4,997 research outputs found

    New and interesting records of Brazilian bryophytes

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    This paper presents data on morphology, ecology and distribution of 16 species of bryophytes collected in Pernambuco, Brazil, that are interesting floristic records. Notothylasorbicularis (Schwein.) Sull. is new to Brazil, 11 species are new to the Northeast region of Brazil and 4 species are new to Pernambuco.Dados morfológicos, ecológicos e de distribuição geográfica são apresentados para 16 espécies de briófitas coletadas no Estado de Pernambuco, Brasil. Notothylas orbicularis (Schwein.) Sull. é registrada pela primeira vez para o Brasil, 11 espécies são novas para a região Nordeste e 4 para o Estado de Pernambuco

    Obtenção de padrão de identidade de peito de galinha através de eletroforese SDS-PAGE.

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    Eletroforese de proteínas; Preparação da amostra de extrato protéico de peito de galinha.bitstream/CTAA-2009-09/8951/1/ct84-2005.pd

    Understanding User Behavior: From HPC to HTC

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    AbstractIn this paper, we investigate the differences and similarities in user job submission behavior in High Performance Computing (HPC) and High Throughput Computing (HTC). We consider job submission behavior in terms of parallel batch-wise submissions, as well as delays and pauses in job submission. Our findings show that modeling user-based HTC job submission behavior requires knowledge of the underlying bags of tasks, which is often unavailable. Furthermore, we find evidence that subsequent job submission behavior is not influenced by the different complexities and requirements of HPC and HTC jobs

    Wodel: a domain-specific language for model mutation

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    This is the author's version of the work. It is posted here for your personal use. Not for redistribution. The definitive Version of Record was published in SAC '16: Proceedings of the 31st Annual ACM Symposium on Applied Computing, http://dx.doi.org/10.1145/10.1145/2851613.2851751Model-Driven Engineering (MDE) is a software engineering paradigm that uses models as main assets in all development phases. While many languages for model manipulation exist (e.g., for model transformation or code generation), there is a lack of frameworks to de ne and apply model mutations. A model mutant is a variation of an original model, created by speci c model mutation operations. Model mutation has many applications, for instance, in the areas of model trans- formation testing, model-based testing or education. In this paper, we present a domain-speci c language, called Wodel, for the speci cation and generation of model mu- tants. Wodel is domain-independent, as it can be used to generate mutants of models conforming to arbitrary meta- models. Its development environment is extensible, permit- ting the incorporation of post-processors for di erent appli- cations. As an example, we show an application consisting on the automated generation of exercises for particular do- mains (automata, class diagrams, electronic circuits, etc.).Thanks to Víctor López Rivero for the initial implementation of the Wodel IDE. Work supported by the Spanish Ministry of Economy and Competitivity (TIN2014-52129-R), the Madrid Region (S2013/ICE-3006), and the EU commission (FP7-ICT-2013-10, #611125)

    Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles

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    Here, we identified release of extracellular vesicles (EVs) by the choroid plexus epithelium (CPE) as a new mechanism of blood-brain communication. Systemic inflammation induced an increase in EVs and associated pro-inflammatory miRNAs, including miR-146a and miR-155, in the CSF. Interestingly, this was associated with an increase in amount of multivesicular bodies (MVBs) and exosomes per MVB in the CPE cells. Additionally, we could mimic this using LPS-stimulated primary CPE cells and choroid plexus explants. These choroid plexus-derived EVs can enter the brain parenchyma and are taken up by astrocytes and microglia, inducing miRNA target repression and inflammatory gene up-regulation. Interestingly, this could be blocked in vivo by intracerebroventricular (icv) injection of an inhibitor of exosome production. Our data show that CPE cells sense and transmit information about the peripheral inflammatory status to the central nervous system (CNS) via the release of EVs into the CSF, which transfer this pro-inflammatory message to recipient brain cells. Additionally, we revealed that blockage of EV secretion decreases brain inflammation, which opens up new avenues to treat systemic inflammatory diseases such as sepsis

    Produção de ácidos orgânicos associada à fixação de nitrogênio em mutantes de Gluconacetobacter diazotrophicus

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    O seqüenciamento do genoma de Gluconacetobacter diazotrophicus, bactéria fixadora de nitrogênio, e caracterização do seu proteoma em condições de excesso ou limitação de N em forma disponível para assimilação, forneceram informações gerais sobre a codificação e expressão de proteínas na estirpe PAL5. Além da fixação de nitrogênio, outra característica interessante desta bactéria é sua capacidade de realizar oxidação incompleta da glicose resultando em ácido glicônico e cetoderivados. A associação de ambos os processos pode ser explorado para aplicação biotecnológica em diversos setores industriais, inclusive na indústria alimentícia e agrária. Entretanto, para garantir a eficiência durante aplicação conjunta desses processos é necessário elucidar os mecanismos relacionados com a expressão e regulação da oxidação incompleta da glicose. A partir de uma biblioteca de mutantes construída pela inserção aleatória de transposon no genoma da estirpe PAL5, foram selecionados em condições específicas aqueles mutantes relacionados com a oxidação de glicose a ácido glicônico e/ou cetoderivados. Dos 24 mutantes obtidos, foram caracterizados aqueles relacionados com enzimas chaves para oxidação da glicose a ácido glicônico, com função da NADH-quinona oxidoredutase e com proteína transmenbrana de função desconhecida em relação à capacidade destes mutantes em fixar nitrogênio e produzir ácido glicônico e/ou cetoderivados. Neste trabalho serão apresentados os resultados preliminares da associação de ambos os processos em organismos geneticamente modificados como ferramentas biotecnológicas para produção de ácido 2,5 diceto-glicônico, precursor do intermediário da vitamina C.bitstream/item/42978/1/BOP-53.pd

    Imidazolium ionic liquids as fracture toughening agents in DGEBA-TETA epoxy resin

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    Although epoxy resins are used in a broad variety of applications due to their good mechanical and thermal properties, their low fracture toughness is a limitation, exhibiting brittle behavior. This study explored the potential use of imidazolium ionic liquids (IL) as toughening agents for epoxy resin based on diglycidyl ether of bisphenol A (DGEBA) with triethylenetetramine (TETA) as curing agent. Fracture toughness was evaluated for DGEBA-TETA epoxy resins with eleven imidazolium IL and the best results were found for the IL with the chloride anion and the shortest N-alkyl side chain, C4MImCl. The use of 1.0 phr of C4MImCl lead to the reduction of the crosslink density of the post-cured resin, resulting in the increase of 25.5% in stress intensity factor and 8.2% in tensile strength with no significant loss in other mechanical properties

    O acontecimento teatral como proposta política, paralelos entre o teatro do oprimido e o teatro pós-dramático

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    O teatro pós-dramático, corrente estética estudada principalmente pelo teórico alemão Hans Thies-Lehmann, tem como uma de suas características a exploração do teatro como acontecimento, da particularidade de ser uma tipo de arte que acontece na presença mutua entre aqueles que a executam e seus respectivos espectadores. Assim também ocorre na proposta de Augusto Boal: o teatro do oprimido. Entretanto cada estética apresenta propostas políticas particulares, apresentando pontos de convergencia e divergia, melhores explorados no decorrer desse trabalho
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