First generation of optical fiber phase reference distribution system for TESLA

This report describes the design of a phase stable Fiber Optic (FO) link for the TESLA technology based projects. The concept of this long optical link, with a feedback system suppressing long term drifts of the RF signal phase is described. Stability requirements are given and most important design issues affecting the system performance are discussed. The technical design issues of system components like laser transmitter and optical phase shifter are described in detail. Last sections depict the software developed for system control and experimental results obtained after system was assembled

Simulated Dynamics of Mixed Versus Uniform Grain Size Sediment Pulses in a Gravel-Bedded River

Mountain rivers often receive sediment in the form of episodic, discrete pulses from a variety of natural and anthropogenic processes. Once emplaced in the river, the movement of this sediment depends on flow, grain size distribution, and channel and network geometry. Here, we simulate downstream bed elevation changes that result from discrete inputs of sediment (10,000 m3), differing in volume and grain size distribution, under medium and high flow conditions. We specifically focus on comparing bed responses between mixed and uniform grain size sediment pulses. This work builds on a Lagrangian, bed-material sediment transport model and applies it to a 27 km reach of the mainstem Nisqually River, Washington, USA. We compare observed bed elevation change and accumulation rates in a downstream lake to simulation results. Then we investigate the magnitude, timing, and persistence of downstream changes due to the introduction of synthetic sediment pulses by comparing the results against a baseline condition (without pulse). Our findings suggest that bed response is primarily influenced by the sediment-pulse grain size and distribution. Intermediate mixed-size pulses (~50% of the median bed gravel size) are likely to have the largest downstream impact because finer sizes translate quickly and coarser sizes (median bed gravel size and larger) disperse slowly. Furthermore, a mixed-size pulse, with a smaller median grain size than the bed, increases bed mobility more than a uniform-size pulse. This work has important implications for river management, as it allows us to better understand fluvial geomorphic responses to variations in sediment supply

A systematic review of evidence for the psychometric properties of the Strengths and Difficulties Questionnaire

This paper synthesised evidence for the validity and reliability of the Strengths and Difficulties Questionnaire in children aged 3-5. A systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guidelines was carried out. Study quality was rated using the Consensus-based Standards for the Selection of Health Measurement Instruments. 41 studies were included (56 manuscripts). Two studies examined content and cultural validity, revealing issues with some questions. Six studies discussed language validations with changes to some wording recommended. There was good evidence for discriminative validity (Area Under the Curve ≥0.80), convergent validity (weighted average correlation coefficients ≥0.50, except for the Prosocial scale), and the 5-factor structural validity. There was limited support for discriminant validity. Sensitivity was below 70% and specificity above 70% in most studies that examined this. Internal consistency of the total difficulty scale was good (weighted average Cronbach’s alpha parents’ and teachers’ version 0.79 and 0.82) but weaker for other subscales (weighted average parents’ and teachers’ range 0.49-0.69 and 0.69-0.83). Inter-rater reliability between parents was moderate (correlation coefficients range 0.42-0.64) and between teachers strong (range 0.59-0.81). Cross-informant consistency was weak to moderate (weighted average correlation coefficients range 0.25-0.45). Test-retest reliability was mostly inadequate. In conclusion, the lack of evidence for cultural validity, criterion validity and test-retest reliability should be addressed given wide-spread implementation of the tool in routine clinical practice. The moderate level of consistency between different informants indicate that an assessment of a pre-schooler should not rely on a single informant

Experimental evaluation of sub-sampling IQ detection for low-level RF control in particle accelerator systems

The low-level radio frequency (LLRF) control system is one of the fundamental parts of a particle accelerator, ensuring the stability of the electro-magnetic (EM) field inside the resonant cavities. It leverages on the precise measurement of the field by in-phase/quadrature (IQ) detection of an RF probe signal from the cavities, usually performed using analogue downconversion. This approach requires a local oscillator (LO) and is subject to hardware non-idealities like mixer nonlinearity and long-term temperature drifts. In this work, we experimentally evaluate IQ detection by direct sampling for the LLRF system of the Polish free electron laser (PolFEL) now under development at the National Centre for Nuclear Research (NCBJ) in Poland. We study the impact of the sampling scheme and of the clock phase noise for a 1.3-GHz input sub-sampled by a 400-MSa/s analogue-to-digital converter (ADC), estimating amplitude and phase stability below 0.01% and nearly 0.01◦, respectively. The results are in line with state-of-the-art implementations, and demonstrate the feasibility of direct sampling for GHz-range LLRF systems

Developmental Exposure to Corn Grown on Lake Erie Dredged Material: A Preliminary Analysis

While corn is considered to be a healthy food option, common agricultural practices, such as the application of soil amendments, might be introducing contaminants of concern (COC) into corn plants. The use of dredged material, which contain contaminants such as heavy metals, polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs), as a soil amendment is increasing. Contaminants from these amendments can accumulate in corn kernels harvested from plants grown on these sediments and potentially biomagnify in organisms that consume them. The extent to which secondary exposure to such contaminants in corn affect the mammalian central nervous system has been virtually unexplored. In this preliminary study, we examine the effects of exposure to corn grown in dredge amended soil or a commercially available feed corn on behavior and hippocampal volume in male and female rats. Perinatal exposure to dredge-amended corn altered behavior in the open-field and object recognition tasks in adulthood. Additionally, dredge-amended corn led to a reduction in hippocampal volume in male but not female adult rats. These results suggest the need for future studies examining how dredge-amended crops and/or commercially available feed corn may be exposing animals to COC that can alter neurodevelopment in a sex-specific manner. This future work will provide insight into the potential long-term consequences of soil amendment practices on the brain and behavior

The head shaft angle is associated with hip displacement in children at GMFCS levels III-V - a population based study

Background:  An increased Head Shaft Angle (HSA) has been reported as a risk factor for hip displacement in children with cerebral palsy (CP) but opinions differ in the literature. The purpose of this study was to re-evaluate the relationship between HSA and hip displacement in a different population of children with CP. Methods:  The Cerebral Palsy Integrated Pathway Scotland surveillance programme includes 95% of all children with CP in Scotland. The pelvic radiographs from 640 children in GMFCS levels III-V were chosen. The most displaced hip was analysed and the radiographs used were those taken at the child’s first registration in the database to avoid the potential effects of surveillance on subsequent hip centration. A logistic regression model was used with hip displacement (migration percentage [MP] ≥40%) as outcome and HSA, GMFCS, age and sex as covariates. Results: The MP was ≥40% in 118 hips with a mean HSA of 164° (range 121–180°) and < 40% in 522 hips with a mean HSA of 160° (range 111–180°). The logistic regression analysis showed no significant influence of age and sex on MP in this population but a high GMFCS level was strongly associated with hip displacement. An increased HSA was also associated with hip displacement, a 10° difference in HSA for children adjusted for age, sex, and GMFCS gave an odds ratio of 1.26 for hip displacement equal or above 40% (p = 0.009) and hips with HSA above 164.5 degrees had an odds ratio of 1.96 compared with hips with HSA below 164.5 degrees (p = 0.002). Conclusion:  These findings confirm that HSA is associated with hip displacement in children in GMFCS levels III-V.Publisher PDFPeer reviewe

StreamLab Collaboratory: Experiments, Data Sets, and Research Synthesis

A series of community-led, large-scale laboratory experiments, termed “StreamLab”, were performed by the National Center for Earth-surface Dynamics (NCED) with the purpose of advancing multidisciplinary research, education, and knowledge transfer at the interface of physical/chemical/biological processes in streams, science-based stream restoration practice, and environmental sensing technologies. Two series of experiments, StreamLab06 and StreamLab08, were conducted in the Main Channel of the St. Anthony Falls Laboratory at the University of Minnesota, a flume 84 m long and 2.75 m wide with water fed by the Mississippi River at a rate of up to 8.5 m3/s. The purpose of this paper is to share with the broader community the data collected with the hope of stimulating further analysis and future experimental campaigns toward advancing our predictive understanding of the physical, chemical, and biological processes in streams. Toward this end, a brief summary of the results to date is included and some ideas for further research are provided

The Power of Environmental Observatories for Advancing Multidisciplinary Research, Outreach, and Decision Support: The Case of the Minnesota River Basin

An edited version of this paper was published by AGU. Copyright 2019 American Geophysical Union.Observatory‐scale data collection efforts allow unprecedented opportunities for integrative, multidisciplinary investigations in large, complex watersheds, which can affect management decisions and policy. Through the National Science Foundation‐funded REACH (REsilience under Accelerated CHange) project, in collaboration with the Intensively Managed Landscapes‐Critical Zone Observatory, we have collected a series of multidisciplinary data sets throughout the Minnesota River Basin in south‐central Minnesota, USA, a 43,400‐km2 tributary to the Upper Mississippi River. Postglacial incision within the Minnesota River valley created an erosional landscape highly responsive to hydrologic change, allowing for transdisciplinary research into the complex cascade of environmental changes that occur due to hydrology and land use alterations from intensive agricultural management and climate change. Data sets collected include water chemistry and biogeochemical data, geochemical fingerprinting of major sediment sources, high‐resolution monitoring of river bluff erosion, and repeat channel cross‐sectional and bathymetry data following major floods. The data collection efforts led to development of a series of integrative reduced complexity models that provide deeper insight into how water, sediment, and nutrients route and transform through a large channel network and respond to change. These models represent the culmination of efforts to integrate interdisciplinary data sets and science to gain new insights into watershed‐scale processes in order to advance management and decision making. The purpose of this paper is to present a synthesis of the data sets and models, disseminate them to the community for further research, and identify mechanisms used to expand the temporal and spatial extent of short‐term observatory‐scale data collection efforts

The Effects of Sodium Phosphate Supplementation on Physiological Responses to Submaximal Exercise and 20 km Cycling Time-Trial Performance

The aim of this study was to examine the effects of sodium phosphate (SP) supplementation on 26 physiological responses to submaximal exercise and 20 km cycling time-trial performance. Using a 27 randomised, double-blind, crossover design, 20 endurance-trained male cyclists (age: 31 ± 6 years; 28 height: 1.82 ± 0.07 m; body mass: 76.3 ± 7.0 kg; maximal oxygen uptake [V̇O2max]: 57.9 ± 5.5 mL·kg-29 1·min-1) completed two supplementation trials separated by a 14-day washout period. The trials 30 consisted of 10 minutes of cycling at 65% V̇O2max followed by a 20 km time-trial. Expired air was 31 monitored throughout each trial for the evaluation of V̇O2, minute ventilation (V̇E), and respiratory 32 exchange ratio (RER). Heart rate was monitored during each trial along with ratings of perceived 33 exertion (RPE) and blood lactate concentration. For four days before each trial, participants ingested 50 34 mg∙kg fat-free-mass-1·day-1 of either SP or placebo. There were no effects (p ≥ 0.05) of supplementation 35 on physiological responses during cycling at 65% V̇O2max. There were also no effects of 36 supplementation on time-trial performance (placebo: 32.8 ± 2.2 mins; SP: 32.8 ± 2.3 mins). 37 Nevertheless, relative to placebo, SP increased V̇E (mean difference: 3.81 L·min-1; 95% likely range: 38 0.16-7.46 L·min-1), RER (mean difference: 0.020; 95% likely range: 0.004-0.036), and RPE (mean 39 difference: 0.39; 95% likely range: 0.04-0.73) during time-trials; as well as post time-trial blood lactate 40 concentration (mean difference: 1.06 mmol·L-1; 95% likely range: 0.31-1.80 mmol·L-1). In conclusion, 41 SP supplementation has no significant effects on submaximal physiological responses or 20 km time-42 trial performance