9 research outputs found
Joseph de Maistre, nouveau mentor du prince : le dévoilement des mystÚres de la science politique
Joseph de Maistre, on lâa souvent notĂ©, nâa pas fait Ćuvre dâidĂ©ologue de la Contre-RĂ©volution ; ses Ćuvres sont des essais fragmentĂ©s, parfois inachevĂ©s, souvent publiĂ©s aprĂšs sa mort. En vingt ans, des ConsidĂ©rations aux SoirĂ©es, elles touchent Ă lâhistoire politique, Ă la controverse philosophique et religieuse sans construire une doctrine au sens oĂč nous lâentendons, ce qui est surprenant de la part du plus radical des contempteurs de la modernitĂ©. Diverses raisons ont Ă©tĂ© avancĂ©es : son ..
Etat présent de la recherche maistrienne
Darcel Jean-Louis. Etat présent de la recherche maistrienne. In: Cahiers de l'Association internationale des études francaises, 2000, n°52. pp. 75-83
Hagiographie, Imaginaire, Littérature: Mélanges en hommage à Jean-Pierre Perrot
International audienceĂ l'occasion du dĂ©part Ă la retraite du professeur Jean-Pierre Perrot, ses collĂšgues du Laboratoire LLS ont pris lâinitiative de rassembler ces MĂ©langes auxquels se sont associĂ©s de nombreux chercheurs dâautres universitĂ©s avec lesquels il a eu cĆur de travailler sur la LittĂ©rature mĂ©diĂ©vale. Ces spĂ©cialistes dâhorizons disciplinaires diffĂ©rents ont acceptĂ© de partager leurs rĂ©flexions sur des thĂšmes qui lui sont chers : la littĂ©rature, lâhagiographie et lâimaginaire. [...]SOMMAIRE : -*-Introduction / Alexandra-Flora PifarrĂ© -**- Bibliographie de Jean-Pierre Perrot -1- Fondements individuels et dĂ©stabilisation psychologique de l'identitĂ© / Jean-Marie BarthĂ©lĂ©my-2- Imaginaire, fin des temps et politique chez Campanella / Pascal Bouvier-3- L'Imaginaire des lieux. Bonnefoy, le vrai lieu et les faux semblants / Jean Burgos -4- De sources en sources : l'usage de la mĂ©taphore aquatique dans "La Disme de Penitanche" de Jehan de Journi / Chantal Connochie-Bourgne-5- La « success-story », hagiographie (protestante) des temps modernes ? / Olivier Cosma-6- Du voyage littĂ©raire au siĂšcle des LumiĂšres au voyage immobile de Xavier de Maistre / Jean-Louis Darcel-7- Les modes spĂ©cifiques de transmission du patrimoine oral : traditions et perspectives / Jean Derive-8- "Le Roman de la Rose", hymne Ă l'amour et encyclopĂ©die / Jean Dufournet-9- Saint Julien l'Hospitalier et Robert le Diable / Ălisabeth Gaucher-RĂ©mond-10- Arrabal et le Christ : vanitĂ© des vanitĂ©s / Jean-Paul Gavard-Perret -11- La faute Ă Voltaire ? Le Moyen Ăge dans l'Essai sur les mĆurs (1764) / Michael Kohlhauer -12- « Mais il set bien que maintes femes sont diable » : Ă©tude linguistique et littĂ©raire des termes dâadresse et insultes dans "Le roman de Marques de Rome" (BM Lyon, ms.867) / Dominique Lagorgette-13- ĂlĂ©ments fĂ©Ă©riques, magiques et merveilleux dans la chanson de geste Fierabras / Marc Le Person -14- La "Vie de sainte Anastasie" dans le lĂ©gendier de Florence / Anne-Françoise Leurquin-15- Ădouard Glissant : littĂ©rature antillaise et Moyen Ăge europĂ©en / Jean-Pol Madou-16- RĂȘves de flic : le commissaire Montalbano entre rĂȘveries et imaginaire / Barbara Meazzi-17- Le Sens de la rĂ©partition des saintes femmes dans un lĂ©gendier français de la fin du XIIIe siĂšcle / Magali Plattet-18- Ăchos dâApollonius de Tyr dans lâhagiographie : les lĂ©gendes de sainte Marie-Madeleine et des deux marchands / Ălisabeth Pinto-Mathie
Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data
Background:
General anaesthesia (GA) during endovascular thrombectomy has been associated with worse patient outcomes in observational studies compared with patients treated without GA. We assessed functional outcome in ischaemic stroke patients with large vessel anterior circulation occlusion undergoing endovascular thrombectomy under GA, versus thrombectomy not under GA (with or without sedation) versus standard care (ie, no thrombectomy), stratified by the use of GA versus standard care.
Methods:
For this meta-analysis, patient-level data were pooled from all patients included in randomised trials in PuMed published between Jan 1, 2010, and May 31, 2017, that compared endovascular thrombectomy predominantly done with stent retrievers with standard care in anterior circulation ischaemic stroke patients (HERMES Collaboration). The primary outcome was functional outcome assessed by ordinal analysis of the modified Rankin scale (mRS) at 90 days in the GA and non-GA subgroups of patients treated with endovascular therapy versus those patients treated with standard care, adjusted for baseline prognostic variables. To account for between-trial variance we used mixed-effects modelling with a random effect for trials incorporated in all models. Bias was assessed using the Cochrane method. The meta-analysis was prospectively designed, but not registered.
Findings:
Seven trials were identified by our search; of 1764 patients included in these trials, 871 were allocated to endovascular thrombectomy and 893 were assigned standard care. After exclusion of 74 patients (72 did not undergo the procedure and two had missing data on anaesthetic strategy), 236 (30%) of 797 patients who had endovascular procedures were treated under GA. At baseline, patients receiving GA were younger and had a shorter delay between stroke onset and randomisation but they had similar pre-treatment clinical severity compared with patients who did not have GA. Endovascular thrombectomy improved functional outcome at 3 months both in patients who had GA (adjusted common odds ratio (cOR) 1·52, 95% CI 1·09â2·11, p=0·014) and in those who did not have GA (adjusted cOR 2·33, 95% CI 1·75â3·10, p<0·0001) versus standard care. However, outcomes were significantly better for patients who did not receive GA versus those who received GA (covariate-adjusted cOR 1·53, 95% CI 1·14â2·04, p=0·0044). The risk of bias and variability between studies was assessed to be low.
Interpretation:
Worse outcomes after endovascular thrombectomy were associated with GA, after adjustment for baseline prognostic variables. These data support avoidance of GA whenever possible. The procedure did, however, remain effective versus standard care in patients treated under GA, indicating that treatment should not be withheld in those who require anaesthesia for medical reasons