89 research outputs found
Investigating last food mile deliveries: A case study approach to identify needs of food delivery demand
© 2017 Drawing on the results of a survey carried out in Cagliari (Italy), the paper provides an analysis of the characteristics of food deliveries in urban areas aimed at understanding the needs and expectations of receivers of last mile deliveries of fresh products. In fact, exploring the needs of potential users - who are directly responsible for the success of the scheme - and the characteristics of logistics flows they generate/attract in the city centre is a necessary prerequisite for implementing city logistics measures. The study considers independent retailers within the hotel, restaurants and catering (Ho.Re.Ca.) sector. Based on the delivery characteristics, a classification of commercial activities related to the food chain is provided. The analysis has been developed by means of Multiple Correspondence Analysis (MCA) and Cluster analysis. The suitability of city logistics measures to the last food mile is also discussed
About the Efficacy of Virtual and Remote Laboratories in STEM Education in Secondary School: A Second-Order Systematic Review
Online laboratories brought new opportunities for instruction. In this work, a secondorder systematic review about the efficacy of virtual and remote labs on learning in high school STEM education is presented. Nine systematic review and a meta-analysis were included. A descriptive summary (qualitative and quantitative) of their findings is provided. On average, online laboratories support learning to an extent comparable to that observed in real labs; their effect is even more positive when they are integrated into more traditional teaching practice (e.g., as pre-lab practice sessions before the hands-on experiments) and when they are supported by adequate teacher feedback. Content knowledge is the learning outcome most often assessed; while practical and inquiry skills related to scientific reasoning are investigated less frequently. The results are promising for instructional design and for the future research, despite the data variability and some methodological limitations of individual studies (lack of relevant quantitative data, such as effect sizes and moderator analysis). Further experimental research is required to estimate the effect of online labs on different learning outcomes and to better understand the moderating role of some variables related to interventions and students
When gravity meets philosophy again: the Gravitas project
Gravity is, by far, one of the scientific themes that have most piqued the
curiosity of scientists and philosophers over the centuries. The history of
science tells us that when the creative effort of physicists and philosophers
to solve the main puzzles of the understanding of our universe met, a new
conceptual revolution has started. However, since Einstein's relativistic
theories and the subsequent advent of quantum mechanics, physicists and
philosophers have taken different paths, both kidnapped by the intrinsic
conceptual and mathematical difficulties inherited by their studies. Is it
possible to restore a unitary vision of knowledge, overcoming the
scientific-humanistic dichotomy that has established itself over time? The
answer is certainly not trivial, but we can start from school to experience a
new vision of a unified knowledge. From this need, the Gravitas project has
born. Gravitas is a multidisciplinary outreach and educational program devoted
to high school students (17-19 years old) that mixes contemporary physics and
the philosophy of science. Coordinated by the Cagliari Section of the National
Institute of Nuclear Physics, in Italy, Gravitas has started on December 2021
with an unconventional online format: two researchers coming from different
fields of research meet a moderator and informally discuss about gravity and
related phenomena. The public can chat and indirectly interact with them during
the YouTube live. The project involved about 250 students from 16 high schools
in Sardinia, Italy. Students should also create posts thought for social media
whose content is based on the seminars they attended during the project. We
present the project and discuss its possible outcomings concerning the
introduction of a multidisciplinary approach in teaching physics, philosophy,
and the history of contemporary physics in high schools.Comment: To appear in Proceedings of ICHEP 2022 Conference, 6 pages, 8
figures. An extended version of the abstract appears in the pape
I laboratori online per l’apprendimento scientifico: sintesi delle evidenze
In this study, the results of a second-order systematic review concerning the impact of online (virtual and remote) laboratories on learning in STEM education for secondary school students are discussed. After the selection phase, based on eligibility criteria, ten systematic reviews and meta-analyses were included. The comparative analysis of data provides useful information for the instructional design of laboratory activities mediated by technologies and for the future research. In particular, results showed that online laboratories generally support learning outcomes comparable to those in traditional laboratories; and they suggest that some factors (e.g. teacher training; coherence of goals, laboratory activities, assessment; teacher feedback; integration of online-traditional laboratory activities) can maximize their efficacy. In addition, methodological limitations of current literature suggest the need for further primary studies with a more rigorous design.In questo lavoro, si presentano e discutono i risultati di una revisione sistematica di secondo ordine sull’efficacia dei laboratori online (virtuali e remoti) per il miglioramento degli apprendimenti nell’educazione STEM, in contesti di scuola secondaria. Al termine della fase di selezione, sulla base dei criteri di eleggibilità adottati, sono stati inclusi dieci studi secondari (revisioni sistematiche e meta-analisi). L’analisi comparativa di questi ultimi fornisce indicazioni utili per la progettazione didattica di attività laboratoriali mediate da tecnologie e per gli sviluppi futuri della ricerca. I risultati consentono di affermare che tendenzialmente i laboratori online permettono agli studenti di raggiungere risultati di apprendimento comparabili a quelli dei laboratori tradizionali e suggeriscono la rilevanza di determinati fattori (tra cui, la formazione degli insegnanti; la coerenza tra obiettivi, strategia laboratoriale e valutazione; il feedback dell’insegnante; l’integrazione tra attività laboratoriali online e in presenza) al fine di massimizzarne l’efficacia. Allo stesso tempo, si rilevano alcuni limiti metodologici della letteratura esistente, tali per cui ulteriori studi e un maggior rigore nel design di questi appaiono auspicabili
Multi-stakeholder collaboration in urban freight consolidation schemes: Drivers and barriers to implementation
© 2018 The Author(s). Published by VGTU Press. Due to the motivations of climate change, the health impacts of poor air quality, and the importance of cities for economic growth, transport policy at all levels of governance places emphasis on reducing and managing urban traffic and congestion. Whilst the majority of urban traffic is created by personal travel, freight vehicles make a relatively large contribution per vehicle to congestion, pollution and severe accidents. The European Commission (EC 2011) estimates that 6% of all EU transport carbon emissions are from urban freight. For these reasons, a well-structured portfolio of measures and policies oriented towards more sustainable and efficient management of supply chain activities carried out in urban areas is needed, in order to reduce negative externalities related to urban mobility and improve economic performance. In recent years, there has been enthusiasm amongst commentators that shared-resource economic models can both create new commercial opportunities and address policy problems, including in the transport sector. Within the city logistics subsector, this new model is exemplified by the emergence of Urban freight Consolidation Centres (UCCs). UCCs replace multiple ‘last-mile’ delivery movements, many of which involving small consignments, by a common receiving point (the consolidation centre), normally on the periphery of a city, with the final part of the delivery being shared by the consignments in a small freight vehicle. Such arrangements can represent a good compromise between the needs of city centre businesses and their customers on the one hand (i.e. high availability of a range of goods) and local and global sustainability objectives on the other. At the same time, by sharing logistics facilities and delivery vehicles, UCCs offer added-value services to both urban economic actors, such as retailers, and network logistics providers. However, UCCs add to the complexity of logistics chains, requiring additional contracts, communications and movement stages. These arrangements also introduce additional actors within the supply of delivery services, notably local authorities present as promoters and funders, rather than simply as regulators, companies specialised in the UCC operation, and companies, which provide specialist technologies, such as electric delivery vehicles. UCCs therefore also represent an example of multi-stakeholder collaboration. Drawing on the results of a 2013 survey in Bristol (United Kingdom) and a further survey carried out in 2015 in Cagliari (Italy), the present paper will provide an in-depth comparison of the differences in the perceptions of urban freight users and stakeholders towards UCCs. Retailers involved in the survey carried out in Bristol showed high satisfaction with the delivery service provided by the UCC. Different topic areas (e.g. timeliness, reliability, safety) are examined through analyses of both qualitative and quantitative data. The survey carried out in Cagliari investigated the inclination of potential users to join a UCC scheme. The comparison between the two cities considers factors such as the nature of business holding (e.g. SME versus multiple retailers), operational practices (e.g. pattern of deliveries) and operating subsector (e.g. food versus no food). An analysis on the barriers to the implementation of UCCs in Bristol and in Cagliari is provided at the end of the paper
Effects of Metabolic Syndrome on Cognitive Performance of Adults During Exercise
The metabolic syndrome (MS) has been associated with poor performances in multiple cognitive domains, as processing speed, visuo-spatial abilities, and executive functioning. Exercise is a critical factor for MS people’s vulnerability to cognitive dysfunction, because this may be beneficial to reduce cognitive impairment, but limited physical activity and impaired cerebral blood flow in response to exercise have been reported by individuals suffering from MS. Using an attentional interference test, the Bivalent Shape Task (BST), and metaboreflex, we analyzed cognitive performance and cerebral oxygenation (COX) in 13 MS people (five women), and 14 normal age-matched control (CTL, six women). Five different sessions were administered to all participants, each lasting 12 min: control exercise recovery (CER), post-exercise muscle ischemia (PEMI) to activate the metaboreflex, CER + BST, PEMI + BST, and BST alone. During each session, cognitive performance was assessed by means of response times and response accuracy with which participants make the decision and COX was evaluated by near infrared spectroscopy with sensors applied in the forehead. Compared to CTL, MS group performed significantly worse in all sessions (F = 4.18; p = 0.05; ES = 0.13): their poorest performance was observed in the BST alone session. Moreover, when BST was added to PEMI, individuals of the CTL group significantly increased their COX compared to baseline (103.46 ± 3.14%), whereas this capacity was impaired in MS people (102.37 ± 2.46%). It was concluded that: (1) MS affects cognitive performance; (2) people with MS were able to enhance COX during exercise, but they impair their COX when an attentional interference task was added
Affective variables and cognitive performances during exercise in a group of adults with type 2 diabetes mellitus
Previous research has documented that type 2 diabetes mellitus (T2DM) is associated with cognitive impairment. Psychological variables were repeatedly investigated to understand why T2DM patients are poorly active, despite standards of medical care recommends performing aerobic and resistance exercise regularly and reducing the amount of time spent sitting. This exploratory study aims to investigate how affective variables as thoughts, feelings, and individuals’ stage of exercise adoption can modulate low cognitive performances during an experimental procedure based on exercise. The Exercise Thoughts Questionnaire (ETQ), Exercise-Induced Feeling Scale (EFI), and Physical Activity Stage of Change were administered to a sample of 12 T2DM patients. The Bivalent Shape Task (BST) alone (BST), BST with exercise [control exercise recovery (CER) + BST], and BST with metaboreflex [post-exercise muscle ischemia (PEMI) + BST] were used as mental task, and response time to congruent, incongruent, and neutral stimuli was recorded. Concomitant cerebral oxygenation (COX) was evaluated by near-infrared spectroscopy (NIRS). As expected, T2DM patients performed significantly better when the stimulus was presented in congruent trials (followed by neutral and incongruent). In the CER + BST session, T2DM patients showed longer reaction time to incongruent trials than in the PEMI + BST and BST alone sessions. Positive feelings toward exercise seem to modulate cognitive performances in high challenging task only if T2DM patients were conscious to play exercise. These results could provide some insights for health intervention targeting exercise for patients with T2DM in order to enhance cognitive performances
Specific immunoassays confirm association of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> with type-1 but not type-2 diabetes mellitus
Background
Mycobacterium avium subspecies paratuberculosis (MAP) is a versatile pathogen with a broad host range. Its association with type-1 diabetes mellitus (T1DM) has been recently proposed. Rapid identification of infectious agents such as MAP in diabetic patients at the level of clinics might be helpful in deciphering the role of chronic bacterial infection in the development of autoimmune diseases such as T1DM.
Methodology/Principal Findings
We describe use of an ELISA method to identify live circulating MAP through the detection of a cell envelope protein, MptD by a specific M13 phage – fMptD. We also used another ELISA format to detect immune response to MptD peptide. Both the methods were tested with blood plasma obtained from T1DM, type-2 diabetes (T2DM) patients and non-diabetic controls. Our results demonstrate MptD and fMptD ELISA assays to be accurate and sensitive to detect MAP bacilli in a large fraction (47.3%) of T1DM patients as compared to non-diabetic controls (12.6%) and those with confirmed T2DM (7.7%). Comparative analysis of ELISA assays performed here with 3 other MAP antigen preparations, namely HbHA, Gsd and whole cell MAP lysates confirmed comparable sensitivity of the MptD peptide and the fMptD based ELISA assays. Moreover, we were successful in demonstrating positive bacterial culture in two of the clinical specimen derived from T1DM patients.
Conclusions and Significance
The MptD peptide/fMptD based ELISA or similar tests could be suggested as rapid and specific field level diagnostic tests for the identification of MAP in diabetic patients and for finding the explanations towards the occurrence of type-1 or type-2 diabetes in the light of an active infectious trigger
Prevalence of IgG antibodies against Borrelia Burgdorferi s.l. and Ehrlichia Phagocytophila in sera of patients presenting symptoms of Lyme disease in a central region of Italy.
The aim of this study was to evaluate the prevalence (seroprevalence) of antibodies against Borrelia burgdorferi and Ehrlichia phagocytophila among patients resident in Lazio, a region of central Italy. Of a sample of 1,050 patients, which presented clinical manifestations related to Lyme disease, 34 (3.2%) were Borrelia-seropositive (Lyme index value ≥ 1.2). The sera of 25 out of the 34 patients that were Borrelia-positive were also analysed for the presence of antibodies against E. phagocytophila and 3 (12%) were found Ehrlichia-positive (titres >1:64). No Ehrlichia-positive samples were found among sera of 250 Borrelia-negative patients. Since both B. burgdorferi s.l. and Ehrlichia species share the same tick vector ( Ixodes ricinus), our results indicate that concurrent transmission of these microbial pathogens might have been occurred among the patients included in this study
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