11,331 research outputs found
Radial Velocities as an Exoplanet Discovery Method
The precise radial velocity technique is a cornerstone of exoplanetary
astronomy. Astronomers measure Doppler shifts in the star's spectral features,
which track the line-of/sight gravitational accelerations of a star caused by
the planets orbiting it. The method has its roots in binary star astronomy, and
exoplanet detection represents the low-companion-mass limit of that
application. This limit requires control of several effects of much greater
magnitude than the signal sought: the motion of the telescope must be
subtracted, the instrument must be calibrated, and spurious Doppler shifts
"jitter" must be mitigated or corrected. Two primary forms of instrumental
calibration are the stable spectrograph and absorption cell methods, the former
being the path taken for the next generation of spectrographs. Spurious,
apparent Doppler shifts due to non-center-of-mass motion (jitter) can be the
result of stellar magnetic activity or photospheric motions and granulation.
Several avoidance, mitigation, and correction strategies exist, including
careful analysis of line shapes and radial velocity wavelength dependence.Comment: Invited review chapter. 13pp. v2 includes corrections to Eqs 3-6,
updated references, and minor edit
Probable detection of starlight reflected from the giant exoplanet orbiting tau Bootis
Giant planets orbiting stars other than the Sun are clearly detectable
through precise radial-velocity measurements of the orbital reflex motion of
the parent star. In the four years since the discovery of the companion to the
star 51 Peg, similar low-amplitude ``Doppler star wobbles'' have revealed the
presence of some 20 planets orbiting nearby solar-type stars. Several of these
newly-discovered planets are very close to their parent stars, in orbits with
periods of only a few days. Being an indirect technique, however, the
reflex-velocity method has little to say about the sizes or compositions of the
planets, and can only place lower limits on their masses. Here we report the
use of high-resolution optical spectroscopy to achieve a probable detection of
the Doppler-shifted signature of starlight reflected from one of these objects,
the giant exoplanet orbiting the star tau Bootis. Our data give the planet's
orbital inclination i=29 degrees, indicating that its mass is some 8 times that
of Jupiter, and suggest strongly that the planet has the size and reflectivity
expected for a gas-giant planet.Comment: 15 pages, 4 figures. (Fig 1 and equation for epsilon on p1 para 2
revised; changed from double to single spacing
Long-term magnetic activity of a sample of M-dwarf stars from the HARPS program II. Activity and radial velocity
Due to their low mass and luminosity, M dwarfs are ideal targets if one hopes
to find low-mass planets similar to Earth by using the radial velocity (RV)
method. However, stellar magnetic cycles could add noise or even mimic the RV
signal of a long-period companion. Following our previous work that studied the
correlation between activity cycles and long-term RV variations for K dwarfs we
now expand that research to the lower-end of the main sequence. Our objective
is to detect any correlations between long-term activity variations and the
observed RV of a sample of M dwarfs. We used a sample of 27 M-dwarfs with a
median observational timespan of 5.9 years. The cross-correlation function
(CCF) with its parameters RV, bisector inverse slope (BIS), full-width-at-half-
maximum (FWHM) and contrast have been computed from the HARPS spectrum. The
activity index have been derived using the Na I D doublet. These parameters
were compared with the activity level of the stars to search for correlations.
We detected RV variations up to ~5 m/s that we can attribute to activity cycle
effects. However, only 36% of the stars with long-term activity variability
appear to have their RV affected by magnetic cycles, on the typical timescale
of ~6 years. Therefore, we suggest a careful analysis of activity data when
searching for extrasolar planets using long-timespan RV data.Comment: 20 pages, 12 figures, 3 tables, accepted for publication in Astronomy
and Astophysic
An ectromelia virus profilin homolog interacts with cellular tropomyosin and viral A-type inclusion protein
<p>Abstract</p> <p>Background</p> <p>Profilins are critical to cytoskeletal dynamics in eukaryotes; however, little is known about their viral counterparts. In this study, a poxviral profilin homolog, ectromelia virus strain Moscow gene 141 (ECTV-PH), was investigated by a variety of experimental and bioinformatics techniques to characterize its interactions with cellular and viral proteins.</p> <p>Results</p> <p>Profilin-like proteins are encoded by all orthopoxviruses sequenced to date, and share over 90% amino acid (aa) identity. Sequence comparisons show highest similarity to mammalian type 1 profilins; however, a conserved 3 aa deletion in mammalian type 3 and poxviral profilins suggests that these homologs may be more closely related. Structural analysis shows that ECTV-PH can be successfully modelled onto both the profilin 1 crystal structure and profilin 3 homology model, though few of the surface residues thought to be required for binding actin, poly(L-proline), and PIP<sub>2 </sub>are conserved. Immunoprecipitation and mass spectrometry identified two proteins that interact with ECTV-PH within infected cells: alpha-tropomyosin, a 38 kDa cellular actin-binding protein, and the 84 kDa product of vaccinia virus strain Western Reserve (VACV-WR) 148, which is the truncated VACV counterpart of the orthopoxvirus A-type inclusion (ATI) protein. Western and far-western blots demonstrated that the interaction with alpha-tropomyosin is direct, and immunofluorescence experiments suggest that ECTV-PH and alpha-tropomyosin may colocalize to structures that resemble actin tails and cellular protrusions. Sequence comparisons of the poxviral ATI proteins show that although full-length orthologs are only present in cowpox and ectromelia viruses, an ~ 700 aa truncated ATI protein is conserved in over 90% of sequenced orthopoxviruses. Immunofluorescence studies indicate that ECTV-PH localizes to cytoplasmic inclusion bodies formed by both truncated and full-length versions of the viral ATI protein. Furthermore, colocalization of ECTV-PH and truncated ATI protein to protrusions from the cell surface was observed.</p> <p>Conclusion</p> <p>These results suggest a role for ECTV-PH in intracellular transport of viral proteins or intercellular spread of the virus. Broader implications include better understanding of the virus-host relationship and mechanisms by which cells organize and control the actin cytoskeleton.</p
Constraining GRB Emission Physics with Extensive Early-Time, Multiband Follow-up
Understanding the origin and diversity of emission processes responsible for
Gamma-ray Bursts (GRBs) remains a pressing challenge. While prompt and
contemporaneous panchromatic observations have the potential to test
predictions of the internal-external shock model, extensive multiband imaging
has been conducted for only a few GRBs. We present rich, early-time, multiband
datasets for two \swift\ events, GRB 110205A and GRB 110213A. The former shows
optical emission since the early stages of the prompt phase, followed by the
steep rising in flux up to ~1000s after the burst ( with
). We discuss this feature in the context of the
reverse-shock scenario and interpret the following single power-law decay as
being forward-shock dominated. Polarization measurements, obtained with the
RINGO2 instrument mounted on the Liverpool Telescope, also provide hints on the
nature of the emitting ejecta. The latter event, instead, displays a very
peculiar optical to near-infrared lightcurve, with two achromatic peaks. In
this case, while the first peak is probably due to the onset of the afterglow,
we interpret the second peak to be produced by newly injected material,
signifying a late-time activity of the central engine.Comment: 48 pages,11 figures, 24 tables. Accepted to The Astrophysical Journa
TPH2 polymorphisms and expression in Prader-Willi syndrome subjects with differing genetic subtypes
Prader-Willi syndrome (PWS) is a genetic imprinting disease that causes developmental and behavioral disturbances resulting from loss of expression of genes from the paternal chromosome 15q11-q13 region. In about 70% of subjects, this portion of the paternal chromosome is deleted, while 25% have two copies of the maternal chromosome 15, or uniparental maternal disomy (UPD; the remaining subjects have imprinting center defects. There are several documented physical and behavioral differences between the two major PWS genetic subtypes (deletion and UPD) indicating the genetic subtype plays a role in clinical presentation. Serotonin is known to be disturbed in PWS and affects both eating behavior and compulsion, which are reported to be abnormal in PWS. We investigated the tryptophan hydroxylase gene (TPH2), the rate-limiting enzyme in the production of brain serotonin, by analyzing three different TPH2 gene polymorphisms, transcript expression, and correlation with PWS genetic subtype. DNA and RNA from lymphoblastoid cell lines derived from 12 PWS and 12 comparison subjects were used for the determination of genetic subtype, TPH2 polymorphisms and quantitative RT-PCR analysis. A similar frequency of TPH2 polymorphisms was seen in the PWS and comparison subjects with PWS deletion subjects showing increased expression with one or more TPH2 polymorphism. Both PWS deletion and PWS UPD subjects had significantly lower TPH2 expression than control subjects and PWS deletion subjects had significantly lower TPH2 expression compared with PWS UPD subjects. PWS subjects with 15q11-q13 deletions had lower TPH2 expression compared with PWS UPD or control subjects, requiring replication and further studies to identify the cause including identification of disturbed gene interactions resulting from the deletion process
Planetary companions around the K giant stars 11 UMi and HD 32518
11 UMi and HD 32518 belong to a sample of 62 K giant stars that has been
observed since February 2004 using the 2m Alfred Jensch telescope of the
Th\"uringer Landessternwarte (TLS) to measure precise radial velocities (RVs).
The aim of this survey is to investigate the dependence of planet formation on
the mass of the host star by searching for planetary companions around
intermediate-mass giants. An iodine absorption cell was used to obtain accurate
RVs for this study. Our measurements reveal that the RVs of 11 UMi show a
periodic variation of 516.22 days. The RV curve of HD 32518 shows sinusoidal
variations with a period of 157.54 days. The HIPPARCOS photometry as well as
our H\alpha core flux measurements reveal no variability with the RV period.
Thus, Keplerian motion is the most likely explanation for the observed RV
variations for both giant stars. An exoplanet with a minimum mass of 10.5
Jupiter masses orbits the K giant 11 UMi. The K1 III giant HD 32518 hosts a
planetary companion with a minimum mass of 3.0 Jupiter masses in a nearly
circular orbit. These are the 4th and 5th planets published from this TLS
survey.Comment: 11 pages, 16 figure
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