PENGARUH KOMPOSISI HERBAL DALAM MINUMAN TEH HIJAU GAMBUNG HERBAL TERHADAP HAMBATAN α-GLUKOSIDASE

The aim of this study is to make a formula of green tea that is enriched by other herbs. Green tea drinks are made using the basic ingredients of gambung (THG) green tea enriched with sapodilla leaves (Manilkara zapota (Aw) bay leaves (Syzygium polyanthum (Am), Artocarpus communis (Un) breadfruit leaves, and cinnamon leaves (Cinnamomum verum (K)). The composition of gambung herbal green tea is made by reference to the antidiabetic activity of each herb. All the samples were tested for inhibition of α-glucosidase enzymes and toxicity using the lethality test method for brine shrimp. All samples showed good inhibition of the α-glucosidase enzyme barriers of gamboeng green tea (THG) 82.05%, sapodilla leaves (Aw) 97.81%, breadfruit leaves (Un) 73.34%, bay leaves (Am) 93.80%, cinnamon leaves (K) 91.24 %. The inhibition value of α-glucoside enzymes in the formulation of gamboeng herbal green tea drinks: 96.203% (GKUn) is higher when compared to the GKAm formula (94.78%) and GKAw (62.487%)

Pregnancy and neonatal outcomes of COVID-19: The PAN-COVID study

Objective To assess perinatal outcomes for pregnancies affected by suspected or confirmed SARS-CoV-2 infection. Methods Prospective, web-based registry. Pregnant women were invited to participate if they had suspected or confirmed SARS-CoV-2 infection between 1st January 2020 and 31st March 2021 to assess the impact of infection on maternal and perinatal outcomes including miscarriage, stillbirth, fetal growth restriction, pre-term birth and transmission to the infant. Results Between April 2020 and March 2021, the study recruited 8239 participants who had suspected or confirmed SARs-CoV-2 infection episodes in pregnancy between January 2020 and March 2021. Maternal death affected 14/8197 (0.2%) participants, 176/8187 (2.2%) of participants required ventilatory support. Pre-eclampsia affected 389/8189 (4.8%) participants, eclampsia was reported in 40/ 8024 (0.5%) of all participants. Stillbirth affected 35/8187 (0.4 %) participants. In participants delivering within 2 weeks of delivery 21/2686 (0.8 %) were affected by stillbirth compared with 8/4596 (0.2 %) delivering ≥ 2 weeks after infection (95 % CI 0.3–1.0). SGA affected 744/7696 (9.3 %) of livebirths, FGR affected 360/8175 (4.4 %) of all pregnancies. Pre-term birth occurred in 922/8066 (11.5%), the majority of these were indicated pre-term births, 220/7987 (2.8%) participants experienced spontaneous pre-term births. Early neonatal deaths affected 11/8050 livebirths. Of all neonates, 80/7993 (1.0%) tested positive for SARS-CoV-2. Conclusions Infection was associated with indicated pre-term birth, most commonly for fetal compromise. The overall proportions of women affected by SGA and FGR were not higher than expected, however there was the proportion affected by stillbirth in participants delivering within 2 weeks of infection was significantly higher than those delivering ≥ 2 weeks after infection. We suggest that clinicians’ threshold for delivery should be low if there are concerns with fetal movements or fetal heart rate monitoring in the time around infection

Aktivitas Penghambatan Radikal Bebas Difenil Pikril Hidrazil (DPPH) Ekstrak Daun Macaranga magna Turrill: DPPH Free Radical Scavenger Activity of Macaranga magna Turrill Leaves Extract

Degenerative disease is a disease that has a large number of sufferers in Indonesia and throughout the world, one of the causes of many sufferers of degenerative diseases such as diabetes and cancer is the large amount of exposure to free radicals in the body as a result of an unhealthy lifestyle. Antioxidant compounds are one of the chemical compounds that can be used and utilized to inhibit the oxidation process as a result of the presence of free radicals, so that the incidence of degenerative diseases can be suppressed. In this study, the active extraction and fractionation process from Macaranga magna Turrill leaves which have antioxidant activity and can be developed as a compound inhibiting the oxidation process of free radicals using the chromatographic method, as well as testing the antioxidant activity using the free radical inhibition method 1,1-diphenyl-2- picrylhydrazyl (DPPH). Preliminary test results of antioxidant activity on the methanol extract of Macaranga magna Turrill leaves are known that this plant has potential as an antioxidant with an IC50 value of 11.13 ?g/mL, this is also supported by the test results of total flavonoids 19.47 mg QE/g extract and total phenol 37, 77 mg GAE/g extract

Pemberdayaan Kelompok Peduli Hipertensi untuk Upaya Pencegahan Hipertensi di Desa Sungai Pelang Kabupaten Ketapang Kalbar

Desa Sungai Pelang merupakan wilayah di Kecamatan Matan Hilir Selatan, Kabupaten Ketapang, Provinsi Kalimantan Barat dan berjarak sekitar 15 Km dari kota Ketapang. Dari hasil survei Community Base Diagnostic, Facility base diagnosis, dan Indept interview didapatkan prioritas masalah Kesehatan di Desa Sungai Pelang yaitu permasalahan penyakit hipertensi. Kurangnya Penerapan Germas (Gerakan Masyarakat Sehat) oleh Masyarakat, dan masih rendahnya tingkat Pendidikan Masyarakat di Desa Sungai Pelang menjadi salah satu penyebab permasalahan hipertensi yang tinggi di masyarakat. Tujuan kegiatan pengabdian ini yaitu untuk peningkatan pengetahuan kader tentang tekanan darah tinggi, mampu mempraktikkan senam lansia dan mempraktikkan penggunaan tensimeter digital. Kegiatan pengabdian dilaksanakan di Aula Desa Sungai Pelang yang dihadiri oleh masyarakat kelompok peduli hipertensi sebanyak 34 orang dengan metode ceramah, tanya jawab dan demonstrasi. Kegiatan penyuluhan dan pelatihan berlangsung dengan baik, diharapkan kegiatan penyuluhan dan pelatihan ini dapat menjadi solusi dalam upaya penurunan dan penanganan hipertensi di wilayah sasaran. Melalui pelatihan tersebut, diharapkan kegiatan pengabdian dapat dilanjutkan oleh kelompok hipertensi dengan diawasi dan dibina oleh pihak puskesmas

The Development of Augmented Reality Applications for Chemistry Learning

This chapter describes the use of Augmented Reality (AR) technology in chemistry education. The chapter begins with definition analysis, development, component, working principles, steps in making AR media, and supporting applications that are related with AR in education particularly for chemistry teaching and learning process. The proposed AR system consists of three parts: computers, Head Mounted Display (HMD), and markers that use AR toolkit working principles as follows:making AR through Vuforia setting stage, making the target management, managing assets, and running processes. Additionally, Unity application also supports in AR making. There were researches in the field of education especially in chemistry teaching and learning that had used AR technology, such as the concept of crystal structure, molecular geometry, molecular chirality, and molecular hybridization