O PIBID interdisciplinar na interface com a educação do campo, cultura escolar e meio ambiente: um diálogo com a Antropologia

Anais do II Seminário Seminário Estadual PIBID do Paraná: tecendo saberes / organizado por Dulcyene Maria Ribeiro e Catarina Costa Fernandes — Foz do Iguaçu: Unioeste; Unila, 2014O presente ensaio faz parte das reflexões desenvolvidas durante as atividades desenvolvidas pelo grupo de acadêmicos de História da Unicentro/PR que participam do subprojeto interdisciplinar do PIBID. Aqui, procurou-se fazer uma discussão inicial acerca dos conceitos de cultura e de educação do campo e suas especificidades em um contexto antropológico. Abordaremos aspectos de como as interações culturais se realizam dentro da sociedade e das escolas do campo, e as implicações das relações socioculturais no processo educativo como um todo, em especial nos currículos. O texto está disposto da seguinte forma: em um primeiro momento apresentaremos nosso problema, qual seja a conceituação antropológica de cultura, em especial a cultura escolar do campo. Em um segundo momento, será realizada uma discussão acerca do papel da escola e do educador, levando em consideração temáticas relacionadas à cultura campesina, como educação ambiental. O arcabouço teórico se da no contexto da diversidade cultural encontrado nas escolas do campo, bem como na relação urbano-rural e suas particularidade

The ρ(1S,2S)\rho(1S,2S), ψ(1S,2S)\psi(1S,2S), Υ(1S,2S)\Upsilon(1S,2S) and ψt(1S,2S)\psi_t(1S,2S) mesons in a double pole QCD Sum Rule

We use the method of double pole QCD sum rule which is basically a fit with two exponentials of the correlation function, where we can extract the masses and decay constants of mesons as a function of the Borel mass. We apply this method to study the mesons: $\rho(1S,2S)$, $\psi(1S,2S)$, $\Upsilon(1S,2S)$ and $\psi_t(1S,2S)$. We also present predictions for the toponiuns masses $\psi_t(1S,2S)$ of m(1S)=357 GeV and m(2S)=374 GeV.Comment: 14 pages, 11 figures in Braz J Phys (2016

A 1,000 Frames/s Programmable Vision Chip with Variable Resolution and Row-Pixel-Mixed Parallel Image Processors

A programmable vision chip with variable resolution and row-pixel-mixed parallel image processors is presented. The chip consists of a CMOS sensor array, with row-parallel 6-bit Algorithmic ADCs, row-parallel gray-scale image processors, pixel-parallel SIMD Processing Element (PE) array, and instruction controller. The resolution of the image in the chip is variable: high resolution for a focused area and low resolution for general view. It implements gray-scale and binary mathematical morphology algorithms in series to carry out low-level and mid-level image processing and sends out features of the image for various applications. It can perform image processing at over 1,000 frames/s (fps). A prototype chip with 64 × 64 pixels resolution and 6-bit gray-scale image is fabricated in 0.18 μm Standard CMOS process. The area size of chip is 1.5 mm × 3.5 mm. Each pixel size is 9.5 μm × 9.5 μm and each processing element size is 23 μm × 29 μm. The experiment results demonstrate that the chip can perform low-level and mid-level image processing and it can be applied in the real-time vision applications, such as high speed target tracking

INFECÇÃO PELO VÍRUS INFLUENZA A H1N1 EM GESTANTES / INFLUENZA A H1N1 VIRUS INFECTION IN PREGNANT WOMEN

Introdução: Gestantes têm um risco aumentado para infecção pelo vírus influenza e suas complicações. Objetivo: Avaliar o comprometimento sistêmico e o tratamento de gestantes infectadas pelo vírus Influenza A H1N1. Métodos: Estudo descritivo e retrospectivo do tipo documental. Foram analisados os aspectos radiológicos, clínicos e demográficos de todos os casos de gestantes infectadas pelo vírus Influenza A H1N1 internadas no Serviço de Obstetrícia e Ginecologia do Hospital Universitário da Universidade Federal do Maranhão - HUUFMA. Resultados: Foram avaliados 10 casos de gestantes infectadas pelo vírus Influenza A H1N1. A média de idade foi de 20,9 ± 4,7, variando entre 14 e 30 anos. No início dos sintomas, 5 (50%) mulheres estavam no terceiro trimestre de gestação, sendo que dessas, 4 (80%) evoluíram com complicações. Febre foi o sintoma mais comum, estando presente em todos os casos. Cinco (50%) mulheres apresentaram, além da gestação, pelo menos um fator de risco para complicações. Sete (70%) gestantes apresentaram complicações, sendo que 3 (42,9%) tinham fatores de risco. Duas (20%) pacientes evoluíram para o óbito. Cinco (50%) pacientes iniciaram tratamento específico para o vírus após 48 horas de início dos sintomas, sendo que todas (100%) tiveram complicações. As radiografias do momento da internação evidenciaram infiltrado intersticial peri-hilar e consolidação. Conclusão: O presente estudo sugere que as características da infecção pelo vírus H1N1 nas gestantes admitidas no HUUFMA se assemelham às características de outras gestantes estudadas em pesquisas nos diversos lugares do mundo.Palavras-chave: Gestantes. Vírus da Influenza A, subtipo H1N1. Febre. Fatores de risco.AbstractIntroduction: Pregnant women are at increased risk for influenza and its complications. Objective: Evaluate the systemic involvement and the treatment of pregnant women infected with Influenza A virus, H1N1 subtype. Methods: Descriptive and retrospective study, documentary type. We reviewed the radiological, clinical and demographic aspects of all cases of pregnant women infected with H1N1 virus hospitalized in the Obstetrics and Gynecology Sector of University Hospital of the Federal University of Maranhão. Results: Ten cases of pregnant women infected with H1N1 virus were analyzed. The average age of patients was 20,9 ± 4,7, ranging between 14 e 30 years. At the onset of symptoms, 5 (50%) women were in the third trimester of pregnancy, and of these amount, 4(80%) had complications. Fever was the most common symptom, being present in all cases. Five (50%) women had, in addition to pregnancy, at least one risk factor to develop complications. Seven (70%) patients had complications, of which 3 (42,9%) had risk factors. Two (20%) patients subsequently died. Five (50%) patients started specific treatment for the virus 48 hours after the onset of symptoms, and from these amount, all (100%) of them had complications. Interstitial perihilar infiltrate and consolidation were seen in radiographs at admission. Conclusion: The present study suggest that the characteristics of the infection due to H1N1 I pregnant women, admitted in HUUFMA are similar to the characteristics in other pregnant women observed in a variety of other researches around the world.Keywords: Pregnant women. Influenza A virus, H1N1 subtype. Fever. Risk Factors

Noradrenergic ‘Tone’ Determines Dichotomous Control of Cortical Spike-Timing-Dependent Plasticity

Norepinephrine (NE) is widely distributed throughout the brain. It modulates intrinsic currents, as well as amplitude and frequency of synaptic transmission affecting the ‘signal-to-noise ratio’ of sensory responses. In the visual cortex, α1- and β-adrenergic receptors (AR) gate opposing effects on long-term plasticity of excitatory transmission. Whether and how NE recruits these plastic mechanisms is not clear. Here, we show that NE modulates glutamatergic inputs with different efficacies for α1- and β-AR. As a consequence, the priming of synapses with different NE concentrations produces dose-dependent competing effects that determine the temporal window of spike-timing dependent plasticity (STDP). While a low NE concentration leads to long-term depression (LTD) over broad positive and negative delays, a high NE concentration results in bidirectional STDP restricted to very narrow intervals. These results indicate that the local availability of NE, released during emotional arousal, determines the compound modulatory effect and the output of STDP

Distinct Early Molecular Responses to Mutations Causing vLINCL and JNCL Presage ATP Synthase Subunit C Accumulation in Cerebellar Cells

Variant late-infantile neuronal ceroid lipofuscinosis (vLINCL), caused by CLN6 mutation, and juvenile neuronal ceroid lipofuscinosis (JNCL), caused by CLN3 mutation, share clinical and pathological features, including lysosomal accumulation of mitochondrial ATP synthase subunit c, but the unrelated CLN6 and CLN3 genes may initiate disease via similar or distinct cellular processes. To gain insight into the NCL pathways, we established murine wild-type and CbCln6nclf/nclf cerebellar cells and compared them to wild-type and CbCln3Δex7/8/Δex7/8 cerebellar cells. CbCln6nclf/nclf cells and CbCln3Δex7/8/Δex7/8 cells both displayed abnormally elongated mitochondria and reduced cellular ATP levels and, as cells aged to confluence, exhibited accumulation of subunit c protein in Lamp 1-positive organelles. However, at sub-confluence, endoplasmic reticulum PDI immunostain was decreased only in CbCln6nclf/nclf cells, while fluid-phase endocytosis and LysoTracker® labeled vesicles were decreased in both CbCln6nclf/nclf and CbCln3Δex7/8/Δex7/8 cells, though only the latter cells exhibited abnormal vesicle subcellular distribution. Furthermore, unbiased gene expression analyses revealed only partial overlap in the cerebellar cell genes and pathways that were altered by the Cln3Δex7/8 and Cln6nclf mutations. Thus, these data support the hypothesis that CLN6 and CLN3 mutations trigger distinct processes that converge on a shared pathway, which is responsible for proper subunit c protein turnover and neuronal cell survival

Histopathological evaluation of thrombus in patients presenting with stent thrombosis. A multicenter European study: a report of the prevention of late stent thrombosis by an interdisciplinary global European effort consortium

Background Stent thrombosis (ST) is a rare but serious complication following percutaneous coronary intervention. Analysis of thrombus composition from patients undergoing catheter thrombectomy may provide important insights into the pathological processes leading to thrombus formation. We performed a large-scale multicentre study to evaluate thrombus specimens in patients with ST across Europe. Methods Patients presenting with ST and undergoing thrombus aspiration were eligible for inclusion. Thrombus collection was performed according to a standardized protocol and specimens were analysed histologically at a core laboratory. Serial tissue cross sections were stained with haematoxylin–eosin (H&E), Carstairs and Luna. Immunohistochemistry was performed to identify leukocyte subsets, prothrombotic neutrophil extracellular traps (NETs), erythrocytes, platelets, and fibrinogen. Results Overall 253 thrombus specimens were analysed; 79 (31.2%) from patients presenting with early ST, 174 (68.8%) from late ST; 79 (31.2%) were from bare metal stents, 166 (65.6%) from drug-eluting stents, 8 (3.2%) were from stents of unknown type. Thrombus specimens displayed heterogeneous morphology with platelet-rich thrombus and fibrin/fibrinogen fragments most abundant; mean platelet coverage was 57% of thrombus area. Leukocyte infiltrations were hallmarks of both early and late ST (early: 2260 ± 1550 per mm2 vs. late: 2485 ± 1778 per mm2; P = 0.44); neutrophils represented the most prominent subset (early: 1364 ± 923 per mm2 vs. late: 1428 ± 1023 per mm2; P = 0.81). Leukocyte counts were significantly higher compared with a control group of patients with thrombus aspiration in spontaneous myocardial infarction. Neutrophil extracellular traps were observed in 23% of samples. Eosinophils were present in all stent types, with higher numbers in patients with late ST in sirolimus-and everolimus-eluting stents. Conclusion In a large-scale study of histological thrombus analysis from patients presenting with ST, thrombus specimens displayed heterogeneous morphology. Recruitment of leukocytes, particularly neutrophils, appears to be a hallmark of ST. The presence of NETs supports their pathophysiological relevance. Eosinophil recruitment suggests an allergic component to the process of ST

An association between unrecognized gastroesophageal reflux disease and excessive daytime sleepiness in Taiwanese subjects suspected to have liver disease: a pilot study

<p>Abstract</p> <p>Background</p> <p>In traditional Chinese culture, liver disease is believed to underlie excessive daytime sleepiness (EDS). Consequently, Chinese patients with complaints of EDS and physicians who treat them suspect that a liver abnormality is present. If liver disease is ruled out, these patients are often discharged without treatment. Gastroesophageal reflux disease (GERD) is a common disorder also associated with EDS. This pilot study was undertaken to determine the prevalence of GERD among Taiwanese patients with complaints of EDS suspected to be related to liver disease but in whom no evidence for the latter was found.</p> <p>Methods</p> <p>From July 2009 to December 2009, 121 outpatients who presented to or were referred to the Department of Gastroenterology and Hepatology of the Chiayi Gung Memorial Hospital for evaluation of a complaint of EDS thought to be due to liver disease were examined. Demographic data were collected, and physical examinations and liver function tests were performed. Forty-eight patients had liver disease and were excluded. The Chinese Epworth Sleepiness Scale questionnaire (Chinese ESS) and the Chinese Gastroesophageal Reflux Disease Questionnaire (CGERDQ) were then administered to 73 included patients.</p> <p>Results</p> <p>More than half (56.2%) of the included patients were found to suffer from GERD. Patients with symptoms of GERD had higher mean CGERDQ scores than patients without symptoms of the disorder (18.88 ± 5.49 and 5.56 ± 3.57, respectively; <it>P </it>< 0.001). Patients with symptoms of GERD also had higher mean Chinese ESS scores than patients without symptoms (8.80 ± 5.49 and 3.13 ± 3.50, respectively; <it>P </it>< 0.001). Chinese ESS scores indicative of EDS were observed in 48.8% of patients with symptoms of GERD and in 3.1% of those without symptoms (<it>P </it>< 0.001). Differences between the two groups retained their significance after controlling for potential confounders.</p> <p>Conclusions</p> <p>A significant percentage of Taiwanese patients who complained of EDS and were admitted to our Hepatology/Gastroenterology Department due to a suspicion of liver disease actually had symptoms of GERD. Further studies are needed to ascertain whether treatment of GERD will effectively resolve EDS in these patients.</p