Pulse-like and crack-like ruptures in experiments mimicking crustal earthquakes

Theoretical studies have shown that the issue of rupture modes has important implications for fault constitutive laws, stress conditions on faults, energy partition and heat generation during earthquakes, scaling laws, and spatiotemporal complexity of fault slip. Early theoretical models treated earthquakes as crack-like ruptures, but seismic inversions indicate that earthquake ruptures may propagate in a self-healing pulse-like mode. A number of explanations for the existence of slip pulses have been proposed and continue to be vigorously debated. This study presents experimental observations of spontaneous pulse-like ruptures in a homogeneous linear-elastic setting that mimics crustal earthquakes; reveals how different rupture modes are selected based on the level of fault prestress; demonstrates that both rupture modes can transition to supershear speeds; and advocates, based on comparison with theoretical studies, the importance of velocity-weakening friction for earthquake dynamics

Stability of pulse-like earthquake ruptures

Pulse-like ruptures arise spontaneously in many elastodynamic rupture simulations and seem to be the dominant rupture mode along crustal faults. Pulse-like ruptures propagating under steady-state conditions can be efficiently analysed theoretically, but it remains unclear how they can arise and how they evolve if perturbed. Using thermal pressurisation as a representative constitutive law, we conduct elastodynamic simulations of pulse-like ruptures and determine the spatio-temporal evolution of slip, slip rate and pulse width perturbations induced by infinitesimal perturbations in background stress. These simulations indicate that steady-state pulses driven by thermal pressurisation are unstable. If the initial stress perturbation is negative, ruptures stop; conversely, if the perturbation is positive, ruptures grow and transition to either self-similar pulses (at low background stress) or expanding cracks (at elevated background stress). Based on a dynamic dislocation model, we develop an elastodynamic equation of motion for slip pulses, and demonstrate that steady-state slip pulses are unstable if their accrued slip $b$ is a decreasing function of the uniform background stress $\tau_\mathrm{b}$. This condition is satisfied by slip pulses driven by thermal pressurisation. The equation of motion also predicts quantitatively the growth rate of perturbations, and provides a generic tool to analyse the propagation of slip pulses. The unstable character of steady-state slip pulses implies that this rupture mode is a key one determining the minimum stress conditions for sustainable ruptures along faults, i.e., their ``strength''. Furthermore, slip pulse instabilities can produce a remarkable complexity of rupture dynamics, even under uniform background stress conditions and material properties

User benefits and funding strategies

The justification, economic and technological benefits of NASA Space Programs (aside from pure scientific objectives), in improving the quality of life in the United States is discussed and outlined. Specifically, a three-step, systematic method is described for selecting relevant and highly beneficial payloads and instruments for the Interim Upper Stage (IUS) that will be used with the space shuttle until the space tug becomes available. Viable Government and private industry cost-sharing strategies which would maximize the number of IUS payloads, and the benefits obtainable under a limited NASA budget were also determined. Charts are shown which list the payload instruments, and their relevance in contributing to such areas as earth resources management, agriculture, weather forecasting, and many others

Total scattering descriptions of local and cooperative distortions in the oxide spinel (Mg,Cu)Cr2O4 with dilute Jahn-Teller ions

The normal spinel oxide MgCr2O4 is cubic at room temperature while the normal spinel CuCr2O4 is tetragonal as a consequence of the Jahn-Teller nature of Cu2+ on the tetrahedral sites. Despite different end-member structures, complete solid solutions of Mg_{1-x}Cu_xCr2O4 can be prepared that display a first-order structural transition with composition x = 0.43 at room temperature. Reverse Monte Carlo analysis of total neutron scattering on data acquired between 300 K and 15 K on samples with x = 0.10, 0.20, and 0.43 provides unbiased local and average structure descriptions of the samples, including an understanding of the transition from local Jahn-Teller distortions in the cubic phase to cooperative distortions that result in a tetragonal structure. Distributions of continuous symmetry measures help to understand and distinguish distorted and undistorted coordination around the tetrahedral site in the solid solutions. Magnetic exchange bias is observed in field-cooled hysteresis loops of samples with dilute Cu2+ concentration and in samples with tetragonal--cubic phase coexistence around 300 K.Comment: 10 pages, 14 figure

Collaborative research and the co-production of knowledge for practice: an illustrative case study.

This is the final version of the article. Available from BioMed Central via the DOI in this record.BACKGROUND: In 2008, the National Institute for Health Research (NIHR) began funding a major 5-year pilot research programme of translational research in England, establishing nine 'Collaborations for Leadership in Applied Health Research and Care' (CLAHRCs). A number of evaluations were carried out to examine whether or not the various collaborations worked as intended and why. In this paper, we examine what the theory of co-production adds to understanding of processes of knowledge creation and translation we observed in one of the CLAHRCs. METHODS: A case study of a successful knowledge translation project was identified from our wider realist evaluation of the mechanisms of closer collaboration at play in the CLAHRC. In the project, a computer simulation model of an emergency pathway for acute ischaemic stroke was built to explore if and how the time between the onset and treatment of the condition could be minimised by redesigning the pathway. The aim of the case study was to improve our understanding of the nature and workings of the mechanisms of closer collaboration that were associated with the more successful projects by examining the relevance of the theory of co-production. Qualitative methods of analysis were used to explore the fit between the mechanisms of closer collaboration we observed in the realist evaluation and the principles of co-production we identified from the literature. RESULTS: We found a close fit between the nine mechanisms of closer collaboration at work in the project and the principles of co-production (active agents; equality of partners; reciprocity and mutuality; transformative; and facilitated). The successful style of collaborative working exemplified by the project was consistent with a strong form of co-production. CONCLUSIONS: In our view, the theory of co-production provides useful insights into what it is about the qualities of collaborative working that inspire the requisite mechanisms for generating knowledge that is translated into practice. The theory provides a potentially useful basis for future knowledge translation programmes and projects in applied health research in a range of contexts.We would like to thank the participants for taking part in this research and giving their time so generously and the reviewers for their helpful comments on an earlier version of the paper. This research was supported by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South-West Peninsula. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health

Universality of residence-time distributions in non-adiabatic stochastic resonance

We present mathematically rigorous expressions for the residence-time and first-passage-time distributions of a periodically forced Brownian particle in a bistable potential. For a broad range of forcing frequencies and amplitudes, the distributions are close to periodically modulated exponential ones. Remarkably, the periodic modulations are governed by universal functions, depending on a single parameter related to the forcing period. The behaviour of the distributions and their moments is analysed, in particular in the low- and high-frequency limits.Comment: 8 pages, 1 figure New version includes distinction between first-passage-time and residence-time distribution

Predicted long-term mortality reduction associated with the second round of breast screening in East Anglia

Randomized trials have demonstrated that mammographic screening can reduce breast cancer mortality. Our aim was to estimate the reduction in mortality expected from the East Anglian breast screening programme. Breast screening achieves benefit by improving cancer prognosis (reducing tumour size, nodal involvement and possibly grade) through earlier diagnosis. We compared cancer prognosis between women invited for screening and those not yet invited in East Anglia, UK, in order to predict the mortality reduction achievable by screening, independently of any reduction due to changes in treatment and underlying disease. Participants (both invited and not-yet invited) were women eligible for invitation to first and second screens and diagnosed with invasive breast cancer in 1989–96. Death rates were predicted based on the observed distribution of tumour grade, size and node status amongst 950 cancers diagnosed following first invitation, up to and including at second screen (excluding those detected at first screening), and 451 cancers presenting symptomatically in women awaiting first invitation during the staggered introduction of screening, after adjustment for lead time amongst screen detected cases. For all ages, the ratio of predicted breast cancer mortality in the invited compared with the uninvited group was 0.85 (95% CI 0.78, 0.93). It was 0.93 (0.80, 1.08) for women aged 50–54 at diagnosis and 0.81 (0.72, 0.91) for those aged 55–64. We conclude that, by 2004, the second round of screening in East Anglia should reduce mortality by around 7% in women below age 55 at diagnosis, and by around 19% in those aged 55–64. © 2001 Cancer Research Campaign http://www.bjcancer.co

Effect of component stiffness and deformation on vehicle lateral drift during braking

This article presents a simulation study into effects of compliant (flexible) components (such as the engine subframe and the lower control arm) and their deflections on the characteristics of a vehicle experiencing steering drift during straight-line braking. The vehicle front and rear suspension are modelled using multi-body dynamic analysis software. The front suspension model represents theMacPherson strut design of the vehicle and includes a rack and pinion steering system, brake system, engine subframe, and a powertrain unit. The model has been analysed under two steering control methods: fixed and free control. Suspension characteristics and the effect of deflections arising from the subframe and the lower control arm on these suspension characteristics have been analysed. The simulations confirmed that variation of component stiffness and interactions within components give rise to side-to-side deflections that could affect lateral drift during braking. It is concluded that side-to-side variation of suspension characteristics can have a detrimental effect on lateral drift during braking and that compliant components whose stiffness varies from side to side can cause different side-to-side deflections that can induce and influence variation in suspension characteristics such as toe steer angle that can lead the vehicle during braking

Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites.

BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection. It has been assumed that parasites causing relapse would be a subset of the parasites that caused the primary infection. METHODS: Paired samples were collected before initiation of antimalarial treatment and at recurrence of parasitemia from 149 patients with vivax malaria in Thailand (n=36), where reinfection could be excluded, and during field studies in Myanmar (n=75) and India (n=38). RESULTS: Combined genetic data from 2 genotyping approaches showed that novel P. vivax populations were present in the majority of patients with recurrent infection (107 [72%] of 149 patients overall [78% of patients in Thailand, 75% of patients in Myanmar {Burma}, and 63% of patients in India]). In 61% of the Thai and Burmese patients and in 55% of the Indian patients, the recurrent infections contained none of the parasite genotypes that caused the acute infection. CONCLUSIONS: The P. vivax populations emerging from hypnozoites commonly differ from the populations that caused the acute episode. Activation of heterologous hypnozoite populations is the most common cause of first relapse in patients with vivax malaria

Two types of nematicity in the phase diagram of the cuprate superconductor YBa2_2Cu3_3Oy_y

Nematicity has emerged as a key feature of cuprate superconductors, but its link to other fundamental properties such as superconductivity, charge order and the pseudogap remains unclear. Here we use measurements of transport anisotropy in YBa$_2$Cu$_3$O$_y$ to distinguish two types of nematicity. The first is associated with short-range charge-density-wave modulations in a doping region near $p = 0.12$. It is detected in the Nernst coefficient, but not in the resistivity. The second type prevails at lower doping, where there are spin modulations but no charge modulations. In this case, the onset of in-plane anisotropy - detected in both the Nernst coefficient and the resistivity - follows a line in the temperature-doping phase diagram that tracks the pseudogap energy. We discuss two possible scenarios for the latter nematicity.Comment: 8 pages and 7 figures. Main text and supplementary material now combined into single articl