3,615 research outputs found
Assessment team report on flight-critical systems research at NASA Langley Research Center
The quality, coverage, and distribution of effort of the flight-critical systems research program at NASA Langley Research Center was assessed. Within the scope of the Assessment Team's review, the research program was found to be very sound. All tasks under the current research program were at least partially addressing the industry needs. General recommendations made were to expand the program resources to provide additional coverage of high priority industry needs, including operations and maintenance, and to focus the program on an actual hardware and software system that is under development
Current investment practices of New England life insurance companies
Thesis (M.B.A.)--Boston Universit
The role of periarticular soft tissues in persistent motion loss in a rat model of posttraumatic elbow contracture
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Evolutionary Signatures In The Formation Of Low-Mass Protostars. II. Toward Reconciling Models And Observations
A long-standing problem in low-mass star formation is the "luminosity problem," whereby protostars are underluminous compared to the accretion luminosity expected both from theoretical collapse calculations and arguments based on the minimum accretion rate necessary to form a star within the embedded phase duration. Motivated by this luminosity problem, we present a set of evolutionary models describing the collapse of low-mass, dense cores into protostars. We use as our starting point the evolutionary model following the inside-out collapse of a singular isothermal sphere as presented by Young & Evans. We calculate the radiative transfer of the collapsing core throughout the full duration of the collapse in two dimensions. From the resulting spectral energy distributions, we calculate standard observational signatures (L(bol), T(bol), L(bol)/L(smm)) to directly compare to observations. We incorporate several modifications and additions to the original Young & Evans model in an effort to better match observations with model predictions; we include (1) the opacity from scattering in the radiative transfer, (2) a circumstellar disk directly in the two-dimensional radiative transfer, (3) a two-dimensional envelope structure, taking into account the effects of rotation, (4) mass-loss and the opening of outflow cavities, and (5) a simple treatment of episodic mass accretion. We find that scattering, two-dimensional geometry, mass-loss, and outflow cavities all affect the model predictions, as expected, but none resolve the luminosity problem. On the other hand, we find that a cycle of episodic mass accretion similar to that predicted by recent theoretical work can resolve this problem and bring the model predictions into better agreement with observations. Standard assumptions about the interplay between mass accretion and mass loss in our model give star formation efficiencies consistent with recent observations that compare the core mass function and stellar initial mass function. Finally, the combination of outflow cavities and episodic mass accretion reduces the connection between observational class and physical stage to the point where neither of the two commonly used observational signatures (T(bol) and L(bol)/L(smm)) can be considered reliable indicators of physical stage.NASA 1224608, 1288664, 1288658, RSA 1377304, NNX 07-AJ72GNSF AST0607793UT Austin University Continuing FellowshipAstronom
Low-speed wind-tunnel tests of an advanced eight-bladed propeller
As part of a research program on advanced turboprop aircraft aerodynamics, a low-speed wind-tunnel investigation was conducted to document the basic performance and force and moment characteristics of an advanced eight-bladed propeller. The results show that in addition to the normal force and pitching moment produced by the propeller/nacelle combination at angle of attack, a significant side force and yawing moment are also produced. Furthermore, it is shown that for test conditions wherein compressibility effects can be ignored, accurate simulation of propeller performance and flow fields can be achieved by matching the nondimensional power loading of the model propeller to that of the full-scale propeller
MF890
Edward P. Call & James R. Dunham, A guide to successful AI, Kansas State University, September 1992
Nature’s Machinery, Repurposed: Expanding the Repertoire of Iron-Dependent Oxygenases
Iron is an especially important redox-active cofactor in biology because of its ability to mediate reactions with atmospheric O₂. Iron-dependent oxygenases exploit this earth-abundant transition metal for the insertion of oxygen atoms into organic compounds. Throughout the astounding diversity of transformations catalyzed by these enzymes, the protein framework directs reactive intermediates toward the precise formation of products, which, in many cases, necessitates the cleavage of strong C–H bonds. In recent years, members of several iron-dependent oxygenase families have been engineered for new-to-nature transformations that offer advantages over conventional synthetic methods. In this Perspective, we first explore what is known about the reactivity of heme-dependent cytochrome P450 oxygenases and nonheme iron-dependent oxygenases bearing the 2-His-1-carboxylate facial triad by reviewing mechanistic studies with an emphasis on how the protein scaffold maximizes the catalytic potential of the iron-heme and iron cofactors. We then review how these cofactors have been repurposed for abiological transformations by engineering the protein frameworks of these enzymes. Finally, we discuss contemporary challenges associated with engineering these platforms and comment on their roles in biocatalysis moving forward
Nature’s Machinery, Repurposed: Expanding the Repertoire of Iron-Dependent Oxygenases
Iron is an especially important redox-active cofactor in biology because of its ability to mediate reactions with atmospheric O₂. Iron-dependent oxygenases exploit this earth-abundant transition metal for the insertion of oxygen atoms into organic compounds. Throughout the astounding diversity of transformations catalyzed by these enzymes, the protein framework directs reactive intermediates toward the precise formation of products, which, in many cases, necessitates the cleavage of strong C–H bonds. In recent years, members of several iron-dependent oxygenase families have been engineered for new-to-nature transformations that offer advantages over conventional synthetic methods. In this Perspective, we first explore what is known about the reactivity of heme-dependent cytochrome P450 oxygenases and nonheme iron-dependent oxygenases bearing the 2-His-1-carboxylate facial triad by reviewing mechanistic studies with an emphasis on how the protein scaffold maximizes the catalytic potential of the iron-heme and iron cofactors. We then review how these cofactors have been repurposed for abiological transformations by engineering the protein frameworks of these enzymes. Finally, we discuss contemporary challenges associated with engineering these platforms and comment on their roles in biocatalysis moving forward
Neighborhood Differences in Attitudes toward Policing: Evidence for a Mixed-Strategy Model of Policing in a Multi-Ethnic Setting
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