6,130 research outputs found
Grey-Box Model: An ensemble approach for addressing semi-supervised classification problems
In this paper, we propose a novel and interpretable grey-box ensemble using a selflabeled approach for semi-supervised classification problems. The prospective greybox ensembles a more interpretable whitebox model with a black-box technique. This scheme could guide the comparatively data expensive white-box component with the results from the more accurate black-box part. We evaluate the proposal in an inductive
learning setting showing good performance in partially labeled datasets
The massive multiple system HD 64315
The O6 Vn star HD 64315 is believed to belong to the star-forming region
known as NGC 2467, but previous distance estimates do not support this
association. We explore the multiple nature of this star with the aim of
determining its distance, and understanding its connection to NGC 2467. A total
of 52 high-resolution spectra have been gathered over a decade. We use their
analysis, in combination with the photometric data from All Sky Automated
Survey and Hipparcos catalogues, to conclude that HD 64315 is composed of at
least two spectroscopic binaries, one of which is an eclipsing binary. HD 64315
contains two binary systems, one of which is an eclipsing binary. The two
binaries are separated by 0.09 arcsec (or 500 AU) if the most likely distance
to the system, around 5 kpc, is considered. The presence of fainter companions
is not excluded by current observations. The non-eclipsing binary (HD 64315
AaAb) has a period of 2.70962901+/-0.00000021 d. Its components are hotter than
those of the eclipsing binary, and dominate the appearance of the system. The
eclipsing binary (HD 64315 BaBb) has a shorter period of 1.0189569+/-0.0000008
d. We derive masses of 14.6+-2.3 M for both components of the BaBb
system. They are almost identical; both stars are overfilling their respective
Roche lobes, and share a common envelope in an overcontact configuration. The
non-eclipsing binary is a detached system composed of two stars with spectral
types around O6 V with minimum masses of 10.8 M and 10.2 M, and
likely masses aprox. 30 M. HD 64315 provides a cautionary tale about
high-mass star isolation and multiplicity. Its total mass is likely above 90
M,but it seems to have formed without an accompanying cluster. It
contains one the most massive overcontact binaries known, a likely merger
progenitor in a very wide multiple system.Comment: 14 pages, 13 figures, 8 Table
Ventilatory settings in the initial 72Â h and their association with outcome in out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial
Purpose: The optimal ventilatory settings in patients after cardiac arrest and their association with outcome remain unclear. The aim of this study was to describe the ventilatory settings applied in the first 72 h of mechanical ventilation in patients after out-of-hospital cardiac arrest and their association with 6-month outcomes.
Methods: Preplanned sub-analysis of the Target Temperature Management-2 trial. Clinical outcomes were mortality and functional status (assessed by the Modified Rankin Scale) 6 months after randomization.
Results: A total of 1848 patients were included (mean age 64 [Standard Deviation, SD = 14] years). At 6 months, 950 (51%) patients were alive and 898 (49%) were dead. Median tidal volume (VT) was 7 (Interquartile range, IQR = 6.2-8.5) mL per Predicted Body Weight (PBW), positive end expiratory pressure (PEEP) was 7 (IQR = 5-9) cmH20, plateau pressure was 20 cmH20 (IQR = 17-23), driving pressure was 12 cmH20 (IQR = 10-15), mechanical power 16.2 J/min (IQR = 12.1-21.8), ventilatory ratio was 1.27 (IQR = 1.04-1.6), and respiratory rate was 17 breaths/minute (IQR = 14-20). Median partial pressure of oxygen was 87 mmHg (IQR = 75-105), and partial pressure of carbon dioxide was 40.5 mmHg (IQR = 36-45.7). Respiratory rate, driving pressure, and mechanical power were independently associated with 6-month mortality (omnibus p-values for their non-linear trajectories: p < 0.0001, p = 0.026, and p = 0.029, respectively). Respiratory rate and driving pressure were also independently associated with poor neurological outcome (odds ratio, OR = 1.035, 95% confidence interval, CI = 1.003-1.068, p = 0.030, and OR = 1.005, 95% CI = 1.001-1.036, p = 0.048). A composite formula calculated as [(4*driving pressure) + respiratory rate] was independently associated with mortality and poor neurological outcome.
Conclusions: Protective ventilation strategies are commonly applied in patients after cardiac arrest. Ventilator settings in the first 72 h after hospital admission, in particular driving pressure and respiratory rate, may influence 6-month outcomes
Shallow vs deep learning architectures for white matter lesion segmentation in the early stages of multiple sclerosis
In this work, we present a comparison of a shallow and a deep learning
architecture for the automated segmentation of white matter lesions in MR
images of multiple sclerosis patients. In particular, we train and test both
methods on early stage disease patients, to verify their performance in
challenging conditions, more similar to a clinical setting than what is
typically provided in multiple sclerosis segmentation challenges. Furthermore,
we evaluate a prototype naive combination of the two methods, which refines the
final segmentation. All methods were trained on 32 patients, and the evaluation
was performed on a pure test set of 73 cases. Results show low lesion-wise
false positives (30%) for the deep learning architecture, whereas the shallow
architecture yields the best Dice coefficient (63%) and volume difference
(19%). Combining both shallow and deep architectures further improves the
lesion-wise metrics (69% and 26% lesion-wise true and false positive rate,
respectively).Comment: Accepted to the MICCAI 2018 Brain Lesion (BrainLes) worksho
Reactivity Effects in a Very-High-Temperature Pebble-Bed Reactor
The very-high-temperature reactor (VHTR) is one of the most promising and innovative designs selected by the Generation IV International Forum. Although previous papers have focused on the study and optimization of several parameter of a VHTR conceptual design, there is still much work needed to achieve the commercial introduction of this technology. The primary aim of this study is to obtain the reactivity effects of such parameters as the temperature of the fuel, moderator, and reflector, and the poisoning by 135Xe and 149Sm in the VHTR critically. To reach this goal, the widely-used MCNP6 code was employed in order to simulate the neutronics of the VHTR. The viability of the utilization of the MCNP6 code and the developed model for the study of the physics of the VHTR core was confirmed through the calculation and comparison with benchmarks provided by the IAEA. Based on the results of the temperature coefficients of reactivity obtained, a negative reactivity effect on the system of about 12 pcm/K was found, as is expected in all the nuclear fission reactors, while the combined effect of fission products 135Xe and 149Sm implies a negative reactivity of 3475 pcm
Phenomenological constraints on Lemaitre-Tolman-Bondi cosmological inhomogeneities from solar system dynamics
We, first, analytically work out the long-term, i.e. averaged over one
orbital revolution, perturbations on the orbit of a test particle moving in a
local Fermi frame induced therein by the cosmological tidal effects of the
inhomogeneous Lemaitre-Tolman-Bondi (LTB) model. The LTB solution has recently
attracted attention, among other things, as a possible explanation of the
observed cosmic acceleration without resorting to dark energy. Then, we
phenomenologically constrain both the parameters K_1 = -\ddot R/R and K_2 =
-\ddot R^'/R^' of the LTB metric in the Fermi frame by using different kinds of
solar system data. The corrections to the standard
Newtonian/Einsteinian precessions of the perihelia of the inner planets
recently estimated with the EPM ephemerides, compared to our predictions for
them, yield K_1 = (4+8) 10^-26 s^-2, K_2 = (3+7) 10^-23 s^-2. The residuals of
the Cassini-based Earth-Saturn range, compared with the numerically integrated
LTB range signature, allow to obtain K_1/2 = 10^-27 s^-2. The LTB-induced
distortions of the orbit of a typical object of the Oort cloud with respect to
the commonly accepted Newtonian picture, based on the observations of the comet
showers from that remote region of the solar system, point towards K_1/2 <=
10^-30-10^-32 s^-2. Such figures have to be compared with those inferred from
cosmological data which are of the order of K1 \approx K2 = -4 10^-36 s^-2.Comment: LaTex2e, 18 pages, 3 tables, 3 figures. Minor changes. Reference
added. Accepted by Journal of Cosmology and Astroparticle Physics (JCAP
Integral Field Spectroscopy of the Central Regions of 3C 120: Evidence of a Past Merging Event
IFS combined with HST WFPC imaging were used to characterize the central
regions of the Seyfert 1 radio galaxy 3C 120. We carried out the analysis of
the data, deriving intensity maps of different emission lines and the continua
at different wavelengths from the observed spectra. Applying a 2D modeling to
the HST images we decoupled the nucleus and the host galaxy, and analyzed the
host morphology. The host is a highly distorted bulge dominated galaxy, rich in
substructures. We developed a new technique to model the IFS data extending the
2D modeling. Using this technique we separated the Seyfert nucleus and the host
galaxy spectra, and derived a residual data cube with spectral and spatial
information of the different structures in 3C 120. Three continuum-dominated
structures (named A, B, and C) and other three extended emission line regions
(EELRs, named E1, E2 and E3) are found in 3C 120 which does not follow the
general behavior of a bulge dominated galaxy. We also found shells in the
central kpc that may be remnants of a past merging event in this galaxy. The
origin of E1 is most probably due to the interaction of the radio-jet of 3C 120
with the intergalactic medium. Structures A, B, and the shell at the southeast
of the nucleus seem to correspond to a larger morphological clumpy structure
that may be a tidal tail, consequence of the past merging event. We found a
bright EELR (E2) in the innermost part of this tidal tail, nearby the nucleus,
which shows a high ionization level. The kinematics of the E2 region and its
connection to the tidal tail suggest that the tail has channeled gas from the
outer regions to the center.Comment: 55 pages, 18 figures and 5 tables Accepted by AP
Matching microscopic and macroscopic responses in glasses
We first reproduce on the Janus and Janus II computers a milestone experiment
that measures the spin-glass coherence length through the lowering of
free-energy barriers induced by the Zeeman effect. Secondly we determine the
scaling behavior that allows a quantitative analysis of a new experiment
reported in the companion Letter [S. Guchhait and R. Orbach, Phys. Rev. Lett.
118, 157203 (2017)]. The value of the coherence length estimated through the
analysis of microscopic correlation functions turns out to be quantitatively
consistent with its measurement through macroscopic response functions.
Further, non-linear susceptibilities, recently measured in glass-forming
liquids, scale as powers of the same microscopic length.Comment: 6 pages, 4 figure
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