Finite size effects on calorimetric cooperativity of two-state proteins

Finite size effects on the calorimetric cooperatity of the folding-unfolding transition in two-state proteins are considered using the Go lattice models with and without side chains. We show that for models without side chains a dimensionless measure of calorimetric cooperativity kappa2 defined as the ratio of the van't Hoff to calorimetric enthalpy does not depend on the number of amino acids N. The average value of kappa2 is about 3/4 which is lower than the experimental value kappa2=1. For models with side chains kappa2 approaches unity as kappa2 \sim N^mu, where exponent mu=0.17. Above the critical chain length Nc =135 these models can mimic the truly all-or-non folding-unfolding transition.Comment: 3 eps figures. To appear in the special issue of Physica

Optical qubit generation by state truncation using an experimentally feasible scheme

Generation of arbitrary superposition of vacuum and one-photon states using quantum scissors device (QSD) is studied. The device allows the preparation of states by truncating an input coherent light. Optimum values of the intensity of the coherent light for the generation of any desired state using the experimentally feasible QSD scheme are found.Comment: 8 pages, 4 figure

Evidence for a Mid-Atomic-Number Atmosphere in the Neutron Star 1E1207.4-5209

Recently Sanwal et al. (2002) reported the first clear detection of absorption features in an isolated neutron star, 1E1207.4-5209. Remarkably their spectral modeling demonstrates that the atmosphere cannot be Hydrogen. They speculated that the neutron star atmosphere is indicative of ionized Helium in an ultra-strong (~1.5x10^{14} G) magnetic field. We have applied our recently developed atomic model (Mori & Hailey 2002) for strongly-magnetized neutron star atmospheres to this problem. We find that this model, along with some simp le atomic physics arguments, severely constrains the possible composition of the atmosphere. In particular we find that the absorption features are naturally associated with He-like Oxygen or Neon in a magnetic field of ~10^{12} G, comparable to the magnetic field derived from the spin parameters of the neutron star. This interpretation is consistent with the relative line strengths and widths and is robust. Our model predicts possible substructure in the spectral features, which has now been reported by XMM-Newton (Mereghetti et al. 2002). However we show the Mereghetti et al. claim that the atmosphere is Iron or some comparable high-Z element at ~ 10^{12} G is easily ruled out by the Chandra and XMM-Newton data.Comment: 5 pages, AASTeX, Revised version. Accepted for publication in ApJ Letter

All the World Wide Web's a Stage: Improving students' information skills with dramatic video tutorials

Cataloged from PDF version of article.Purpose – The purpose of this article is to describe a collaborative project organised by Bilkent University Library, Turkey, to produce a series of instructional videos that are both informative and entertaining and also serve to market the library. Design/methodology/approach – The paper will outline the theoretical basis for the use of videos for library instruction, especially with reference to the habits and preferences of so-called Generation Y students and to the potential value of video for facilitating memory and learning. Findings – The use of humorous and interesting content, in a dramatised style, were found to improve Generation Y students’ learning and enjoyment of instructional videos. Practical implications – The development of the project demonstrates the practical and marketing benefits of collaboration by academic librarians with students and faculty. However, it proved more difficult to evaluate the efficiency of the final product in terms of influencing the attitude of students toward the library and library resources and thereby changing their behaviour when studying. Originality/value – The authors recommend that such library videos should definitely form part of an academic library’s information literacy programme, but should not constitute the sole element

Effect of wood aging on wine mineral composition and 87Sr/86Sr isotopic ratio

The evolution of mineral composition and wine strontium isotopic ratio 87Sr/86Sr (Sr IR) during wood aging were investigated. A red wine was aged in stainless steel tanks with French oak staves (Quercus sessiliflora Salisb.), with three industrial scale replicates. Sampling was carried out after 30, 60, and 90 days of aging, and the wines were evaluated in terms of general analysis, phenolic composition, total polysaccharides, multielement composition, and Sr IR. Li, Be, Mg, Al, Sc, Ti, V, Mn, Co, Ni, Cu, Zn, Ga, Ge, As, Rb, Sr, Y, Zr, Mo, Sb, Cs, Ba, Pr, Nd, Sm, Eu, Dy, Ho, Er, Yb, Lu, Tl, and Pb elements and 87Sr/86Sr were determined by quadrupole inductively coupled plasma mass spectrometry (Q-ICP-MS) and Na, K, Ca, and Fe by flame atomic absorption spectrometry (FAAS). Two-way ANOVA was applied to assess wood aging and time effect on Sr IR and mineral composition. Wood aging resulted in significantly higher concentrations of Mg, V, Co, Ni, and Sr. At the end of the aging period, wine exhibited statistically identical Sr IR compared to control. Study suggests that wood aging does not affect 87Sr/86Sr, not precluding the use of this parameter for wine traceability purposesinfo:eu-repo/semantics/publishedVersio

Finite size effects on thermal denaturation of globular proteins

Finite size effects on the cooperative thermal denaturation of proteins are considered. A dimensionless measure of cooperativity, Omega, scales as N^zeta, where N is the number of amino acids. Surprisingly, we find that zeta is universal with zeta = 1 + gamma, where the exponent gamma characterizes the divergence of the susceptibility for a self-avoiding walk. Our lattice model simulations and experimental data are consistent with the theory. Our finding rationalizes the marginal stability of proteins and substantiates the earlier predictions that the efficient folding of two-state proteins requires the folding transition temperature to be close to the collapse temperature.Comment: 3 figures. Physical Review Letters (in press

Stabilization of Extra Dimensions at Tree Level

By considering the effects of string winding and momentum modes on a time dependent background, we find a method by which six compact dimensions become stabilized naturally at the self-dual radius while three dimensions grow large.Comment: 15 pages, 2 figures, minor typos correcte

On Winding Branes and Cosmological Evolution of Extra Dimensions in String Theory

We consider evolution of compact extra dimensions in cosmology and try to see whether wrapped branes can prevent the expansion of the internal space. Some difficulties of Brandenberger and Vafa mechanism for decompactification are pointed out. In both pure Einstein and dilaton gravities, we study cosmology of winding brane gases in a continuum approximation. The energy momentum tensor is obtained by coupling the brane action to the gravity action and we present several exact solutions for various brane configurations. T-duality invariance of the solutions are established in dilaton gravity. Our results indicate that phenomenologically the most viable scenario can be realized when there is only one brane wrapping over all extra dimensions.Comment: 17 pages, RevTex4, 2 figures, a paragraph added, to appear in Classical and Quantum Gravit