677 research outputs found
Expression of carbonic anhydrase IX suggests poor response to therapy in rectal cancer
Contains fulltext :
80703.pdf (publisher's version ) (Closed access
Reply: Randomised studies with translational end points are required to further elucidate the prognostic and predictive value of CA IX
Thermodynamic properties of sea air
Very accurate thermodynamic potential functions are available for fluid water, ice, seawater and humid air covering wide ranges of temperature and pressure conditions. They permit the consistent computation of all equilibrium properties as, for example, required for coupled atmosphere-ocean models or the analysis of observational or experimental data. With the exception of humid air, these potential functions are already formulated as international standards released by the International Association for the Properties of Water and Steam (IAPWS), and have been adopted in 2009 for oceanography by IOC/UNESCO. <br><br> In this paper, we derive a collection of formulas for important quantities expressed in terms of the thermodynamic potentials, valid for typical phase transitions and composite systems of humid air and water/ice/seawater. Particular attention is given to equilibria between seawater and humid air, referred to as "sea air" here. In a related initiative, these formulas will soon be implemented in a source-code library for easy practical use. The library is primarily aimed at oceanographic applications but will be relevant to air-sea interaction and meteorology as well. <br><br> The formulas provided are valid for any consistent set of suitable thermodynamic potential functions. Here we adopt potential functions from previous publications in which they are constructed from theoretical laws and empirical data; they are briefly summarized in the appendix. The formulas make use of the full accuracy of these thermodynamic potentials, without additional approximations or empirical coefficients. They are expressed in the temperature scale ITS-90 and the 2008 Reference-Composition Salinity Scale
Universality in the Crossover between Edge Channel and Bulk Transport in the Quantum Hall Regime
We present a new theoretical approach for the integer quantum Hall effect,
which is able to describe the inter-plateau transitions as well as the
transition to the Hall insulator. We find two regimes (metallic and insulator
like) of the top Landau level, in which the dissipative bulk current appears in
different directions. The regimes are separated by a temperature invariant
point.Comment: 4 page, 2 eps figures included, submitte
Injection of photoelectrons into dense argon gas
The injection of photoelectrons in a gaseous or liquid sample is a widespread
technique to produce a cold plasma in a weakly--ionized system in order to
study the transport properties of electrons in a dense gas or liquid. We report
here the experimental results of photoelectron injection into dense argon gas
at the temperatureT=142.6 K as a function of the externally applied electric
field and gas density. We show that the experimental data can be interpreted in
terms of the so called Young-Bradbury model only if multiple scattering effects
due to the dense environment are taken into account when computing the
scattering properties and the energetics of the electrons.Comment: 18 pages, 10 figures, figure nr. 10 has been redrawn, to be submitted
to Plasma Sources Science and Technolog
FDCCS16 molecular simulation of the thermophysical properties and phase behaviour of impure CO2 relevant to CCS
Impurities from the CCS chain can greatly influence the physical properties of CO2. This has important design, safety and cost implications for the compression, transport and storage of CO2. There is an urgent need to understand and predict the properties of impure CO2 to assist with CCS implementation. However, CCS presents demanding modelling requirements. A suitable model must both accurately and robustly predict CO2 phase behaviour over a wide range of temperature and pressure, and maintain that predictive power for CO2 mixtures with numerous, mutually interacting chemical species. A promising technique to address this task is molecular simulation. It offers a molecular approach, with foundations in firmly established physical principles, along with the potential to predict the wide range of physical properties required for CCS. The quality of predictions from molecular simulation depends on accurate force-fields to de- scribe the interactions between CO2 and other molecules. Unfortunately, there is currently no universally applicable method to obtain force-fields suitable for molecular simulation. In this paper we present two methods of obtaining force-fields: the first being semi-empirical and the second using ab-initio quantum-chemical calculations. In the first approach we optimise the impurity force-field against measurements of the phase and pressure-volume behaviour of CO2 binary mixtures with N2, O2, Ar and H2. A gradient-free optimiser allows us to use the simulation itself as the underlying model. This leads to accurate and robust predictions under conditions relevant to CCS. In the second approach we use quantum-chemical calculations to produce ab-initio evaluations of the interactions between CO2 and relevant impurities, taking N2 as an exemplar. We use a modest number of these calculations to train a machine-learning algorithm, known as a Gaussian process, to describe these data. The resulting model is then able to accurately predict a much broader set of ab-initio force-field calculations at comparatively low numerical cost. Although our method is not yet ready to be implemented in a molecular simulation, we outline the necessary steps here. Such simulations have the potential to deliver first-principles simulation of the thermodynamic properties of impure CO2, without fitting to experimental data
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