21 research outputs found

    Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists

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    Summary recent studies have provided novel evidence regarding the effect of nicotine agonists on the prevention or modulation of cytokines storm and reduction of infection. In this study we tried to attempt to address these issues from a therapeutic perspective of nicotine agonists in this manner and we describe one of the most challenging theories of immunotherapy in coronavirus-19 (COVID-19). The analysis of the proposed mechanism goes beyond the physiological consequences of a way to design new strategies to provide anti-inflammatory drugs. © 2020 Elsevier Lt

    Correlation between brain cortex metabolic and perfusion functions in subjective idiopathic tinnitus

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    Objectives: Subjective tinnitus has associated with abnormal brain metabolism and perfusion found in functional imaging studies by fluorodeoxyglucose (FDG) and technetium99m (TC99m). But there is no study evaluating the association of brain metabolism and perfusion abnormalities in a group of these subjects. The aim of this study was to investigate if there is any significant correlation between the brain perfusion and metabolism abnormalities in subjects with tinnitus. Materials and Methods: In this cross-sectional study, 52 patients were undergone TC99m-ECD single photon emission computerized tomography (SPECT) scan and F18-FDG positron emission tomography (PET). The results of PET and SPECT scanning were fused with MRI to accurate anatomical localization of abnormalities. The analysis was performed using Kendal's correlation, t-test and chi square. Results: Assessing these 52 tinnitus subjects (containing 42 males 76.4%) showed that a significant correlation was found between the brain metabolic function and perfusion (p value 0.001)

    An Initial Exploration of Engineering Student Perceptions of COVID’s Impact on Connectedness, Learning, and STEM Identity

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    This paper studied the development of STEM identity for freshman students in Engineering. An Urban Research University received a 5-year S-STEM award in fall 2018. So far, two cohorts of scholars have received the scholarship as well as academic support, mentoring support, and customized advising from faculty and upper level peers. The objective of this project is to help underrepresented and talented students in engineering to pursue an undergraduate degree. A Multi-Layered Mentoring(MLM) Program was established, and several interviews were conducted with scholarship recipients. The qualitative and qualitative analysis of the student success shows an improvement in GPA of students in the program as compared to the rest of the school. The students not only received financial help through the program based on their unmet needs, they are were placed in an engineering learning community (ELC). The participants in ELC and MLM programs agreed to participate in research studies to assess their success. This NSF funded program also helped freshman students be involved in a hands-on Design Innovations class where they learned design process and human centered design. The students were surveyed on a regular basis to identify their needs and were approached by faculty advisor as well as their mentors to trouble shoot their concerns and help them with both social and academic aspects of their concerns. The first cohort joined the program in AY 2019-2020, as freshmen. This cohort had experienced a full semester of in-person engagement before the COVID-19 hit in the middle of the second semester of their freshman year. We have researched the impact of the pandemic on their academic progress, sense of belonging, and STEM identity. The second cohort joined the program in AY 2020-2021. They have not had the chance to experience the campus life and their perspective of college life is very different than the first cohort. The STEM identity was one of the success indicators for freshman students who entered the university in one of the most difficult and un-usual circumstances under the COVID-19 pandemic

    Survival of COVID-19 patients requires precise immune regulation: The hypothetical immunoprotective role of nicotinic agonists

    Get PDF
    Summary recent studies have provided novel evidence regarding the effect of nicotine agonists on the prevention or modulation of cytokines storm and reduction of infection. In this study we tried to attempt to address these issues from a therapeutic perspective of nicotine agonists in this manner and we describe one of the most challenging theories of immunotherapy in coronavirus-19 (COVID-19). The analysis of the proposed mechanism goes beyond the physiological consequences of a way to design new strategies to provide anti-inflammatory drugs. © 2020 Elsevier Lt

    Launching the urban STEM collaboratory

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    The Urban STEM Collaboratory is a tri-institution collaboration of University of Memphis (UofM), University of Colorado Denver (CU Denver), and Indiana University Purdue University Indianapolis (IUPUI). Each of the three partner universities is embedded in a large city, and serves similar student populations, i.e. students who tend to be first generation, minorities, and/or commuters. These universities encounter similar challenges in first-year retention and graduation rates, especially in the STEM disciplines. As they strive to improve the first year engineering and/or mathematics student experience at their campuses, they have engaged in different approaches; including Peer Led Team Learning (PLTL), formation of an Engineering Learning Community (ELC), and engaging students in outreach as STEM Ambassadors. Incorporating these individual strengths with new activities that will be shared across institutions, the team is currently embarking on a multi-year research project to uncover how students develop STEM identity in an urban context, identify interventions that support this development, and determine the impact that STEM identity has on student success. Through the support of an NSF S-STEM grant, the three universities are also providing scholarships to students engaged in the project. Here, we share the initial efforts of our tri-campus interaction and collaboration, our overarching goals, our systems of recruiting students, and our initial collection of preliminary data and findings for Year 1

    Launching the urban STEM collaboratory

    No full text
    The Urban STEM Collaboratory is a tri-institution collaboration of University of Memphis (UofM), University of Colorado Denver (CU Denver), and Indiana University Purdue University Indianapolis (IUPUI). Each of the three partner universities is embedded in a large city, and serves similar student populations, i.e. students who tend to be first generation, minorities, and/or commuters. These universities encounter similar challenges in first-year retention and graduation rates, especially in the STEM disciplines. As they strive to improve the first year engineering and/or mathematics student experience at their campuses, they have engaged in different approaches; including Peer Led Team Learning (PLTL), formation of an Engineering Learning Community (ELC), and engaging students in outreach as STEM Ambassadors. Incorporating these individual strengths with new activities that will be shared across institutions, the team is currently embarking on a multi-year research project to uncover how students develop STEM identity in an urban context, identify interventions that support this development, and determine the impact that STEM identity has on student success. Through the support of an NSF S-STEM grant, the three universities are also providing scholarships to students engaged in the project. Here, we share the initial efforts of our tri-campus interaction and collaboration, our overarching goals, our systems of recruiting students, and our initial collection of preliminary data and findings for Year 1
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