2,889 research outputs found

    Acoustic full-waveform inversion in an elastic world

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    Full-waveform inversion (FWI) is a technique used to obtain high-quality velocity models of the subsurface. Despite the elastic nature of the earth, the anisotropic acoustic wave equation is typically used to model wave propagation in FWI. In part, this simplification is essential for being efficient when inverting large 3D data sets, but it has the adverse effect of reducing the accuracy and resolution of the recovered P-wave velocity models, as well as a loss in potential to constrain other physical properties, such as the S-wave velocity given that amplitude information in the observed data set is not fully used. Here, we first apply conventional acoustic FWI to acoustic and elastic data generated using the same velocity model to investigate the effect of neglecting the elastic component in field data and we find that it leads to a loss in resolution and accuracy in the recovered velocity model. Then, we develop a method to mitigate elastic effects in acoustic FWI using matching filters that transform elastic data into acoustic data and find that it is applicable to marine and land data sets. Tests show that our approach is successful: The imprint of elastic effects on the recovered P-wave models is mitigated, leading to better-resolved models than those obtained after conventional acoustic FWI. Our method requires a guess of VP/VS and is marginally more computationally demanding than acoustic FWI, but much less so than elastic FWI. Read More: https://library.seg.org/doi/10.1190/geo2017-0063.

    Addressing viscous effects in acoustic full-waveform inversion

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    In conventional full-waveform inversion (FWI), viscous effects are typically neglected, and this is likely to adversely affect the recovery of P-wave velocity. We have developed a strategy to mitigate viscous effects based on the use of matching filters with the aim of improving the performance of acoustic FWI. The approach requires an approximate estimate of the intrinsic attenuation model, and it is one to three times more expensive than conventional acoustic FWI. First, we perform 2D synthetic tests to study the impact of viscoacoustic effects on the recorded wavefield and analyze how that affects the recovered velocity models after acoustic FWI. Then, we apply the current method on the generated data and determine that it mitigates viscous effects successfully even in the presence of noise. We find that having an approximate estimate for intrinsic attenuation, even when these effects are strong, leads to improvements in resolution and a more accurate recovery of the P-wave velocity. Then, we implement and develop our method on a 2D field data set using Gabor transforms to obtain an approximate intrinsic attenuation model and inversion frequencies of up to 24 Hz. The analysis of the results indicates that there is an improvement in terms of resolution and continuity of the layers on the recovered P-wave velocity model, leading to an improved flattening of gathers and a closer match of the inverted velocity model with the migrated seismic data

    A systematic review of the discriminating biomechanical parameters during the single leg squat

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    Objective: To determine whether there are common biomechanical parameters when analysing the single leg squat movement to compare pathological and non-pathological groups and whether these parameters are able to effectively distinguish between groups. Methods: Five electronic databases were searched using MESH terms, keywords and phrases across four constructs: squat, biomechanical measures, region of interest, study design. Studies were selected based on inclusion of a quantitative biomechanical measure, compared between a pathological and a non-pathological group, and participants performed a single leg squat movement. Results: Fifteen studies were included and reviewed, where the majority of studies investigated patellofemoral pain. There was considerable variation in the biomechanical outcome measure used to compare between groups. The frontal plane projection angle was the most commonly reported measure. There was considerable variation in the manner in which the single leg squat was performed. Conclusion: Due to variation in how the single leg squat was performed, it was not possible to determine specific biomechanical parameters that distinguish between pathological and non-pathological groups. Frontal plane projection angle appeared to be a parameter that could be effectively utilised. Standardisation of the single leg squat movement is needed to allow comparison between studies of pathological and non-pathological groups

    Flow cytometry method for absolute counting and single-cell phenotyping of mycobacteria

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    Detection and accurate quantitation of viable Mycobacterium tuberculosis is fundamental to understanding mycobacterial pathogenicity, tuberculosis (TB) disease progression and outcomes; TB transmission; drug action, efficacy and drug resistance. Despite this importance, methods for determining numbers of viable bacilli are limited in accuracy and precision owing to inherent characteristics of mycobacterial cell biology – including the tendency to clump, and “differential” culturability – and technical challenges consequent on handling an infectious pathogen under biosafe conditions. We developed an absolute counting method for mycobacteria in liquid cultures using a bench-top flow cytometer, and the low-cost fluorescent dyes Calcein-AM (CA) and SYBR-gold (SG). During exponential growth CA+ cell counts are highly correlated with CFU counts and can be used as a real-time alternative to simplify the accurate standardisation of inocula for experiments. In contrast to CFU counting, this method can detect and enumerate cell aggregates in samples, which we show are a potential source of variance and bias when using established methods. We show that CFUs comprise a sub-population of intact, metabolically active mycobacterial cells in liquid cultures, with CFU proportion varying by growth conditions. A pharmacodynamic application of the flow cytometry method, exploring kinetics of fluorescent probe defined subpopulations compared to CFU is demonstrated. Flow cytometry derived Mycobacterium bovis bacillus Calmette-GuĂ©rin (BCG) time-kill curves differ for rifampicin and kanamycin versus isoniazid and ethambutol, as do the relative dynamics of discrete morphologically-distinct subpopulations of bacilli revealed by this high-throughput single-cell technique

    Subthreshold depression as a risk indicator for major depressive disorder: a systematic review of prospective studies.

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    Objective: In order to examine whether the incidence of major depressive disorder (MDD) is increased in subjects with subthreshold depression, or sD (clinically relevant depressive symptoms, without meeting criteria for a full-blown MDD), we conducted a review of prospective studies examining the incidence of MDD in subjects with sD. Method: A systematic literature search was conducted. For all studies, the relative risk of developing MDD was calculated, based on person-years. Results: Twenty studies (23 comparisons) were found, based on community samples, general medical patients and high-risk subjects. Most comparisons showed that subjects with sD had a consistently larger chance of developing MDD. The studies differed considerably in the definition of sD, the recency (occurrence of the last sD) and the in-/ exclusion of lifetime MDD. Conclusion: The incidence of MDD in subjects with sD is larger than in subjects without sD. Otherwise, the concept of sD is too broad to be used. In future studies, some consensus should be reached regarding the definition of sD

    Report and preliminary results of SONNE cruise SO175, Miami - Bremerhaven, 12.11 - 30.12.2003 : (GAP, Gibraltar Arc Processes)

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    Expedition SO175 using FS Sonne aimed for a multidisciplinerary geoscientific approach with an international group of researchers. Methods covered the entire span from geophysical data acquisition (seafloor mapping, echography, seismic reflection), sediment coring at sites of active fluid venting, in situ heat flow measurements across the entire length of the Gibraltar thrust wedge, the deformation front, landslide bodies, and mud volcanoes, and finally the deployment of a long-term pore pressure probe. Video-supported operations helped to identify fluid vent sites, regions with tectonic activity, and other attractive high priority targets. Qualitative and quantitative examinations took place on board and are continued on land with respect to pore pressure variation, geomicrobiology, sediment- and fluid mobilization, geochemical processes, faunal assemblages (e.g. cold water corals), and gas hydrates (flammable methane-ice-crystals). Main focus of the expedition has been a better understanding of interaction between dynamic processes in a seismically active region region with slow plate convergence. In the context of earthquake nucleation and subduction zone processes, the SO175 research programme had a variety of goals, such as: ‱ To test the frictional behaviour of the abyssal plain sediments. ‱ To explore the temperature field of the 1755 thrust earthquake event via heat flow measurements. ‱ To assess the role of fluid venting and gas hydrate processes control slope stability and mud volcanic activity along the Iberian continental margin. ‱ To measure isotope geochemistry of pore waters and carbonates of deep fluids. ‱ To quantify microbial activity in Gibraltar wedge sediments. ‱ To test whether microseismicity in the area corresponds to in situ pore pressure changes. ‱ To find out if enhanced heat flow max be indicative of active subduction. Initial tentative results during the cruise suggest that there is a component of active thrusting at the base of the wedge, as attested by heat flow data. Based on mostly geochemical evidence, mud volcanism was found less active than previously assumed. Highlights from post-cruise research include the successful deployment of the long-term station and high frictional resistance of all incoming sediment on the three abyssal plains

    Analytic descriptions for transitional nuclei near the critical point

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    Exact solutions of the Bohr Hamiltonian with a five-dimensional square well potential, in isolation or coupled to a fermion by the five-dimensional spin-orbit interaction, are considered as examples of a new class of dynamical symmetry or Bose-Fermi dynamical symmetry. The solutions provide baselines for experimental studies of even-even [E(5)] and odd-mass [E(5|4)] nuclei near the critical point of the spherical to deformed gamma-unstable phase transition.Comment: LaTeX (elsart), 53 pages; typographical correction to (3.15

    High-resolution spectroscopy of the R Coronae Borealis and Other Hydrogen Deficient Stars

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    High-resolution spectroscopy is a very important tool for studying stellar physics, perhaps, particularly so for such enigmatic objects like the R Coronae Borealis and related Hydrogen deficient stars that produce carbon dust in addition to their peculiar abundances. Examples of how high-resolution spectroscopy is used in the study of these stars to address the two major puzzles are presented: (i) How are such rare H-deficient stars created? and (ii) How and where are the obscuring soot clouds produced around the R Coronae Borealis stars?Comment: 16 pages, 9 figures, Astrophysics and Space Science Proceedings, Springer-Verlag, Berlin, 201

    VLT Observations of Turnoff stars in the Globular Cluster NGC 6397

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    VLT-UVES high resolution spectra of seven turnoff stars in the metal-poor globular cluster NGC 6397 have been obtained. Atmospheric parameters and abundances of several elements (Li, Na, Mg, Ca, Sc, Ti, Cr, Fe, Ni, Zn and Ba) were derived for program stars. The mean iron abundance is [Fe/H] = -2.02, with no star-to-star variation. The mean abundances of the alpha-elements (Ca, Ti) and of the iron-peak elements (Sc, Cr, Ni) are consistent with abundances derived for field stars of similar metallicity. Magnesium is also almost solar, consistent with the values found by Idiart & Th\'evenin (2000) when non-LTE effects (NLTE hereafter) are taken into account. The sodium abundance derived for five stars is essentially solar, but one object (A447) is clearly Na deficient. These results are compatible with the expected abundance range estimated from the stochastic evolutionary halo model by Argast et al. (2000) when at the epoch of [Fe/H] ∌\sim -2 the interstellar medium is supposed to become well-mixed.Comment: to appear in A&
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