The Onset of Planet Formation in Brown Dwarf Disks

The onset of planet formation in protoplanetary disks is marked by the growth and crystallization of sub-micron-sized dust grains accompanied by dust settling toward the disk mid-plane. Here we present infrared spectra of disks around brown dwarfs and brown dwarf candidates. We show that all three processes occur in such cool disks in a way similar or identical to that in disks around low- and intermediate-mass stars. These results indicate that the onset of planet formation extends to disks around brown dwarfs, suggesting that planet formation is a robust process occurring in most young circumstellar disks.Comment: Published in Science 2005, vol 310, 834; 3 pages in final format, 4 figures + 8 pages Supporting Online Material. For final typeset, see http://www.sciencemag.org/cgi/content/abstract/310/5749/834?eto

The effect of local optically thick regions in the long-wave emission of young circumstellar disks

Multi-wavelength observations of protoplanetary disks in the sub-millimeter continuum have measured spectral indices values which are significantly lower than what is found in the diffuse interstellar medium. Under the assumption that mm-wave emission of disks is mostly optically thin, these data have been generally interpreted as evidence for the presence of mm/cm-sized pebbles in the disk outer regions. In this work we investigate the effect of possible local optically thick regions on the mm-wave emission of protoplanetary disks without mm/cm-sized grains. A significant local increase of the optical depth in the disk can be caused by the concentration of solid particles, as predicted to result from a variety of proposed physical mechanisms. We calculate the filling factors and implied overdensities these optically thick regions would need to significantly affect the millimeter fluxes of disks, and we discuss their plausibility. We find that optically thick regions characterized by relatively small filling factors can reproduce the mm-data of young disks without requesting emission from mm/cm-sized pebbles. However, these optically thick regions require dust overdensities much larger than what predicted by any of the physical processes proposed in the literature to drive the concentration of solids. We find that only for the most massive disks it is possible and plausible to imagine that the presence of optically thick regions in the disk is responsible for the low measured values of the mm spectral index. For the majority of the disk population, optically thin emission from a population of large mm-sized grains remains the most plausible explanation. The results of this analysis further strengthen the scenario for which the measured low spectral indices of protoplanetary disks at mm wavelengths are due to the presence of large mm/cm-sized pebbles in the disk outer regions.Comment: 13 pages, 2 figures, A&A in pres

Large grains in the disk of CQ Tau

We present 7mm observations of the dusty disk surrounding the 10 Myr old 1.5 Msun pre-main-sequence star CQ Tauri obtained at the Very Large Array with 0.8 arcsecond resolution and 0.1 mJy rms sensitivity. These observations resolve the 7mm emission in approximately the north-south direction, confirming previous results obtained with lower resolution. We use a two-layer flared disk model to interpret the observed fluxes from 7mm to 1.3mm together with the resolved 7mm structure. We find that the disk radius is constrained to the range 100 to 300 AU, depending on the steepness of the disk surface density distribution. The power law index of the dust opacity coefficient, beta, is constrained to be 0.5 to 0.7. Since the models indicate that the disk is optically thin at millimeter wavelengths for radii greater than 8 AU, the contribution of an optically thick region to the emission is less than 10%. This implies that high optical depth or complex disk geometry cannot be the cause of the observed shallow millimeter spectral index. Instead, the new analysis supports the earlier suggestion that dust particles in the disk have grown to sizes as large as a few centimeters. The dust in the CQ Tauri system appears to be evolved much like that in the TW Hydra system, a well-studied pre-main-sequence star of similar age and lower mass. The survival of gas-rich disks with incomplete grain evolution at such old ages deserves further investigations.Comment: A&A in press, 7 pages, 5 figure

T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva (TM)): Mechanisms of action

Psoriasis is a chronic, incurable, auto-immune disorder with cutaneous manifestations. New evidence on the central role of the immune system in the pathogenesis of psoriasis increasingly provides insight into pathogenic steps that can be modulated to provide disease control. Numerous biological therapies are in various stages of clinical development, with expectation of providing enhanced safety and efficacy over currently available psoriasis therapies. Efalizumab, a recombinant humanized monoclonal IgG1 antibody, is a novel targeted T-cell modulator that inhibits multiple steps in the immune cascade that result in the production and maintenance of psoriatic plaques, including initial T-cell activation and T-cell trafficking into sites of inflammation, including psoriatic skin, with subsequent reactivation in these sites. This article reviews the pharmacodynamic, pharmacokinetic and clinical effects observed during phase I, II and III efalizumab trials in patients with moderate to severe chronic plaque psoriasis. Copyright (C) 2004 S. Karger AG, Basel

Connection between jets, winds and accretion in T Tauri stars: the X-shooter view

We have analysed the [OI]6300 A line in a sample of 131 young stars with discs in the Lupus, Chamaeleon and signa Orionis star forming regions, observed with the X-shooter spectrograph at VLT. The stars have mass accretion rates spanning from 10^{-12} to 10^{-7} Mo/yr. The line profile was deconvolved into a low velocity component (LVC, 40 km/s ), originating from slow winds and high velocity jets, respectively. The LVC is by far the most frequent component, with a detection rate of 77%, while only 30% of sources have a HVC. The [OI]6300 luminosity of both the LVC and HVC, when detected, correlates with stellar and accretion parameters of the central sources (i.e. Lstar , Mstar , Lacc , Macc), with similar slopes for the two components. The line luminosity correlates better with the accretion luminosity than with the stellar luminosity or stellar mass. We suggest that accretion is the main drivers for the line excitation and that MHD disc-winds are at the origin of both components. In the sub-sample of Lupus sources observed with ALMA a relationship is found between the HVC peak velocity and the outer disc inclination angle, as expected if the HVC traces jets ejected perpendicularly to the disc plane. Mass loss rates measured from the HVC span from ~ 10^{-13} to ~10^{-7} Mo/yr. The corresponding Mloss/Macc ratio ranges from ~0.01 to ~0.5, with an average value of 0.07. However, considering the upper limits on the HVC, we infer a ratio < 0.03 in more than 40% of sources. We argue that most of these sources might lack the physical conditions needed for an efficient magneto-centrifugal acceleration in the star-disc interaction region. Systematic observations of populations of younger stars, that is, class 0/I, are needed to explore how the frequency and role of jets evolve during the pre-main sequence phase.Comment: 15 pages, 14 figures, Accepted for publication in A&

Grain growth and dust settling in a brown dwarf disk: Gemini/T-ReCS observations of CFHT-BD-Tau 4

We present accurate mid-infrared observations of the disk around the young, bona-fide brown dwarf CFHT-BD-Tau 4. We report GEMINI/T-ReCS measurements in the 7.9, 10.4 and 12.3 micron filters, from which we infer the presence of a prominent, broad silicate emission feature. The shape of the silicate feature is dominated by emission from 2 micron amorphous olivine grains. Such grains, being an order of magnitude larger than those in the interstellar medium, are a first proof of dust processing and grain growth in disks around brown dwarfs. The object's spectral energy distribution is below the prediction of the classical flared disk model but higher than that of the two-layer flat disk. A good match can be achieved by using an intermediate disk model with strongly reduced but non-zero flaring. Grain growth and dust settling processes provide a natural explanation for this disk geometry and we argue that such intermediate flaring might explain the observations of several other brown dwarf disks as well.Comment: Accepted for publication in Astronomy & Astrophysics Letters, 4.5 pages with 1 figur

The circumstellar environment of HD50138 revealed by VLTI/AMBER at high angular resolution

HD50138 is a Herbig B[e] star with a circumstellar disc detected at IR and mm wavelength. Its brightness makes it a good candidate for NIR interferometry observations. We aim to resolve, spatially and spectrally, the continuum and hydrogen emission lines in the 2.12-2.47 micron region, to shed light on the immediate circumstellar environment of the star. VLTI/AMBER K-band observations provide spectra, visibilities, differential phases, and closure phases along three long baselines for the continuum, and HI emission in Br$\gamma$ and five high-n Pfund lines. By computing the pure-line visibilities, we derive the angular size of the different line-emitting regions. A simple LTE model was created to constrain the physical conditions of HI emitting region. The continuum region cannot be reproduced by a geometrical 2D elongated Gaussian fitting model. We estimate the size of the region to be 1 au. We find the Br$\gamma$ and Pfund lines come from a more compact region of size 0.4 au. The Br$\gamma$ line exhibits an S-shaped differential phase, indicative of rotation. The continuum and Br$\gamma$ line closure phase show offsets of $\sim$-25$\pm$5 $^o$ and 20$\pm$10$^o$, respectively. This is evidence of an asymmetry in their origin, but with opposing directions. We find that we cannot converge on constraints for the HI physical parameters without a more detailed model. Our analysis reveals that HD50138 hosts a complex circumstellar environment. Its continuum emission cannot be reproduced by a simple disc brightness distribution. Similarly, several components must be evoked to reproduce the interferometric observables within the Br$\gamma$, line. Combining the spectroscopic and interferometric data of the Br$\gamma$ and Pfund lines favours an origin in a wind region with a large opening angle. Finally, our results point to an evolved source.Comment: accepted for publication in A&

The IC1396N proto-cluster at a scale of 250 AU

We investigate the mm-morphology of IC1396N with unprecedented spatial resolution to analyze its dust and molecular gas properties, and draw comparisons with objects of similar mass. We have carried out sensitive observations in the most extended configurations of the IRAM Plateau de Bure interferometer, to map the thermal dust emission at 3.3 and 1.3mm, and the emission from the $J$=13$_k\to12_k$ hyperfine transitions of methyl cyanide (CH$_3$CN). We unveil the existence of a sub-cluster of hot cores in IC1396N, distributed in a direction perpendicular to the emanating outflow. The cores are embedded in a common envelope of extended and diffuse dust emission. We find striking differences in the dust properties of the cores ($\beta\simeq$ 0) and the surrounding envelope ($\beta\simeq$ 1), very likely testifying to differences in the formation and processing of dust material. The CH$_3$CN emission peaks towards the most massive hot core and is marginally extended in the outflow direction

Exploring the dimming event of RW Aur A through multi-epoch VLT/X-Shooter spectroscopy

RW Aur A is a CTTS that has suddenly undergone three major dimming events since 2010. We aim to understand the dimming properties, examine accretion variability, and derive the physical properties of the inner disc traced by the CO ro-vibrational emission at NIR wavelengths (2.3 mic). We compared two epochs of X-Shooter observations, during and after the dimming. We modelled the rarely detected CO bandhead emission in both epochs to examine whether the inner disc properties had changed. The SED was used to derive the extinction properties of the dimmed spectrum and compare the infrared excess between the two epochs. Lines tracing accretion were used to derive the mass accretion rate in both states. The CO originates from a region with physical properties of T=3000 K, N$_{CO}$=1x10$^{21}$ cm$^{-2}$ and vsini=113 km/s. The extinction properties of the dimming layer were derived with the effective optical depth ranging from teff 2.5-1.5 from the UV to the NIR. The inferred mass accretion rate Macc is $1.5x 10^{-8}$ Msun/yr and $\sim 2x 10^{-8}$ Msun/yr after and during the dimming respectively. By fitting the SED, additional emission is observed in the IR during the dimming event from dust grains with temperatures of 500-700K. The physical conditions traced by the CO are similar for both epochs, indicating that the inner gaseous disc properties do not change during the dimming events. The extinction curve is flatter than that of the ISM, and large grains of a few hundred microns are thus required. When we correct for the observed extinction, Macc is constant in the two epochs, suggesting that the accretion is stable and therefore does not cause the dimming. The additional hot emission in the NIR is located at about 0.5 au from the star. The dimming events could be due to a dust-laden wind, a severe puffing-up of the inner rim, or a perturbation caused by the recent star-disc encounter.Comment: Accepted by Astronomy & Astrophysic

Verbal communication disorders in brain damaged post-stroke patients in Benin

AbstractIn Western countries, progress has lessened the severity of numerous sequels of verbal communication disorders (VCD). For Africa and more particularly Benin, few data on the subject are presently available.ObjectiveTo analyze the occurrence and development of post-stroke VCD in Benin.MethodA retrospective, descriptive and analytical study focused on 563 post-stroke patients treated in rehabilitation department of the National university hospital of Cotonou (CNHU) from January 2006 through December 2010.ResultsVCD prevalence was 42.10%. Average age was 57.17±12.62years, sex ratio was 1.75, and 74.69% were right-handed. VCD affected oral expression (95.78%), written expression (2.11%), oral comprehension (13.08%) and written comprehension or reading (0.84%). Type of stroke, sex and age had no impact on VCD occurrence following stroke. Only 5.91% of the patients underwent speech therapy. Progression was favorable in 21.09% of the cases studied.ConclusionIn Benin, post-stroke VCD is exceedingly common and occasions major social difficulties. Prevalence of VCD in a predominantly oral culture underscores the need for speech therapists to develop a more broadly ecological approach toward treatment