Within- and between-pen transmission of Classical Swine Fever Virus: a new method to estimate the basic reproduction ratio from transmission experiments

We present a method to estimate basic reproduction ratio R0 from transmission experiments. By using previously published data of experiments with Classical Swine Fever Virus more extensively, we obtained smaller confidence intervals than the martingale method used in the original papers. Moreover, our method allows simultaneous estimation of a reproduction ratio within pens R0w and a modified reproduction ratio between pens R'0b. Resulting estimates of R0w and R'0b for weaner pigs were 100 (95% CI 54.4-186) and 7.77 (4.68-12.9), respectively. For slaughter pigs they were 15.5 (6.20-38.7) and 3.39 (1.54-7.45), respectively. We believe, because of the smaller confidence intervals we were able to obtain, that the method presented here is better suited for use in future experiments

Malaria and land use: a spatial and temporal risk analysis in Southern Sri Lanka

Malaria / Waterborne diseases / Disease vectors / Land use / Water use / GIS / Statistical analysis / Risks / Mapping / Public health / Sri Lanka / Uda Walawe / Thanamalvila / Embilipitiya

Nutzung von Pflanzenextrakten zur Kontrolle der Krautfäule (P. infestans) im ökologischen Kartoffelbau

Der Befall mit dem Erreger der Kraut- und Knollenfäule (P. infestans) hat durch frühzeitigen Verlust der Assimilationsfläche regelmäßig erhebliche Ertragsverluste im Ökologischen Kartoffelbau zur Folge. Neben einer Reihe von vorbeugenden Maßnahmen, inbesondere Wahl toleranter Sorten und Vorkeimen des Pflanzgutes (KARALUS 1995, MEINCK 1999), sind zur direkten effizienten Kontrolle derzeit nur Kupferverbindungen zugelassen. Ein weitgehend unerforschtes Potential zur Kontrolle dieses Oomyceten liegt in der Nutzung von Pflanzenextrakten, diese Wirkung wurde in Feldversuchen untersucht

Роль інтелектуальної культури в процесі професійної підготовки майбутнього фахівця

Зниження рівня професійної підготовки фахівців у вищих навчальних закладах сьогодні є актуальною проблемою вищої освіти на всьому пострадянському просторі. І не в останню чергу ця проблема пов’язується з рівнем інтелекту студентської молоді

Влияние электромагнитного состояния турбоагрегата на работоспособность его узлов. Диагностика, демагнитезация

Рассмотрены условия возникновения электроэрозионных повреждений узлов турбоагрегатов, а так же их характерные признаки. Даны рекомендации по диагностике и устранению электроэрозии на турбоагрегатах находящихся в эксплуатации. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/21587There considered conditions resulting in occurring electroerozion damage sites in turbine unit, as well as their characteristic features. There given recommendations concerning diagnosis and elimination of electroerozion on turbine units being in operation. При цитировании документа, используйте ссылку http://essuir.sumdu.edu.ua/handle/123456789/2158

Семантика имен и поэтика их перечислений

Описаны факторы, влияющие на содержательность и эстетическую значимость перечислений поэтонимов в художественных текстах. На ряде примеров из творчества А. С. Пушкина представлены перемены, происходящие в совокупной семантике и поэтике рядов собственных имен в различных контекстах. Показаны некоторые теоретически возможные модели реализации "списков" поэтонимов. Намечены пути дальнейшего изучения художественно значимых перечислений.Обговорюються фактори, які впливають на змістовність та естетичну значущість перерахувань поет онімів у художніх текстах. На низці прикладів з творчості О.С. Пушкіна представлені зміни, які відбуваються у сукупній семантиці й поетиці рядів власних імен у різноманітних контекстах. Показані деякі теоретичні можливості моделювання переліків онімів. Накреслені шляхи подальшого вивчення художньо значимих переліків онімів.The factors which influence pithiness and the aesthetic inventory of poetonyms in art texts are described. On a number of examples from Pushkin works the changes occurring in cumulative semantics and poetics of numbers of proper names in various contexts are presented. Some theoretically possible models of realization of "lists" of onyms are shown. Ways of the further studying of artily significant transfers are planned

Cure of Helicobacter pylori infection in patients with reflux oesophagitis treated with long term omeprazole reverses gastritis without exacerbation of reflux disease: results of a randomised controlled trial

BACKGROUND: Helicobacter pylori gastritis may progress to glandular atrophy and intestinal metaplasia, conditions that predispose to gastric cancer. Profound suppression of gastric acid is associated with increased severity of H pylori gastritis. This prospective randomised study aimed to investigate whether H pylori eradication can influence gastritis and its sequelae during long term omeprazole therapy for gastro-oesophageal reflux disease (GORD). METHODS: A total of 231 H pylori positive GORD patients who had been treated for > or =12 months with omeprazole maintenance therapy (OM) were randomised to either continuation of OM (OM only; n = 120) or OM plus a one week course of omeprazole, amoxycillin, and clarithromycin (OM triple; n = 111). Endoscopy with standardised biopsy sampling as well as symptom evaluation were performed at baseline and after one and two years. Gastritis was assessed according to the Sydney classification system for activity, inflammation, atrophy, intestinal metaplasia, and H pylori density. RESULTS: Corpus gastritis activity at entry was moderate or severe in 50% and 55% of the OM only and OM triple groups, respectively. In the OM triple group, H pylori was eradicated in 90 (88%) patients, and activity and inflammation decreased substantially in both the antrum and corpus (p<0.001, baseline v two years). Atrophic gastritis also improved in the corpus (p<0.001) but not in the antrum. In the 83 OM only patients with continuing infection, there was no change in antral and corpus gastritis activity or atrophy, but inflammation increased (p<0.01). H pylori eradication did not alter the dose of omeprazole required, or reflux symptoms. CONCLUSIONS: Most H pylori positive GORD patients have a corpus predominant pangastritis during omeprazole maintenance therapy. Eradication of H pylori eliminates gastric mucosal inflammation and induces regression of corpus glandular atrophy. H pylori eradication did not worsen reflux disease or lead to a need for increased omeprazole maintenance dose. We therefore recommend eradication of H pylori in GORD patients receiving long term acid suppression

Updated cost-effectiveness and risk-benefit analysis of two infant rotavirus vaccination strategies in a high-income, low-endemic setting.

Since 2013, a biennial rotavirus pattern has emerged in the Netherlands with alternating high and low endemic years and a nearly 50% reduction in rotavirus hospitalization rates overall, while infant rotavirus vaccination has remained below 1% throughout. As the rotavirus vaccination cost-effectiveness and risk-benefit ratio in high-income settings is highly influenced by the total rotavirus disease burden, we re-evaluated two infant vaccination strategies, taking into account this recent change in rotavirus epidemiology

Machine Learning in Automated Text Categorization

The automated categorization (or classification) of texts into predefined categories has witnessed a booming interest in the last ten years, due to the increased availability of documents in digital form and the ensuing need to organize them. In the research community the dominant approach to this problem is based on machine learning techniques: a general inductive process automatically builds a classifier by learning, from a set of preclassified documents, the characteristics of the categories. The advantages of this approach over the knowledge engineering approach (consisting in the manual definition of a classifier by domain experts) are a very good effectiveness, considerable savings in terms of expert manpower, and straightforward portability to different domains. This survey discusses the main approaches to text categorization that fall within the machine learning paradigm. We will discuss in detail issues pertaining to three different problems, namely document representation, classifier construction, and classifier evaluation.Comment: Accepted for publication on ACM Computing Survey