7,559 research outputs found
The Pillars of Creation revisited with MUSE: gas kinematics and high-mass stellar feedback traced by optical spectroscopy
This article has been accepted for publication in Monthly Notices of the Royal Astronomical Society. © 2015 The Authors. Published by Oxford University Press on behalf of the Royal Astronomical Society.Integral field unit (IFU) data of the iconic Pillars of Creation in M16 are presented. The ionization structure of the pillars was studied in great detail over almost the entire visible wavelength range, and maps of the relevant physical parameters, e.g. extinction, electron density, electron temperature, line-of-sight velocity of the ionized and neutral gas are shown. In agreement with previous authors, we find that the pillar tips are being ionized and photoevaporated by the massive members of the nearby cluster NGC 6611. They display a stratified ionization structure where the emission lines peak in a descending order according to their ionization energies. The IFU data allowed us to analyse the kinematics of the photoevaporative flow in terms of the stratified ionization structure, and we find that, in agreement with simulations, the photoevaporative flow is traced by a blueshift in the position-velocity profile. The gas kinematics and ionization structure have allowed us to produce a sketch of the 3D geometry of the Pillars, positioning the pillars with respect to the ionizing cluster stars. We use a novel method to detect a previously unknown bipolar outflow at the tip of the middle pillar and suggest that it has an embedded protostar as its driving source. Furthermore we identify a candidate outflow in the leftmost pillar. With the derived physical parameters and ionic abundances, we estimate a mass-loss rate due to the photoevaporative flow of 70 Mâ Myrâ1 which yields an expected lifetime of approximately 3 Myr.Peer reviewe
Rituximab monitoring and redosing in pediatric neuromyelitis optica spectrum disorder.
Abstract
OBJECTIVE:
To study rituximab in pediatric neuromyelitis optica (NMO)/NMO spectrum disorders (NMOSD) and the relationship between rituximab, B cell repopulation, and relapses in order to improve rituximab monitoring and redosing.
METHODS:
Multicenter retrospective study of 16 children with NMO/NMOSD receiving 652 rituximab courses. According to CD19 counts, events during rituximab were categorized as "repopulation," "depletion," or "depletion failure" relapses (repopulation threshold CD19 6510
7 10(6) cells/L).
RESULTS:
The 16 patients (14 girls; mean age 9.6 years, range 1.8-15.3) had a mean of 6.1 events (range 1-11) during a mean follow-up of 6.1 years (range 1.6-13.6) and received a total of 76 rituximab courses (mean 4.7, range 2-9) in 42.6-year cohort treatment. Before rituximab, 62.5% had received azathioprine, mycophenolate mofetil, or cyclophosphamide. Mean time from rituximab to last documented B cell depletion and first repopulation was 4.5 and 6.8 months, respectively, with large interpatient variability. Earliest repopulations occurred with the lowest doses. Significant reduction between pre- and post-rituximab annualized relapse rate (ARR) was observed (p = 0.003). During rituximab, 6 patients were relapse-free, although 21 relapses occurred in 10 patients, including 13 "repopulation," 3 "depletion," and 4 "depletion failure" relapses. Of the 13 "repopulation" relapses, 4 had CD19 10-50
7 10(6) cells/L, 10 had inadequate monitoring ( 641 CD19 in the 4 months before relapses), and 5 had delayed redosing after repopulation detection.
CONCLUSION:
Rituximab is effective in relapse prevention, but B cell repopulation creates a risk of relapse. Redosing before B cell repopulation could reduce the relapse risk further.
CLASSIFICATION OF EVIDENCE:
This study provides Class IV evidence that rituximab significantly reduces ARR in pediatric NMO/NMOSD. This study also demonstrates a relationship between B cell repopulation and relapses
Herschel Far-Infrared and Sub-millimeter Photometry for the KINGFISH Sample of Nearby Galaxies
New far-infrared and sub-millimeter photometry from the Herschel Space
Observatory is presented for 61 nearby galaxies from the Key Insights on Nearby
Galaxies: A Far-Infrared Survey with Herschel (KINGFISH) sample. The
spatially-integrated fluxes are largely consistent with expectations based on
Spitzer far-infrared photometry and extrapolations to longer wavelengths using
popular dust emission models. Dwarf irregular galaxies are notable exceptions,
as already noted by other authors, as their 500um emission shows evidence for a
sub-millimeter excess. In addition, the fraction of dust heating attributed to
intense radiation fields associated with photo-dissociation regions is found to
be (21+/-4)% larger when Herschel data are included in the analysis. Dust
masses obtained from the dust emission models of Draine & Li are found to be on
average nearly a factor of two higher than those based on single-temperature
modified blackbodies, as single blackbody curves do not capture the full range
of dust temperatures inherent to any galaxy. The discrepancy is largest for
galaxies exhibiting the coolest far-infrared colors.Comment: Accepted for publication in Ap
Critical Race Theory and Education: racism and anti-racism in educational theory and praxis
What is Critical Race Theory (CRT) and what does it offer educational researchers and practitioners outside the US? This paper addresses these questions by examining the recent history of antiracist research and policy in the UK. In particular, the paper argues that conventional forms of antiracism have proven unable to keep pace with the development of increasingly racist and exclusionary education polices that operate beneath a veneer of professed tolerance and diversity. In particular, contemporary antiracism lacks clear statements of principle and theory that risk reinventing the wheel with each new study; it is increasingly reduced to a meaningless slogan; and it risks appropriation within a reformist âcan doâ perspective dominated by the de-politicized and managerialist language of school effectiveness and improvement. In contrast, CRT offers a genuinely radical and coherent set of approaches that could revitalize critical research in education across a range of inquiries, not only in self-consciously "multicultural" studies. The paper reviews the developing terrain of CRT in education, identifying its key defining elements and the conceptual tools that characterise the work. CRT in education is a fast changing and incomplete project but it can no longer be ignored by the academy beyond North America
Scaling Relations of Spiral Galaxies
We construct a large data set of global structural parameters for 1300 field
and cluster spiral galaxies and explore the joint distribution of luminosity L,
optical rotation velocity V, and disk size R at I- and 2MASS K-bands. The I-
and K-band velocity-luminosity (VL) relations have log-slopes of 0.29 and 0.27,
respectively with sigma_ln(VL)~0.13, and show a small dependence on color and
morphological type in the sense that redder, early-type disk galaxies rotate
faster than bluer, later-type disk galaxies for most luminosities. The VL
relation at I- and K-bands is independent of surface brightness, size and light
concentration. The log-slope of the I- and K-band RL relations is a strong
function of morphology and varies from 0.25 to 0.5. The average dispersion
sigma_ln(RL) decreases from 0.33 at I-band to 0.29 at K, likely due to the
2MASS selection bias against lower surface brightness galaxies. Measurement
uncertainties are sigma_ln(V)~0.09, sigma_ln(L)~0.14 and somewhat larger and
harder to estimate for ln(R). The color dependence of the VL relation is
consistent with expectations from stellar population synthesis models. The VL
and RL residuals are largely uncorrelated with each other; the RV-RL residuals
show only a weak positive correlation. These correlations suggest that scatter
in luminosity is not a significant source of the scatter in the VL and RL
relations. The observed scaling relations can be understood in the context of a
model of disk galaxies embedded in dark matter halos that invokes low mean spin
parameters and dark halo expansion, as we describe in our companion paper
(Dutton et al. 2007). We discuss in two appendices various pitfalls of standard
analytical derivations of galaxy scaling relations, including the Tully-Fisher
relation with different slopes. (Abridged).Comment: Accepted for publication at ApJ. The full document, with
high-resolution B&W and colour figures, is available at
http://www.astro.queensu.ca/~courteau/papers/VRL2007ApJ.pdf . Our data base
for 1303 spiral galaxies is also available at
http://www.astro.queensu.ca/~courteau/data/VRL2007.da
Evolution of the Gas Mass Fraction of Progenitors to Today's Massive Galaxies: ALMA Observations in the CANDELS GOODS-S Field
We present an ALMA survey of dust continuum emission in a sample of 70
galaxies in the redshift range z=2-5 selected from the CANDELS GOODS-S field.
Multi-Epoch Abundance Matching (MEAM) is used to define potential progenitors
of a z = 0 galaxy of stellar mass 1.5 10^11 M_sun. Gas masses are derived from
the 850um luminosity. Ancillary data from the CANDELS GOODS-S survey are used
to derive the gas mass fractions. The results at z<=3 are mostly in accord with
expectations: The detection rates are 75% for the z=2 redshift bin, 50% for the
z=3 bin and 0% for z>=4. The average gas mass fraction for the detected z=2
galaxies is f_gas = 0.55+/-0.12 and f_gas = 0.62+/-0.15 for the z=3 sample.
This agrees with expectations for galaxies on the star-forming main sequence,
and shows that gas fractions have decreased at a roughly constant rate from z=3
to z=0. Stacked images of the galaxies not detected with ALMA give upper limits
to f_gas of <0.08 and <0.15, for the z=2 and z=3 redshift bins. None of our
galaxies in the z=4 and z=5 sample are detected and the upper limit from
stacked images, corrected for low metallicity, is f_gas<0.66. We do not think
that lower gas-phase metallicities can entirely explain the lower dust
luminosities. We briefly consider the possibility of accretion of very
low-metallicity gas to explain the absence of detectable dust emission in our
galaxies at z>4.Comment: Accepted for publication in the Astrophysical Journal. 33 pages; 11
figure
Dissecting the origin of the submillimeter emission in nearby galaxies with Herschel and LABOCA
We model the infrared to submillimeter spectral energy distribution of 11
nearby galaxies of the KINGFISH sample using Spitzer and Herschel data and
compare model extrapolations at 870um (using different fitting techniques) with
LABOCA 870um observations. We investigate how the differences between
predictions and observations vary with model assumptions or environment. At
global scales, we find that modified blackbody models using realistic cold
emissivity indices (beta_c=2 or 1.5) are able to reproduce the 870um observed
emission within the uncertainties for most of the sample. Low values
(beta_c<1.3) would be required in NGC0337, NGC1512 and NGC7793. At local
scales, we observe a systematic 870um excess when using beta_=2.0. The
beta_c=1.5 or the Draine and Li (2007) models can reconcile predictions with
observations in part of the disks. Some of the remaining excesses occur towards
the centres and can be partly or fully accounted for by non-dust contributions
such as CO(3-2) or, to a lesser extent, free-free or synchrotron emission. In
three non-barred galaxies, the remaining excesses rather occur in the disk
outskirts. This could be a sign of a flattening of the submm slope (and
decrease of the effective emissivity index) with radius in these objects.Comment: 31 pages (including appendix), 7 figures, accepted for publication in
MNRA
Modeling Dust and Starlight in Galaxies Observed by Spitzer and Herschel: NGC 628 and NGC 6946
We characterize the dust in NGC628 and NGC6946, two nearby spiral galaxies in
the KINGFISH sample. With data from 3.6um to 500um, dust models are strongly
constrained. Using the Draine & Li (2007) dust model, (amorphous silicate and
carbonaceous grains), for each pixel in each galaxy we estimate (1) dust mass
surface density, (2) dust mass fraction contributed by polycyclic aromatic
hydrocarbons (PAH)s, (3) distribution of starlight intensities heating the
dust, (4) total infrared (IR) luminosity emitted by the dust, and (5) IR
luminosity originating in regions with high starlight intensity. We obtain maps
for the dust properties, which trace the spiral structure of the galaxies. The
dust models successfully reproduce the observed global and resolved spectral
energy distributions (SEDs). The overall dust/H mass ratio is estimated to be
0.0082+/-0.0017 for NGC628, and 0.0063+/-0.0009 for NGC6946, consistent with
what is expected for galaxies of near-solar metallicity. Our derived dust
masses are larger (by up to a factor 3) than estimates based on
single-temperature modified blackbody fits. We show that the SED fits are
significantly improved if the starlight intensity distribution includes a
(single intensity) "delta function" component. We find no evidence for
significant masses of cold dust T<12K. Discrepancies between PACS and MIPS
photometry in both low and high surface brightness areas result in large
uncertainties when the modeling is done at PACS resolutions, in which case
SPIRE, MIPS70 and MIPS160 data cannot be used. We recommend against attempting
to model dust at the angular resolution of PACS.Comment: To be published in Apj, September 2012. See the full version at
http://www.astro.princeton.edu/~ganiano/Papers
The Spitzer Local Volume Legacy: Survey Description and Infrared Photometry
The survey description and the near-, mid-, and far-infrared flux properties
are presented for the 258 galaxies in the Local Volume Legacy (LVL). LVL is a
Spitzer Space Telescope legacy program that surveys the local universe out to
11 Mpc, built upon a foundation of ultraviolet, H-alpha, and HST imaging from
11HUGS (11 Mpc H-alpha and Ultraviolet Galaxy Survey) and ANGST (ACS Nearby
Galaxy Survey Treasury). LVL covers an unbiased, representative, and
statistically robust sample of nearby star-forming galaxies, exploiting the
highest extragalactic spatial resolution achievable with Spitzer. As a result
of its approximately volume-limited nature, LVL augments previous Spitzer
observations of present-day galaxies with improved sampling of the
low-luminosity galaxy population. The collection of LVL galaxies shows a large
spread in mid-infrared colors, likely due to the conspicuous deficiency of 8um
PAH emission from low-metallicity, low-luminosity galaxies. Conversely, the
far-infrared emission tightly tracks the total infrared emission, with a
dispersion in their flux ratio of only 0.1 dex. In terms of the relation
between infrared-to-ultraviolet ratio and ultraviolet spectral slope, the LVL
sample shows redder colors and/or lower infrared-to-ultraviolet ratios than
starburst galaxies, suggesting that reprocessing by dust is less important in
the lower mass systems that dominate the LVL sample. Comparisons with
theoretical models suggest that the amplitude of deviations from the relation
found for starburst galaxies correlates with the age of the stellar populations
that dominate the ultraviolet/optical luminosities.Comment: Accepted for publication in ApJ; Figures 1,8,9 provided as jpeg
Gaps in the cloud cover? Comparing extinction measures in spiral disks
Dust in galaxies can be mapped by either the FIR/sub-mm emission, the optical
or infrared reddening of starlight, or the extinction of a known background
source. We compare two dust extinction measurements for a set of fifteen
sections in thirteen nearby galaxies, to determine the scale of the dusty ISM
responsible for disk opacity: one using stellar reddening and the other a known
background source. In our earlier papers, we presented extinction measurements
of 29 galaxies, based on calibrated counts of distant background objects
identified though foreground disks in HST/WFPC2 images. For the 13 galaxies
that overlap with the Spitzer Infrared Nearby Galaxies Survey (SINGS), we now
compare these results with those obtained from an I-L color map. Our goal is to
determine whether or not a detected distant galaxy indicates a gap in the dusty
ISM, and hence to better understand the nature and geometry of the disk
extinction.
We find that distant galaxies are predominantly in low-extinction sections
marked by the color maps, indicating that their number depends both on the
cloud cover of {\it Spitzer}-resolved dust structures --mostly the spiral
arms--and a diffuse, unresolved underlying disk. We note that our infrared
color map (E[I-L]) underestimates the overall dust presence in these disks
severely, because it implicitly assumes the presence of a dust screen in front
of the stellar distribution.Comment: 22 pages, 2 figures, 3 tables, accepted for publication in A
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