Tra il regno di Napoli e la Francia. Viaggi scientifici, percorsi di formazione ed esilio tra la fine del Settecento e la prima metà dell'Ottocento

La ricerca analizza i rapporti scientifici tra il Sud d'Italia e la Francia tra la fine del XVIII secolo e la prima metà del XIX, considerando le missioni di ingegneri, di naturalisti e di medici. Nel regno di Napoli sono essenzialmente queste tre categorie di scienziati che hanno la possibilità di viaggiare e di raggiunre la Francia tra la fine del Settecento e la prima metà dell'Ottocento. Occorre comunque considerare che anche altri gruppi di uomini hanno contribuito a nutrire la rete delle relazioni e degli interscambi tra il regno di Napoli e la Francia. Bisogna infine aggiungere che le relazioni franco–napoletane non si sono costruite soltanto grazie agli spostamenti di uomini. La circolazione libraria, nonché la discussione all'Académie des sciences degli studi compiuti a Napoli e l'acquisto di strumenti scientifici presso i più rinomati artigiani parigini hanno rappresentato altri interessanti aspetti, che è stato indispensable approfondire, delle relazioni tra la Francia e il regno di Napoli

Mobile Computing in Digital Ecosystems: Design Issues and Challenges

In this paper we argue that the set of wireless, mobile devices (e.g., portable telephones, tablet PCs, GPS navigators, media players) commonly used by human users enables the construction of what we term a digital ecosystem, i.e., an ecosystem constructed out of so-called digital organisms (see below), that can foster the development of novel distributed services. In this context, a human user equipped with his/her own mobile devices, can be though of as a digital organism (DO), a subsystem characterized by a set of peculiar features and resources it can offer to the rest of the ecosystem for use from its peer DOs. The internal organization of the DO must address issues of management of its own resources, including power consumption. Inside the DO and among DOs, peer-to-peer interaction mechanisms can be conveniently deployed to favor resource sharing and data dissemination. Throughout this paper, we show that most of the solutions and technologies needed to construct a digital ecosystem are already available. What is still missing is a framework (i.e., mechanisms, protocols, services) that can support effectively the integration and cooperation of these technologies. In addition, in the following we show that that framework can be implemented as a middleware subsystem that enables novel and ubiquitous forms of computation and communication. Finally, in order to illustrate the effectiveness of our approach, we introduce some experimental results we have obtained from preliminary implementations of (parts of) that subsystem.Comment: Proceedings of the 7th International wireless Communications and Mobile Computing conference (IWCMC-2011), Emergency Management: Communication and Computing Platforms Worksho

Cooperação e autonomia : jogando em grupo e que se aprende

Orientador: João Batista FreireDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Educação FisicaResumo: O objetivo deste trabalho é analisar a contribuição que podem dar os jogos em grupo para uma prática pedagógica que esteja direcionada à construção da atitude cooperativa e da moral autônoma pelos alunos. O trabalho contém basicamente duas partes. A primeira denominada "a revelação de uma intenção" busca, por meio de uma revisão bibliográfica, responder a duas questões que nos fornecem subsídios teóricos para se trabalhar com os jogos em grupo na perspectiva de uma prática cooperativa. No primeiro capítulo a questão "por que educar para a cooperação?" nos abre um espaço para justificar a importância de se trabalhar com os conteúdos atitudinais na escola e acena com a co-operação como o procedimento mais fértil para uma educação moral autônoma. O segundo capítulo, centrado na questão "onde educar para a cooperação?", nos obriga a pensar no espaço de ação ideal para uma prática cooperativa entre os alunos e o professor durante as aulas de Educação Motora. Na segunda parte do trabalho, denominada "a proposição de uma ação", centramos nossos olhares na construção de uma proposta concreta de ação para o professor de Educação Motora que esteja disposto a educar para a cooperação através dos jogos. No terceiro capítulo, antes de pensarmos no "como fazer" investigamos o "como tem sido feito". Por meio da observação de crianças jogando nas aulas de Educação Física, analisamos alguns aspectos referentes à qualidade das relações que são estabelecidas entre as crianças e como o professor interfere no espaço do jogo para encaminhar as situações de conflito e confronto entre os alunos. Finalmente, no quarto capítulo com base na análise dos dados coletados, nos arriscamos a elaborar aquilo que chamamos de um "guia de intervenção qualificada" para a educação da atitude cooperativa através dos jogos. Respondendo à pergunta "como educar para a cooperação?", selecionamos alguns princípios pedagógicos que devem fazer parte de um programa de ensino que vislumbre fazer da Educação Motora e do jogo, um espaço de possível ajuda para a construção da atitude cooperativa e da moralidade autônomaAbstract: The main objective of this work is to analyze the contribution that games in group can eventually render to a pedagogical practice, which is directed to the construction of a cooperative attitude and moral autonomy of the students. The work contains basically two parts. The first, entitled "The revelation of an intention" tries, by means of a bibliographical revision, to answer two questions that supply theorical subsidies to work with games in group within the perspective of a cooperative practice. In the first chapter, the question "why educate for cooperation?¿ opens a space to justify the importance given when working with attitude contents in school, and visualizes cooperation as being the most fertile procedure when considering moral autonomy education. The second chapter, centered in the question "where to educate focusing on cooperation?" makes us think about the ideal action space for a cooperative practice among students and teacher during Motor Education classes. During the second part of the work, which was called "the proposition of an action", we centered our attention on the construction of a concrete action proposal for the teacher of Motor Education who is willing to educate towards cooperation by means of games. In the third chapter, before thinking about the "how to do", we investigated the "how it is done". After having observed children playing during Physical Education classes, we analyzed some aspects concerning the quality of the relationship established among the children and how the teacher interferes within the game space and is able to forward the conflict and confrontation situations among the students. Finally, in the fourth chapter based on the analysis of the collected data, we took the risk to precisely elaborate what we denominated as being" a qualified intervention guide", based on the education of cooperative attitude by means of games. Answering the question "how to educate for cooperation?" some basic pedagogical principles were selected and we strongly believe they must be part of a teaching program which should be focused on making Motor Education and Games, a space of possible and reliable assistance towards the construction of cooperative attitude and autonomous moralityMestradoEducação MotoraMestre em Educação Físic

Surgical treatment of an aseptic fistulized acromioclavicular joint cyst: a case report and review of the literature.

An acromioclavicular joint cyst is an uncommonly reported condition, which seems to result from a massive rotator cuff tear and degenerative osteoarthritis of the acromioclavicular joint. We present the case of an 81-year-old man affected by an acromioclavicular joint cyst, associated to a massive rotator cuff tear, proximal migration of the humeral head and osteoarthritis of the gleno-humeral joint. The mass was 7 x 2.5 cm in size and the overlying skin presented a fistula that drained clear synovial-like fluid. Plain X-ray examination of the left shoulder showed proximal migration of the humeral head migration and osteoarthritis of the gleno-humeral joint, and further MRI evaluation confirmed the clinical diagnosis of a complete rotator cuff tear and observed a large subcutaneous cyst in communication with the degenerative acromioclavicular joint. The patient underwent surgical excision of the cyst and lateral resection of the clavicle to prevent disease recurrence. To the best of our knowledge, this is the first reported case of an acromioclavicular joint cyst complicated by an aseptic fistula resulting from multiple aspirations

Measurement and Numerical Modeling of Cell-Free Protein Synthesis: Combinatorial Block-Variants of the PURE System

Protein synthesis is at the core of bottom-up construction of artificial cellular mimics. Intriguingly, several reports have revealed that when a transcription–translation (TX–TL) kit is encapsulated inside lipid vesicles (or water-in-oil droplets), high between-vesicles diversity is observed in terms of protein synthesis rate and yield. Stochastic solute partition can be a major determinant of these observations. In order to verify that the variation of TX–TL components concentration brings about a variation of produced protein rate and yield, here we directly measure the performances of the 'PURE system' TX–TL kit variants. We report and share the kinetic traces of the enhanced Green Fluorescent Protein (eGFP) synthesis in bulk aqueous phase, for 27 combinatorial block-variants. The eGFP production is a sensitive function of TX–TL components concentration in the explored concentration range. Providing direct evidence that protein synthesis yield and rate actually mirror the TX–TL composition, this study supports the above-mentioned hypothesis on stochastic solute partition, without excluding, however, the contribution of other factors (e.g., inactivation of components)

Extrinsic stochastic factors (solute partition) in gene expression inside lipid vesicles and lipid-stabilized water-in-oil droplets: a review

Abstract The encapsulation of transcription–translation (TX–TL) machinery inside lipid vesicles and water-in-oil droplets leads to the construction of cytomimetic systems (often called 'synthetic cells') for synthetic biology and origins-of-life research. A number of recent reports have shown that protein synthesis inside these microcompartments is highly diverse in terms of rate and amount of synthesized protein. Here, we discuss the role of extrinsic stochastic effects (i.e. solute partition phenomena) as relevant factors contributing to this pattern. We evidence and discuss cases where between-compartment diversity seems to exceed the expected theoretical values. The need of accurate determination of solute content inside individual vesicles or droplets is emphasized, aiming at validating or rejecting the predictions calculated from the standard fluctuations theory. At the same time, we promote the integration of experiments and stochastic modeling to reveal the details of solute encapsulation and intra-compartment reactions

Do prior intra-articular injections impact on the risk of periprosthetic joint infection in patients undergoing total hip arthroplasty? A meta-analysis of the current evidences with a focus on the timing of injection before surgery

Purpose: Intra-articular injection is a well-established and increasingly used treatment for the patient with mild-to-moderate hip osteoarthritis. The objectives of this literature review and meta-analysis are to evaluate the effect of prior intra-articular injections on the risk of periprosthetic joint infection (PJI) in patients undergoing total hip arthroplasty (THA) and to try to identify which is the minimum waiting time between hip injection and replacement in order to reduce the risk of infection. Methods: The database of PubMed, Embase, Google Scholar and Cochrane Library was systematically and independently searched, according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. To assess the potential risk of bias and the applicability of the evidence found in the primary studies to the review, the Newcastle-Ottawa scale (NOS) was used. The statistical analysis was performed by using the software 'R' version 4.2.2. Results: The pooling of data revealed an increased risk of PJI in the injection group that was statistically significative (P = 0.0427). In the attempt to identify a 'safe time interval' between the injection and the elective surgery, we conducted a further subgroup analysis: in the subgroup 0-3 months, we noted an increased risk of PJI after injection. Conclusions: Intra-articular injection is a procedure that may increase the risk of developing periprosthetic infection. This risk is higher if the injection is performed less than 3 months before hip replacement

Chapter HBIM e ICT. Il BIM per la valorizzazione della Fortezza Pisana di Marciana

The 43rd UID conference, held in Genova, takes up the theme of ‘Dialogues’ as practice and debate on many fundamental topics in our social life, especially in these complex and not yet resolved times. The city of Genova offers the opportunity to ponder on the value of comparison and on the possibilities for the community, naturally focused on the aspects that concern us, as professors, researchers, disseminators of knowledge, or on all the possibile meanings of the discipline of representation and its dialogue with ‘others’, which we have broadly catalogued in three macro areas: History, Semiotics, Science / Technology. Therefore, “dialogue” as a profitable exchange based on a common language, without which it is impossible to comprehend and understand one another; and the graphic sign that connotes the conference is the precise transcription of this concept: the title ‘translated’ into signs, derived from the visual alphabet designed for the visual identity of the UID since 2017. There are many topics which refer to three macro sessions: - Witnessing (signs and history) - Communicating (signs and semiotics) - Experimenting (signs and sciences) Thanks to the different points of view, an exceptional resource of our disciplinary area, we want to try to outline the prevailing theoretical-operational synergies, the collaborative lines of an instrumental nature, the recent updates of the repertoires of images that attest and nourish the relations among representation, history, semiotics, sciences