15 research outputs found
The partitioning of poleward energy transport response between the atmosphere and Ekman flux to prescribed surface forcing in a simplified GCM
Recent studies have indicated that ocean circulation damps the atmospheric energy transport response to hemispherically differential energy perturbations, thereby muting the shifts of the Inter-Tropical Convergence Zone (ITCZ). Here, we focus on the potential role of Ekman heat transport in modulating this atmospheric response. An idealized representation of Ekman-driven heat transport (FE) is included in an aquaplanet slab ocean coupled to a gray radiation atmospheric model. We first alter the strength of FE in the control climate by tuning the gross stability of the Ekman layer SE. For a wide range of FE, the total poleward transport of energy remains nearly unchanged, but the ocean transports an increasing share for larger SE. The control climate is then perturbed by adding surface cooling in the Southern Hemisphere and warming in the Northern Hemisphere. The Ekman coupling damps the atmospheric energy transport response, as in previous coupled model experiments with full ocean dynamics. The ratio of the changes in Ekman to atmospheric energy transport is determined by the ratio of the gross stability in the Ekman layer to the atmosphere in the control climate, and is insensitive to the amplitude and location of forcing. We find that an unrealistically large SE is needed to reproduce the ratio of the changes in cross-equatorial oceanic to atmospheric energy transport in fully coupled models. The limited damping effect of Ekman transport highlights the need to examine the roles of deep circulation and subtropical gyres, as well as ocean heat uptake processes
Paracrine cyclooxygenase-2 activity by macrophages drives colorectal adenoma progression in the Apc Min/+ mouse model of intestinal tumorigenesis
Genetic deletion or pharmacological inhibition of cyclooxygenase (COX)-2 abrogates intestinal adenoma development at early stages of colorectal carcinogenesis. COX-2 is localised to stromal cells (predominantly macrophages) in human and mouse intestinal adenomas. Therefore, we tested the hypothesis that paracrine Cox-2-mediated signalling from macrophages drives adenoma growth and progression in vivo in the ApcMin/+ mouse model of intestinal tumorigenesis. Using a transgenic C57Bl/6 mouse model of Cox-2 over-expression driven by the chicken lysozyme locus (cLys-Cox-2), which directs integration site-independent, copy number-dependent transgene expression restricted to macrophages, we demonstrated that stromal macrophage Cox-2 in colorectal (but not small intestinal) adenomas from cLys-Cox-2 x ApcMin/+ mice was associated with significantly increased tumour size (Pâ=â0.025) and multiplicity (Pâ=â0.025), compared with control ApcMin/+ mice. Transgenic macrophage Cox-2 expression was associated with increased dysplasia, epithelial cell Cox-2 expression and submucosal tumour invasion, as well as increased nuclear ÎČ-catenin translocation in dysplastic epithelial cells. In vitro studies confirmed that paracrine macrophage Cox-2 signalling drives catenin-related transcription in intestinal epithelial cells. Paracrine macrophage Cox-2 activity drives growth and progression of ApcMin/+ mouse colonic adenomas, linked to increased epithelial cell ÎČ-catenin dysregulation. Stromal cell (macrophage) gene regulation and signalling represent valid targets for chemoprevention of colorectal cancer
X-Shooting ULLYSES: Massive stars at low metallicity: I. Project description
Observations of individual massive stars, super-luminous supernovae, gamma-ray bursts, and gravitational wave events involving spectacular black hole mergers indicate that the low-metallicity Universe is fundamentally different from our own Galaxy. Many transient phenomena will remain enigmatic until we achieve a firm understanding of the physics and evolution of massive stars at low metallicity (Z). The Hubble Space Telescope has devoted 500 orbits to observing âŒ250 massive stars at low Z in the ultraviolet (UV) with the COS and STIS spectrographs under the ULLYSES programme. The complementary X-Shooting ULLYSES (XShootU) project provides an enhanced legacy value with high-quality optical and near-infrared spectra obtained with the wide-wavelength coverage X-shooter spectrograph at ESOa's Very Large Telescope. We present an overview of the XShootU project, showing that combining ULLYSES UV and XShootU optical spectra is critical for the uniform determination of stellar parameters such as effective temperature, surface gravity, luminosity, and abundances, as well as wind properties such as mass-loss rates as a function of Z. As uncertainties in stellar and wind parameters percolate into many adjacent areas of astrophysics, the data and modelling of the XShootU project is expected to be a game changer for our physical understanding of massive stars at low Z. To be able to confidently interpret James Webb Space Telescope spectra of the first stellar generations, the individual spectra of low-Z stars need to be understood, which is exactly where XShootU can deliver
No signature of the orbital motion of a putative 70 solar mass black hole in LB-1
Liu et al. (2019) recently reported the detection of a 68 [+11/-13] solar mass (Msun) black hole (BH) paired with an 8.2 [+0.9/-1.2] Msun B-type sub-giant star in the 78.9-day spectroscopic binary system LB-1. Such a black hole is over twice as massive as any other known stellar- mass black hole with non-compact companions2 and its mass approaches those that result from BH-BH coalescences that are detected by gravitational wave interferometers. Its presence in a solar-like metallicity environment challenges conventional theories of massive binary evolution, stellar winds and core-collapse supernovae, so that more exotic scenarios seem to be needed to explain the existence and properties of LB-1. Here, we show that the observational diagnostics used to derive the BH mass results from the orbital motion of the B-type star, not that of the BH. As a consequence, no evidence for a massive BH remains in the data, therefore solving the existing tension with formation models of such a massive BH at solar metallicity and with theories of massive star evolution in general
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The curious nature of the hemispheric symmetry of the Earthâs water and energy balances
This paper presents new estimates of the hemispheric
energy balance based on an assembly of radiative flux
and ocean heat data. Further, it provides an overview of recent simulations with fully coupled climate models to investigate
the role of its representation in causing tropical precipitation
biases. The energy balance portrayed here features a small
hemispheric imbalance with slightly more energy being
absorbed by the Southern hemisphere. This yields a net transport
of heat towards the NH composing of a northward crossequatorial
heat transport by the oceans and a southward heat
flow in the atmosphere. The turbulent fluxes and hemispheric
precipitation balance to about 3 Wmâ2 with slightly larger
total accumulation occurring in the NH. CloudSat data indicate
more frequent precipitation in the SH implying more
intense precipitation in the NH. Fully coupled climate model
simulations show that reducing hemispheric energy balance
biases does little to reduce existing biases in tropical
precipitation