871 research outputs found
Knowing when to talk? Plant genome editing as a site for pre-engagement institutional reflexivity
This is the final version. Available on open access from SAGE Publications via the DOI in this recordCitizen and stakeholder engagement is frequently portrayed as vital for socially accountable science policy but there is a growing understanding of how institutional dynamics shape engagement exercises in ways that prevent them from realising their full potential. Limited attention has been devoted to developing the means to expose institutional features, allow policy-makers to reflect on how they will shape engagement and respond appropriately. Here, therefore, we develop and test a methodological framework to facilitate pre-engagement institutional reflexivity with one of the United Kingdom’s eminent science organisations as it grappled with a new, high-profile and politicised technology, genome editing. We show how this approach allowed policy-makers to reflect on their institutional position and enrich decision-making at a time when they faced pressure to legitimate decisions with engagement. Further descriptions of such pre-engagement institutional reflexivity are needed to better bridge theory and practice in the social studies of science.Engineering and Physical Sciences Research Council (EPSRC)Biotechnology and Biological Sciences Research Council (BBSRC
A spectral-timing model for ULXs in the supercritical regime
Ultraluminous X-ray sources (ULXs) with luminosities lying between ∼3 × 1039 and 2 × 1040 erg s−1 represent a contentious sample of objects as their brightness, together with a lack of unambiguous mass estimates for the vast majority of the central objects, leads to a degenerate scenario where the accretor could be a stellar remnant (black hole or neutron star) or intermediate-mass black hole (IMBH). Recent, high-quality observations imply that the presence of IMBHs in the majority of these objects is unlikely unless the accretion flow somehow deviates strongly from expectation based on objects with known masses. On the other hand, physically motivated models for supercritical inflows can re-create the observed X-ray spectra and their evolution, although have been lacking a robust explanation for their variability properties. In this paper, we include the effect of a partially inhomogeneous wind that imprints variability on to the X-ray emission via two distinct methods. The model is heavily dependent on both inclination to the line of sight and mass accretion rate, resulting in a series of qualitative and semiquantitative predictions. We study the time-averaged spectra and variability of a sample of well-observed ULXs, finding that the source behaviours can be explained by our model in both individual cases as well as across the entire sample, specifically in the trend of hardness-variability power. We present the covariance spectra for these sources for the first time, which shed light on the correlated variability and issues associated with modelling broad ULX spectra
Flora of Singapore: Checklist and bibliography
A checklist of all species of bryophytes, lycophytes, ferns, gymnosperms
and angiosperms that are found in the wild (native, naturalised and casual) in Singapore is
presented. We have attempted to account for all names of species and infraspecific taxa that
have ever been recorded for Singapore, along with the pertinent publications that reported each
of these names. For each currently accepted name, the synonyms of relevance for Singapore
are included. The native or non-native status for all taxa is given, along with the most recent
national conservation assessment applied to each native taxon. If we were aware that the most
recent assessment required an update, the taxon is newly assessed here. The checklist includes
2654 native taxa, 479 naturalised/casual taxa and 101 cryptogenic taxa
The three-dimensional random field Ising magnet: interfaces, scaling, and the nature of states
The nature of the zero temperature ordering transition in the 3D Gaussian
random field Ising magnet is studied numerically, aided by scaling analyses. In
the ferromagnetic phase the scaling of the roughness of the domain walls,
, is consistent with the theoretical prediction .
As the randomness is increased through the transition, the probability
distribution of the interfacial tension of domain walls scales as for a single
second order transition. At the critical point, the fractal dimensions of
domain walls and the fractal dimension of the outer surface of spin clusters
are investigated: there are at least two distinct physically important fractal
dimensions. These dimensions are argued to be related to combinations of the
energy scaling exponent, , which determines the violation of
hyperscaling, the correlation length exponent , and the magnetization
exponent . The value is derived from the
magnetization: this estimate is supported by the study of the spin cluster size
distribution at criticality. The variation of configurations in the interior of
a sample with boundary conditions is consistent with the hypothesis that there
is a single transition separating the disordered phase with one ground state
from the ordered phase with two ground states. The array of results are shown
to be consistent with a scaling picture and a geometric description of the
influence of boundary conditions on the spins. The details of the algorithm
used and its implementation are also described.Comment: 32 pp., 2 columns, 32 figure
Energy landscape of relaxed amorphous silicon
We analyze the structure of the energy landscape of a well-relaxed 1000-atom
model of amorphous silicon using the activation-relaxation technique (ART
nouveau). Generating more than 40,000 events starting from a single minimum, we
find that activated mechanisms are local in nature, that they are distributed
uniformly throughout the model and that the activation energy is limited by the
cost of breaking one bond, independently of the complexity of the mechanism.
The overall shape of the activation-energy-barrier distribution is also
insensitive to the exact details of the configuration, indicating that
well-relaxed configurations see essentially the same environment. These results
underscore the localized nature of relaxation in this material.Comment: 8 pages, 12 figure
A 78 Day X-Ray Period Detected from NGC 5907 ULX1 by Swift
We report the detection of a 78.1 ± 0.5 day period in the X-ray light curve of the extreme ultraluminous X-ray source NGC 5907 ULX1 ( erg s−1), discovered during an extensive monitoring program with Swift. These periodic variations are strong, with the observed flux changing by a factor of ~3–4 between the peaks and the troughs of the cycle; our simulations suggest that the observed periodicity is detected comfortably in excess of 3σ significance. We discuss possible origins for this X-ray period, but conclude that at the current time we cannot robustly distinguish between orbital and super-orbital variations
Transverse Phase Locking for Vortex Motion in Square and Triangular Pinning Arrays
We analyze transverse phase locking for vortex motion in a superconductor
with a longitudinal DC drive and a transverse AC drive. For both square and
triangular arrays we observe a variety of fractional phase locking steps in the
velocity versus DC drive which correspond to stable vortex orbits. The locking
steps are more pronounced for the triangular arrays which is due to the fact
that the vortex motion has a periodic transverse velocity component even for
zero transverse AC drive. All the steps increase monotonically in width with AC
amplitude. We confirm that the width of some fractional steps in the square
arrays scales as the square of the AC driving amplitude. In addition we
demonstrate scaling in the velocity versus applied DC driving curves at
depinning and on the main step, similar to that seen for phase locking in
charge-density wave systems. The phase locking steps are most prominent for
commensurate vortex fillings where the interstitial vortices form symmetrical
ground states. For increasing temperature, the fractional steps are washed out
very quickly, while the main step gains a linear component and disappears at
melting. For triangular pinning arrays we again observe transverse phase
locking, with the main and several of the fractional step widths scaling
linearly with AC amplitude.Comment: 10 pages, 14 postscript figure
Metastable States in Spin Glasses and Disordered Ferromagnets
We study analytically M-spin-flip stable states in disordered short-ranged
Ising models (spin glasses and ferromagnets) in all dimensions and for all M.
Our approach is primarily dynamical and is based on the convergence of a
zero-temperature dynamical process with flips of lattice animals up to size M
and starting from a deep quench, to a metastable limit. The results (rigorous
and nonrigorous, in infinite and finite volumes) concern many aspects of
metastable states: their numbers, basins of attraction, energy densities,
overlaps, remanent magnetizations and relations to thermodynamic states. For
example, we show that their overlap distribution is a delta-function at zero.
We also define a dynamics for M=infinity, which provides a potential tool for
investigating ground state structure.Comment: 34 pages (LaTeX); to appear in Physical Review
Low-energy excitations in the three-dimensional random-field Ising model
The random-field Ising model (RFIM), one of the basic models for quenched
disorder, can be studied numerically with the help of efficient ground-state
algorithms. In this study, we extend these algorithm by various methods in
order to analyze low-energy excitations for the three-dimensional RFIM with
Gaussian distributed disorder that appear in the form of clusters of connected
spins. We analyze several properties of these clusters. Our results support the
validity of the droplet-model description for the RFIM.Comment: 10 pages, 9 figure
Toward mid-infrared, subdiffraction, spectral-mapping of human cells and tissue: SNIM (scanning near-field infrared microscopy) tip fabrication
Scanning near-field infrared microscopy (SNIM) potentially enables subdiffraction, broadband mid-infrared (MIR:3–25-μm wavelength range) spectral-mapping of human cells and tissue for real-time molecular sensing, with prospective use in disease diagnosis. SNIM requires an MIR-transmitting tip of small aperture for photon collection. Here, chalcogenide-glass optical fibers are reproducibly tapered at one end to form a MIR transmitting tip for SNIM. A wet-etching method is used to form the tip. The tapering sides of the tip are Al-coated. These Al-coated tapered-tips exhibit near-field power-confinement when acting either as the launch-end or exit-end of the MIR optical fiber. We report first time optimal cleaving of the end of the tapered tip using focused ion beam milling. A flat aperture is produced at the end of the tip, which is orthogonal to the fiber-axis and of controlled diameter. A FIB-cleaved aperture is used to collect MIR spectra of cells mounted on a transflection plate, under illumination of a synchrotron- generated wideband MIR beam
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