Through the looking glass: the framing of law through popular imagination

It has been 150 years since the first publication of Lewis Carroll’s acclaimed children’s fiction Alice’s Adventures in Wonderland,2 and it remains a book that is appreciated widely across culture for its unique representation of the world. Indeed, the enduring quality of both Alice’s Adventures in Wonderland and Through the Looking Glass,3 is evident in the way they have inspired creations of art, theatrical performances,4 judicial decision-making,5 cinematic portrayals,6 videogame plot development,7 and of course, the desire for adventure

British government and popular understanding of inflation in the mid-1970s

In Britain in the 1970s inflation rose to historically unprecedented peace-time levels, and became the central issue of economic policy-making. We know a great deal about the elite policy debates on the significance of this inflation, and the arguments about how to reduce it, but we know far less about how inflation was understood by the population at large, and how those understandings were shaped. This article explores the evidence on popular understanding, especially analysing the material gathered by the Counter-Inflation Publicity Unit, created in the summer of 1975. Along with other evidence, this material is used to explore how far the Labour government's economic propaganda can be said to have influenced popular opinion on both the significance and causes of inflation. The evidence supports the argument that the belief that trade unions were the main culprit for inflation was reinforced and entrenched by this propaganda, with important unintended consequences for the arguments about policy that followed the ‘Winter of Discontent’ of 1978/9

Patients at high risk of tuberculosis recurrence

Recurrent tuberculosis (TB) continues to be a significant problem and is an important indicator of the effectiveness of TB control. Recurrence can occur by relapse or exogenous reinfection. Recurrence of TB is still a major problem in high-burden countries, where there is lack of resources and no special attention is being given to this issue. The rate of recurrence is highly variable and has been estimated to range from 4.9% to 47%. This variability is related to differences in regional epidemiology of recurrence and differences in the definitions used by the TB control programs. In addition to treatment failure from noncompliance, there are several key host factors that are associated with high rates of recurrence. The widely recognized host factors independent of treatment program that predispose to TB recurrence include gender differences, malnutrition; comorbidities such as diabetes, renal failure, and systemic diseases, especially immunosuppressive states such as human immunodeficiency virus; substance abuse; and environmental exposures such as silicosis. With improved understanding of the human genome, proteome, and metabolome, additional host-specific factors that predispose to recurrence are being identified. Information on temporal and geographical trends of TB cases as well as studies with whole-genome sequencing might provide further information to enable us to fully understand TB recurrence and discriminate between reactivation and new infection. The recently launched World Health Organization End TB Strategy emphasizes the importance of integrated, patient-centered TB care. Continued improvement in diagnosis, treatment approaches, and an understanding of host-specific factors are needed to fully understand the clinical epidemiological and social determinants of TB recurrence