88 research outputs found
The effect of additions of anticorrosive pigments on the cathodic delamitation and wear resistance of an epoxy powder coating
The cathodic delamination and wear resistance of epoxy powder coatings were evaluated after adding 3 % (by wt.) of calcium ion exchanged micropigments from amorphous synthetic silica. The materials were manufactured through the innovative and economical hot mixing method, and three different coatings were considered: commercial epoxy, epoxy without micropigments submitted to the hot mixing treatment, and epoxy with micropigments. The curing kinetics of the powder coatings was studied in order to evaluate the possible effects of the micropigments on the epoxy, using differential scanning calorimetry (DSC). In addition, mechanical properties of coatings (hardness and scratch resistance) and their wear resistance (reciprocal tribometer tests) were assessed. After provoking a controlled mechanical failure in the coatings, their delamination resistance was analyzed by scanning Kelvin probe (SKP). The delamination front was calculated after adding a drop of 3.5 % NaCl solution and taking measurements for 26 days. The results show that the corrosion attack progresses through a cathodic delamination mechanism. The addition of corrosion inhibitors in epoxy powder coatings has not only allowed a considerable improvement in delamination resistance, but has also led to greater mechanical and wear resistance. At the same time, it has simultaneously reduced the chances for mechanical failure of the coating and decreased the progression rate of damage, if it occurs. The study has also been completed with electrochemical impedance spectroscopy and polarization measured of fully-immersed defective coatings in 3.5 % NaCl.The authors acknowledge financial support from the European Union's Horizon 2020 research and innovation program through grant agreement No 766437 (ESSIAL project)
Static quantities of the W boson in the SU_L(3) X U_X(1) model with right-handed neutrinos
The static electromagnetic properties of the boson, and
, are calculated in the SU_L(3)} \times U_X(1) model with
right-handed neutrinos. The new contributions from this model arise from the
gauge and scalar sectors. In the gauge sector there is a new contribution from
a complex neutral gauge boson and a singly-charged gauge boson .
The mass of these gauge bosons, called bileptons, is expected to be in the
range of a few hundreds of GeV according to the current bounds from
experimental data. If the bilepton masses are of the order of 200 GeV, the size
of their contribution is similar to that obtained in other weakly coupled
theories. However the contributions to both and are
negligible for very heavy or degenerate bileptons. As for the scalar sector, an
scenario is examined in which the contribution to the form factors is
identical to that of a two-Higgs-doublet model. It is found that this sector
would not give large corrections to and .Comment: New material included. Final version to apppear in Physical Review
Two-body decays in the minimal 331 model
The two-body decays of the extra neutral boson Z_2 predicted by the minimal
331 model are analyzed. At the three-level it can decay into standard model
particles as well as exotic quarks and the new gauge bosons predicted by the
model. The decays into a lepton pair are strongly suppressed, with and . In the bosonic
sector, Z_2 would decay mainly into a pair of bilepton gauge bosons, with a
branching ratio below the 0.1 level. The Z_2 boson has thus a leptophobic and
bileptophobic nature and it would decay dominantly into quark pairs. The
anomaly-induced decays and , which occurs
at the one-loop level are studied. It is found that and at most. As for the and decays, with H a relatively light Higgs boson, they
are induced via Z'-Z mixing. It is obtained that
and . We also examine the flavor changing neutral
current decays and , which may have branching
fractions as large as and , respectively, and thus may be of
phenomenological interest.Comment: 14 pages, 3 figures, submitted to Physical Review
Efecto de las fuentes de polen sobre el rendimiento en la extracción de aceite y perfil de ácidos grasos de las semillas de dátil (Phoenix dactylifera L.) cultivar Medjool de México
The present investigation aimed to assess the effect of pollen sources on the mass, dimension, oil content and fatty acid profile of the seeds from female palms of the Medjool date cultivar. The palms were pollinated with Deglet Noor, Khadrawy, Medjool and Zahidi cultivars. In addition, three palms were pollinated as the treatment control. The fatty acids were evaluated by gas chromatography-mass spectrometry. The surface morphology of date seed powder was examined using SEM, before and after n-hexane interaction. The seeds of the Medjool treatment had the greatest mass (1.42 g), but the lowest oil content (5.37% w/w); the control seeds showed smaller mass (1.21 g), but higher oil content (13.57% w/w). The proportion of fatty acids varied significantly among the treatments with respect to the control. The most abundant fatty acids were oleic (C18:1), lauric (C12:0), myristic (C14:0), palmitic (C16:0), linoleic (C18:2), and stearic (C18:0). Together these fatty acids presented a composition between 98.3 and 98.67% for treatments, and 99.0% for the control. The results indicate that the pollen sources from Deglet Noor, Khadrawy, Medjool and Zahidi cultivars had a significant effect on mass, dimension, oil content and fatty acid profile of the seeds of the date cultivar Medjool. The date seed oil could be used as edible oil, in food products, and in pharmaceutical and cosmetic applications.La presente investigación tuvo como objetivo evaluar el efecto de las fuentes de polen, sobre la masa, dimensión, contenido de aceite y el perfil de ácidos grasos de las semillas de dátil del cultivar Medjool. Las palmas hembras del cultivar Medjool fueron polinizadas con cultivares Deglet Noor, Khadrawy, Medjool y Zahidi. Además, tres palmas fueron polinizadas como tratamiento control. Los ácidos grasos se evaluaron por cromatografía de gases-espectrometría de masas. La morfología de la superficie del polvo de semillas de dátil se examinó utilizando un equipo SEM, antes y después de la interacción n-hexano. Las semillas del tratamiento Medjool resultaron con mayor masa (1,42 g), pero menor contenido de aceite (5,37% p/p); la semilla control, mostró una masa más pequeña (1,21 g), pero un mayor contenido de aceite (13,57% p/p). La composición de ácidos grasos varió significativamente entre los tratamientos con respecto al control. Los ácidos grasos mayoritarios fueron: oleico (C18:1), láurico (C12:0), mirístico (C14:0), palmítico (C16:0), linoleico (C18:2) and esteárico (C18:0). En total, estos ácidos grasos alcanzan una composición entre 98.3 y 98.67% para los tratamientos, y 99.0% para el control. Los resultados indican que la fuente de polen de los cultivares Deglet Noor, Khadrawy, Medjool y Zahidi tiene un efecto significativo sobre la masa, dimensión, contenido de aceite y el perfil de ácidos grasos de la semilla del cultivar de dátil Medjool. El aceite de la semilla de dátil, podría usarse como aceite comestible, productos alimenticios, aplicaciones farmacéuticas y cosméticas
Generating Neutrino Mass in the 331 Model
A mechanism for generating small tree-level Majorana mass for neutrinos is
implemented in the 331 Model. No additional fermions or scalars need to be
added, and no mass scale greater than a few TeV is invoked.Comment: LaTex, 7 pages, no figures. Revised version to appear in Phys. Rev.
Discrete symmetries, invisible axion and lepton number symmetry in an economic 3-3-1 model
We show that Peccei-Quinn and lepton number symmetries can be a natural
outcome in a 3-3-1 model with right-handed neutrinos after imposing a Z_11 x
Z_2 symmetry. This symmetry is suitably accommodated in this model when we
augmented its spectrum by including merely one singlet scalar field. We work
out the breaking of the Peccei-Quinn symmetry, yielding the axion, and study
the phenomenological consequences. The main result of this work is that the
solution to the strong CP problem can be implemented in a natural way, implying
an invisible axion phenomenologically unconstrained, free of domain wall
formation and constituting a good candidate for the cold dark matter.Comment: 17 pages, Revtex
An Interdisciplinary Model for Graphical Representation
International audienceThe paper questions whether data-driven and problem-driven models are sufficient for a software to automatically represent a meaningful graphi-cal representation of scientific findings. The paper presents descriptive and prescriptive case studies to understand the benefits and the shortcomings of existing models that aim to provide graphical representations of data-sets. First, the paper considers data-sets coming from the field of software metrics and shows that existing models can provide the expected outcomes for descriptive scientific studies. Second, the paper presents data-sets coming from the field of human mobility and sustainable development, and shows that a more comprehensive model is needed in the case of prescriptive scientific fields requiring interdisciplinary research. Finally, an interdisciplinary problem-driven model is proposed to guide the software users, and specifically scientists, to produce meaningful graphical representation of research findings. The proposal is indeed based not only on a data-driven and/or problem-driven model but also on the different knowledge domains and scientific aims of the experts, who can provide the information needed for a higher-order structure of the data, supporting the graphical representation output
Epidemiological trends of HIV/HCV coinfection in Spain, 2015-2019
Altres ajuts: Spanish AIDS Research Network; European Funding for Regional Development (FEDER).Objectives: We assessed the prevalence of anti-hepatitis C virus (HCV) antibodies and active HCV infection (HCV-RNA-positive) in people living with HIV (PLWH) in Spain in 2019 and compared the results with those of four similar studies performed during 2015-2018. Methods: The study was performed in 41 centres. Sample size was estimated for an accuracy of 1%. Patients were selected by random sampling with proportional allocation. Results: The reference population comprised 41 973 PLWH, and the sample size was 1325. HCV serostatus was known in 1316 PLWH (99.3%), of whom 376 (28.6%) were HCV antibody (Ab)-positive (78.7% were prior injection drug users); 29 were HCV-RNA-positive (2.2%). Of the 29 HCV-RNA-positive PLWH, infection was chronic in 24, it was acute/recent in one, and it was of unknown duration in four. Cirrhosis was present in 71 (5.4%) PLWH overall, three (10.3%) HCV-RNA-positive patients and 68 (23.4%) of those who cleared HCV after anti-HCV therapy (p = 0.04). The prevalence of anti-HCV antibodies decreased steadily from 37.7% in 2015 to 28.6% in 2019 (p < 0.001); the prevalence of active HCV infection decreased from 22.1% in 2015 to 2.2% in 2019 (p < 0.001). Uptake of anti-HCV treatment increased from 53.9% in 2015 to 95.0% in 2019 (p < 0.001). Conclusions: In Spain, the prevalence of active HCV infection among PLWH at the end of 2019 was 2.2%, i.e. 90.0% lower than in 2015. Increased exposure to DAAs was probably the main reason for this sharp reduction. Despite the high coverage of treatment with direct-acting antiviral agents, HCV-related cirrhosis remains significant in this population
Anti-tumour necrosis factor discontinuation in inflammatory bowel disease patients in remission: study protocol of a prospective, multicentre, randomized clinical trial
Background:
Patients with inflammatory bowel disease who achieve remission with anti-tumour necrosis factor (anti-TNF) drugs may have treatment withdrawn due to safety concerns and cost considerations, but there is a lack of prospective, controlled data investigating this strategy. The primary study aim is to compare the rates of clinical remission at 1?year in patients who discontinue anti-TNF treatment versus those who continue treatment.
Methods:
This is an ongoing, prospective, double-blind, multicentre, randomized, placebo-controlled study in patients with Crohn?s disease or ulcerative colitis who have achieved clinical remission for ?6?months with an anti-TNF treatment and an immunosuppressant. Patients are being randomized 1:1 to discontinue anti-TNF therapy or continue therapy. Randomization stratifies patients by the type of inflammatory bowel disease and drug (infliximab versus adalimumab) at study inclusion. The primary endpoint of the study is sustained clinical remission at 1?year. Other endpoints include endoscopic and radiological activity, patient-reported outcomes (quality of life, work productivity), safety and predictive factors for relapse. The required sample size is 194 patients. In addition to the main analysis (discontinuation versus continuation), subanalyses will include stratification by type of inflammatory bowel disease, phenotype and previous treatment. Biological samples will be obtained to identify factors predictive of relapse after treatment withdrawal.
Results:
Enrolment began in 2016, and the study is expected to end in 2020.
Conclusions:
This study will contribute prospective, controlled data on outcomes and predictors of relapse in patients with inflammatory bowel disease after withdrawal of anti-TNF agents following achievement of clinical remission.
Clinical trial reference number:
EudraCT 2015-001410-1
Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).
Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)
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