Nutrition, lifestyle and colorectal cancer incidence: a prospective investigation of 10 998 vegetarians and non-vegetarians in the United Kingdom

In a cohort of 10998 men and women, 95 incident cases of colorectal cancer were recorded after 17 years. Risk increased in association with smoking, alcohol, and white bread consumption, and decreased with frequent consumption of fruit. The relative risk in vegetarians compared with nonvegetarians was 0.85 (95% CI: 0.55-1.32)

Growth rate, health and welfare in a dairy herd with natural suckling until 6–8 weeks of age: a case report

Over a period of two years, growth rate and health were measured for dairy calves allowed to suckle their mothers up to 6–8 weeks of age. Thirty-one calves were weighted weekly, and the mean daily growth rate was 1.2 ± 0.03 kg from birth up to 13 weeks of age. Illness in calves and young stock was not observed. In the cows, the mean incidences of ketosis, displaced abomasum, puerperal paresis, mastitis, teat injury and retained placenta were 0, 0, 8, 22, 1 and 1%, respectively, during a 6-year period. The mean daily gain of 56 growing bulls was 1.4 kg when slaughtered at 15 months of age, which is higher than the mean daily gain of 0.95 kg in the population. Probiotics, hormones and vaccines were not used, and antibiotics were only used for treating illness. The present study indicates many advantages and few problems when dairy calves are penned together with the cows and allowed natural feeding up to 6–8 weeks of age. This production system was easy to manage, preferred by the farmer, and may satisfy the public concern regarding the practice of immediate separation of cow and calf in commercial milk production

Experimental demonstration of a universally valid error-disturbance uncertainty relation in spin-measurements

The uncertainty principle generally prohibits determination of certain pairs of quantum mechanical observables with arbitrary precision and forms the basis of indeterminacy in quantum mechanics. It was Heisenberg who used the famous gamma-ray microscope thought experiment to illustrate this indeterminacy. A lower bound was set for the product of the measurement error of an observable and the disturbance caused by the measurement. Later on, the uncertainty relation was reformulated in terms of standard deviations, which focuses solely on indeterminacy of predictions and neglects unavoidable recoil in measuring devices. A correct formulation of the error-disturbance relation, taking recoil into account, is essential for a deeper understanding of the uncertainty principle. However, the validity of Heisenberg's original error-disturbance uncertainty relation is justifed only under limited circumstances. Another error-disturbance relation, derived by rigorous and general theoretical treatments of quantum measurements, is supposed to be universally valid. Here, we report a neutron optical experiment that records the error of a spin-component measurement as well as the disturbance caused on another spin-component measurement. The results confirm that both error and disturbance completely obey the new, more general relation but violate the old one in a wide range of an experimental parameter.Comment: 11 pages, 5 figures, Nature Physics (in press

Unitary and Non-Unitary Matrices as a Source of Different Bases of Operators Acting on Hilbert Spaces

Columns of d^2 x N matrices are shown to create different sets of N operators acting on $d$-dimensional Hilbert space. This construction corresponds to a formalism of the star-product of operator symbols. The known bases are shown to be partial cases of generic formulas derived by using d^2 x N matrices as a source for constructing arbitrary bases. The known examples of the SIC-POVM, MUBs, and the phase-space description of qubit states are considered from the viewpoint of the developed unified approach. Star-product schemes are classified with respect to associated d^2 x N matrices. In particular, unitary matrices correspond to self-dual schemes. Such self-dual star-product schemes are shown to be determined by dequantizers which do not form POVM.Comment: 12 pages, 1 figure, 1 table, to appear in Journal of Russian Laser Researc

Radiation-hypersensitive cancer patients do not manifest protein expression abnormalities in components of the nonhomologous end-joining (NHEJ) pathway

Radiation therapy (RT) is utilised for the treatment of around half of all oncology patients during the course of their illness. Despite great clinical progress in the rational deployment of RT, the underlying molecular basis for its efficacy and toxicity are currently imperfectly understood. In this study, we took a biochemical approach to evaluate the potential role of key ionising radiation repair proteins in the treatment outcomes of patients with severe acute or late RT side effects. Lymphoblastoid cell lines were established from blood samples from 36 radiosensitive cases and a number of controls (the latter had had RT but did not develop significant toxicity). The expression level and migration of key proteins from the nonhomologous end-joining (NHEJ) pathway was evaluated by Western blot analysis on cases and controls. We did not observe any abnormalities in expression level or migration pattern of the following NHEJ proteins in radiosensitive cancer cases: Ku70, Ku80, XRCC4, DNA Ligase IV. These important negative results provide evidence that mutations that affect protein expression of these NHEJ components are unlikely to underlie clinical radiation sensitivity

Risk factors for suicide in Bali: a psychological autopsy study

<p>Abstract</p> <p>Background</p> <p>The suicide rate in Bali has significantly increased in recent years. However, to date, there have been no case-control studies investigating risk factors for suicide.</p> <p>Methods</p> <p>A psychological autopsy study was conducted comparing 60 suicide cases and 120 living controls matched in age, sex, and area of residence.</p> <p>Results</p> <p>Multiple logistic regression analysis identified the following risk factors for suicide: at least one diagnosis of axis-I mental disorder (OR: 14.84 CI: 6.12 - 35.94); low level of religious involvement (OR: 7.24 CI: 2.28 - 22.95); and severe interpersonal problems (OR: 3.86 CI: 1.36 - 11.01). Forty-eight (80.0%) of the suicide cases were diagnosed with mental disorders; however, only 16.7% visited a primary care health professional and none received psychiatric treatment during the 1 month prior to death.</p> <p>Conclusion</p> <p>Clinical, religious, and psychosocial factors were associated with suicide. These results highlight the significance of early recognition and treatment of mental disorders, religious activities, and interpersonal problem-solving strategies for suicide prevention in Bali.</p

Coastline changes and sedimentation related with the opening of an artificial channel: the Valo Grande Delta, SE Brazil

The role played by human activity in coastline changes indicates a general tendency of retreating coasts, especially deltaic environments, as a result of the recent trend of sea level rise as well as the blockage of the transfer of sediments towards the coast, especially due to the construction of dams. This is particularly important in deltaic environments which have been suffering a dramatic loss of area in the last decades. In contrast, in this paper, we report the origin and evolution of an anthropogenic delta, the Valo Grande delta, on the south-eastern Brazilian coast, whose origin is related to the opening of an artificial channel and the diversion of the main flow of the Ribeira de Iguape River. The methodology included the analysis of coastline changes, bathy metry and coring, which were used to determine the sedimentation rates and grain-size changes over time. The results allowed us to recognize the different facies of the anthropogenic delta and establish its lateral and vertical depositional trends. Despite not being very frequent, anthropogenic deltas represent a favorable environment for the record of natural and anthropogenic changes in historical times and, thus, deserve more attention from researchers of different subjects.Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [06/04344-2]info:eu-repo/semantics/publishedVersio

Coevolution of dispersal in a parasitoid-host system

Interspecific interactions and the evolution of dispersal are both of interest when considering the potential impact of habitat fragmentation on community ecology, but the interaction between these processes is not well studied. We address this by considering the coevolution of dispersal strategies in a host-parasitoid system. An individual-based host-parasitoid metapopulation model was constructed for a patchy environment, allowing for evolution in dispersal rates of both species. Highly rarefied environments with few suitable patches selected against dispersal in both species, as did relatively static environments. Provided that parasitoids persist, all parameter values studied led to stable equilibria in dispersal rates for both species. There was a tendency towards higher dispersal rates in parasitoids due to the asymmetric relationships of the two species to the patches: vacant patches are most valuable for hosts, but unsuitable for parasitoids, which require an established host population to reproduce. High host dispersal rate was favoured by high host population growth rate, and in the parasitoid by high growth rates in both species