4,484 research outputs found

    Estimating preferences for controlling beach erosion in Sicily

    Get PDF
    This study applied discrete-choice experiments to estimate preferences for a program aimed at reducing the retreatment of the sandy beach at "Lido di Noto", a renowned Sicilian bathing resort close to Noto (Italy). Econometric analysis of data was based on Multinomial Logit (MNL), Latent Class (LC) and Mixed Logit (MXL) models. Findings shown that users appreciated the advancement of the current coastline through nourishment, and negatively perceived the construction of emerged sea barriers. MXL and LC models revealed that preferences were heterogeneous

    Pharmacokinetics and antinociceptive effects of tramadol and its metabolite O-desmethyltramadol following intravenous administration in sheep

    Get PDF
    Although sheep are widely used as an experimental model for various surgical procedures there is a paucity of data on the pharmacokinetics and efficacy of analgesic drugs in this species. The aims of this study were to investigate the pharmacokinetics of intravenously (IV) administered tramadol and its active metabolite O-desmethyltramadol (M1) and to assess the mechanical antinociceptive effects in sheep. In a prospective, randomized, blinded study, six healthy adult sheep were given 4 and 6\u2009mg/kg tramadol and saline IV in a cross-over design with a 2-week wash-out period. At predetermined time points blood samples were collected and physiological parameters and mechanical nociceptive threshold (MNT) values were recorded. The analytical determination of tramadol and M1 was performed using high performance liquid chromatography. Pharmacokinetic parameters fitted a two- and a non-compartmental model for tramadol and M1, respectively. Normally distributed data were analysed by a repeated mixed linear model. Plasma concentration vs. time profiles of tramadol and M1 were similar after the two doses. Tramadol and M1 plasma levels decreased rapidly in the systemic circulation, with both undetectable after 6\u2009h following drug administration. Physiological parameters did not differ between groups; MNT values were not statistically significant between groups at any time point. It was concluded that although tramadol and M1 concentrations in plasma were above the human minimum analgesic concentration after both treatments, no mechanical antinociceptive effects of tramadol were reported. Further studies are warranted to assess the analgesic efficacy of tramadol in sheep

    1-hypergroups of small sizes

    Get PDF
    In this paper, we show a new construction of hypergroups that, under appropriate conditions, are complete hypergroups or non-complete 1-hypergroups. Furthermore, we classify the 1-hypergroups of size 5 and 6 based on the partition induced by the fundamental relation \u3b2. Many of these hypergroups can be obtained using the aforesaid hypergroup construction

    Assessing the hidden impacts of hypothetical eruption events at Mount Etna

    Get PDF
    Abstract We estimate how the value and the spatial distribution of carbon storage, water yield and wild pollination services are expected to change with potential expansion of lava flow inundation at Mount Etna volcano (Sicily, Italy). We rely on a hazard map lava by flow inundation to simulate a set of three future land use/land cover (LU/LC) scenarios related to different hazard levels with a specific probability of occurrence. Our assessment used the Integrated Valuation of Environmental Services and Tradeoffs (InVEST) tool and GIS spatial analysis and indicates that changes in the delivery of all three ecosystem services are biophysically and economically sizeable. The variation between scenarios demonstrates that the carbon storage and wild pollination services will decrease because of the loss of woods and natural habitats. In contrast, the water yield capacity will increase for the creation of new naked land surfaces characterised by high permeability values. In the worst-case scenario, we estimate a loss of 17% and 10% for carbon storage and wild pollination services respectively, and an increase of approximately 10% for water yield

    Effects of atomic diffraction on the Collective Atomic Recoil Laser

    Full text link
    We formulate a wave atom optics theory of the Collective Atomic Recoil Laser, where the atomic center-of-mass motion is treated quantum mechanically. By comparing the predictions of this theory with those of the ray atom optics theory, which treats the center-of-mass motion classically, we show that for the case of a far off-resonant pump laser the ray optics model fails to predict the linear response of the CARL when the temperature is of the order of the recoil temperature or less. This is due to the fact that in theis temperature regime one can no longer ignore the effects of matter-wave diffraction on the atomic center-of-mass motion.Comment: plain tex, 10 pages, 10 figure

    Dietary intake and macrovascular disease in a Japanese-Brazilian population: a cross-sectional study

    Get PDF
    OBJETIVO: Descrever o hábito alimentar de nipo-brasileiros com e sem doença macrovascular (DMV). MÉTODOS: Definiu-se DMV, para 1.165 nipo-brasileiros, a partir de escores atribuídos ao histórico de saúde, eletrocardiograma e valores do índice tornozelo-braquial. Determinou-se o consumo alimentar habitual por meio de Questionário de Frequência do Consumo de Alimentos. RESULTADOS: A porcentagem de casos confirmados com DMV foi de 3,2%, sendo semelhante entre os sexos. Observou-se, de forma estatisticamente significante, maior frequência de indivíduos com DMV (confirmados ou suspeitos) entre aqueles de primeira geração, com idade > 60 anos, tabagistas, com hipertensão arterial, hipertrigliceridemia e diabetes. Nipo-brasileiros com DMV (confirmados ou suspeitos) apresentaram menor perímetro do quadril e maior idade, pressão arterial sistólica, triglicérides, glicemia, consumo de alimentos fonte de ferro e menor fonte de fibras de grãos. Encontrou-se diferença estatisticamente significante apenas para o consumo de gordura saturada (análise bruta: segundo terço versus primeiro terço). CONCLUSÕES: programas de educação nutricional devem ser incentivados neste grupo com alta prevalência de doenças crônicas não transmissíveis.OBJECTIVE: To describe the food intake of Japanese-Brazilians with and without macrovascular disease (MVD). METHODS: MVD was defined, for 1,165 Japanese-Brazilians, by scores attributed to the health historical, electrocardiogram and ankle-brachial index values. The usual dietary intake was determined using a food frequency questionnaire. RESULTS: The MVD prevalence was of 3.2%, being similar among genders. Statistically higher frequencies of individuals with MVD were observed among those of first generation, with age > 60 years, tobacco user, with hypertension, hypertriglyceridemia and diabetes. Subjects with MVD were older, with smaller hip circumference, and higher systolic blood pressure levels, triglycerides and glycemia concentration; they informed higher consumption of iron source food and smaller of grains fibers. Statistically significant difference was found to saturated fat (crude analysis: second tercile versus first tercile). CONCLUSIONS: Programs of nutritional education should be stimulated in this group with high prevalence of non-communicable chronic diseases.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

    INTEGRAL high energy monitoring of the X-ray burster KS 1741-293

    Full text link
    KS 1741-293, discovered in 1989 by the X-ray camera TTM in the Kvant module of the Mir space station and identified as an X-ray burster, has not been detected in the hard X band until the advent of the INTEGRAL observatory. Moreover this source has been recently object of scientific discussion, being also associated to a nearby extended radio source that in principle could be the supernova remnant produced by the accretion induced collapse in the binary system. Our long term monitoring with INTEGRAL, covering the period from February 2003 to May 2005, confirms that KS 1741-293 is transient in soft and hard X band. When the source is active, from a simultaneous JEM-X and IBIS data analysis, we provide a wide band spectrum from 5 to 100 keV, that can be fit by a two component model, a multiple blackbody for the soft emission and a Comptonized or a cut-off power law model for the hard component. Finally, by the detection of two X-ray bursters with JEM-X, we confirm the bursting nature of KS 1741-293, including this source in the class of the hard tailed X-ray bursters.Comment: 7 pages, accepted for publication on MNRA
    • …
    corecore