488 research outputs found

    The Role of Institutions in European Patterns of Work and Retirement

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    This paper uses the Survey of Health, Ageing and Retirement in Europe (SHARE) to investigate the role of pension and social security institutions in shaping the European patterns of work and retirement. We provide evidence on the extent of “unused capacity” in labor force, on pathways to retirement and on the relationship between actual health status and disability take up. We find that institutional differences between countries explain much of the cross-national differences in work and retirement, while differences in health and demographics play only a minor role.Aging, employment, retirement, health, disability, social security institutions, SHARE

    Development of Injuries Prevention Policies in Mexico: A Big Data Approach

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    Considering that Mexican injuries prevention strategies have been focused on injuries caused by car accidents and gender violence, a whole analysis of the injuries registered are performed in this paper to have a wider overview of those agents that can cause injuries around the country. Taking into account the amount of information from both public and private sources, obtained from dynamic cubes reported by the Minister of Health, Big Data strategies are used with the objective of finding an appropriate extraction such as to identify the real correlations between the different variables registered by the Health Sector. The results of the analysis show areas of opportunity to improve the public policies on the subject, particularly in diminishing wounds at living place, public road (pedestrians) and work

    Produção de sementes, qualidade fisiológica e identificação de genótipos de alface termotolerantes.

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    O objetivo neste trabalho foi identificar as diferenças de germinação de sementes de vinte cultivares de alface em condições de temperatura ideal 20° C

    Conservação de sementes de hortaliças na agricultura familiar.

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    Evaluation of the traditional and revised world health organization classifications of dengue cases in Brazil

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    OBJECTIVE: Dengue is a worldwide public health problem with approximately 50 million cases reported annually. The World Health Organization proposed a revised classification system in 2008 to more effectively identify the patients who are at increased risk of complications from dengue. Few studies have validated this new classification system in clinical practice. We conducted a cross-sectional study of patients hospitalized for dengue in Dourados, Mato Grosso do Sul, Brazil, to evaluate the capacity of the two classification systems for detecting severe cases of dengue. MATERIALS AND METHODS: We conducted a cross-sectional study of survey data from the medical records of patients admitted to the University Hospital of the Federal University of Grande Dourados under clinical suspicion of dengue during an epidemic from September 2009 to April 2010. RESULTS: The distribution of patients according to the traditional classification system was as follows: dengue fever, 150/181 (82.9%); dengue hemorrhagic fever, 27/181 (14.9%); and dengue hemorrhagic shock, 4/181 (2.2%). Using the revised classification system, the distribution was as follows: dengue without warning signs, 45/181 (24.3%); dengue with warning signs, 107/181 (59.1%); and severe dengue, 29/181 (15.6%). Of the 150 patients classified as having dengue fever, 105 (70%) were reclassified as having dengue with warning signs or severe dengue. CONCLUSION: These data demonstrate that the revised classification system has greater discriminatory power for detecting patients at risk of progression to severe disease and those needing hospitalization

    Sales Prediction through Neural Networks for a Small Dataset

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    Sales forecasting allows firms to plan their production outputs, which contributes to optimizing firms' inventory management via a cost reduction. However, not all firms have the same capacity to store all the necessary information through time. So, time-series with a short length are common within industries, and problems arise due to small time series does not fully capture sales' behavior. In this paper, we show the applicability of neural networks in a case where a company reports a short time-series given the changes in its warehouse structure. Given the neural networks independence form statistical assumptions, we use a multilayer-perceptron to get the sales forecasting of this enterprise. We find that learning rates variations do not significantly increase the computing time, and the validation fails with an error minor to five percent

    The Promotion of Graduate Programs through Clustering Prospective Students

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    The promotion of academic programs, particularly at graduate levels, emerges as a response to market changes. In general, graduate programs are not a first order necessity which makes necessary the right promotion of such programs guarantee the attraction of prospective students, which enroll in some of them, which is essential for the financial sustainability of universities. Notably, the last one is a crucial problem for private universities. In this paper, we analyze the prospective students that enroll in a private to design better promotion strategies by using on data gathered by online sources. Specifically, we use clustering techniques to define marketing strategies based on segments of students. We find that age and city are crucial to promoting graduate programs while marital status and sex does not impact the decision of students in the university that we analyze

    The Health of Disability Insurance Enrollees: An International Comparison

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    Rising costs of disability insurance (DI) programs are putting increased strain on central government budgets, yet little is known about how well countries target those in the poorest health. In this paper, we use the SHARE and HRS surveys to measure the average health of people aged 50-64 receiving DI, and the effectiveness of the DI safety net in covering those in poor health. The U.S. and Denmark appear successful at targeting benefits, with France and Belgium less so. These measures can also be used over time to evaluate country-level policy changes

    Synthesis, In Vitro Antiproliferative And Anti-mycobacterium Tuberculosis Activities Of Novel β-carboline Derivatives

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    Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)A series of β-carboline derivatives with amino or guanidinium were synthesized and evaluated in vitro against anti-Mycobacterium tuberculosis and for antiproliferative activities against nine human cancer cell lines. The compounds 1-(4-hydroxyphenyl)-3-carboxamide(ethylamine) β-carboline (24.9 μg mL-1) and 1-(4-methoxyphenyl)-3-carboxamide(ethylamine) β-carboline (26.9 μg mL-1) were the most active against M. Tuberculosis (MTB). Compounds 1-(4-hydroxyphenyl)-3-carboxamide(ethylamine) β-carboline and 1-(4-methoxyphenyl)-3-carboxamide(propylamine) β-carboline, which had the same substituted groups, inhibited the growth of all human tumor cell lines with growth inhibitory activity (GI50) values from 1.37 to 9.20 mmol L-1. Also in this series, compounds 1-(4-hydroxyphenyl)-3-carboxamide(propylamine) β-carboline and 1-(3-nitrophenyl)-3-carboxamide(propylamine) β-carboline demonstrated significant activity against NCI/ADR cells. Among compounds with a terminal guanidine group, compounds 1-(4-hydroxyphenyl)-3-carboxamide(ethyl)guanidine β-carboline (27.8 μg mL-1) and 1-(3-nitrophenyl)-3-carboxamide(ethyl) guanidine β-carboline (37.4 μg mL-1) demonstrated the greatest activity against MTB. Additionally, compounds 1-(4-methoxyphenyl)-3-carboxamide(ethyl)guanidine β-carboline (GI50 = 0.45 mmol L-1) effectively inhibited growth and was highly selective against NCI/ADR. The in silico study revealed that 1-(4-hydroxyphenyl)-3-carboxamide(ethylamine) β-carboline, 1-(4-methoxyphenyl)-3-carboxamide(ethylamine) β-carboline, 1-(4-hydroxyphenyl)-3-carboxamide(propylamine) β-carboline, 1-(4-methoxyphenyl)-3-carboxamide(propylamine) β-carboline and 1-(3-nitrophenyl)-3-carboxamide(propylamine) β-carboline compounds follow the rules established by Lipinski, suggesting that this compound has no problems with oral bioavailability. © 2016 Sociedade Brasileira de Química.27813981405CAPES, Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorCNPq, Conselho Nacional de Desenvolvimento Científico e TecnológicoCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq
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