Could Cheese Be the Missing, Hard, Stable Currency to Fortify Self-Sufficiency of Pastoralist Communities?

Traditional pastoral existence in Africa has always necessitated close, sustainable interaction with a harsh natural environment. Pastoralists, such as the indigenous Parakuyo Maasai of Tanzania traditionally depend on fresh cow’s milk as a staple. They are among the few African ethnic groups that still live as small, socially intact associations close to nature. Unfortunately, fresh milk is difficult to store and inevitably, times of plenty fluctuate with the times of hunger that threaten cultural retreat. Milk storage is particularly challenging in an arid climate without refrigeration and at such times, survival takes precedence over prosperity. We describe an ongoing pilot project that has attempted to address these hardships, facilitate traditional subsistence and the economic autonomy of the Parakuyo Maasai. We proposed that a simple solution is cheese production. The “Maasai-cheese” project (www.vsf.at) was implemented in 2011 and instructs sustainable cheese production on the Maasai boma using locally sourced assets, combining Austrian experience of cheese production with Maasai experience of arid dairy farming. Anticipated gains for the Maasai are becoming realised: (i) Family incomes can be assured during hardship. During the dry season Zebu cattle do not produce enough milk that can be sold or exchanged. However, cheese produced and matured earlier can be sold at this time; (ii) Antibiotic abuse in cattle can be drastically decreased. When cheese is a valuable commodity there is a strong disincentive to treat cattle with antibiotics, which prevent fermentation. (iii) Cheese is a sought-after commodity in Africa. This pilot initiative is being well received as the demand for cheese in Africa is enormous. In particular, technical know-how has been a limiting factor until now

Endangered Sustainable Innovation: Indigenous Milk Hygiene and Preservation Techniques by Maasai Too Valuable to Lose

The indigenous Parakuyo Maasai communities of Tanzania are traditional pastoralists who depend on fresh cow’s milk as a staple food. However, the arid climate and a lack of clean water challenge milk production and conventional milk hygiene practices. By conducting informational interviews in eight Parakuyo Maasai regions and 13 districts of Tanzania we sought to identify the key indigenous plants preferred and establish their traditional manner of use. A semi-structured questionnaire was designed to: (i) determine the plants used, (ii) the parts used, (iii) methods of preparation and utensil smoking, (iv) therapeutic applications and associated health benefits of these plants, and (v) alternative uses; that may suggest why they are used and preferred. Twenty plants were identified as being the most valuable, comprising predominantly hard wood trees and shrubs with strong aromas and astringent tastes suggestive of a role played by secondary metabolites. The most frequently mentioned plants, in order of preference, were: Zanthoxylum chalybeum (prickly ash; overall preference 26.6 %), Olea europaea subsp. africana (African wild olive; 11.9 %), Combretum molle (velvet bush willow; 11.4 %), Cordia ovalis/monoica (satin saucer berry; 9.5 %) and C. sinensis (oldoroko; 7.3 %). Many of these plants are also used medicinally by these pastoralists for a variety of infectious diseases, suggesting possible antimicrobial properties. Plant choices also tended to vary by local geography and the purpose to which the calabashes were assigned, e.g. old or new calabashes and milk stored for children or mothers. Nevertheless, the expertise of selecting these plants and their innovative applications is transmitted solely by the oral tradition. Further, climatic change is adversely affecting herbaceous habitats in these regions and inter-tribal territorial strife and land-grabs necessitate that the pastoralists remain nomadic. Unless we document and attempt to understand this old indigenous and sustainable hygiene know-how, it may be too late

FDG PET-CT demonstration of metastatic neuroendocrine tumor of prostate

which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background: FDG PET-CT is generally not suitable for diagnosing prostate cancer because of low glycolysis of the tumor cells. Neuroendocrine differentiation of the prostate cancer is often associated with early visceral metastasis and dismal prognosis, which is resulted from changed metabolic and regulatory pathways. Case presentation: A case is reported in this paper that FDG PET-CT demonstrates intense uptake of neuroendocrine tumor of the prostate and multiple metastases. Conclusion: There is high glycolysis and strong FDG-avidity of neuroendocrine tumor of the prostate, which is similar to that of high grade of neuroendocrine tumor in other tissue and organs. In some selected cases of prostate neuroendocrine cancer, whole body FDG PET-CT may be helpful for detection of metastatic disease. Background Positron emission tomography (PET) is a new imaging modality which has been widely used for detection o

Fluid Status in Peritoneal Dialysis Patients: The European Body Composition Monitoring (EuroBCM) Study Cohort

BACKGROUND: Euvolemia is an important adequacy parameter in peritoneal dialysis (PD) patients. However, accurate tools to evaluate volume status in clinical practice and data on volume status in PD patients as compared to healthy population, and the associated factors, have not been available so far. METHODS: We used a bio-impedance spectroscopy device, the Body Composition Monitor (BCM) to assess volume status in a cross-sectional cohort of prevalent PD patients in different European countries. The results were compared to an age and gender matched healthy population. RESULTS: Only 40% out of 639 patients from 28 centres in 6 countries were normovolemic. Severe fluid overload was present in 25.2%. There was a wide scatter in the relation between blood pressure and volume status. In a multivariate analysis in the subgroup of patients from countries with unrestricted availability of all PD modalities and fluid types, older age, male gender, lower serum albumin, lower BMI, diabetes, higher systolic blood pressure, and use of at least one exchange per day with the highest hypertonic glucose were associated with higher relative tissue hydration. Neither urinary output nor ultrafiltration, PD fluid type or PD modality were retained in the model (total R² of the model = 0.57). CONCLUSIONS: The EuroBCM study demonstrates some interesting issues regarding volume status in PD. As in HD patients, hypervolemia is a frequent condition in PD patients and blood pressure can be a misleading clinical tool to evaluate volume status. To monitor fluid balance, not only fluid output but also dietary input should be considered. Close monitoring of volume status, a correct dialysis prescription adapted to the needs of the patient and dietary measures seem to be warranted to avoid hypervolemia

Advice on testing the null hypothesis that a sample is drawn from a Normal distribution.

The Normal distribution remains the most widely-used statistical model, so it is only natural that researchers will frequently be required to consider whether a sample of data appears to have been drawn from a Normal distribution. Commonly-used statistical packages offer a range of alternative formal statistical tests of the null hypothesis of Normality, with inference being drawn on the basis of a calculated p-value. Here we aim to review the statistical literature on the performance of these tests, and briefly survey current usage of them in recently-published papers, with a view to offering advice on good practice. We find that authors in animal behaviour seem to be using such testing most commonly in situations where it is inadvisable (or at best unnecessary) involving pre-testing to select parametric or not-parametric analyses; and making little use of it in model-fitting situations where it might be of value. Of the many alternative tests, we recommend the routine use of either the Shapiro-Wilk or Chen-Shapiro tests; these are almost always superior to commonly-used alternatives like the Kolmogorov-Smirnov test, often by a substantial margin. We describe how both our recommend tests can be implemented. In contrast to current practice as indicated by our survey, we recommend that the results of these tests are reported in more detail (providing both the calculated sample statistic and the associated p-value). Finally, emphasize that even the higher-performing tests of Normality have low power (generally below 0.5 and often much lower) when sample sizes are less than 50, as is often the case in our field. Keywords: Gaussian distribution, parametric statistics, Schapiro-Wilk test, statistics, statistical powe

Quality and Safety Aspects of Infant Nutrition

Quality and safety aspects of infant nutrition are of key importance for child health, but oftentimes they do not get much attention by health care professionals whose interest tends to focus on functional benefits of early nutrition. Unbalanced diets and harmful food components induce particularly high risks for untoward effects in infants because of their rapid growth, high nutrient needs, and their typical dependence on only one or few foods during the first months of life. The concepts, standards and practices that relate to infant food quality and safety were discussed at a scientific workshop organized by the Child Health Foundation and the Early Nutrition Academy jointly with the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, and a summary is provided here. The participants reviewed past and current issues on quality and safety, the role of different stakeholders, and recommendations to avert future issues. It was concluded that a high level of quality and safety is currently achieved, but this is no reason for complacency. The food industry carries the primary responsibility for the safety and suitability of their products, including the quality of composition, raw materials and production processes. Introduction of new or modified products should be preceded by a thorough science based review of suitability and safety by an independent authority. Food safety events should be managed on an international basis. Global collaboration of food producers, food-safety authorities, paediatricians and scientists is needed to efficiently exchange information and to best protect public health. Copyright (C) 2012 S. Karger AG, Base

Arcanobacterium phocae infection in mink (Neovison vison), seals (Phoca vitulina, Halichoerus grypus) and otters (Lutra lutra)

Abstract Background Infectious skin disorders are not uncommon in mink. Such disorders are important as they have a negative impact on animal health and welfare as well as on the quality and value of the fur. This study presents the isolation of Arcanobacterium phocae from mink with severe skin lesions and other pathological conditions, and from wild seals and otters. Results In 2015, A. phocae was isolated for the first time in Denmark from outbreaks of dermatitis in mink farms. The outbreaks affected at least 12 farms. Originating from these 12 farms, 23 animals cultured positive for A. phocae. The main clinical findings were necrotizing pododermatitis or dermatitis located to other body sites, such as the lumbar and cervical regions. A. phocae could be isolated from skin lesions and in nine animals also from liver, spleen and lung, indicating a systemic spread. The bacterium was also, for the first time in Denmark, detected in dead seals (n = 9) (lungs, throat or wounds) and otters (n = 2) (throat and foot). Conclusions An infectious skin disorder in mink associated with A. phocae has started to occur in Danish farmed mink. The origin of the infection has not been identified and it is still not clear what the pathogenesis or the port of entry for A. phocae infections are

Digital Work Design

Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)More and more academic studies and practitioner reports claim that human work is increasingly disrupted or even determined by information and communication technology (ICT) (Cascio and Montealegre 2016). This will make a considerable share of jobs currently performed by humans susceptible to automation (e.g., Frey and Osborne 2017; Manyika et al. 2017). These reports often sketch a picture of ‘machines taking over’ traditional domains like manufacturing, while ICT advances and capabilities seem to decide companies’ fate. Consequently, ICT is often put at the core of innovative efforts. While this applies to nearly all areas of workplace design, a recent popular example of increasing technology centricity is ‘Industry 4.0’, which is often delineated as ‘machines talking to computers’

Virulence and antimicrobial resistance determinants of verotoxigenic Escherichia coli (VTEC) and of ESBL-producing multidrug resistant E. coli from foods of animal origin illegally imported to Europe

Microbial risk due to illegal food import has not been investigated so far. Here we aimed to reveal frequency, phenotype and genotype of verotoxigenic E. coli (VTEC) and ESBL-producing multidrug resistant (MDR) E. coli isolated from foods of animal origin confiscated at the EU airport borders. Of the 1500 food samples confiscated at the airports of Austria, Germany and Slovenia, the most frequent were cheese and meat products primarily from Turkey and from Balkan countries. The VTEC bacteria were isolated using ISO 16654:2001 for O157 and Ridascreen® ELISA based PCR testing of stx genes or ISO/ TS13136 for non-O157 VTEC, resulting in 15 isolates of VTEC (1%). In addition 600 samples from the Vienna airport were also tested for ESBL-producing MDR E. coli, using cefotaxime-McConkey agar. We identified 14 E. coli strains as ESBL/MDR E. coli. (0,9%) for phenotyping for antimicrobial resistance and for genotypiing by microarray (Identibac®,AMR05). The 15 VTEC isolates were phenotyped as Stx toxin producing non-O157 strain. Only one isolate, from Turkish cheese, proved to be EHEC (O26:H46). The remaining 14 strains represent uncommon VTEC serotypes with stx1 and/or stx2 genes. Microarray analysis (Identibac®, Ec03) revealed a wide range of other non-LEE encoding virulence genes. Pulsed field electrophoresis (PFGE) showed high genetic diversity of the strains. Multilocus sequence typing (MLST) established three new ST types (ST4505, 4506 and 4507) in the MLST database, and indicated the existence of 5 small clusters with no relation to origin or serotype/genotype of the strains, but representing several human-related ST types. All VTEC isolates were sensitive to 18 antimicrobials relevant to human and/or animal health, and did not contain resistance genes. ESB/MDR E. coli were resistant to at least 3 classes of antimicrobials. Microarray analysis detected TEM-1 in all but one strain and a variety of genes encoding resistances to other ESBLs (CTXM-1, OXA-1), trimethromprim, tetracycline, aminoglycosides and class1/class2 integrons (8/14 isolates). E.coli virulence microarray detected 2-6 virulence genes in all but one MDR E. coli, and one of the strains qualified as an atypical EPEC . Even though the frequency and attributes of isolated VTEC and ESBL/MDR E. coli did not represent an immediate major risk through illegal food import for the countries involved, it is suggested that the unusual serovars of VTEC as well as the virulence and antimicrobial resistance determinants of ESBL/MDR E. coli detected here, may indicate a future emerging threat by strains in illegally imported foods. Acknowledgement is due to: EU FP7 PROMISE (Grant No: 265877), to Dr. Mária Herpay, National Institute for Epidemiology, Budapest