Bulletin 13 - Physics in the High School

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Functionality of physical activity referral schemes (PARS): a systematic review

Background: Physical activity (PA) is vital to maintaining good health. However, WHO estimates that 60% of the world’s population are inadequately active. To enhance PA, Physical Activity Referral Schemes (PARS) have been established by some countries. Objective: This study examined the functionality of the PARS process across different countries. Methods: This systematic review was performed and reported in accordance with the PRISMA guidelines. Sixteen electronic databases were searched from January 1990 to May 2020. PARS studies, published in English language and in peer-reviewed journals, that reported adherence, outcomes, disease conditions, interventions, facilitators and barriers, were included in this review. Results: Twenty-seven studies conducted across eight countries met the inclusion criteria. Most patients were referred for sedentary/inactivity reasons and supervised group-based activities was the most used intervention. Participants’ average adherence rate was 77.5%. Adherence was either facilitated or hindered by type of support provided during and after intervention period. Inclusion of PA allied health specialist in the intervention enhanced positive health outcomes. Conclusion: PARS is a key driver and motivator for individuals to undertake and adhere to PA interventions. Utilisation of guidelines on evidence-based interventional PA for different types of diseases, effective use of common group supervised activities and the involvement of PA specialists may aid PA adherence and foster positive health outcomes

Physical activity promotion: a systematic review of the perceptions of healthcare professionals

Physical activity (PA) is a cost-effective and non-pharmacological foundation for the prevention and management of chronic and complex diseases. Healthcare professionals could be viable conduits for PA promotion. However, the evidence regarding the effectiveness and benefits of the current forms of PA promotion are inconclusive. Healthcare professionals’ perceptions on key determinants impact on the optimum promotion of PA were explored in this review. Thirty-four (34) studies were identified after systematically searching seven databases for peer-reviewed articles published within the last decade. PA advice or counselling was the most recorded form of PA promotion, limited counselling time was the most reported obstacle while providing incentives was viewed as a key facilitator. There is widespread consensus among healthcare professionals (HCPs) on some aspects of PA promotion. Utilisation of all PA promotional pathways to their full potential could be an essential turning point towards the optimal success of PA promotional goals. Hence, strategies are required to broaden chronic disease treatment methods to include preventive and integrative PA promotion approaches particularly, between frontline HCPs (e.g., GPs) and PA specialists (e.g., EPs). Future studies could explore the functionality of GP to EP referral pathways to determining what currently works and areas requiring further development

Experimental progress in simultaneous ionization-excitation processes

Mark Stevenson, Mevlut Dogan and Albert Crow

The ‘PRICE’ of Physical Activity Referral Schemes (PARS): stakeholders’ recommendations for delivering quality care to patients

Evidence-based strategies are needed to curb the growing cases of physical inactivity related morbidities. Delivering holistic care through collaborative shared decision making could boost the effectiveness of physical activity referral schemes (PARS) and foster the quality of care for patients with multimorbidity. A qualitative study involving semi-structured telephone interviews was utilised to gain insights from Australian PARS stakeholders (general practitioners, exercise physiologists, and patients). A pluralistic evaluation approach was employed to explore and integrate participants’ opinions and experiences of PARS and their recommendations were used to develop a model for quality care delivery in PARS initiatives. Five overarching themes: promote, relate, incentivise, communicate, and educate were identified as the ‘PRICE’ for developing effective and functional PARS programmes that foster quality patient care. It was evident that PARS programmes or policies aimed at optimising publicity, encouraging incentives, improving interdisciplinary information sharing and professional relationships between patients and healthcare professionals can transform healthcare delivery and provide top quality PARS care services to patients. Therefore, governments, healthcare systems, and PARS administrators can translate and leverage the insights from this study to optimise the delivery of high quality care to PARS patients

Apoptotic Cells Deliver Processed Antigen to Dendritic Cells for Cross-Presentation

Antigen derived from engulfed apoptotic cells can be cross-presented by dendritic cells (DCs) for the generation of major histocompatibility class I/peptide complexes. While the early events of recognition and internalization of the dying cell have been characterized, the antigen-processing pathway or pathways remain unknown. We established a mouse model assaying for the activation of polyclonal T cells reactive to antigen derived from apoptotic cells, and demonstrated two distinct pathways for the trafficking of exogenous epitopes. In the first, exogenous antigen is dependent on the DC's expression of a functional transporter associated with antigen processing (TAP). Surprisingly, we found evidence that a second pathway exists in which transfer of processed antigen from the dying cell allows formation of major histocompatibility class I/peptide complexes in TAP-deficient DCs. In vivo data suggest that in situations of stress (e.g., viral infection), this latter pathway may be more efficient, illustrating that dying cells may preselect immunologically important antigenic determinants

Anaesthetic research in low- and middle-income countries.

In this issue of Anaesthesia, Kwikiriza et al. [1] report a randomised controlled trial comparing the analgesic effects of intrathecal morphine with ultrasound-guided transversus abdominis plane block after caesarean section at a Ugandan Regional Referral Hospital. The publication of this study, authored by an international team, represents an important example of the role of academic anaesthesia in global health.NIHR Global Health Research Group on Neurotraum

Differential Cross Sections and Cross-Section Ratios for the Electron-Impact Excitation of the Neon 2p⁵3s Configuration

Electron-impact differential cross-section measurements for the excitation of the 2p53s configuration of Ne are reported. The Ne cross sections are obtained using experimental differential cross sections for the electron-impact excitation of the n = 2 levels of atomic hydrogen [Khakoo et al., Phys. Rev. A 61, 012701-1 (1999)], and existing experimental helium differential cross-section measurements, as calibration standards. These calibration measurements were made using the method of gas mixtures (Ne and H followed by Ne and He), in which the gas beam profiles of the mixed gases are found to be the same within our experimental errors. We also present results from calculations of these differential cross sections using the R-matrix and unitarized first-order many-body theory, the distorted-wave Born approximation, and relativistic distorted-wave methods. Comparison with available experimental differential cross sections and differential cross-section ratios is also presented