Social movements: development actors in Bolivia? : a case study of how "Cocaleros" movements perceive their role in Bolivian development processes

Masteroppgave development management- Universitetet i Agder 2010In the last decades the Bolivian social movements started gaining force and raising their voices against the injustices and the inefficiency of the governments to give solution to their problems. During the last 20 years the movements have started to gain control and force, but many of the movements have a longer history. One of them is the cocaleros movement, the coca leaf growers’ movement. They spent more than thirty years fighting for what they considered to be their rights; they practically started form cero and created a strong organization that represents not only their particular interests, but the collective identity of their people. This thesis, based on a six months research among the cocaleros communities, academicians and civil society shows how this social movement emerged, how it has evolved over time and how its leaders managed to create perhaps the strongest social movement in the history of Bolivia. The cocaleros movement was the first social movement that created a ‘political instrument’ (the political party MAS), a party that won for the second time in the Bolivian history, with majority, the national presidential elections. As such, the movement has truly assisted in giving Bolivia its first indigenous president, the former cocalero leader Evo Morales. This thesis explores how the members of the cocaleros movement perceive their role in the Bolivian society; how they feel the impacts of their actions have changed Bolivia. The thesis will also discuss whether they are really changing the Bolivian context or if they are merely following a political discourse. Finally, the thesis also describes the way this social movement is seen by other sectors of society, sectors who may or may not agree with the new government that is somehow closely related to the cocaleros social movement

Culturally relevant science: An approach to math science education for Hispanics

This report describes later stages of a program to develop culturally relevant science and math programs for Hispanic students. Part of this effort was follow-up with 17 teachers who participated in early stages of the program. Response was not very good. Included with the report is a first draft effort for curriculum materials which could be used as is in such a teaching effort. Several of the participating teachers were invited to a writing workshop, where lesson plans were drafted, and critiqued and following rework are listed in this publication. Further work needs to be completed and is ongoing

Porphyrinogenic activity and ferrochelatase-inhibitory activity of sydnones in chick embryo liver cells

Abstract3-[2-(2,4,6-Trimethylphenyl)thioethyl]-4-methylsydnone was shown to be a potent porphyrinogenic agent in chick embryo liver cells. The accumulation of protoporphyrin IX was consistent with the finding that ferrochelatase activity was inhibited. 3-Benzyl-4-phenylsydnone did not inhibit ferrochelatase activity and protoporphyrin IX was found to constitute only a minor fraction of the porphyrins. These results support the idea that the porphyrinogenicity of 3-[2-(2,4,6-trimethylphenyl)thioethyl]-4-methylsydnone is due to its catalytic activation by cytochrome P-450 leading to heme alkylation and formation of N-vinylprotoporphyrin IX which inhibits ferrochelatase

Human Heme Oxygenase Oxidation of 5- and 15-Phenylhemes

Human heme oxygenase-1 (hHO-1) catalyzes the O2- dependent oxidation of heme to biliverdin, CO, and free iron. Previous work indicated that electrophilic addition of the terminal oxygen of the ferric hydroperoxo complex to the -meso-carbon gives 5-hydroxyheme. Earlier efforts to block this reaction with a 5-methyl substituent failed, as the reaction still gave biliverdin IX . Surprisingly, a 15-methyl substituent caused exclusive cleavage at the -meso- rather than at the normal, unsubstituted -meso-carbon. No CO was formed in these reactions, but the fragment cleaved from the porphyrin eluded identification. We report here that hHO-1 cleaves 5-phenylheme to biliverdin IX and oxidizes 15- phenylheme at the -meso position to give 10-phenylbiliverdin IX . The fragment extruded in the oxidation of 5-phenylheme is benzoic acid, one oxygen of which comes from O2 and the other from water. The 2.29- and 2.11-Å crystal structures of the hHO-1 complexes with 1- and 15-phenylheme, respectively, show clear electron density for both the 5- and 15-phenyl rings in both molecules of the asymmetric unit. The overall structure of 15-phenylheme-hHO-1 is similar to that of heme-hHO-1 except for small changes in distal residues 141–150 and in the proximal Lys18 and Lys22. In the 5-phenylhemehHO-1 structure, the phenyl-substituted heme occupies the same position as heme in the heme-HO-1 complex but the 5-phenyl substituent disrupts the rigid hydrophobic wall of residues Met34, Phe214, and residues 26–42 near the -meso carbon. The results provide independent support for an electrophilic oxidation mechanism and support a role for stereochemical control of the reaction regiospecificity.Fil: Wang, Jingling. University of California; Estados UnidosFil: Niemevz, Fernando. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Orgánica; ArgentinaFil: Lad, Latesh. University of California; Estados UnidosFil: Huang, Liusheng. University of California; Estados UnidosFil: Alvarez, Diego Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Orgánica; ArgentinaFil: Buldain, Graciela Yolanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Orgánica; ArgentinaFil: Poulos, Thomas L.. University of California; Estados UnidosFil: Ortiz de Montellano, Paul R.. University of California; Estados Unido

A virtue-based model of leadership education.

This article presents a theoretical justification and a proposal that seeks to educate university students in leadership through virtues and personal competencies. A distinction is offered between virtues and competencies without opposing them. Subsequently, a leadership education model based on virtues and personal competencies is offered. This proposal applies the Aristotelian-Thomistic tradition of education in virtues considering the contributions of psychology and leadership theory. The leadership model includes eight competencies linked to the cardinal virtues, which are grouped into three domains: understanding reality, relating to others and dedication to the task. Finally, some guidelines for the further development of assessment instruments and for leadership education of university students are offered.post-print830 K

Uso de material manipulable para favorecer el desarrollo del pensamiento algebraico en estudiantes de la Facultad de Ciencias Biológicas de la Universidad Autónoma De Nuevo León.

El objetivo general de la presente investigación consiste en determinar el impacto del uso de material manipulable, diseñado para favorecer el desarrollo del pensamiento algebraico durante el proceso de enseñanza – aprendizaje del álgebra, en el desempeño académico de la Fase 1 de los estudiantes de la UA de Matemáticas en la FCB de la UANL. La presente investigación es una investigación explicativa y evaluativa, con un diseño metodológico de tipo mixto, basado en la postura epistemológica del pragmatismo. El diseño cuasiexperimental utilizado en la investigación es llamado Diseño Anidado Concurrente de Modelo Dominante (DIAC por sus siglas en inglés), consistente en un diseño con prueba - posprueba y grupos intactos, incluyendo un grupo experimental y un grupo de control, así como una valoración cualitativa de las percepciones y actitudes de los estudiantes del grupo experimental

Mecanismos de acción de las plantas ricas en taninos sobre la población adulta de nematodos gastrointestinales de los pequeños rumiantes

Gastrointestinal nematodes (GIN) represent a major health problem worldwide in grazing sheep and goat production systems. The control of these parasites has been complicated by the emergence of nematodes which are resistant to the commercially available anthelmintics (AHs). The use of tannin rich plants (TRP), as non-conventional Ahs, represents an alternative for the control of these parasites. However, the mechanism of action of such plants against adult populations of GIN has not been determined. The objective of the study was to determine the direct and indirect effect of TRP against adult populations of GIN in small ruminants. A direct effect is considered to be any action against the biology, structure and/or ultrastructure of the nematodes which is similar to a chemical AH. The indirect effect is a modification of the immune response of the host at the level of the gastrointestinal mucosa which affects the biology of the GIN. This study is divided into two stages: First stage) Two in vivo experiments conducted in Mexico and France respectively, determined the direct and indirect effects on the biology of GIN due to the consumption of the TRP forage of tzalam (Lysiloma latisiliquum), sainfoin (Onobrychis viciifolia) as well as a tannin-rich quebracho extract (Schinopsis spp). Lambs were artificially infected with Haemonchus contortus (Mexico) or H. contortus and Trichostrongylus colubriformis (France). The consumption of tzalam affected the length and fertility of H. contortus females. Meanwhile, the quebracho extract reduced the population of H. contortus and T. colubriformis also affecting the fecundity of T. colubriformis. The sainfoin affected the fecundity of H. contortus without affecting T. colubriformis. The indirect effect was not evident. Second stage) An in vitro assay and two in vivo experiments with goats infected with H. contortus allowed to identify the effect of the consumption of TRP (tzalam or sainfoin) on the structure and ultrastructure of H. contortus. Alterations in cuticle and cephalic region were found. The aggregates in the vulva were only found in vitro. The ultrastructure of H. contortus showed a vacuolization process in the intestinal and muscular tissues of these nematodes. The lesions suggest that the compounds contained in the foliage of TRP may be involved in vital functions of H. contortus such as mobility, nutrition and possibly reproduction. This study is a contribution towards the understanding the mechanisms of AH action of the TRP against GIN