144 research outputs found

    I, Robot, You, Consumer: Measuring Artificial Intelligence Types and their Effect on Consumers Emotions in Service

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    This research draws upon the increasing usage of AI in service. It aims at understanding the extent to which AI systems have multiple intelligence types like humans and if these types arouse different emotions in consumers. To this end, the research uses a two-study approach: Study 1 builds and evaluates a scale for measuring different AI intelligence types. Study 2 evaluates consumers’ emotional responses to the different AI intelligences. The findings provide a measurement scale for evaluating different types of artificial intelligence against human ones, thus showing that artificial intelligences are configurable, describable, and measurable (Study 1), and influence positive and negative consumers’ emotions (Study 2). The findings also demonstrate that consumers display different emotions, in terms of happiness, excitement, enthusiasm, pride, inspiration, sadness, fear, anger, shame, and anxiety, and also emotional attachment, satisfaction, and usage intention when interacting with the different types of AI intelligences. Our scale builds upon human intelligence against AI intelligence characteristics while providing a guidance for future development of AI-based systems more similar to human intelligences

    A construal level view of contemporary heritage tourism

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    Psychological distance is “a subjective experience that something is close or far away from the self, here, and now” (Trope & Liberman 2010, p. 440). This research investigates heritage tourism from the perspective of Construal Level theory, which postulates that individuals mentally represent objects and events by adopting either low or high construal levels. We show that heritage tourism leads tourists to adopt a higher psychological distance and therefore a higher construal level. In turn, this higher construal negatively affects destination loyalty and perceived uniqueness. However, authenticity and engagement moderate the heritage–construal relationship, counterbalancing the higher psychological distance induced by heritage. We explore these relationships in two studies focusing on contemporary heritage sites. This further allows to compare visitors’ mental representations of the experience, based on their memory type. The paper concludes by addressing implications for theory and practice

    It’s Not Just a Game: Virtual Edgework and Subjective Well-Being in E-Sports

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    The authors investigate subjective well-being in the context of e-sports (competitive video games). They adopt the theoretical lenses of virtual edgework theory, a recent adaptation of edgework theory from physical to digital contexts. Sports have long been used as a tool to improve subjective well-being. The research question is whether e-sports lead to well-being, as their physical sport counterparts do, and through what psychological mechanisms. The authors answer through a conceptual model of moderated mediation tested on hundreds of e-sports players. They also address the role of privacy concerns, as e-sports pose several potential threats to players' privacy that could hinder players' achievement of well-being. Findings suggest that virtual edgework provides a useful theoretical perspective for understanding consumers' behavior in digital environments. They also show that e-sports can lead to well-being by achieving feelings of self-enhancement under the positive moderation of perceived control over the digital environment and the negative moderation of privacy concerns

    Competing during a pandemic? Retailers’ ups and downs during the COVID-19 outbreak

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    The COVID-19 pandemic (that started in early 2020) is causing several disruptions in the short- and mid-term, to which businesses have to adapt. Some retailers have reacted to the emergency immediately, displaying a plethora of different intervention types. The authors aim to synthesize the challenges that retailers are facing during the COVID-19 emergency. We do this from the perspective of both consumers and managers, with the goal of providing guidelines on and examples of how retailers can handle this unprecedented situation

    Stereodivergent Synthesis of 5-Aminopipecolic Acids and Application in the Preparation of a Cyclic RGD Peptidomimetic as a nanomolar αVβ3 Integrin Ligand

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    A stereodivergent strategy was devised to obtain enantiopure cis and trans 5-aminopipecolic acids (5-APAs) in suitably protected forms to be employed in peptide synthesis as conformationally constrained \u3b1- and \u3b4-amino acids. The cis isomer was used as a \u3b4-amino acid to construct a cyclic RGD-containing peptidomimetic, the ability of which to compete with biotinylated vitronectin for the binding to the isolated \u3b1V\u3b23 integrin was measured (IC50 = 4.2 \ub1 0.9 nM). A complete 1H NMR and computational conformational analysis was performed to elucidate the reasons for the high affinity of this cyclic peptidomimetic in comparison with Cilengitide

    Epidemiologic aspects of closed-globe trauma

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    Purpose: To describe the epidemiologic aspects of closed-globe injury with contusion and its alterations. Methods: Forty patients with closed-globe injury, were analyzed prospectively between January 1998 and February 1999. They were attended at the Ocular Trauma Outpatient Clinic of the Department of Ophthalmology of the Escola Paulista de Medicina-Federal University of São Paulo. A complete ophthalmologic examination was performed in all patients and they were classified according to the new classification proposed by Pieramici et al (1997). Results: Sixty-seven and a half percent (67.5%) of the studied patients were less than 30 years old. The main causes were: accidents at home and acts of violence with 32.5% each. In relation to visual acuity, with best correction, 60.0% of the patients did not achieve 20/100 visual acuity. Seventy-five per cent (75.0%) showed improvement in visual acuity during follow-up and most in less than 1 month. Fifty-two and a half percent (52.5%) were classified as zone III. Fifty percent (50%) of the patients developed hyphema and 67.5% had some grade of angle recession, higher than 180° in 30.0%. Conclusions: In relation the patients attended at the Ocular Trauma Outpatient Clinic of the Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM), more than 13 years old, males, with closed-globe injury we may conclude: 1. it is more prevalent in adults; 2. the main causes were domestic accidents and violence (32.5% each); 3. it presents good visual acuity recovery, except for zone III patients; 4. fifty per cent developed hyphema; 5. more than a half had angle recession (67.5%) and 30.0% had angle recession over 180°.Objetivo: Descrever os aspectos epidemiológicos do traumatismo ocular fechado com contusão e suas alterações. Métodos: Foram avaliados, prospectivamente, 40 olhos de 40 pacientes, com idade superior a 13 anos, do sexo masculino, com traumatismo ocular fechado contuso, no período de janeiro de 1998 a fevereiro de 1999, atendidos no Ambulatório de Trauma Ocular do Departamento de Oftalmologia da Escola Paulista de Medicina-Universidade Federal de São Paulo (UNIFESP). Todos foram submetidos a exame oftalmológico completo e classificados de acordo com a nova classificação proposta por Pieramici et al. (1997). Resultados: Sessenta e sete e meio por cento (67,5%) dos pacientes tinham menos de 30 anos. As principais causas de traumatismo ocular contuso foram acidentes domésticos e violência com 32,5% cada. Em relação à acuidade visual, medida com a melhor correção, 60,0% apresentaram acuidade menor que 20/100 e 75,0% melhora da acuidade visual durante o acompanhamento, sendo que a maioria evoluiu com melhora em menos de 1 mês. Cinqüenta e dois e meio por cento (52,5%) foram classificados como zona III. Cinqüenta por cento (50%) dos pacientes evoluíram com hifema e 67,5% com algum grau de recessão angular, sendo 30% maior que 180°. Conclusões: Em relação aos pacientes atendidos no Ambulatório de Trauma Ocular da Universidade Federal do Estado de São Paulo - Escola Paulista de Medicina com idade menor de 13 anos e sexo masculino, com traumatismo ocular contuso podemos concluir que: 1. apresentou maior prevalência no adulto jovem; 2. as principais causas foram: acidentes domésticos e violência (32,5% cada); 3. apresenta boa recuperação da acuidade visual, exceto os pacientes zona III; 4. cinqüenta por cento evoluiu com hifema; 5. mais da metade, 67,5% apresentaram algum grau de recessão angular, sendo 30,0% maior que 180°.UNIFESP Departamento de OftalmologiaUNIFESP Departamento de Oftalmologia setor de Pronto Socorro e Trauma OcularUNIFESP, Depto. de OftalmologiaUNIFESP, Depto. de Oftalmologia setor de Pronto Socorro e Trauma OcularSciEL

    Evaluation of Androgen Receptor in Relation to Estrogen Receptor (AR/ER) and Progesterone Receptor (AR/PgR): A New Must in Breast Cancer?

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    Steroid nuclear receptors are known to be involved in the regulation of epithelial-mesenchymal transition process with important roles in invasion and metastasis initiation. Androgen receptor (AR) has been extensively studied, but its role in relation to breast cancer patient prognosis remains to be clarified. AR/ER ratio has been reported to be an unfavorable prognostic marker in early primary breast cancer, but its role in the patients with advanced disease has to be cleared. We retrospectively analyzed ER, PgR, and AR expression on a case series of 159 specimens of primary BC samples by using immunohistochemistry and 89 patients of these had luminal tumors for which AR and ER expression and survival data were available. For twenty-four patients both primary and metastatic tumors were available. A significantly shorter overall survival was observed in primary tumors with AR/PgR ratio 65 1.54 (HR = 2.27; 95% CI 1.30-3.97; p = 0.004). Similarly OS was significantly shorter when ER/PgR ratio 652 in primary tumors (HR = 1.89; 95% CI 1.10-3.24; p = 0.021). The analysis of the 24 patients who had biomarker determinations both in primary tumors and metastasis showed a better OS when AR/ER ratio in the metastasis was 65 0.90 (p = 0.022). Patients with a high AR/ER ratio in primary tumor that remained high in the metastasis had better prognosis in terms of OS (p = 0.011). Despite we suggested that the ratios AR/ER and AR/PgR could be used to identify patients with different prognosis, their real value needs to be better clarified in different BC settings through prospective studies
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