Bond-Bending and Bond-Stretching Phonons in Ferromagnetic La_0.7Sr_0.3MnO_3

Longitudinal optical phonons with oxygen character were measured in La_0.7Sr_0.3MnO_3 by inelastic neutron scattering in the (1 0 0) cubic direction and results were compared with shell model predictions. Measurements were performed in several Brillouin zones, which enabled us to identify the eigenvectors independent of the shell model. All major disagreements between model predictions and experimental results are primarily due to the anomalous downward dispersion of the bond-stretching vibration. The main new result is that the rhombohedral distortion of the cubic lattice makes the bond-stretching vibrations interact strongly with bond-bending modes folded into the cubic Brillouin zone

A Measurement of Secondary Cosmic Microwave Background Anisotropies with Two Years of South Pole Telescope Observations

We present the first three-frequency South Pole Telescope (SPT) cosmic microwave background (CMB) power spectra. The band powers presented here cover angular scales 2000 < ℓ < 9400 in frequency bands centered at 95, 150, and 220 GHz. At these frequencies and angular scales, a combination of the primary CMB anisotropy, thermal and kinetic Sunyaev-Zel'dovich (SZ) effects, radio galaxies, and cosmic infrared background (CIB) contributes to the signal. We combine Planck/HFI and SPT data at 220 GHz to constrain the amplitude and shape of the CIB power spectrum and find strong evidence for nonlinear clustering. We explore the SZ results using a variety of cosmological models for the CMB and CIB anisotropies and find them to be robust with one exception: allowing for spatial correlations between the thermal SZ effect and CIB significantly degrades the SZ constraints. Neglecting this potential correlation, we find the thermal SZ power at 150 GHz and ℓ = 3000 to be 3.65 ± 0.69 μK^2, and set an upper limit on the kinetic SZ power to be less than 2.8 μK^2 at 95% confidence. When a correlation between the thermal SZ and CIB is allowed, we constrain a linear combination of thermal and kinetic SZ power: D^(tSZ)_(3000) + 0.5D^(kSZ)_(3000) = 4.60 ± 0.63 μK^2, consistent with earlier measurements. We use the measured thermal SZ power and an analytic, thermal SZ model calibrated with simulations to determine σ_8 = 0.807 ± 0.016. Modeling uncertainties involving the astrophysics of the intracluster medium rather than the statistical uncertainty in the measured band powers are the dominant source of uncertainty on σ_8. We also place an upper limit on the kinetic SZ power produced by patchy reionization; a companion paper uses these limits to constrain the reionization history of the universe

Physiological and molecular features of glucocorticoid actions in the gastrointestinal tract

Ever since their first successful application in the treatment of RA patients in the late 1950, GCs have been the gold standard for the treatment of multiple inflammatory and neoplastic diseases. There are, however, also severe adverse effects that denote restrictions upon the use of GCs. In particular oral application of GCs can lead to gastrointestinal complications that may severely affect the patient’s quality of life and lead to a reduced tolerability of the therapy. In this work I have described and characterized gastroparesis as a so far unrecognized effect of GCs in the gastrointestinal tract that is mediated via trans-activation of genes. Changes in gene expression characteristic for M2 macrophage polarization proved to be unrelated to gastroparesis. Similarly, an involvement of two genes specifically expressed in the gastrointestinal tract could be ruled out. In contrast, I could confirm that genes related to the regulation of NO production contribute to gastroparesis. A decrease in iron availability through up-regulation of Lcn2 was found to partially impact on gastric motility whereas reduced substrate availability for NO synthesis through up-regulation of Arg2 proved to be responsible for impaired gastric emptying. Hence, GC therapy causes gastroparesis by increasing gene expression in the stomach in a DNA-binding-dependent manner thereby diminishing the availability of NO required for gastric motility. Complete prevention of gastroparesis was achieved by an exogenous supply of L-arginine thus providing a means to overcome the observed effect with the help of a dietary supplement. My study also offers a possible explanation for the anti-emetic effect of GCs that has been used for long to interfere with CINV without knowing the underlying mechanism. Now it appears likely that reducing NO availability in the stomach is the way how GCs counteract CINV, which is accompanied by increased NO production. Unfortunately, further elucidation of this process is impossible in rodent models due to the inability of mice and rats to vomit. Taken together, the identification and characterization of GC-induced gastroparesis sheds new light on both adverse and beneficial activities of GCs in the stomach and may help to optimize therapy in the future for the patients’ benefit

A Simple, Quick, and Precise Procedure for the Determination of Water in Organic Solvents

A procedure for the UV/VIS-spectroscopic determination of water by the use of a solvatochromic pyridiniumphenolate betaine is given. The water content of organic solvents is calculated by a two parameter equation from λmax of the dye. A typical, detection limit is of the order of 1 mg in 1 ml solvent for routine spectrometers. The parameters for the determination of water are given for a number of commonly used solvents

General procedure to initialize the cyclic soil water balance by the Thornthwaite and Mather method

The original Thornthwaite and Mather method, proposed in 1955 to calculate a climatic monthly cyclic soil water balance, is frequently used as an iterative procedure due to its low input requirements and coherent estimates of water balance components. Using long term data sets to establish a characteristic water balance of a location, the initial soil water storage is generally assumed to be at field capacity at the end of the last month of the wet season, unless the climate is (semi-) arid when the soil water storage is lower than the soil water holding capacity. To close the water balance, several iterations might be necessary, which can be troublesome in many situations. For (semi-) arid climates with one dry season, Mendon a derived in 1958 an equation to quantify the soil water storage monthly at the end of the last month of the wet season, which avoids iteration procedures and closes the balance in one calculation. The cyclic daily water balance application is needed to obtain more accurate water balance output estimates. In this note, an equation to express the water storage for the case of the occurrence of more than one dry season per year is presented as a generalization of Mendon a's equation, also avoiding iteration procedures

Lattice dynamics and electron-phonon coupling in Sr2RuO4

The lattice dynamics in Sr$_2$RuO$_4$ has been studied by inelastic neutron scattering combined with shell-model calculations. The in-plane bond-stretching modes in Sr$_2$RuO$_4$ exhibit a normal dispersion in contrast to all electronically doped perovskites studied so far. Evidence for strong electron phonon coupling is found for c-polarized phonons suggesting a close connection with the anomalous c-axis charge transport in Sr$_2$RuO$_4$.Comment: 11 pages, 8 figures 2 table

Dynamical properties across a quantum phase transition in the Lipkin-Meshkov-Glick model

It is of high interest, in the context of Adiabatic Quantum Computation, to better understand the complex dynamics of a quantum system subject to a time-dependent Hamiltonian, when driven across a quantum phase transition. We present here such a study in the Lipkin-Meshkov-Glick (LMG) model with one variable parameter. We first display numerical results on the dynamical evolution across the LMG quantum phase transition, which clearly shows a pronounced effect of the spectral avoided level crossings. We then derive a phenomenological (classical) transition model, which already shows some closeness to the numerical results. Finally, we show how a simplified quantum transition model can be built which strongly improve the classical approach, and shed light on the physical processes involved in the whole LMG quantum evolution. From our results, we argue that the commonly used description in term of Landau-Zener transitions is not appropriate for our model.Comment: 7 pages, 5 figures; corrected reference