Finite Element Modeling of Ultrasonic Inspection of Weldments

High performance weldments for critical service applications require 100% inspection. Balanced against the adaptability of the ultrasonic method for automated inspection are the difficulties encountered with nonhomogeneous and anisotropic materials. This research utilizes crystals and bicrystals of nickel to model austenitic weld metal, where the anisotropy produces scattering and mode conversion, making detection and measurement of actual defects difficult. Well characterized samples of Ni are produced in a levitation zone melting facility. Crystals in excess of 25 mm diameter and length are large enough to permit ultrasonic measurements of attenuation, wave speed, and spectral content. At the same time, the experiments are duplicated as finite element models for comparison purposes. Finite element models permit easy description of boundary conditions, geometry, and loading. Direct integration of the wave equation is done with the Newmark-Beta and Wilson-Theta Methods. The usual problem with the large number of degress of freedom can be alleviated with the use of Guyan reduction. Two-dimensional comparisons showing mode conversion and a plate with a flaw are made. The continued development of this computational tool should increase understanding of quantitative ultrasonic inspection

The genomic and transcriptional landscape of primary central nervous system lymphoma

Primary lymphomas of the central nervous system (PCNSL) are mainly diffuse large B-cell lymphomas (DLBCLs) confined to the central nervous system (CNS). Molecular drivers of PCNSL have not been fully elucidated. Here, we profile and compare the whole-genome and transcriptome landscape of 51 CNS lymphomas (CNSL) to 39 follicular lymphoma and 36 DLBCL cases outside the CNS. We find recurrent mutations in JAK-STAT, NFkB, and B-cell receptor signaling pathways, including hallmark mutations in MYD88 L265P (67%) and CD79B (63%), and CDKN2A deletions (83%). PCNSLs exhibit significantly more focal deletions of HLA-D (6p21) locus as a potential mechanism of immune evasion. Mutational signatures correlating with DNA replication and mitosis are significantly enriched in PCNSL. TERT gene expression is significantly higher in PCNSL compared to activated B-cell (ABC)-DLBCL. Transcriptome analysis clearly distinguishes PCNSL and systemic DLBCL into distinct molecular subtypes. Epstein-Barr virus (EBV)+ CNSL cases lack recurrent mutational hotspots apart from IG and HLA-DRB loci. We show that PCNSL can be clearly distinguished from DLBCL, having distinct expression profiles, IG expression and translocation patterns, as well as specific combinations of genetic alterations

Coding and punching geographic and personal particulars for deaths

Part 2a: Instructions for classifying the underlying cause-of-death, ICD-10, 2006 -- Part 2b: Instructions for classifying the multiple causes of death, ICD-10, 2006. -- Part 2c: ICD-10 ACME decision tables for classifying underlying causes of death, 2006 -- Part 2e: Volume 1-ICD-10, International Statistical Classification of Diseases and Related Health Problems. Tabular list, 2006. Modified by the National Center for Health Statistics for use in the classification and analysis of medical mortality data in the U.S. -- Part 2e: Volume 3-ICD-10, International Statistical Classification of Diseases and Related Health Problems. Alphabetical index, 2006. Modified by the National Center for Health Statistics for use in the classification and analysis of medical mortality data in the U.S. -- Alphabetical index to diseases and nature of injury for use with perinatal conditions (P00-P96), 2006 -- Part 8: Geographic classification, 2003 -- Part 8a: Geographic classification (FIPS), 2004. -- Part 9: ICD-10 underlying cause-of-death lists for tabulating mortality statistics. updated Oct. 2002. -- Part 11: ICD-10 computer edits for mortality data, including separate section for fetal deaths effective 2007 -- Part 12: Computer edits for natality data effective 1993 -- Part 19: Industry and occupation coding for death certificates, 1999 -- Part 19b: Alphabetical Index of Industries and Occupations, 2003. -- Part 20: ICD-10 cause-of-death querying, 2007Initially issued annually in 6 parts: pt. 1. Coding and punching geographic and personal particulars; births, deaths, and stillbirths. - pt. 2. Cause-of-death coding. - pt. 3. Annual tabulations of deaths, births, and stillbirths. - pt. 4. Geographic code. - pt. 5. Current mortality sample; coding, punching, and tabulating monthly samples. - pt. 6. Motor-vehicle accident deaths.Also available via the World Wide Web.National Vital Statistics System Instruction manual issued in parts.Prepared by the Data Preparation Branch in collaboration with the Division of Vital Statistics

Florida /

"Sources: Base map from U.S. Geological Survey, Florida, 1967. County and place boundaries certified by local officials, January 1, 1980."Includes indexes and 6 insets