Bose gas with dipolar repulsions is investigated at zero temperature by a combined Reptation Quantum Monte Carlo (RQMC) and bosonization approach. A non trivial Luttinger-liquid behavior emerges in a wide range of intermediate densities, evolving into a Tonks-Girardeau gas at low density and into a classical quasi-ordered state at high density. The density dependence of the Luttinger exponent is extracted from the numerical data, providing analytical predictions for observable quantities, such as the structure factor and the momentum distribution. We discuss the accessibility of such predictions in current experiments with ultracold atomic and molecular gases.Comment: 4 pages, 3 EPS figures, Revtex

Application of Paper-Based Microfluidic Analytical Devices (μPAD) in Forensic and Clinical Toxicology: A Review

The need for providing rapid and, possibly, on-the-spot analytical results in the case of intoxication has prompted researchers to develop rapid, sensitive, and cost-effective methods and analytical devices suitable for use in nonspecialized laboratories and at the point of need (PON). In recent years, the technology of paper-based microfluidic analytical devices (μPADs) has undergone rapid development and now provides a feasible, low-cost alternative to traditional rapid tests for detecting harmful compounds. In fact, μPADs have been developed to detect toxic molecules (arsenic, cyanide, ethanol, and nitrite), drugs, and drugs of abuse (benzodiazepines, cathinones, cocaine, fentanyl, ketamine, MDMA, morphine, synthetic cannabinoids, tetrahydrocannabinol, and xylazine), and also psychoactive substances used for drug-facilitated crimes (flunitrazepam, gamma-hydroxybutyric acid (GHB), ketamine, metamizole, midazolam, and scopolamine). The present report critically evaluates the recent developments in paper-based devices, particularly in detection methods, and how these new analytical tools have been tested in forensic and clinical toxicology, also including future perspectives on their application, such as multisensing paper-based devices, microfluidic paper-based separation, and wearable paper-based sensors

Modulating the water oxidation catalytic activity of iridium complexes by functionalizing the Cp*-ancillary ligand: hints on the nature of the active species

The catalytic activity toward NaIO4driven water oxidation of a series of [RCp*IrCl(μ-Cl)]2dimeric precursors, containing tetramethylcyclopentadienyl ligands with a variable R substituent (H,1; Me,2; Et,3;nPr,4; CH2CH2NH3+,5; Ph,6; 4-C6H4F,7; 4-C6H4OH,8; Bn,9), has been evaluated at 298 K and pH = 7 (with phosphate buffer). For each dimer, the effect of changing the catalyst (1-10 μM) and NaIO4(5-40 mM) concentration has been studied. All precursors exhibit a high activity with TOF values ranging from 101 min−1to 393 min−1and TON values being always those expected assuming a 100% yield. The catalytic activity was strongly affected by the nature of the R substituent. The highest TOF values were observed when R was electron-donating and small. The results of multiple consecutive injection experiments suggest that a fragment of the initial C5Me4R, still bearing the R-substituent, remains attached at iridium in the active species, despite the oxidativein situdegradation of the same ligand. The decrease of TOF in the second and third catalytic runs was completely ascribed to a drop of the redox potential caused by the conversion of IO4−into IO3−, according to the Nernst equation. This hypothesis was verified by performing catalytic experiments in which the initial redox potential (ΔE) was deliberately varied by using water solutions of IO4−/IO3−mixtures at different relative concentrations. Consistently, TOFversusΔEplots show that, for a given catalyst, the same TOF is obtained at a certain redox potential, irrespective of the initial reaction conditions used. All seems to indicate that after a short activation period, during which the transformation of the precursors occurs, individual active species for each dimer form and remain the same also after multiple additions of the sacrificial oxidant. It can be speculated that such active species are small iridium clusters bearing R-functionalized likelyO,O-bidentate ligands

Phase fluctuations in superconductors: from Galilean invariant to quantum XY models

We analyze the corrections to the superfluid density due to phase fluctuations within both a continuum and a lattice model for $s$- and d-wave superconductors. We expand the phase-only action beyond the Gaussian level and compare our results with the quantum XY model both in the quantum and in the classical regime. We find new dynamic anharmonic vertices, absent in the quantum XY model, which are responsible for the vanishing of the correction to the superfluid density at zero temperature in a continuum (Galilean invariant) model. Moreover the phase-fluctuation effects are reduced with respect to the XY model by a factor at least of order $1/(k_F\xi_0)^2$.Comment: 4 pages; shorter version, accepted for publication on Phys. Rev. B Rapid Com

Increase in number of the gap junctions between satellite neuroglial cells during lifetime: An ultrastructural study in rabbit spinal ganglia from youth to extremely advanced age

This study investigated quantitative aspects of the gap junctions between satellite neuroglial cells that envelope the spinal ganglion neurons in rabbits aged 1 year (young), 3.6 years (adult), 6.7 years (old), and 8.8 years (very old). Both the total number of gap junctions present in 30,000 mu m(2) of surface area occupied by perineuronal satellite cells, and the density of these junctions increased throughout life, including the extremely advanced age. By contrast, the mean length of individual gap junctions did not change with age. Thus, the junctional system which provides morphological support for the metabolic cooperation between satellite cells in rabbit spinal ganglia becomes more extensive as the age of the animal increases. These results support the hypothesis that the gap junctions between perineuronal satellite cells are involved in the spatial buffering of extracellular K(+) and in neuroprotection

The perineuronal glial tissue of spinal ganglia : quantitative changes in the rabbit from youth to extremely advanced age

The volumes of the nerve cell bodies and those of the enveloping satellite cell sheaths from spinal ganglia were determined by morphometric methods applied to electron micrographs in young, adult, old and very old rabbits. The mean volume of the nerve cell bodies increased progressively with age; this is probably related to the increase with age of the body size of the rabbits studied. The mean volume of the satellite cell sheaths did not differ significantly in young, adult and old animals, but was significantly smaller in very old animals. It is extremely unlikely that this marked reduction in the volume of the satellite cell sheath is the result of a pathological process. The mean value of the volume ratio between the satellite cell sheaths and the related nerve cell bodies did not differ significantly in young and adult animals, but was significantly smaller in old and very old animals. This ratio was particularly low in very old animals. Our analysis showed that in each age group the volume of the satellite cell sheath is linearly related to the volume of the related nerve cell body. This result suggests that in rabbit spinal ganglia the quantitative relations between glial and nervous tissue are tightly controlled throughout life. It is suggested that ganglionic neurons release signals to influence and control the volume of their associated glial tissue. Since satellite cells have important support roles for the neurons they surround, it is likely that the marked reduction in the volume of perineuronal sheaths in the extremely advanced age is accompanied by a reduction of those roles, with negative consequences for neuronal activity

Use of healthy emulsion hydrogels to improve the quality of pork burgers

The present research evaluated the use of oil mixture emulsion hydrogels as animal fat replacers and their effect on the physicochemical, nutritional and sensory characteristics of pork burgers. Three different types of burgers were manufactured: control (samples elaborated with 100% pork fat), T1 and T2 (pork fat totally replaced by emulsion hydrogels of walnut or pistachio oil and algal oil, respectively). Fat replacement increased the moisture and ash contents and colour parameters (L* and b*) of pork burgers. Modified samples turned out to be firmer and chewier than those in the control group. The addition of oil emulsion hydrogels caused a significant decrease in fat and energy contents and the products obtained can be considered “reduced fat content”. Moreover, the content of saturated fatty acids decreased, while mono- and polyunsaturated fatty acids increased, constituting an improvement in health indices. Sensory differences were found between the samples and T2 was the most preferred for flavour and overall. However, both modified burgers had good levels of acceptability. To conclude, the use of the proposed oil mixture emulsion hydrogels as pork backfat substitutes represents a promising strategy to obtain healthier pork burgers without negatively affecting technological or sensory properties.The authors thank GAIN (Axencia Galega de Innovación) for supporting this research (grant number IN607A2019/01)

The low-energy phase-only action in a superconductor: a comparison with the XY model

The derivation of the effective theory for the phase degrees of freedom in a superconductor is still, to some extent, an open issue. It is commonly assumed that the classical XY model and its quantum generalizations can be exploited as effective phase-only models. In the quantum regime, however, this assumption leads to spurious results, such as the violation of the Galilean invariance in the continuum model. Starting from a general microscopic model, in this paper we explicitly derive the effective low-energy theory for the phase, up to fourth-order terms. This expansion allows us to properly take into account dynamic effects beyond the Gaussian level, both in the continuum and in the lattice model. After evaluating the one-loop correction to the superfluid density we critically discuss the qualitative and quantitative differences between the results obtained within the quantum XY model and within the correct low-energy theory, both in the case of s-wave and d-wave symmetry of the superconducting order parameter. Specifically, we find dynamic anharmonic vertices, which are absent in the quantum XY model, and are crucial to restore Galilean invariance in the continuum model. As far as the more realistic lattice model is concerned, in the weak-to-intermediate-coupling regime we find that the phase-fluctuation effects are quantitatively reduced with respect to the XY model. On the other hand, in the strong-coupling regime we show that the correspondence between the microscopically derived action and the quantum XY model is recovered, except for the low-density regime.Comment: 29 pages, 11 figures. Slightly revised presentation, accepted for publication in Phys. Rev.

Dynamic correlations in symmetric electron-electron and electron-hole bilayers

The ground-state behavior of the symmetric electron-electron and electron-hole bilayers is studied by including dynamic correlation effects within the quantum version of Singwi, Tosi, Land, and Sjolander (qSTLS) theory. The static pair-correlation functions, the local-field correction factors, and the ground-state energy are calculated over a wide range of carrier density and layer spacing. The possibility of a phase transition into a density-modulated ground state is also investigated. Results for both the electron-electron and electron-hole bilayers are compared with those of recent diffusion Monte Carlo (DMC) simulation studies. We find that the qSTLS results differ markedly from those of the conventional STLS approach and compare in the overall more favorably with the DMC predictions. An important result is that the qSTLS theory signals a phase transition from the liquid to the coupled Wigner crystal ground state, in both the electron-electron and electron-hole bilayers, below a critical density and in the close proximity of layers (d <~ r_sa_0^*), in qualitative agreement with the findings of the DMC simulations.Comment: 13 pages, 11 figures, 2 table