This is not an apple! Benefits and challenges of applying computer vision to museum collections

The application of computer vision on museum collection data is at an experimental stage with predictions that it will grow in significance and use in the coming years. This research, based on the analysis of five case studies and semi-structured interviews with museum professionals, examined the opportunities and challenges of these technologies, the resources and funding required, and the ethical implications that arise during these initiatives. The case studies examined in this paper are drawn from: The Metropolitan Museum of Art (USA), Princeton University Art Museum (USA), Museum of Modern Art (USA), Harvard Art Museums (USA), Science Museum Group (UK). The research findings highlight the possibilities of computer vision to offer new ways to analyze, describe and present museum collections. However, their actual implementation on digital products is currently very limited due to the lack of resources and the inaccuracies created by algorithms. This research adds to the rapidly evolving field of computer vision within the museum sector and provides recommendations to operationalize the usage of these technologies, increase the transparency on their application, create ethics playbooks to manage potential bias and collaborate across the museum sector

Information-theoretic significance of the Wigner distribution

A coarse grained Wigner distribution p_{W}(x,u) obeying positivity derives out of information-theoretic considerations. Let p(x,u) be the unknown joint PDF (probability density function) on position- and momentum fluctuations x,u for a pure state particle. Suppose that the phase part Psi(x,z) of its Fourier transform F.T.[p(x,u)]=|Z(x,z)|exp[iPsi(x,z)] is constructed as a hologram. (Such a hologram is often used in heterodyne interferometry.) Consider a particle randomly illuminating this phase hologram. Let its two position coordinates be measured. Require that the measurements contain an extreme amount of Fisher information about true position, through variation of the phase function Psi(x,z). The extremum solution gives an output PDF p(x,u) that is the convolution of the Wigner p_{W}(x,u) with an instrument function defining uncertainty in either position x or momentum u. The convolution arises naturally out of the approach, and is one-dimensional, in comparison with the two-dimensional convolutions usually proposed for coarse graining purposes. The output obeys positivity, as required of a PDF, if the one-dimensional instrument function is sufficiently wide. The result holds for a large class of systems: those whose amplitudes a(x) are the same at their boundaries (Examples: states a(x) with positive parity; with periodic boundary conditions; free particle trapped in a box).Comment: pdf version has 16 pages. No figures. Accepted for publ. in PR

Parallel Microbial Ecology of Pasteuria and Nematode Species in Scottish Soils

Copyright © 2020 Orr, Neilson, Freitag, Roberts, Davies, Blok and Cock.Pasteuria spp. are endospore forming bacteria which act as natural antagonists to many of the most economically significant plant parasitic nematodes (PPNs). Highly species-specific nematode suppression may be observed in soils containing a sufficiently high density of Pasteuria spp. spores. This suppression is enacted by the bacteria via inhibition of root invasion and sterilization of the nematode host. Molecular methods for the detection of Pasteuria spp. from environmental DNA (eDNA) have been described; however, these methods are limited in both scale and in depth. We report the use of small subunit rRNA gene metabarcoding to profile Pasteuria spp. and nematode communities in parallel. We have investigated Pasteuria spp. population structure in Scottish soils using eDNA from two sources: soil extracted DNA from the second National Soil Inventory of Scotland (NSIS2); and nematode extracted DNA collected from farms in the East Scotland Farm Network (ESFN). We compared the Pasteuria spp. community culture to both nematode community structure and the physiochemical properties of soils. Our results indicate that Pasteuria spp. populations in Scottish soils are broadly dominated by two sequence variants. The first of these aligns with high identity to Pasteuria hartismeri, a species first described parasitizing Meloidogyne ardenensis, a nematode parasite of woody and perennial plants in northern Europe. The second aligns with a Pasteuria-like sequence which was first recovered from a farm near Edinburgh which was found to contain bacterial feeding nematodes and Pratylenchus spp. encumbered by Pasteuria spp. endospores. Further, soil carbon, moisture, bulk density, and pH showed a strong correlation with the Pasteuria spp. community composition. These results indicate that metabarcoding is appropriate for the sensitive, specific, and semi-quantitative profiling of Pasteuria species from eDNA.Peer reviewe

Detection of Sagittarius A* at 330 MHz with the Very Large Array

We report the detection of Sagittarius A*, the radio source associated with our Galaxy's central massive black hole, at 330 MHz with the Very Large Array. Implications for the spectrum and emission processes of Sagittarius A* are discussed and several hypothetical geometries of the central region are considered.Comment: Astrophysical Journal Letters, Accepte

Daily MODIS 500 m Reflectance Anisotropy Direct Broadcast (DB) Products for Monitoring Vegetation Phenology Dynamics

Land surface vegetation phenology is an efficient bio-indicator for monitoring ecosystem variation in response to changes in climatic factors. The primary objective of the current article is to examine the utility of the daily MODIS 500 m reflectance anisotropy direct broadcast (DB) product for monitoring the evolution of vegetation phenological trends over selected crop, orchard, and forest regions. Although numerous model-fitted satellite data have been widely used to assess the spatio-temporal distribution of land surface phenological patterns to understand phenological process and phenomena, current efforts to investigate the details of phenological trends, especially for natural phenological variations that occur on short time scales, are less well served by remote sensing challenges and lack of anisotropy correction in satellite data sources. The daily MODIS 500 m reflectance anisotropy product is employed to retrieve daily vegetation indices (VI) of a 1 year period for an almond orchard in California and for a winter wheat field in northeast China, as well as a 2 year period for a deciduous forest region in New Hampshire, USA. Compared with the ground records from these regions, the VI trajectories derived from the cloud-free and atmospherically corrected MODIS Nadir BRDF (bidirectional reflectance distribution function) adjusted reflectance (NBAR) capture not only the detailed footprint and principal attributes of the phenological events (such as flowering and blooming) but also the substantial inter-annual variability. This study demonstrates the utility of the daily 500 m MODIS reflectance anisotropy DB product to provide daily VI for monitoring and detecting changes of the natural vegetation phenology as exemplified by study regions comprising winter wheat, almond trees, and deciduous forest

On the equilibrium morphology of systems drawn from spherical collapse experiments

We present a purely theoretical study of the morphological evolution of self-gravitating systems formed through the dissipationless collapse of N-point sources. We explore the effects of resolution in mass and length on the growth of triaxial structures formed by an instability triggered by an excess of radial orbits. We point out that as resolution increases, the equilibria shift, from mildly prolate, to oblate. A number of particles N ~= 100000 or larger is required for convergence of axial aspect ratios. An upper bound for the softening, e ~ 1/256, is also identified. We then study the properties of a set of equilibria formed from scale-free cold initial mass distributions, ro ~ r^-g with 0 <= g <= 2. Oblateness is enhanced for initially more peaked structures (larger values of g). We map the run of density in space and find no evidence for a power-law inner structure when g <= 3/2 down to a mass fraction <~0.1 per cent of the total. However, when 3/2 < g <= 2, the mass profile in equilibrium is well matched by a power law of index ~g out to a mass fraction ~ 10 per cent. We interpret this in terms of less-effective violent relaxation for more peaked profiles when more phase mixing takes place at the centre. We map out the velocity field of the equilibria and note that at small radii the velocity coarse-grained distribution function (DF) is Maxwellian to a very good approximation.Comment: 16 page

Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma

Loss-of-function mutations in the RB1 tumour suppressor are key drivers in cancer, including osteosarcoma. RB1 loss-of-function compromises genome-maintenance and hence could yield vulnerability to therapeutics targeting such processes. Here we demonstrate selective hypersensitivity to clinically-approved inhibitors of Poly-ADP-Polymerase1,2 inhibitors (PARPi) in RB1-defective cancer cells, including an extended panel of osteosarcoma-derived lines. PARPi treatment results in extensive cell death in RB1-defective backgrounds and prolongs survival of mice carrying human RB1-defective osteosarcoma grafts. PARPi sensitivity is not associated with canonical homologous recombination defect (HRd) signatures that predict PARPi sensitivity in cancers with BRCA1,2 loss, but is accompanied by rapid activation of DNA replication checkpoint signalling, and active DNA replication is a prerequisite for sensitivity. Importantly, sensitivity in backgrounds with natural or engineered RB1 loss surpasses that seen in BRCA-mutated backgrounds where PARPi have established clinical benefit. Our work provides evidence that PARPi sensitivity extends beyond cancers identifiable by HRd and advocates PARP1,2 inhibition as a personalised strategy for RB1-mutated osteosarcoma and other cancers

Deformed shape invariance and exactly solvable Hamiltonians with position-dependent effective mass

Known shape-invariant potentials for the constant-mass Schrodinger equation are taken as effective potentials in a position-dependent effective mass (PDEM) one. The corresponding shape-invariance condition turns out to be deformed. Its solvability imposes the form of both the deformed superpotential and the PDEM. A lot of new exactly solvable potentials associated with a PDEM background are generated in this way. A novel and important condition restricting the existence of bound states whenever the PDEM vanishes at an end point of the interval is identified. In some cases, the bound-state spectrum results from a smooth deformation of that of the conventional shape-invariant potential used in the construction. In others, one observes a generation or suppression of bound states, depending on the mass-parameter values. The corresponding wavefunctions are given in terms of some deformed classical orthogonal polynomials.Comment: 26 pages, no figure, reduced secs. 4 and 5, final version to appear in JP

Daily MODIS 500 m Reflectance Anisotropy Direct Broadcast (DB) Products for Monitoring Vegetation Phenology Dynamics

Land surface vegetation phenology is an efficient bio-indicator for monitoring ecosystem variation in response to changes in climatic factors. The primary objective of the current article is to examine the utility of the daily MODIS 500 m reflectance anisotropy direct broadcast (DB) product for monitoring the evolution of vegetation phenological trends over selected crop, orchard, and forest regions. Although numerous model-fitted satellite data have been widely used to assess the spatio-temporal distribution of land surface phenological patterns to understand phenological process and phenomena, current efforts to investigate the details of phenological trends, especially for natural phenological variations that occur on short time scales, are less well served by remote sensing challenges and lack of anisotropy correction in satellite data sources. The daily MODIS 500 m reflectance anisotropy product is employed to retrieve daily vegetation indices (VI) of a 1 year period for an almond orchard in California and for a winter wheat field in northeast China, as well as a 2 year period for a deciduous forest region in New Hampshire, USA. Compared with the ground records from these regions, the VI trajectories derived from the cloud-free and atmospherically corrected MODIS Nadir BRDF (bidirectional reflectance distribution function) adjusted reflectance (NBAR) capture not only the detailed footprint and principal attributes of the phenological events (such as flowering and blooming) but also the substantial inter-annual variability. This study demonstrates the utility of the daily 500 m MODIS reflectance anisotropy DB product to provide daily VI for monitoring and detecting changes of the natural vegetation phenology as exemplified by study regions comprising winter wheat, almond trees, and deciduous forest

Tight informationally complete quantum measurements

We introduce a class of informationally complete positive-operator-valued measures which are, in analogy with a tight frame, "as close as possible" to orthonormal bases for the space of quantum states. These measures are distinguished by an exceptionally simple state-reconstruction formula which allows "painless" quantum state tomography. Complete sets of mutually unbiased bases and symmetric informationally complete positive-operator-valued measures are both members of this class, the latter being the unique minimal rank-one members. Recast as ensembles of pure quantum states, the rank-one members are in fact equivalent to weighted 2-designs in complex projective space. These measures are shown to be optimal for quantum cloning and linear quantum state tomography.Comment: 20 pages. Final versio