Dynamic compensation in the central Pacific Ocean

The intermediate-wavelength geoid (lambda similar to 2000 km) and sea-floor topography fields in the central Pacific Ocean were studied in terms of static and dynamic compensation models. Topographic features on the sea-floor with lambda less than 1000 km were found to be compensated both regionally, by the elastic strength of the lithosphere, and locally, by displacing mantle material to reach isostatic adjustment. The larger-scale sea-floor topography and the corresponding geoid anomalies with lambda similar to 2000 km cannot be explained by either local or regional compensation. The topography and the resulting geoid anomaly at this wavelength were modeled by considering the dynamic effects arising from viscous stresses in a layer of fluid with a highly temperature-dependent viscosity for the cases of: (1) surface cooling, and (2) basal heating. In this model, the mechanical properties of the elastic part of the lithosphere were taken into account by considering an activation energy of about 520 kJ/mol in the Arrhenius law for the viscosity. Numerical predictions of the topography, total geoid anomaly, and admittance were obtained, and the results show that the thermal perturbation in the layer, which accounts for the mass deficit, must be located close to the surface to compensate the gravitational effect of the surface deformation. For the case of basal heating, the temperature dependence of viscosity results in a separation of the upper, quasi-rigid lid from the lower mobile fluid, hence inhibiting the development of a compensating thermal perturbation at shallow depths. The results clearly rule out small-scale, upper-mantle convection as the source of these anomalies. Instead, the geophysical observables can be well explained by a shallow, transient thermal perturbation

Lithospheric structure in the Pacific geoid

The high degree and order SEASAT geoid in the central Pacific correlates closely with the structure of the cooling lithosphere. Relative changes in plate age across major fracture zones in relatively young seafloor frame the east-west trending pattern formed by the geoid anomalies. The field removal in bathymetry corresponds to removal of some of the low degree and order geoidal components, the step like structure across fracture zones is also removed. The regional thermal subsidence was removed from the bathymetry by subtracting a mean subsidence surface from the observed bathymetry. This produces a residual bathymetry map analogous to the usual residual depth anomaly maps. The residual bathymetry obtained in this way contains shallow depths for young seafloor, and larger depths for older seafloor, thus retaining the structure of the lithosphere while removing the subsidence of the lithosphere

Estado del arte sobre la investigación en identidad organizacional

Working Paper del Departamento de Organización de Empreses de la Universitat Politècnica de Catalunya sobre la investigación en identidad organizacional.El estado del arte es una forma de aludir a lo que se sabe sobre una materia, lo que se ha dicho hasta el momento que ha sido más relevante. En este sentido la pretensión de este documento es situar al lector interesado en cuál es la situación de conocimiento actual sobre la identidad organizacional. Esta materia ha ido tomando relevancia en la investigación científica sobre dirección de empresas en los últimos años. De hecho, la identidad organizacional se ha revelado como un activo intangible de gran influencia en las organizaciones, hasta tal punto que su errónea evaluación o tratamiento puede conllevar graves repercusiones para la organización, incluso su desaparición. La identidad organizacional ha adquirido el interés científico, si bien los investigadores más relevantes en esta materia coinciden en que los trabajos de investigación no han alcanzado su culminación, más bien se encuentran en fases iniciales y animan a continuar investigando en este área de conocimiento.Preprin

Exploring the Impact of a Positive Psychology and Creative Journal Arts Intervention with Latina/o Adolescents

A creative journal arts and positive psychology intervention was utilized to explore resilience, personal recovery attitudes, and symptoms of depression in Latina/o adolescents. The impact of a seven-week group counseling experience conducted with adolescents was analyzed and revealed positive improvements for participants in all three areas. Benefits for Latina/o youth participating in this type of group are discussed and guidelines for school counselors and clinical mental health counselors are revealed

AN EXAMINATION OF THE STRUCTURE OF THE VOCATIONAL OUTCOME EXPECTATIONS SCALE WITH LATINA/O STUDENTS

In the current study, we investigated the psychometric properties of a meaningful measure of career development among Latina/o students. A confirmatory factor analysis (CFA) was used to evaluate structural validity of the Vocational Outcome Expectations scale. The results supported a modest one-factor structure for the VOE scale. Internal consistency was good as measured by coefficient alpha. Findings provide support for the reliability and validity of the VOE with Latina/o students. A discussion regarding the usefulness of this measure of career development is provided

Beyond platinum: synthesis, characterization, and in vitro toxicity of Cu(II)-releasing polymer nanoparticles for potential use as a drug delivery vector

The field of drug delivery focuses primarily on delivering small organic molecules or DNA/RNA as therapeutics and has largely ignored the potential for delivering catalytically active transition metal ions and complexes. The delivery of a variety of transition metals has potential for inducing apoptosis in targeted cells. The chief aims of this work were the development of a suitable delivery vector for a prototypical transition metal, Cu2+, and demonstration of the ability to impact cancer cell viability via exposure to such a Cu-loaded vector. Carboxylate-functionalized nanoparticles were synthesized by free radical polymerization and were subsequently loaded with Cu2+ via binding to particle-bound carboxylate functional groups. Cu loading and release were characterized via ICP MS, EDX, XPS, and elemental analysis. Results demonstrated that Cu could be loaded in high weight percent (up to 16 wt.%) and that Cu was released from the particles in a pH-dependent manner. Metal release was a function of both pH and the presence of competing ligands. The toxicity of the particles was measured in HeLa cells where reductions in cell viability greater than 95% were observed at high Cu loading. The combined pH sensitivity and significant toxicity make this copper delivery vector an excellent candidate for the targeted killing of disease cells when combined with an effective cellular targeting strategy

Resilience to social defeat stress in adolescent male mice

Adverse social experiences during adolescence are associated with the appearance of mental illness in adulthood. Social defeat (SD) is an ethologically valid murine model to study the consequences of social stress. In adolescent mice, SD induces depressive-like behaviors, increased anxiety and potentiates the reinforcing effects of cocaine and alcohol. However, not all mice exposed to SD will be susceptible to these effects. Adult mice resilient to the effects of SD show a consistent phenotype being resilient to depressive-like behaviors and to the increase in cocaine and alcohol consumption. The aim of the present study was to characterize the resilient phenotype to depressive-like behaviors and increase cocaine and ethanol rewarding effects of mice socially defeated during adolescence. To that end, adolescent mice were exposed to repeated SD, and 24 h after the last encounter, they underwent a social interaction test (SIT) in order to evaluate depressive-like behaviors. Cocaine-induced reward conditioning and ethanol intake was evaluated in two different sets of mice 3 weeks after the last SD using cocaine-induced conditioned place preference (CPP) and oral ethanol self-administration (SA). The neuroinflammation response was measured at the end of the experimental procedure by measuring striatal and cortical levels of IL-6 and CX3CL1. The results confirmed that a comparable percentage of adolescent mice develop resilience to depressive-like behaviors to that observed in adult mice. However, increased anxiety was more severe in resilient mice. Likewise, an increased preference for an ineffective dose of cocaine and an increased ethanol consumption was observed in resilient mice compared to controls. The increase in IL-6 and CX3CL1 was mainly observed in the striatum of susceptible mice compared to that of control mice. Our results confirm that, contrary to prior assumptions in adults, responses to SD stress are more complex and singular in adolescents, and caution should be taken for the correct interpretation and translation of those phenotypes

Introducing the Journal of Melittology: An outlet for disseminating bee research and raising melittological awareness

A new journal is introduced, the focus of which is to disseminate the results of research on wild and managed bees, to raise public awareness of bees, and to promote and facilitate international communication and collaboration