165 research outputs found
Catch Shares in Action: Mexican Baja California FEDECOOP Benthic Species Territorial Use Rights for Fishing System
The Baja California Regional Federation of Fishing Cooperative Societies (FEDECOOP) is a groupallocated, area-based catch share, or Territorial Use Rights for Fishing (TURF), program. FEDECOOP consists of 13 fishing Cooperatives that collectively manage 10 TURFs to promote sustainable harvests, increase market access and power and provide stability to fishermen and fishing communities. The catch share program is a model for coordination across multiple Cooperatives and TURFs to achieve fishery goals. Key design features include voluntary no-take reserves to increase productivity and protect vulnerable fish species and the evolution of FEDECOOP to coordinate activities and provide services to multiple Cooperatives and TURFs
Catch Shares in Action: Mexican VigĂa Chico Cooperative Spiny Lobster Territorial Use Rights for Fishing Program
The Mexican Pescadores de VigĂa Chico Cooperative is a group-allocated, area-based catch share that manages the Punta Allen spiny lobster fishery. The catch share, or Territorial Use Rights for Fishing (TURF) program, includes a number of special design features to achieve goals set by the Mexican government and the Cooperative, including sustainable harvests and Cooperative self-sufficiency and self-governance. Important design features include a secure tenure length of 20 years with a strong assumption of renewal, clearly defined co-management responsibilities between the federal government and the Cooperative and the use of individual fishing zones developed by the Cooperative to maintain member accountability (Solares-Leal and Alvarez-Gil, 2003)
Limited Antigenic Diversity in Contemporary H7 Avian-Origin Influenza A Viruses from North America
Subtype H7 avianâorigin influenza A viruses (AIVs) have caused at least 500 confirmed human infections since 2003 and culling of \u3e75 million birds in recent years. Here we antigenically and genetically characterized 93 AIV isolates from North America (85 from migratory waterfowl [1976â2010], 7 from domestic poultry [1971â2012], and 1 from a seal [1980]). The hemagglutinin gene of these H7 viruses are separated from those from Eurasia. Gradual accumulation of nucleotide and amino acid substitutions was observed in the hemagglutinin of H7 AIVs from waterfowl and domestic poultry. Genotype characterization suggested that H7 AIVs in wild birds form diverse and transient internal gene constellations. Serologic analyses showed that the 93 isolates cross-reacted with each other to different extents. Antigenic cartography showed that the average antigenic distance among them was 1.14 units (standard deviation [SD], 0.57 unit) and that antigenic diversity among the H7 isolates we tested was limited. Our results suggest that the continuous genetic evolution has not led to significant antigenic diversity for H7 AIVs from North America. These findings add to our understanding of the natural history of IAVs and will inform public health decision-making regarding the threat these viruses pose to humans and poultry
Rock fracture grouting with microbially induced carbonate precipitation
Microbially induced carbonate precipitation has been proposed for soil stabilization, soil strengthening and permeability reduction as an alternative to traditional cement and chemical grouts. In this paper we evaluate the grouting of fine aperture rock fractures with calcium carbonate, precipitated through urea hydrolysis, by the bacteria Sporosarcina pasteurii. Calcium carbonate was precipitated within a small-scale and a near field-scale (3.1 m2) artificial fracture consisting of a rough rock lower surfaces and clear polycarbonate upper surfaces. The spatial distribution of the calcium carbonate precipitation was imaged using time-lapse photography and the influence on flow pathways revealed from tracer transport imaging. In the large-scale experiment, hydraulic aperture was reduced from 276 ÎŒm to 22 ÎŒm, corresponding to a transmissivity reduction of 1.71x10-5 m2/s to 8.75x10-9 m2/s, over a period of 12 days under constantly flowing conditions. With a modified injection strategy a similar three orders of magnitude reduction in transmissivity was achieved over a period of three days. Calcium carbonate precipitated over the entire artificial fracture with strong adhesion to both upper and lower surfaces and precipitation was controlled to prevent clogging of the injection well by manipulating the injection fluid velocity. These experiments demonstrate that microbially induced carbonate precipitation can successfully be used to grout a fracture under constantly flowing conditions and may be a viable alternative to cement based grouts when a high level of hydraulic sealing is required and chemical grouts when a more durable grout is required
Deep Supratentorial Extension is Associated with Poor Clinical Outcomes After Glioblastoma Resection
Introduction: Glioblastoma (GBM) often extends to deep supratentorial locations, which limits the extent of maximal safe resection. Deep supratentorial extension (DSE) may be a clinically convenient prognostic indicator following GBM resection.
Methods: 582 GBM resections from 2012-2018 were retrospectively reviewed. DSE was defined as tumoral extension to the basal ganglia, thalamus, corpus callosum, internal capsule, hypothalamus, caudate, or putamen as identified on preoperative imaging.
Results: DSE was identified in 32.9% cases (192), while 52.5% (306) involved only superficial supratentorial locations (frontal, parietal, temporal and occipital lobes). Within the DSE cohort, the most commonly affected anatomical locations were the corpus callosum (18.9%), basal ganglia (10.8%), and thalamus (5.5%). DSE was associated with a significantly higher rate of residual tumor (71.9%vs59.3%, p=.015), larger size (48.3 vs 43.6 mm, p=.007), and lower rate of radiological gross total resection (GTR) (55.6% vs 70.6%, p=.005). DSE was also associated with a worse progression free survival (PFS) (5.55vs8.32 months, p = .009) and overall survival (OS) (9.89vs14.23 months, p=.000). Kaplan-Meier curves showed worse OS with DSE (log rank=.003), and worse OS with involvement of 2+ DSE structures as compared to 1 or none (log rank=.000). DSE had no effect on OS among those achieving GTR (log rank=.626), but without GTR, DSE significantly worsened survival (log rank=.030) on Kaplan-Meier.
Discussion: DSE portended higher rates of residual tumor, lower rates of GTR, and worse PFS and OS, particularly among those not achieving GTR and with involvement of 2+ structures. DSE in GBM is a convenient and reliable negative prognostic factor
Effects of carrying a pregnancy and of method of delivery on urinary incontinence: a prospective cohort study
BACKGROUND: This study was carried out to identify risk factors associated with urinary incontinence in women three months after giving birth. METHODS: Urinary incontinence before and during pregnancy was assessed at study enrolment early in the third trimester. Incontinence was re-assessed three months postpartum. Logistic regression analysis was used to assess the role of maternal and obstetric factors in causing postpartum urinary incontinence. This prospective cohort study in 949 pregnant women in Quebec, Canada was nested within a randomised controlled trial of prenatal perineal massage. RESULTS: Postpartum urinary incontinence was increased with prepregnancy incontinence (adjusted odds ratio [adj0R] 6.44, 95% CI 4.15, 9.98), incontinence beginning during pregnancy (adjOR 1.93, 95% CI 1.32, 2.83), and higher prepregnancy body mass index (adjOR 1.07/unit of BMI, 95% CI 1.03,1.11). Caesarean section was highly protective (adjOR 0.27, 95% CI 0.14, 0.50). While there was a trend towards increasing incontinence with forceps delivery (adjOR 1.73, 95% CI 0.96, 3.13) this was not statistically significant. The weight of the baby, episiotomy, the length of the second stage of labour, and epidural analgesia were not predictive of urinary incontinence. Nor was prenatal perineal massage, the randomised controlled trial intervention. When the analysis was limited to women having their first vaginal birth, the same risk factors were important, with similar adjusted odds ratios. CONCLUSIONS: Urinary incontinence during pregnancy is extremely common, affecting over half of pregnant women. Urinary incontinence beginning during pregnancy roughly doubles the likelihood of urinary incontinence at 3 months postpartum, regardless whether delivery is vaginal or by Caesarean section
Congenital Hypothyroidism LongâTerm Followâup Project: Navigating the Rough Waters of a MultiâCenter, MultiâState Public Health Project
The Region 4 Midwest Genetics Collaborative, made up of seven regional states (Illinois, Indiana, Kentucky, Michigan, Minnesota, Ohio, and Wisconsin), brought together pediatric endocrinologists, state laboratory experts, public health followâup specialists, and parents of children with congenital hypothyroidism (CH) to identify the threeâyear followâup management and education patterns of primary care clinicians and pediatric endocrinologists in the care of children diagnosed with CH by state newborn screening (NBS) programs. Among a number of challenges, each state had different NBS methods, data systems, public health laws, and institutional review board (IRB) requirements. Furthermore, the diagnosis of CH was complicated by the timing of the NBS sample, the gestational age, weight, and coâmorbidities at delivery. There were 409 children with CH identified through NBS in 2007 in the seven state region. The clinician of record and the parents of these children were invited to participate in a voluntary survey. Approximately 64 % of clinician surveys were collected with responses to questions relating to treatment, monitoring practices, educational resources, genetic counseling, and services provided to children with confirmed CH and their families. Nearly oneâquarter (24 %) of parents surveyed responded to questions relating to treatment, education, genetic counseling, resources, and services they received or would like to receive. Deâidentified data from six of the seven states were compiled for analysis, with one state being unable to obtain IRB approval within the study timeline. The data from this collaborative effort will improve state followâup programs and aid in developing threeâyear followâup guidelines for children diagnosed with CH. To aid in the facilitation of similar public health studies, this manuscript highlights the challenges faced, and focuses on the pathway to a successful multiâstate public health endeavor.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147153/1/jgc40464.pd
Hydrodynamic coupling in microbially mediated fracture mineralization : formation of self-organized groundwater flow channels
Evidence of fossilized microorganisms embedded within mineral veins and mineral-filled fractures has been observed in a wide range of geological environments. Microorganisms can act as sites for mineral nucleation and also contribute to mineral precipitation by inducing local geochemical changes. In this study, we explore fundamental controls on microbially induced mineralization in rock fractures. Specifically, we systematically investigate the influence of hydrodynamics (velocity, flow rate, aperture) on microbially mediated calcite precipitation. Our experimental results demonstrate that a feedback mechanism exists between the gradual reduction in fracture aperture due to precipitation, and its effect on the local fluid velocity. This feedback results in mineral fill distributions that focus flow into a small number of self-organizing channels that remain open, ultimately controlling the final aperture profile that governs flow within the fracture. This hydrodynamic coupling can explain field observations of discrete groundwater flow channeling within fracture-fill mineral geometries where strong evidence of microbial activity is reported
In-Home Training for Fathers of Children with Autism: A Follow up Study and Evaluation of Four Individual Training Components
Literature regarding fathers of children with autism remains sparse, and because mothers are the more common intervening parent, few training methods have focused on fathers. Thus, we sought to evaluate effects of in-home training directed at fathers and their ability to train mothers in the same manner in which they were trained. Fathers were taught four skills commonly associated with in-home training interventions for parents of children with autism: following the childâs lead, imitation with animation, commenting on the child, and expectant waiting. Father skills were evaluated twice a week for 12Â weeks during videotaped in-home fatherâchild play sessions. Analyses included visual inspection of graphed data and statistical analyses of father skill acquisition, mother skill acquisition, and child behaviors with both parents. A multivariate repeated measures analysis of 18 dyads revealed significant increases in frequencies of fathersâ imitation with animation, expectant waiting, and commenting on the child. Child initiating rates increased significantly as did frequencies of child non-speech vocalizations. Analysis of mothers revealed significant increases in frequencies of imitation with animation, expectant waiting, and following the childâs lead. Child behaviors had similar results for father and mother sessions. Findings are consistent with those from our first study indicating that fathers can effectively implement skills that promote fatherâchild social interactions and that children respond positively to this approach
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