Milk related excipients in medications: concerns with cow’s milk protein allergy

Abstract in proceedings of the Fourth International Congress of CiiEM: Health, Well-Being and Ageing in the 21st Century, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from 3–5 June 2019.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.info:eu-repo/semantics/publishedVersio

Modificações na concha de lapas em fontes hidrotermais de superfície

Copyright © 2012 APRH.Os organismos calcários são conhecidos por serem sensíveis à água do mar acidificada, e têm sido apontados como potenciais sentinelas para estudos sobre acidificação do oceano. As lapas estão entre os organismos que caracterizam a zona intertidal e nos Açores, podendo também ser encontradas em locais com actividade hidrotermal de superfície, onde a acidez da água do mar na proximidade das fontes hidrotermais é naturalmente mais elevada devido à liberação de CO2. Durante uma visita ocasional para avaliar a ocorrência e abundância de algas no intertidal encontraram-se vários espécimes de Patella candei gomesii (Patellidae) com conchas aberrantes, na proximidade de fontes hidrotermais. Estes indivíduos, colectados sob tais condições exibiam conchas frágeis, quase transparentes, com espessura muito reduzida.ABSTRACT: Calcareous organisms are known to be sensitive to acidified seawater, and they have been reported as potential sentinels for ocean acidification studies. Limpets are among the organisms that characterise intertidal zones, and in the Azores can also be found at sites with shallow water hydrothermal activity, where the acidity of seawater in the vicinity of hydrothermal vents is naturally higher due to CO2 release. During an occasional intertidal survey on the occurrence and abundance of intertidal algae we found limpets with abnormal shells, and specimens of Patella candei gomesii (Patellidae) collected under such conditions exhibited weak and almost transparent shells with reduced shell thickness

Investigating natural acidified marine environments

Jornadas "Ciência nos Açores – que futuro?", Ponta Delgada, 7-8 de Junho de 2013.As fontes hidrotermais de superfície constituem laboratórios naturais para investigar ambientes marinhos naturalmente acidificados como modelos para a avaliação dos efeitos da acidificação dos oceanos. Os organismos nestas zonas estão sujeitos às condições acídicas, bem como às variações de temperatura e exposição a produtos químicos, incluindo a libertação de metais pesados. Ambientes extremos podem promover alterações nas comunidades, organismos ou processos fisiológicos. Algumas das estratégias, mecanismos, adaptações ou até mesmo especiação (novas espécies) poderiam mostrar como viver nesses ambientes e ajudar a descobrir organismos suficientemente sensíveis para atuar como sentinelas (bioindicadores) e, eventualmente adaptações biológicas associadas com potencial uso biotecnológico. Algumas espécies, devido à sua estrutura calcária (sensíveis a condições ácidas) requerem uma atenção especial. As fontes hidrotermais de superfície são uma característica peculiar dos Açores. Representam ambientes únicos e constituem patrimônio natural do litoral dos Açores. No presente projeto pretende-se investigar os efeitos da atividade hidrotermal em comunidades subtidais macrobentónicas em São Miguel, com uma abordagem inovadora no estudo dos efeitos da acidificação dos oceanos. A comparação entre locais com atividade hidrotermal e locais sem atividade hidrotermal irá fornecer informações sobre as diferenças na distribuição das espécies. Esta informação será complementada com a investigação sobre as respostas de organismos selecionados aos efeitos de viver sob a influência das fontes hidrotermais.ABSTRACT: Shallow water hydrothermal vents constitute natural laboratories to investigate natural acidified marine environments as models for the evaluation of the effects of ocean acidification. Organisms at those areas are subject to acidic conditions, as well as to temperature variations and exposure to chemicals, including the release of heavy metals. The extreme environment can promote changes on the communities, organisms or physiological processes. Some of the strategies, mechanisms, adaptations or even speciation (new species) could show how to live in these environments and help discovering organisms sufficiently sensitive to act as early sentinels (bioindicators) and possible associated biological adaptations with potential biotechnological use. Some species, due to their calcareous structure (sensitive to acidic conditions) need special attention. Shallow water hydrothermal vents are striking features of the Azores. They represent unique environments and constitute a natural patrimony of the Azorean coastline. In the present project we investigate the effects of hydrothermal activity on subtidal macrobenthic communities in the island of São Miguel, in an innovative approach to study ocean acidification effects. A comparison between sites with hydrothermal activity and sites without hydrothermal activity will provide information on species distribution differences. This information will be complemented with research on the responses of selected organisms to the effects of living under the vents influence

Impact of active efflux in the development of MDR phenotypes in Staphylococcus aureus

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Differences in the Prevalence of Non-Communicable Disease between Slum Dwellers and the General Population in a Large Urban Area in Brazil.

Residents of urban slums are at greater risk for disease than their non-slum dwelling urban counterparts. We sought to contrast the prevalences of selected non-communicable diseases (NCDs) between Brazilian adults living in a slum and the general population of the same city, by comparing the age and sex-standardized prevalences of selected NCDs from a 2010 survey in Pau da Lima, Salvador Brazil, with a 2010 national population-based telephone survey. NCD prevalences in both populations were similar for hypertension (23.6% (95% CI 20.9⁻26.4) and 22.9% (21.2⁻24.6), respectively) and for dyslipidemia (22.7% (19.8⁻25.5) and 21.5% (19.7⁻23.4)). Slum residents had higher prevalences of diabetes mellitus (10.1% (7.9⁻12.3)) and of overweight/obesity (46.5% (43.1⁻49.9)), compared to 5.2% (4.2⁻6.1) and 40.6% (38.5⁻42.8) of the general population in Salvador. Fourteen percent (14.5% (12.1⁻17.0)) of slum residents smoked cigarettes compared to 8.3% (7.1⁻9.5) of the general population in Salvador. The national telephone survey underestimated the prevalence of diabetes mellitus, overweight/obesity, and smoking in the slum population, likely in part due to differential sampling inside and outside of slums. Further research and targeted policies are needed to mitigate these inequalities, which could have significant economic and social impacts on slum residents and their communities

A Highly Pathogenic Strain of Staphylococcus sciuri Caused Fatal Exudative Epidermitis in Piglets

Staphylococcus sciuri are important human pathogens responsible for endocarditis, peritonitis, septic shock, urinary tract infection, pelvic inflammatory disease and wound infections. However, little information is known regarding the pathogenicity of S. sciuri to animals. From the pericardial fluid of a diseased piglet with exudative epidermitis (EE), we isolated a strain of Staphylococcus in pure culture. Surprisingly, this isolate was a member of S. sciuri rather than S. hyicus as identified by its biochemical traits and also by analysis of 23S ribosomal DNA using Internal Transcribed Spacer PCR. In addition, inoculation of newborn piglets with 1×10(10) CFU of the isolate by oral feeding or intra-muscular injection successfully reproduced EE in piglets, which suggested that the oral intake of the pathogen by the animals is one of the major routes of exposure. These unexpected findings prioritized S. sciuri as important zoonotic agents, which may have ramifications for human medicine

Self-perceived oral health assessment of institutionalized elderly of Viseu

Background: Self-perception of oral health is a multidimensional measure that, reflects the subjective experience of individuals about their physical and psychosocial well-being, determines the search for prevention and dental treatments.Objective: The assessment of the self-perception of oral health status of institutionalized elderly through the Geriatric Oral Health Assessment Index (GOHAI) and the verification of the association between the GOHAI and the various socio-demographic variables and oral health behaviors analyzed. Participants and methods: With this study we intended to conduct a cross-sectional observational epidemiological study with institutionalized elderly. Data were collected from a sample of 56 institutionalized elderly of the Mariana Seixas Foundation and the Viscondessa São Caetano Nursing Home in Viseu, Portugal. For this we used a questionnaire that allows to evaluate the self-perception of oral health, the Geriatric Oral Health Assessment Index (GOHAI). Results: It was found that the elderly generally favorably assessed their oral health, with 42.9% of the participants having a high self-perception of their oral health (values between 34-36); 28.6% have a moderate perception (values between 30-33) and the same percentage of individuals (28.6%) have a low perception (values below 30) of their oral health. The GOHAI scores obtained are associated with gender, educational level and oral health behaviors. Conclusion: Literacy can influence the level of self-perception of oral health. Therefore, the development of measures to assess oral health status is essential for the evolution of scientific knowledge based on geriatric dentistry in order to determine oral health promotion strategies among the institutionalized elderly.info:eu-repo/semantics/publishedVersio