FORMULACIÓN DE UNA COMPOTA DE GUAYABA (Psidium guajava) ENRIQUECIDA CON HARINA GELATINIZADA DE QUINUA (Chenopodium quinoa)

La presente investigación tuvo como objetivo evaluar alternativas de formulación y preparación de compotas a base de guayaba (Psidium guajava) y de harina gelatinizada de quinua (Chenopodium quinoa), que garanticen aceptabilidad y adecuadas propiedades nutricionales para la población infantil; con el enriquecimiento de la quinua como fuente de proteínas para combatir la inseguridad alimentaria y la desnutrición infantil. La evaluación se realizó sobre tres formulaciones con diferentes proporciones de frutas y harina de quinua, con un proceso de elaboración común y que fueron sometidas a una evaluación sensorial. A la formulación de mejor aceptación se le realizaron ensayos fisicoquímicos y microbiológicos, para comprobar el cumplimiento de requisitos de calidad e inocuidad para este tipo de alimento. Como resultado se obtuvo que la formulación con un 71,71 % de guayaba y 7,97 % de harina gelatinizada de quinua es la de mayor aceptación y que la compota obtenida cumple los requisitos de calidad e inocuidad según las normas de referencias. Se concluye que este producto posee una composición que garantiza los requerimientos nutricionales de los niños entre seis y 24 meses de edad y puede ser competitiva en el mercado peruano.Tesi

Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent). Conclusion Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified