282 research outputs found
Forensic capabilities for service-oriented architectures
This report describes a framework to provide on-line forensic capabilities to service oriented architecture via Forensic Web Services (FWS) and runtime execution monitoring. The FWS is a new type of web services to be used by other web services (of an independent agency) to securely maintain transactional records of interest between other web services. The framework uses runtime execution monitoring to search the transactional log for interesting (or suspicious) service invocation sequences to recreate non-repudiable evidence of transactional history for use in a court of law.Approved for public release; distribution is unlimited.Contract Number: N6600107WR0022
A cognitive approach to user perception of multimedia quality: An empirical investigation
Whilst multimedia technology has been one of the main contributing factors behind the Web's success, delivery of personalized multimedia content has been a desire seldom achieved in practice. Moreover, the perspective adopted is rarely viewed from a cognitive styles standpoint, notwithstanding the fact that they have significant effects on users’ preferences with respect to the presentation of multimedia content. Indeed, research has thus far neglected to examine the effect of cognitive styles on users’ subjective perceptions of multimedia quality. This paper aims to examine the relationships between users’ cognitive styles, the multimedia quality of service delivered by the underlying network, and users’ quality of perception (understood as both enjoyment and informational assimilation) associated with the viewed multimedia content. Results from the empirical study reported here show that all users, regardless of cognitive style, have higher levels of understanding of informational content in multimedia video clips (represented in our study by excerpts from television programmes) with weak dynamism, but that they enjoy moderately dynamic clips most. Additionally, multimedia content was found to significantly influence users’ levels of understanding and enjoyment. Surprisingly, our study highlighted the fact that Bimodal users prefer to draw on visual sources for informational purposes, and that the presence of text in multimedia clips has a detrimental effect on the knowledge acquisition of all three cognitive style groups
Adverse Childhood Experiences and Acute Coronary Syndrome in Adulthood
Research studies demonstrate that exposure to adverse childhood experiences (ACEs) lead to physical and mental health consequences in adulthood, including cardiovascular disease (Dong, Giles, Felitti et al, 2004; Felitti, Anda, Nordenberg, et al, 1998). One potential mechanism linking ACEs to cardiovascular disease is impaired social competence necessary for successful relationships and adequate social support. In the current study, the impact of ACEs on social support and subsequent incidence of acute coronary syndrome (ACS) was examined in a cohort of 6,596 older Seventh-day Adventists. After controlling for sociodemographic, lifestyle, and psychological factors, ACE exposure predicted increased risk of ACS by 31% for males only. Similarly, exposure to 3 or more ACEs resulted in a more than 3-fold increased risk of ACS for males compared to no ACEs. While ACE exposure had positive associations with negative social support and negative spouse/partner support, there were no associations with social integration. Social integration and support measures did not mediate the ACE-ACS relationship; even in supplementary analyses combining cardiac-related mortality and ACS. However, several gender and poverty moderation effects emerged. Church attendance decreased the risk of ACS in females in poverty, after controls and ACE exposure. Among females in poverty, negative social support and negative spouse support increased the risk of ACS incidence after controls and ACE exposure. Among males not in poverty, suppression effects were found, suggesting that having low negative support and negative spouse/partner support decreased the risk of ACS incidence as well as combined ACS and cardiac-mortality. Although non-significant, suppression patterns for poverty subgroups revealed that any increase in negative support or spouse/partner support, leads to increase in ACS incidence and combined ACS and cardiac mortality. Together, the findings highlight the long-term impact of ACEs on cardiac health, and the importance of considering non-traditional risk factors (such social support and church attendance), as critical pathways that can lead to cardiac health outcomes. Further examination of religiousness and emotion regulation pathways should follow to further elucidate on the mechanisms that underlie the ACE-ACS relationship
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BoBBLE: ocean-atmosphere interaction and its impact on the South Asian monsoon
The Bay of Bengal (BoB) plays a fundamental role in controlling the weather systems that make up the South Asian summer monsoon system. In particular,the southern BoB has cooler sea surface temperature (SST) that influence ocean-atmosphere interaction and impact on the monsoon. Compared to the southeast, the southwestern BoB is cooler, more saline, receives much less rain, and is influenced by the Summer Monsoon Current(SMC). To examine the impact of these features on the monsoon, the BoB Boundary Layer Experiment (BoBBLE) was jointly undertaken by India and the UK during June–July 2016. Physical and bio-geochemical observations were made using a CTD, five ocean gliders, a uCTD, a VMP, two ADCPs, Argo floats, drifting buoys, meteorological sensors and upper air radiosonde balloons. The observations were made along a zonal section at 8◦N between 85.3◦E and 89◦E with a 10-day time series at 89◦E, 8◦N. This paper presents the new observed features of the southern BoB from the BoBBLE field program, supported by satellite data. Key results from the BoBBLE field campaign show the Sri Lanka Dome and the SMC in different stages of their seasonal evolution and two freshening events during which salinity decreased in the upper layer leading to the formation of thick barrier layers. BoBBLE observations were taken during a suppressed phase of the intraseasonal oscillation; they captured in detail the warming of the ocean mixed layer and preconditioning of the atmosphere to convection
Mixing to monsoons: Air-sea interactions in the bay of Bengal
More than 1 billion people depend on rainfall from the South Asian monsoon for their livelihoods. Summertime monsoonal precipitation is highly variable on intraseasonal time scales, with alternating "active" and "break" periods. These intraseasonal oscillations in large-scale atmospheric convection and winds are closely tied to 1°C-2°C variations of sea surface temperature in the Bay of Bengal
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Large-Eddy Simulation of Flow over Two-Dimensional Obstacles: High Drag States and Mixing
A three-dimensional large-eddy simulation (LES) model was used to examine how stratified flow interacts with bottom obstacles in the coastal ocean. Bottom terrain representing a 2D ridge was modeled using a finite-volume approach with ridge height (4.5 m) and width (~30 m) and water depth (~45 m) appropriate for coastal regions. Temperature and salinity profiles representative of coastal conditions giving constant buoyancy frequency were applied with flow velocities between 0.16 and 0.4 m s⁻¹. Simulations using a free-slip lower boundary yielded flow responses ranging from transition flows with relatively high internal wave pressure drag to supercritical flow with relatively small internal wave drag. Cases with high wave drag exhibited strong lee-wave systems with wavelength of ~100 m and regions of turbulent overturning. Application of bottom drag caused a 5–10-m-thick bottom boundary layer to form, which greatly reduced the strength of lee-wave systems in the transition cases. A final simulation with bottom drag, but with a much larger obstacle height (16 m) and width (~400 m), produced a stronger lee-wave response, indicating that large obstacle flow is not influenced as much by bottom roughness. Flow characteristics for the larger obstacle were more similar to hydraulic flow, with lee waves that are relatively short in comparison with the obstacle width. The relatively strong effect of bottom roughness on the small obstacle wave drag suggests that small-scale bottom variations may be ignored in internal wave drag parameterizations. However, the more significant wave drag from larger-scale obstacles must still be considered and may be responsible for mixing and momentum transfer at distances far from the obstacle source
ASIRI : an ocean–atmosphere initiative for Bay of Bengal
Author Posting. © American Meteorological Society, 2016. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Bulletin of the American Meteorological Society 97 (2016): 1859–1884, doi:10.1175/BAMS-D-14-00197.1.Air–Sea Interactions in the Northern Indian Ocean (ASIRI) is an international research effort (2013–17) aimed at understanding and quantifying coupled atmosphere–ocean dynamics of the Bay of Bengal (BoB) with relevance to Indian Ocean monsoons. Working collaboratively, more than 20 research institutions are acquiring field observations coupled with operational and high-resolution models to address scientific issues that have stymied the monsoon predictability. ASIRI combines new and mature observational technologies to resolve submesoscale to regional-scale currents and hydrophysical fields. These data reveal BoB’s sharp frontal features, submesoscale variability, low-salinity lenses and filaments, and shallow mixed layers, with relatively weak turbulent mixing. Observed physical features include energetic high-frequency internal waves in the southern BoB, energetic mesoscale and submesoscale features including an intrathermocline eddy in the central BoB, and a high-resolution view of the exchange along the periphery of Sri Lanka, which includes the 100-km-wide East India Coastal Current (EICC) carrying low-salinity water out of the BoB and an adjacent, broad northward flow (∼300 km wide) that carries high-salinity water into BoB during the northeast monsoon. Atmospheric boundary layer (ABL) observations during the decaying phase of the Madden–Julian oscillation (MJO) permit the study of multiscale atmospheric processes associated with non-MJO phenomena and their impacts on the marine boundary layer. Underway analyses that integrate observations and numerical simulations shed light on how air–sea interactions control the ABL and upper-ocean processes.This work was sponsored by the U.S. Office of Naval Research (ONR) in an ONR Departmental Research Initiative (DRI), Air–Sea Interactions in Northern Indian Ocean (ASIRI), and in a Naval Research Laboratory project, Effects of Bay of Bengal Freshwater Flux on Indian Ocean Monsoon (EBOB). ASIRI–RAWI was funded under the NASCar DRI of the ONR. The Indian component of the program, Ocean Mixing and Monsoons (OMM), was supported by the Ministry of Earth Sciences of India.2017-04-2
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The growth of the oceanic boundary layer during the COARE intensive observational period: Large Eddy simulation results
A principal goal of the Tropical Ocean Global Atmosphere (TOGA) Coupled Ocean-Atmosphere Response Experiment (COARE) is to gain an understanding of the processes that control mixing in the upper 100 m of the western tropical Pacific warm pool. The warm pool is an important heat reservoir for the global ocean and is responsible for many of the observed climatic changes associated with El Nino/Southern Oscillation (ENSO) events. This water mass is highly sensitive to mixed-layer processes that are controlled by surface heat, salinity, and momentum fluxes. During most of the year, these fluxes are dominated by solar heating and occasional squalls that freshen the top of the mixed layer and force shallow mixing of about 10-20 m. From November to April, the usual weather pattern is frequently altered by westerly wind bursts that are forced by tropical cyclones and intraseasonal oscillations. These wind bursts generate a strong eastward surface current and can force mixing as deep as 100 m over a period of days. Observations from the intensive observation period (IOP) in COARE indicate that mixed-layer deepening is accompanied by strong turbulence dissipation at the mixed layer base. A short westerly wind burst occurred during the first leg of TOGA-COARE, and lasted about 4-5 days. During this period, the maximum winds were about 10 m s{sup -1}, and the resulting eastward surface flow was about 0.5 m s{sup -1}. The strength of this event was somewhat weaker than a typical westerly wind burst, but the mixed-layer structure and growth are similar to the more vigorous wind bursts discussed
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2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling
Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people every year and so far, there are no therapeutic cures available. Even though animal and histological models have been of great aid in understanding disease mechanisms and identifying possible therapeutic strategies, in order to find disease-modifying solutions there is still a critical need for systems that can provide more predictive and physiologically relevant results. One possible avenue is the development of patient-derived models, e.g. by reprogramming patient somatic cells into human induced pluripotent stem cells (hiPSCs), which can then be differentiated into any cell type for modelling. These systems contain key genetic information from the donors, and therefore have enormous potential as tools in the investigation of pathological mechanisms underlying disease phenotype, and progression, as well as in drug testing platforms. hiPSCs have been widely cultured in 2D systems, but in order to mimic human brain complexity, 3D models have been proposed as a more advanced alternative. This review will focus on the use of patient-derived hiPSCs to model AD, PD, HD and ALS. In brief, we will cover the available stem cells, types of 2D and 3D culture systems, existing models for neurodegenerative diseases, obstacles to model these diseases in vitro, and current perspectives in the field
Identification of Shell Colour Pigments in Marine Snails Clanculus pharaonius and C. margaritarius (Trochoidea; Gastropoda)
This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. https://creativecommons.org/publicdomain/zero/1.0/
The attached file is the published version of the article
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