5,091 research outputs found

    Prospero Fontana tra Genova e Bologna (1528-1539). Proposte e documenti per la sua prima attività

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    Contributi Tatiana Kustodieva: Novita su dipinti di Raffaello Botticinie Rosso Fiorentino conservati all’Ermitage - Giulia Daniele: Prospero Fontana tra Genova e Bologna (1528-1539). Proposte e documenti per la sua prima attività - Claudia Terribile: Tre dipinti di Paolo Veronese per Matteo Calergi e una nuova traccia per El Greco a Venezia - Lorenzo Finocchi Ghersi: Trittico veneziano attorno alla Famiglia di Dario: Veronese, Vittoria, de’ Grigi - Irina Artemieva, Elena Bortnikova: Lettera da Oranienbaum: Aliense, Ludovico Carracci, Mazzoni - Davide Dossi: Alfred Moir, Pasquale Ottino e la Maddalena di Minneapolis - Giuseppe Dardanello: Filippo e Francesco Juvarra, disegni per argenti e oreficerie romane (I) – Denis Ton: Tennis, Tiepolo e tornado. Fra Sebald e Walcott, appunti sulla recente fortuna tiepolesca. Attualità Stéphane Loire, Peintures italiennes di XVIIIe siècle du Musée du Louvre. Catalogue raisonné, avec un préface de Sébastien Allard (Giuseppe Pavanello) - Antonio Natali, Il museo. Pagine da una stagione agli Uffizi (Andrea Baldinotti

    Le lettere di Pietro Veri a Virginio Orsini sul cantiere di Montegiordano

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    Si pubblica in trascrizione parte di un carteggio inedito tra l'artista e architetto Pietro Veri e il suo committente Virginio Orsini, duca di Bracciano, relativo ai lavori di pittura e ristrutturazione del palazzo romano di Montegiordano

    Tunisian Women\u27s Activism after the January 14 Revolution: Looking within and towards the Other Side of the Mediterranean

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    Tunisia is widely considered to be the country in which the current round of major upheavals in North Africa and the Middle East began. This paper explores the most prominent instances of women’s activism which have taken place in Tunisia in the time which has followed the revolution of 2011. Through analysis of the principal literature related to the subject and the information gathered as a result of fieldwork conducted in the capital city of Tunis in February 2013, the paper examines the most significant transformations which have arisen from the active participation of women in the uprising. The involvement of women in the demand for changes in Tunisia questions whether women’s political engagement can be seen as an essential asset within Tunisian civil society organizations, and, if it can, this prompts us to go on to consider the implications of this also for the role of international aid funding (with specific reference to the European Union). Overall, the Tunisian uprising can be represented in terms of a remarkable case in which civil society, including the women’s organizations, has played a useful and effective role at a political and social level, ensuring the emergence of a feasible alternative pathway

    Rural electrification in central america and east africa, two case studies of sustainable microgrids

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    This paper deals with the electrification of rural villages in developing countries using Sustainable Energy Systems. The rural electrification feasibility study is done using Hybrid Optimization Model for Electric Renewable PRO (HOMER PRO). The HOMER PRO energy modelling software is an optimization software improved by U.S. National Renewable Energy Laboratory. It helps in designing, comparing and optimizing the design of power generation technologies. In this paper, two rural electrification case studies are modelled and analysed using HOMER PRO. Technical and economic evaluation criteria are applied to study the feasibility of a micro-hydro plant in El Díptamo (Honduras), and a hybrid plant composed of photovoltaic module arrays, Diesel generators, and flow batteries, in a small island on Victoria Lake. For both cases, we show the results of the studies of the daily and yearly loads, of the resources available in the area and the economic evaluation of the chosen plants configuration

    Non-canonical proteolytic activation of human prothrombin by subtilisin from Bacillus subtilis may shift the procoagulant\ue2\u80\u93anticoagulant equilibrium toward thrombosis

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    Blood coagulation is a finely regulated physiological process culminating with the factor Xa (FXa)-mediated conversion of the prothrombin (ProT) zymogen to active -thrombin (T). In the prothrombinase complex on the platelet surface, FXa cleaves ProT at Arg-271, generating the inactive precursor pre-thrombin-2 (Pre2), which is further attacked at Arg-320 \u2013Ile-321 to yield mature T. Whereas the mechanism of physiological ProT activation has been elucidated in great detail, little is known about the role of bacterial proteases, possibly released in the bloodstream during infection, in inducing blood coagulation by direct proteolytic ProT activation. This knowledge gap is particularly concerning, as bacterial infections are frequently complicated by severe coagulopathies. Here, we show that addition of subtilisin (50 nM to 2 M), a serine protease secreted by the non-pathogenic bacterium Bacillus subtilis, induces plasma clotting by proteolytically converting ProT into active Pre2, a nicked Pre2 derivative with a single cleaved Ala-470 \u2013Asn-471 bond. Notably, we found that this non-canonical cleavage at Ala-470 \u2013Asn-471 is instrumental for the onset of catalysis in Pre2, which was, however, reduced about 100 \u2013200-fold compared with T. Of note, Pre2 could generate fibrin clots from fibrinogen, either in solution or in blood plasma, and could aggregate human platelets, either isolated or in whole blood. Our findings demonstrate that alternative cleavage of ProT by proteases, even by those secreted by non-virulent bacteria such as B. subtilis, can shift the delicate procoagulant\u2013anticoagulant equilibrium toward thrombosis

    Porous metallosilicates for heterogeneous, liquid-phase catalysis: perspectives and pertaining challenges

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    Porous silicates containing dilute amounts of tri-, tetraand penta-valent metal sites, such as TS-1, Sn-β and Fe- ZSM-5, have recently emerged as state of the art catalysts for a variety of sustainable chemical transformations. In contrast with their aluminosilicate cousins, which are widely employed throughout the refinery industry for gas-phase catalytic transformations, such metallosilicates have exhibited unprecedented levels of performance for a variety of liquidphase catalytic processes, including the conversion of biomass to chemicals, and sustainable oxidation technologies with H2O2. However, despite their unique levels of performance for these new types of chemical transformations, increased utilization of these promising materials is complicated by several factors. For example, their utilization in a liquid, and often polar, medium hinders process intensification (scaleup,catalyst deactivation). Moreover, such materials do not generally exhibit the active-site homogeneity of conventional aluminosilicates, and they typically possess a wide variety of active-site ensembles, only some of which may be directly involved in the catalytic chemistry of interest. Consequently,mechanistic understanding of these catalysts remains relatively low, and competitive reactions are commonly observed. Accordingly, unified approaches towards developing more active, selective and stable porous metallosilicates have not yet been achieved. Drawing on some of the most recent literature in the field, the purpose of this mini review is both to highlight the breakthroughs made with regard to the use of porous metallosilicates as heterogeneous catalysts for liquidphase processing, and to highlight the pertaining challenges that we, and others, aim to overcome during the forthcoming years

    W+W−W^+W^- production at NNLO+PS with MiNNLOPS_{\rm PS}

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    We consider W+W−W^+W^- production in hadronic collisions and present the computation of next-to-next-to-leading order accurate predictions consistently matched to parton showers (NNLO+PS) using the MiNNLOPS_{\rm PS} method. Spin correlations, interferences and off-shell effects are included by calculating the full process pp→e+νeμ−νˉμpp \to e^+\nu_e \mu^-\bar{\nu}_\mu. This is the first NNLO+PS calculation for W+W−W^+W^- production that does not require an a-posteriori multi-differential reweighting. The evaluation time of the two-loop contribution has been reduced by more than one order of magnitude through a four-dimensional cubic spline interpolation. We find good agreement with the inclusive and fiducial cross sections measured by ATLAS and CMS. Both NNLO corrections and matching to parton showers are important for an accurate simulation of the W+W−W^+W^- signal, and their matching provides the best description of fully exclusive W+W−W^+W^- events to date.Comment: 45 pages, 12 figures, 2 table

    Advancing MiNNLOPS_{\rm PS} to diboson processes: ZγZ\gamma production at NNLO+PS

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    We consider ZγZ \gamma production in hadronic collisions and present the first computation of next-to-next-to-leading order accurate predictions consistently matched to parton showers (NNLO+PS). Spin correlations, interferences and off-shell effects are included by calculating the full process pp→ℓ+ℓ−γpp\to\ell^+\ell^-\gamma. We extend the recently developed MiNNLOPS_{\rm PS} method to genuine 2→22\to 2 hard scattering processes at the LHC, which paves the way for NNLO+PS simulations of all diboson processes. This is the first 2→22\to2 NNLO+PS calculation that does not require an a-posteriori multi-differential reweighting. We find that both NNLO corrections and matching to parton showers are crucial for an accurate simulation of the ZγZ \gamma process. Our predictions are in very good agreement with recent ATLAS data.Comment: 42 pages, 10 figures, 2 table

    THE IMPORTANCE OF BEING MEAN

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    Many historical loci can be obtained through approaches that differ from classic methods built on their own pure description as loci. Aim of this work is to show how various algebraic curves can be obtained as the locus for particular midpoints, and how the consideration of the latter can give rise to a succession of homotheties, namely, contractions or dilations, of the original curve. What is important to underline is that points generating a locus possess the particular property of being midpoints of other pairs of points, or segments, stemming from a particular configurations of points and lines. This is illustrated here, by various examples
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