Mantenimiento rutinario de carreteras “supervisión de carreteras pavimentadas” “concesión Ancón-Huacho-Pativilca”

En las dos últimas décadas, la Conservación de Carreteras y Gestión de Infraestructura Vial se ha convertido en un punto importante dentro del desarrollo de la infraestructura vial en el país. Incrementando el número de concesiones desde su inicio, 1993, con la “Concesión Arequipa – Matarani”, La Operación de carreteras contempla actividades en operaciones de peaje y pesaje, conservación y gestión de infraestructura vial, todas ellas en el marco de la seguridad vial, respeto del medio ambiente y bienestar de las comunidades aledañas a las zonas de trabajo, de acuerdo a los lineamientos establecidos por el estado a representado por el Ministerio de Transporte y Comunicaciones. El presente documento constituye un informe de experiencia profesional adquirida como ingeniero supervisor en la Concesión: “Red Vial 5 Ancón – Huacho – Pativilca “de la carretera Panamericana Norte. En las que se señala los aportes de una gestión eficiente en base a los conocimientos técnicos y manejo de recursos, las cuales deben regirse dentro del marco contractual. For the last two decades, the Conservation of Highways and Management of Road Infrastructure has become an important subject within the development of road infrastructure in the country. Increasing the number of concessions since its inception in 1993 and its first concession awarded being "Arequipa – Matarani". Highways Operation includes activities in road tolls and weighing operations, maintenance and management of road infrastructure, all in the context of road safety, respect for the environment and welfare of the communities surrounding the working areas, according to the guidelines established by the state and represented by the Ministry of Transport and Communications. The following document constitutes a report of professional knowledge acquired through work experience in engineering supervision for the Concession: "Red Vial 5 Ancón - Huacho - Pativilca" of the North Pan American Highway. In which it states the contributions of efficient management based on technical knowledge and resource management, which must be bound under the margins of contract.Trabajo de suficiencia profesiona

Enfermedad inflamatoria intestinal: depresión y estrategias de afrontamiento

Los objetivos de esta investigación fueron evaluar las estrategias de afrontamiento del estrés que utilizan los enfermos de Crohn y Colitis Ulcerosa una vez diagnosticada las enfermedad y relacionar estas estrategias con el estado de ánimo (depresivo - no depresivo), con el fin de determinar qué estrategias de afrontamiento son las que más están influyendo en el estado de ánimo del enfermo. La muestra estuvo formada por 40 pacientes, a los que se les administró un cuestionario demográfico, el Inventario de Depresión de Beck y el Cuestionario de Estrategias de Afrontamiento de Lazarus y Folkman. Los datos de este estudio reflejan que un alto porcentaje de enfermos de Crohn y Colitis Ulcerosa (45%) se encuentra deprimido, y que las diferencias en cuanto al sexo y la situación laboral son estadísticamente significativas, siendo las mujeres y aquellos pacientes que se encuentran desempleados, jubilados o que se dedican a sus labores los que mayor puntuación en depresión obtienen. Asimismo, la estrategia de afrontamiento que mejor predice un estado de ánimo depresivo es la de huida.The objectives of this research were to evaluate the stress coping strategies that Crohn and Ulcerative Colitis patients use once the illness is diagnosed and to relate these strategies with the mood (depressive - not depressive), with the aim of determining which coping strategies are influencing more in the patient mood. The sample was formed by 40 patients. They completed a demographic questionnaire, the Beck Depression Inventory and the Coping Strategies Questionnaire by Lazarus and Folkman. The data of this study reflect that a high percentage of Crohn and Ulcerative Colitis patients (45%) are depressed, and differences relating the sex and employed situation are statistically significant, being women and unemployed, retired or housewife patients who got a higher score in depression. Likewise, the coping strategy that better predicts the mood depression state is the avoidance

Cytochrome c signalosome in mitochondria

Cytochrome c delicately tilts the balance between cell life (respiration) and cell death (apoptosis). Whereas cell life is governed by transient electron transfer interactions of cytochrome c inside the mitochondria, the cytoplasmic adducts of cytochrome c that lead to cell death are amazingly stable. Interestingly, the contacts of cytochrome c with its counterparts shift from the area surrounding the heme crevice for the redox complexes to the opposite molecule side when the electron flow is not necessary. The cytochrome c signalosome shows a higher level of regulation by post-translational modifications—nitration and phosphorylation—of the hemeprotein. Understanding protein interfaces, as well as protein modifications, would puzzle the mitochondrial cytochrome c-controlled pathways out and enable the design of novel drugs to silence the action of pro-survival and pro-apoptotic partners of cytochrome c.Spanish Ministry of Science and Innovation BFU2009-07190Andalusian Government BIO198 P08-CVI-387

Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV

The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense debate, since altering it leads to cell aging and other related pathologies. Here, we discuss three current views-the so-called solid, fluid and plasticity models-which describe the organization of the main membrane-embedded mitochondrial protein complexes and the key elements that regulate and/or facilitate supercomplex assembly. The soluble electron carrier cytochrome c has recently emerged as an essential factor in the assembly and function of respiratory supercomplexes. In fact, a 'restricted diffusion pathway' mechanism for electron transfer between complexes III and IV has been proposed based on the secondary, distal binding sites for cytochrome c at its two membrane partners recently discovered. This channeling pathway facilitates the surfing of cytochrome c on both respiratory complexes, thereby tuning the efficiency of oxidative phosphorylation and diminishing the production of reactive oxygen species. The well-documented post-translational modifications of cytochrome c could further contribute to the rapid adjustment of electron flow in response to changing cellular conditions.Spanish Ministry of Economy and Competitiveness (BFU2015-71017/BMC MINECO/FEDER and PGC2018-096049-B-I00 BIO/BMC MICINN/FEDER, EU

Physical activity, body composition, physical fitness, and body dissatisfaction in physical education of Extremadura adolescents: an exploratory study

In recent years, physical activity levels among youths have declined significantly. This has led to a decline in adherence to physical activity recommendations. In this sense, physical education offers an ideal environment that contributes positively to improving adherence to physical activity recommendations, as it teaches students movement-related skills and knowledge. The objective of the present research was to investigate the relationship between physical activity levels, body composition, fitness in Physical Education, and body dissatisfaction levels, and to analyse sex differences in relation to the study variables. The sample was formed of 1166 participants from the 1st and 2nd secondary compulsory education, of which 642 were boys (age 13.16 ± 0.91), and 524 girls (age 13.08 ± 0.85). The measure of physical activity was the Physical Activity Questionnaire for Adolescents (PAQ-A). Body composition was assessed using weight and height to calculate their body mass index. Cardiorespiratory capacity was assessed using the Course-Navette test in Physical Education lessons. The results showed the relationship between physical activity and body mass index, cardiorespiratory capacity, and body satisfaction. It was also confirmed that higher levels of physical activity were associated with a lower body mass index, improvements in cardiorespiratory fitness, and lower levels of body dissatisfaction to a greater extent in boys than in girls. The study concludes that improvements in the study variables were associated with increased physical activity. In addition, it seems necessary to promote healthy lifestyles in physical education lessons, especially during adolescence, as they could serve as a gateway for the improvement of health-related fitness in future generations. Increasing the amount of physical activity among young people is vital. Therefore, it would be essential to develop intervention programs in physical education classes, especially during adolescence, aimed at promoting and increasing physical activity and its benefits

自我概念概况：在校儿童的身体满意度、体重指数和身体活动方面的差异

The aims of the present study has been to identify different groups of students, with homogeneous profiles, for the different dimensions that make up the physical self-concept, and to establish differences in relation to body dissatisfaction, body mass index, and physical activity. A total of 303 adolescents, male (150) and female (152), aged between 10-13 years (M = 11.74) belonging to different primary education centers participated in the study. The PSPP questionnaire was used for the evaluation of physical self-concept, Stunkard figures for body satisfaction, BMI, and the PAQ-A questionnaire for the evaluation of physical activity. Descriptive statistics, bivariate correlations, cluster analysis, and ANOVA of a factor were made to establish differences between the variables. The results showed the establishment of 4 different profiles in relation to the different dimensions of the physical self-concept. Likewise, significant differences were shown between BMI, physical activity, and body satisfaction between profiles derived from self-concept. As a conclusion, 4 different profiles are established regarding the dimensions of physical self-concept among which there are differences around BMI, levels of FA, and body satisfaction.El objetivo del presente estudio ha sido identificar diferentes grupos de estudiantes, con perfiles homogéneos, para las distintas dimensiones que componen el autoconcepto físico, y establecer diferencias en relación a la insatisfacción corporal, índice de masa corporal, y actividad física. Un total de 303 adolescentes, masculinos (150) y femeninos (152), con edades comprendidas entre los 10-13 años (M = 11.74) pertenecientes a diferentes centros de Educación Primaria participaron en el estudio. Se empleó el cuestionario PSPP para la valoración del autoconcepto físico, las figuras de Stunkard para la satisfacción corporal, el IMC, y el cuestionario PAQ-A para la valoración de la actividad física. Se realizaron estadísticosdescriptivos, correlaciones de bivariadas, analisis de cluster, y ANOVA de un factor para establecer diferencias entre las variables. Los resultados mostraron el establecimiento de 4 perfiles distintos en relación a las distintas dimensiones del autoconcepto físico. Asimismo, se mostraron diferencias significativas entre el IMC, la actividad física, y la satisfacción corporal entre los perfiles derivados del autoconcepto. A modo de conclusión se establecen 4 perfiles distintos respecto las dimensiones del autoconcepto físico entre las cuales existen diferencias en torno al IMC, niveles de AF, y satisfacción corporal.Целью настоящего исследования было выявить различные группы студентов с однородными профилями по различным измерениям, составляющим физическую самооценку, и установить различия в отношении неудовлетворенности телом, индекса массы тела и физической активности. В исследовании приняли участие 303 подростка мужского (150) и женского (152) пола в возрасте 10-13 лет (М = 11,74) из разных начальных школ. Для оценки физической самооценки использовался опросник PSPP, для оценки удовлетворенности телом - показатели Стункарда, ИМТ, для оценки физической активности - опросник PAQ-A. Для установления различий между переменными были проведены описательная статистика, двумерные корреляции, кластерный анализ и однофакторный ANOVA. Результаты показали наличие 4 различных профилей в отношении различных измерений физической самооценки. Также были обнаружены значительные различия между ИМТ, физической активностью и удовлетворенностью телом среди профилей, полученных на основе самооценки. В заключение, было установлено 4 различных профиля в отношении измерений физической самооценки, среди которых существуют различия по ИМТ, уровню ПА и удовлетворенности телом.本研究的目的是针对构成身体自我概念的不同维度，确定具有相同特征的不同学生群体，并确定与身体满意度、体重指数和身体活动方面有关的差异。共有 303 名青少年参与了研究，其中包括150名男性和152名女性，年龄在 10-13 岁 (M = 11.74)，在不同的小学上学。我们应用PSPP 问卷评估身体自我概念，Stunkard 数据用于评估身体满意度，BMI，PAQ-A 问卷用于评估身体活动。研究进行了描述性统计、双变量相关性、聚类分析和单向方差分析以确定变量之间的差异。研究结果根据与身体自我概念的不同维度将参与者分为4类。同样，BMI、身体活动和身体满意度在源自自我概念的概况之间也存在显着差异。作为结论，研究按照身体自我概念的维度将参与者分为4类，他们在BMI、PA水平和身体满意度方面存在差异

The prevalence of intraarticular associated lesions after acute acromioclavicular joint injuries is 20%. A systematic review and meta-analysis.

Purpose To synthesise the evidence on the prevalence of associated intraarticular lesions in subjects with acute acromioclavicular joint (ACJ) dislocations. Methods A search in two electronic databases (PUMBMED and EMBASE) was performed from 1985 to 2019. Two independent reviewers selected studies that complied with the following inclusion criteria: (1) the study included data on surgically treated ACJ dislocation grade III–V in the Rockwood classification, (2) the ACJ injuries were acute (the surgery was performed less than 6 weeks after injury), (3) an arthroscopic evaluation of the glenohumeral joint was performed during surgery. The quality of the studies included was assessed using the tool of the Joanna Briggs Institute. Results A total of 47 studies with acute ACJ injuries met the initial inclusion criteria. Of these, 21 studies (9 retrospective case series, 9 prospective case series and 3 retrospective cohort studies) presented data on associated intraarticular lesions amenable for use in the meta-analysis. The meta-analysed studies included a total of 860 subjects with acute ACJ dislocations with a male/female ratio of 6.5 and a mean age of 32 years. The meta-analysis showed a prevalence of associated intraarticular lesions in subjects with acute ACJ of 19.9% (95% confidence interval [CI] 14.0–26.4%; 21 studies, 860 analysed participants; P = 0.000; I2: 74.5% random-effects model; low risk of bias). Conclusion One in five subjects with surgically treated acute ACJ dislocations will have an associated intraarticular lesion that requires further intervention. The case for a customary arthroscopic evaluation of the joint, even when an open procedure is performed to deal with the ACJ dislocation, is strong.pre-print798 K

Sistema abierto de Televisión Digital Terrestre (TDT) accesible para personas con deficiencia visual

Este artículo detalla el diseño, implementación y validación de un sistema abierto de Televisión Digital accesible para personas con deficiencia visual. La solución facilita que este colectivo pueda acceder a los contenidos de la guía electrónica de programación recibidos a través de la TDT, pudiendo configurar a demanda la interfaz de usuario gráfica (IGU) y la síntesis de voz (TTS). Se presenta el análisis de sistemas existentes, requisitos demandados por este colectivo y tecnologías disponibles, tanto de TDT como de TTS, con el fin de elegir las más apropiadas con criterios de accesibilidad, interoperabilidad y bajo coste. Los resultados obtenidos en la investigación demuestran que el sistema desarrollado es congruente con los criterios del Diseño para Todos según constata la validación realizada. El sistema ofrece combinaciones de colores y fuentes (contraste, tamaño) para diferentes necesidades de la deficiencia visual, y utiliza TTS local y adaptable para las personas con ceguera

Generation of enhanced synthetic off-line signatures based on real on-line data

Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. M. Díaz-Cabrera, M. Gómez-Barrero, A. Morales, M. A. Ferrer, J. Galbally, "Generation of Enhanced Synthetic Off-Line Signatures Based on Real On-Line Data" in 14th International Conference on Frontiers in Handwriting Recognition (ICFHR), Heraklion (Greece), 2014, 482 - 487One of the main challenges of off-line signature verification is the absence of large databases. A possible alternative to overcome this problem is the generation of fully synthetic signature databases, not subject to legal or privacy concerns. In this paper we propose several approaches to the synthesis of off-line enhanced signatures from real dynamic information. These synthetic samples show a performance very similar to the one offered by real signatures, even increasing their discriminative power under the skilled forgeries scenario, one of the biggest challenges of handwriting recognition. Furthermore, the feasibility of synthetically increasing the enrolment sets is analysed, showing promising results.This work has been partially supported by projects: MICINN TEC2012-38630-C04-02, Contexts (S2009/TIC-1485) from CAM, Bio-Shield (TEC2012-34881) from Spanish MINECO, TABULA RASA (FP7-ICT-257289) and BEAT (FP7-SEC-284989) from EU, and Cátedra UAM-Telefónica

Planificación S-TDMA en redes submarinas de comunicaciones inalámbricas

Las redes submarinas de sensores son de importancia en la vigilancia y monitorización del medio submarino. Si se desea que las redes sean inalámbricas y con un alcance superior a unos pocos metros, las comunicaciones han de ser acústicas. El canal acústico submarino es de poca capacidad de transmisión y muy hostil en términos de ruido y desvanecimiento, ya que es selectivo en frecuencia. Además, estas redes inalámbricas plantean el problema añadido de la alimentación eléctrica. En redes de tráfico saturado, el procedimiento más eficiente de acceso al medio es TDMA espacial, por los menores “overheads” y la práctica ausencia de “handshaking”. En esta comunicación se presenta un procedimiento para la obtención de una planificación eficiente en redes submarinas de comunicaciones que utilicen TDMA espacial. El procedimiento está basado en dos algoritmos heurísticos encadenados y encuentra una planificación temporal eficiente para conseguir la misma cantidad de información de los sensores de cada nodo de la red.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec