Introduction to nonlinearities, business cycles, and forecasting

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Introduction to nonlinearities, business cycles, and forecasting.

Forecasting; Business cycles;

Composing textual modelling languages in practice

This is the author's version of the work. It is posted here for your personal use. Not for redistribution. The definitive Version of Record was published in Proceedings of the 6th International Workshop on Multi-Paradigm Modeling, http://dx.doi.org/10.1145/2508443.2508449Complex systems require descriptions using multiple modelling languages, or languages able to express different concerns, like timing or data dependencies. In this paper, we propose techniques for the modular definition and composition of languages, including their abstract, concrete syntax and semantics. These techniques are based on (meta-)model templates, where interface elements and requirements for their connection can be established. We illustrate the ideas using the MetaDepth textual meta-modelling tool

Towards Enabling Mobile Domain-specific Modelling

Model-Driven Engineering (MDE) promotes an active use of models in all phases of software development. In this paradigm, the design and usage of Domain-Specific Languages (DSL) for modelling in a certain application area is frequent. While in MDE, modelling has been traditionally supported by desktop computers, in this position paper we analyse useful scenarios for modelling using mobile devices, like smartphones or tablets. Moreover, we present a working architecture and a prototype tool, called DSL-comet, which enable collaborative mobile modelling and integrate seamlessly desktop and mobile graphical modelling environments.Work supported by the Spanish Ministry of Economy and Competitivity (TIN2014-52129-R), the R&D programme of the Madrid Region (S2013/ICE-3006), and the EU commission (FP7-ICT-2013-10, #611125)

Demand for Library and Information Science professionals in Spain: Analysis of the names of job offers and tasks and skills involved

El objetivo de este estudio es profundizar en las causas de la disminución en la demanda de formación especializada en Información y Documentación a pesar del papel cada vez más destacado que posee la información y la documentación en el mercado laboral. Se recopiló una muestra de ofertas de trabajo públicas y privadas anunciadas durante 2012 y 2013 a nivel estatal, analizando la formación exigida y las tareas o competencias profesionales asociadas a las denominaciones más demandadas. Se concluye que la formación en Biblioteconomía y Documentación es demandada cuando el puesto de trabajo está vinculado al tratamiento y gestión de documentos, mientras que nuestras titulaciones no se consideran apropiadas cuando el trabajo está relacionado con la gestión de información y con las tecnologías, ámbito laboral cada vez más relevante para nuestros egresados.The aim of this study is to examine the causes of the decline in demand for specialized training in Library and Information Science despite the increasingly role of information and documentation in the labor market. A sample of public and private job offers announced during 2012 and 2013 at the state level were collected, analyzing the academic training, tasks and skills associated with the most frequent denominations. It is concluded that academic training in Library and Information Science is required when the job is linked to the treatment and management of documents, while our degrees are not considered appropriate when the work is related to information management and technology, these last jobs being more important for our graduates now and in the future

Pattern-Based Development of Domain-Specific Modelling Languages

Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. A. Pescador, A. Garmendia, E. Guerra, J. Sánchez Cuadrado and J. de Lara, "Pattern-based development of Domain-Specific Modelling Languages," Model Driven Engineering Languages and Systems (MODELS), 2015 ACM/IEEE 18th International Conference on, Ottawa, ON, 2015, pp. 166-175. doi: 10.1109/MODELS.2015.7338247Model-Driven Engineering (MDE) promotes the use of models to conduct all phases of software development in an automated way. Models are frequently defined using Domain- Specific Modelling Languages (DSMLs), which many times need to be developed for the domain at hand. However, while constructing DSMLs is a recurring activity in MDE, there is scarce support for gathering, reusing and enacting knowledge for their design and implementation. This forces the development of every new DSML to start from scratch. To alleviate this problem, we propose the construction of DSMLs and their modelling environments aided by patterns which gather knowledge of specific domains, design alternatives, concrete syntax, dynamic semantics and functionality for the modelling environment. They may have associated services, realized via components. Our approach is supported by a tool that enables the construction of DSMLs through the application of patterns, and synthesizes a graphical modelling environment according to them.Work supported by the Spanish MINECO (TIN2011-24139 and TIN2014-52129-R), the R&D programme of the Madrid Region (S2013/ICE-3006), and the EU commission (FP7-ICT-2013-10, #611125)

Comparative Exoproteome Analysis of Streptococcus suis Human Isolates

The swine pathogen Streptococcus suis is a Gram-positive bacterium which causes infections in pigs, with an impact in animal health and in the livestock industry, and it is also an important zoonotic agent. During the infection process, surface and secreted proteins are essential in the interaction between microorganisms and their hosts. Here, we report a comparative proteomic analysis of the proteins released to the extracellular milieu in six human clinical isolates belonging to the highly prevalent and virulent serotype 2. The total secreted content was precipitated and analyzed by GeLC-MS/MS. In the six strains, 144 proteins assigned to each of the categories of extracellular or surface proteins were identified, as well as 680 predicted cytoplasmic proteins, many of which are putative moonlighting proteins. Of the nine predicted signal peptide-I secreted proteins, seven had relevant antigenic potential when they were analyzed through bioinformatic analysis. This is the first work comparing the exoproteome fraction of several human isolates of this important pathogen

Democracy and the curse of natural resources

We propose a theoretical model to explain empirical regularities related to the curse of natural resources. This is an explicitly political model which emphasizes the behavior and incentives of politicians. We extend the standard voting model to give voters political control beyond the elections. This gives rise to a new restriction into our political economy model: policies should not give rise to a revolution. Our model clarifies when resource discoveries might lead to revolutions, namely, in countries with weak institutions. Natural resources may be bad for democracy by harming political turnover. Our model also suggests a non-linear dependence of human capital on natural resources. For low levels of democracy human capital depends negatively on natural resources, while for high levels of democracy the dependence is reversed. This theoretical finding is corroborated in both cross section and panel data regressions

Consensus on the Clinical Approach to Moderate-to-Severe Atopic Dermatitis in Spain: A Delphi Survey

Background. The purpose of this study was to gather information on the current assessment and management of patients with moderate-to-severe AD in routine daily practice. Methods. A cross-sectional two-round Delphi survey with the participation of dermatologists and allergologists throughout Spain was conducted. They completed a 46-item questionnaire, and consensus was defined when responses of >= 80% of participants coincided in the categories of a 5-point Likert scale for that item. Results. A total of 105 specialists (aged 40-59 years) completed the two rounds. Participants agreed regarding the consideration of AD as a multifaceted disease and the differences in clinical presentation of AD according to the patient's age. It is recommendable to perform a skin biopsy to exclude early stage T-cell cutaneous lymphoma, psoriasis, or dermatitis herpetiformis, among others (99.1%). Also, consensus was reached regarding the use of the SCORAD index to quantify the severity of the disease (86.7%), the use of wet wraps to increase the effect of topical corticosteroids (90.4%), the usefulness of proactive treatment during follow-up (85.6%) and tacrolimus ointment (91.2%) to reduce new flares, and the fact that crisaborole is not the treatment of choice for severe AD (92.4%). AD was not considered a contraindication for immunotherapy in patients with allergic respiratory diseases (92.4%). In patients with severe AD, the use of immune response modifier drugs (97.6%) or phototherapy (92.8%) does not sufficiently cover their treatment needs. Consensus was also obtained regarding the role of the new biologic drugs (93.6%) targeting cytokines involved in the Th2 inflammatory pathway (92.0%) and the potential role of dupilumab as first-line treatment (90.4%) in moderate-to-severe AD patients. Conclusion. This study contributes a reference framework to the care of AD patients. There is no diagnostic test or biomarkers to direct treatment or to assess the severity of the disease, and many therapeutic challenges remain