Environmental Ethics And Sustainable Territorial Development. An Analysis From The Speciesism Category

The article proposes ways to relate discussions held at the field of Environmental Ethics with analysis about the Sustainable Territorial Development. For this, a summary discussion of this field is presented, emphasizing the category of Speciesism and the problem of moral consideration of animals. This approach aims to show the heuristic potential that this category have to analyse patterns of territorial development supported by livestock. From an empirical point of view, the article analyses data from the meat industry in Santa Catarina, from which the notion of Intensive Speciesism Regions (ISR) is outlined. They constitute territories that show Speciesism disproportionately intense in their development patterns, result of a socio-political, economic and symbolic process that combines radical moral disregard of animals with unrighteousness among humans.194395

Temperatura E Substrato Na Germinação De Sementes De Plukenetia Volubilis L.

The objective of this work was to evaluate the effect of temperature and substrate on the germination of P. volubilis seeds. Seeds harvested from 25 matrix plants were submitted, in two studies, to conditions of (i) sowing in rolled paper towel at the temperatures of 10, 15, 20, 25, 30, 35, 40, and 45 °C, for the evaluation of germination, first count of germination, germination speed index and mean time for germination, and (ii) sowing in the substrates paper towel, sand, Bioplant®, Bioplant® and micron, superfine, fine, medium and coarse vermiculite. The same evaluations mentioned in the first study were conducted at the temperature of 30 oC, as well as plant growth. The treatment replicates were distributed in a completely randomized block design and the effects of temperature were compared by polynomial regression analysis. The substrates were compared by the Scott-Knott test at 0.05 probability level. The data show that the ideal range of temperature for the germination of P. volubilis is between 25 and 30 °C. The temperature of 20 °C is the minimum for germination and those above 35 °C are lethal to these seeds. The most favorable substrate for P. volubilis seed germination is micron or fine vermiculite. © 2016, Departamento de Engenharia Agricola - UFCG/Cnpq. All rights reserved.20111031103

Interaction protocols for cross-organisational workflows

Workflow technologies are widely used in industry and commerce to assist in the specification, execution and completion of well defined processes within organisations. As industrial and commercial relations have evolved, based on advances on information and communications technologies, cross-organisational workflow integration has become an important issue. Since organisations can have very different workflows, the creation of compatible workflows so that organisations can collaborate and/or carry out mutual transactions automatically in an integrated fashion can be a very complex and time consuming process. As a consequence, the development of technologies to support the creation and execution of compatible workflows is a most relevant issue. In the present article we introduce the JamSession coordination platform as a tool to implement cross-organisational workflow integration. JamSession is declarative and based on algebraic specification methods, and therefore workflow integration implemented using this platform can profit from formal behavioural analysis, based on which desired features and properties can be verified and/or obtained

Humificação de lodos orgânicos

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Clinical Treatment Of Resistant Epilepsy

[No abstract available]46435135

Cholesterol-functionalized carvedilol-loaded PLGA nanoparticles: anti-inflammatory, antioxidant, and antitumor effects

The inflammation has been identified as factor of tumor progression, which has increased the interest and use of molecules with anti-inflammatory and antioxidant activities in the cancer treatment. In this study, the antioxidant, anti-inflammatory, and antitumor potentials of carvedilol was explored in a different approach. The cholesterol (CHO) was investigated as facilitated agent in the action of carvedilol-loaded nanoparticles. Different formulations exhibited spherical and stable nanoparticle with mean diameter size < 250 nm. The cholesterol changed the copolymer-drug interactions and the encapsulation efficiency. The in vitro cancer study was performed using murine colorectal cancer cell line (CT-26) to observe the cell viability and apoptosis on MTS assay and flow cytometry, respectively. The experiments have demonstrated that cholesterol improved the performance of drug-loaded nanoparticles, which was much better than free drug. The in vivo inflammation peritonitis model revealed that carvedilol-loaded nanoparticles increased the level of glutathione and leukocyte migration mainly when the functionalized drug-loaded nanoparticles were tested, in a lower dose than the free drug. As hypothesized, the experimental data suggest that cholesterol-functionalized carvedilol-loaded PLGA nanoparticles can be a novel and promising approach in the inflammation-induced cancer therapy since showed anti-inflammatory, antioxidant, and antitumor effects.Graphical abstractRadiolog

Apathy and functional disability in behavioral variant frontotemporal dementia

Background Behavioral variant frontotemporal dementia (bvFTD) has profound consequences on patients and their families. In this multicenter study, we investigated the contribution of cognitive and neuropsychiatric factors to everyday function at different levels of overall functional impairment. Methods In a retrospective cross-sectional study, 109 patients with bvFTD from 4 specialist frontotemporal dementia centers (Australia, England, India, and Brazil) were included. The measures administered evaluated everyday function (Disability Assessment for Dementia [DAD]), dementia staging (Clinical Dementia Rating [CDR]), general cognition (Addenbrooke’s Cognitive Examination–revised [ACE-R]), and neuropsychiatric symptoms (Neuropsychiatric Inventory [NPI]). Patients were then subdivided according to functional impairment on the DAD into mild, moderate, severe, and very severe subgroups. Three separate multiple linear regression analyses were run, where (1) total DAD, (2) basic activities of daily living (BADL), and (3) instrumental activities of daily living (IADL) scores were dependent variables; ACE-R total score and selected NPI domains (agitation/aggression, euphoria, apathy, disinhibition, irritability, aberrant motor behavior) were used as independent variables. Age, sex, education, and country of origin were controlled for in the analyses. Results Cognitive deficits were similar across the mild, moderate, and severe subgroups but significantly worse in the very severe subgroup. NPI domain scores (agitation/aggression, euphoria, apathy, disinhibition, irritability, aberrant motor behavior) did not differ across the DAD subgroups. In the multiple regression analyses, a model including ACE-R and NPI apathy explained 32.5% of the variance for total DAD scores. For IADL, 35.6% of the variance was explained by the ACE-R only. No model emerged for BADL scores. Conclusions Cognitive deficits and apathy are key contributors to functional disability in bvFTD but factors underlying impairment in BADLs remain unclear. Treatments targeting reduction of disability need to address apathy and cognitive impairment to ensure greater efficacy, especially in regards to IADLs